Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine- seeking behavior: Effects of selective antagonists and agonists

Journal of Pharmacology and Experimental Therapeutics

Volumn 294, Issue 2, 2000, Pages 680-687

  Khroyan, Taline V ^a,c   Barrett Larimore, Rita L ^b,c   Rowlett, James K ^c   Spealman, Roger D ^c  

^a SRI INTERNATIONAL   (United States)

^b MORGAN STATE UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4,4A,10B TETRAHYDRO 4 PROPYL 2H,5H [1]BENZOPYRANO[4,3 B][1,4]OXAZIN 9 OL; 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; COCAINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG DEPENDENCE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; INTRINSIC SYMPATHOMIMETIC ACTIVITY; MONKEY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; STIMULUS RESPONSE; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; MALE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SAIMIRI; SELF ADMINISTRATION;

EID: 0033925382     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Ariens EJ (1983) Intrinsic activity: Partial agonists and partial antagonists. J Cardiovasc Pharmacol 5:S8-S15.
2. Audinot V, Newman-Tancredi A, Gobert A, Rivet J-M, Brocco M, Lejeune F, Gluck L, Deposte I, Bervoets K, Dekeyne A and Millan MJ (1998) A comparative in vitro pharmacological characterization of the novel dopamine D3 receptor antagonist (+)-S 14297, Nafadotride, GR 103,691 and U 99194. J Pharmacol Exp Ther 287:187-197.
3. Bergman J, Madras BK and Spealman RD (1991) Behavioral effects of D1 and D2 dopamine receptor antagonists in squirrel monkeys. J Pharmacol Exp Ther 258: 910-917.
4. Bergman J, Rosenzweig-Lipson S and Spealman RD (1995) Differential effects of dopamine D1 and D2 receptor agonists on schedule-controlled behavior of squirrel monkeys. J Pharmacol Exp Ther 273:40-48.
5. Britton DR, Asin KE, Yahiro L, Curzon P, Bednarz L and Williams J (1991) D1 dopamine receptor agonists induce forelimb clonus. Soc Neurosci Abstr 17:638.
6. Caine SB and Koob GF (1993) Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science (Wash DC) 260:1814-1816.
7. Callahan PM, Piercy MF and Cunningham (1992) Effects of the putative dopamine autoreceptor antagonists (+ )-AJ 76 and (+)-UH 232 on the discriminative stimulus properties of cocaine. Psychopharmacology 107:73-77.
8. Carey GJ and Spealman RD (1998) Models of neurological disease (substance abuse): Self-administration in monkeys, in Current Protocols in Pharmacology (Enna S, Williams M, Ferkany J, Kenakin T, Porsolt R and Sullivan J eds) pp 10.5.1-10.5.15, John Wiley and Sons, New York.
9. Carroll ME and Comer SD (1996) Animal models of relapse. Exp Clin Psychopharmacol 4:11-18.
10. Dejong W (1994) Relapse prevention: An emerging technology for promoting long-term drug abstinence. Int J Addictions 29:681-705.
11. De Vries TJ, Schoffelmeer ANM, Binnekade R and Vanderschuren LJMJ (1999) Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug self-administration. Psychopharmacology 143:254-260.
12. de Wit H and Stewart J (1981) Reinstatement of cocaine-reinforced responding in the rat. Psychopharmacology 75:134-143.
13. Freedman SB, Patel S, Marwood R, Emms F, Seabrook GR, Knowles MR and McAllister G (1994) Expression and pharmacological characterization of the human D3 receptor. J Pharmacol Exp Ther 268:417-426.
14. Goldberg SR, Kelleher RT and Morse WH (1975) Second-order schedules of drug injection. Fed Proc 34:1771-1776.
15. Grech DM, Spealman RD and Bergman J (1996) Self-administration of D1 receptor agonists by squirrel monkeys. Psychopharmacology 125:97-104.
16. Jaffe JH, Cascella NG, Kumor KM and Sherer MA (1989) Cocaine-induced cocaine craving. Psychopharmacology 97:59-64.
17. Katz JL and Witkin JM (1992) Selective effects of D1 dopamine receptor agonist, SKF 38393, on behavior maintained by cocaine injection in squirrel monkeys. Psychopharmacology 109:241-244.
18. Lin CW, Bianchi BR, Miller TR, Stashko MA, Wang SS, Curzon P, Bednarz L, Asin KE and Britton DR (1996) Persistent activation of the dopamine D1 receptor contributes to prolonged receptor desensitization: Studies with A-77636. J Pharmacol Exp Ther 276:1022-1029.
19. McKay JR, Rutherford MJ, Alterman AI, Cacciola JS and Kaplan MR (1995) An examination of the cocaine relapse process. Drug Alcohol Depend 38:35-43.
20. Mello NK and Negus SS (1996) Preclinical evaluation of pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures. Neuropsychopharmacology 14:375-424.
21. Moore RJ, Vinsant SL, Nader MA, Porrino LJ and Friedman DP (1998) Effect of cocaine self-administration on striatal dopamine D1 receptors in rhesus monkeys. Synapse 28:1-9.
22. Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz J-C, Everitt BJ and Sokoloff P (1999) Selective inhibition of cocaine-seeking behavior by a partial dopamine D3 receptor agonist. Nature (Lond) 400:371-375.
23. Platt DM, Rowlett JK and Spealman RD (2000) Dissociation of the cocaine-antagonist properties and motoric effects of the D1 receptor partial agonists SKF 83959 and SKF 77434. J Pharmacol Exp Ther 293:1017-1026.
24. Pugsley TA, Davis MD, Akunne HC, Mackenzie RG, Shih YH, Damsma G. Wikstrom H, Whetzel SZ, Georgic LM, Cooke LW, Demattos SB, Corbin AE, Glase SA, Wise LD, Dijkstra D and Heffner TG (1995) Neurochemical and functional characterization of the preferentially selective D3 agonist PD-128907. J Pharmacol Exp Ther 275:1355-1366.
25. Pulvirenti L, Balducci C, Piercy M and Koob GF (1998) Characterization of the effects of the partial dopamine agonist terguride on cocaine self-administration in the rat. J Pharmacol Exp Ther 286:1231-1238.
26. Robbins SJ, Ehrman RN, Childress AR and O'Brien CP (1997) Relationships among physiological and self-reported responses produced by cocaine-related cues. Addict Behav 22:157-167.
27. Roberts DCS and Ranaldi R (1995) Effect of dopaminergic drugs on cocaine reinforcement. Clin Neuropharmacol 18:S84-S95.
28. Self DW, Barnhart WT, Lehman DA and Nestler EJ (1996) Opposite modulation of cocaine-seeking behavior by D1 and D2-like dopamine receptor agonists. Science (Wash DC) 271:1586-1589.
29. Self DW and Nestler EJ (1998) Relapse to drug-seeking: Neural and molecular mechanisms. Drug Alcohol Depend 51:49-60.
30. Simpson DD, Joe GW, Fletcher BW, Hubbard RL and Anglin MD (1999) A national evaluation of treatment outcomes for cocaine dependence. Arch Gen Psychiatry 56: 507-514.
31. Spealman RD (1995) Discriminative stimulus effects of cocaine in squirrel monkeys: Lack of antagonism by the dopamine D2 partial agonists terguride, SDZ 208-911, and SDZ 208-912. Pharmacol Biochem Behav 51:661-665.
32. Spealman RD (1996) Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys. J Pharmacol Exp Ther 278:1128-1137.
33. Spealman RD, Barrett-Larimore RL, Rowlett JK, Platt DM and Khroyan TV (1999) Pharmacological and environmental determinants of relapse to cocaine-seeking behavior. Pharmacol Biochem Behav 64:327-336.
34. Spealman RD, Bergman J, Madras BK, Kamien JB and Melia KF (1992) Role of D1 and D2 dopamine receptors in the behavioral effects of cocaine. Neurochem Int 20:147S-152S.
35. Spealman RD, Bergman J and Rosenzweig-Lipson S (1997) Differential modulation of behavioral effects of cocaine by low- and high-efficacy D1 agonists. Psychopharmacology 133:283-292.
36. Tran-Nguyen LTL, Fuchs RA, Coffey GP, Baker DA, O'Dell LE and Neisewander JL (1998) Time-dependent changes in cocaine-seeking behavior and extracellular dopamine levels in the amygdala during cocaine withdrawal. Neuropsychopharmacalogy 19:48-59.
37. Undie AS, Weinstock J, Sarau HM and Friedman E (1994) Evidence for a distinct D1-like receptor that couples to activation of phosphoinositide metabolism in brain. J Neurochem 62:2045-2048.
38. Vanover KE, Piercey MF and Woolverton WL (1993) Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ 76 or clozapine. J Pharmacol Exp Ther 266:780-789.
39. Weed MR and Woolverton WL (1995) The reinforcing effects of dopamine D1 receptor agonists in rhesus monkeys. J Pharmacol Exp Ther 275:1367-1374.
40. Weissenborn R, Deroche V, Koob GF and Weiss F (1996) Effects of dopamine agonists and antagonists on cocaine-induced operant responding for a cocaine-associated stimulus. Psychopharmacology 126:311-322.
41. Wise RA, Murray A and Bozarth MA (1990) Bromocriptine self-administration and bromocriptine-reinstatement of cocaine-trained and heroin-trained lever pressing in rats. Psychopharmacology 100:355-360.