The type IV phosphodiesterase inhibitors, Ro 20-1724 and rolipram, block the initiation of cocaine self-administration

Pharmacology Biochemistry and Behavior

Volumn 62, Issue 1, 1999, Pages 151-158

  Knapp, Clifford M ^a   Foye, Melissa M ^b   Ciraulo, Domenic A ^a   Kornetsky, Conan ^b  

^a Natl Inst Drug Abuse/Boston V   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cAMP; Cocaine; Food reinforcement; Phosphodiesterase inhibitor; Ro 20 1724; Rolipram; Self administration

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; COCAINE; CYCLIC AMP; PHOSPHODIESTERASE INHIBITOR; ROLIPRAM;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG SELF ADMINISTRATION; FOOD INTAKE; INTRAPERITONEAL DRUG ADMINISTRATION; LATENT PERIOD; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SIGNAL TRANSDUCTION;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; 4-(3-BUTOXY-4-METHOXYBENZYL)-2-IMIDAZOLIDINONE; ANALYSIS OF VARIANCE; ANIMALS; COCAINE; CONDITIONING, OPERANT; MALE; PHOSPHODIESTERASE INHIBITORS; PYRROLIDINONES; RATS; RATS, WISTAR; REINFORCEMENT (PSYCHOLOGY); ROLIPRAM; SELF ADMINISTRATION;

EID: 0032951464     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00154-3     Document Type: Article

References (26)

1. 1 receptor efficacy Eur. J. Pharmacol. Mol. Pharmacol. Sec. 188:1990;335-347.
2. Depoortere R.Y., Li D.H., Lane J.D., Emmett-Oglesby M.W. Parameters of self-administration of cocaine in rats under a progressive-ratio schedule. Pharmacol. Biochem. Behav. 45:1993;539-548.
3. Egawa T., Mishima Y., Matsumoto Y., Iwasaki K., Iwasaki K., Fujiwara M. Rolipram and its optical isomers, phosphodiesterase 4 inhibitors, attenuated the scopolamine-induced impairments of learning and memory in rats. Jpn. J. Pharmacol. 75:1997;275-281.
4. Fitzgerald L.W., Nestler E.J. Cocaine regulation of signal transduction pathways. Hammer R.P. The neurobiology of cocaine. Cellular and molecular mechanisms:1995;225-246 CRC Press, Boca Raton, FL.
5. Howell L.L. Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys. J. Pharmacol. Exp. Ther. 266:1993;894-903.
6. Hubner C.B., Koob G.F. Bromocriptine produces decreases in cocaine self-administration in the rat. Neuropsychopharmacology. 3:1990;101-108.
7. Iyo M., Maeda Y., Inada T., Kitao Y., Sasaki H., Fukui S. The effects of a selective cAMP phosphodiesterase inhibitor, rolipram, on methamphetamine-induced behavior. Neuropsychopharmacology. 13:1995;33-39.
8. 1 receptor agonists for stimulating adenylyl cyclase in squirrel monkey and rat. Eur. J. Pharmacol. 246:1993;39-44.
9. Kebabian J.W., Calne D.B. Multiple receptors for dopamine. Nature. 277:1979;93-96.
10. Kehr W., Debus G., Neumeister R. Effects of rolipram, a novel antidepressant on monoamine metabolism in rat brain. J. Neural Transmission. 63:1985;1-12.
11. 1 receptor agonist, suppresses cocaine self-administration. Soc. Neurosci. Abstr. 23:1997;1106.
12. Knapp, C. M.; Foye, M. M.; Ciraulo, D. A.; Kornetsky, C.: 5′-N-Ethylcarboxamidoadenosine (NECA), an adenosine receptor agonist, inhibits cocaine self-administration. Coll. Problems Drug Depend. Abstracts:74; 1998.
13. Krause W., Kuhne G. Pharmacokinetics of rolipram in the rhesus and cynomolgus monkeys, the rat and the rabbit. Studies on species differences. Xenobiotica. 18:1988;561-571.
14. Mumford G.K., Holtzman S.G. Methylxanthines elevate reinforcement threshold for electrical stimulation. role of adenosine receptors and phosphodiesterase inhibition Brain Res. 528:1990;32-38.
15. O'Donnell J.M. Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate. J. Pharmacol. Exp. Ther. 264:1993;1168-1178.
16. Reeves M.L., Leigh B.K., England P.J. The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Biochem. J. 241:1987;535-541.
17. Reid K., Guo T.-Z., Davies M.F., Maze M. Nidedipine, an L-type calcium channel blocker, restores the hypnotic response in rats made tolerant to the alpha-2 adrenergic agonist dexmedetomidine. J. Pharmacol. Exp. Ther. 283:1997;993-999.
18. Schneider H.H. Brain cAMP response to phosphodiesterase inhibitors in rats killed by microwave irradiation or decapitation. Biochem. Pharmacol. 33:1984;1690-1693.
19. Schneider H.H., Yamaguchi M., Andrews J.S., Stephens D.N. Discriminative stimulus properties of the stereoisomers of the phosphodiesterase inhibitor rolipram. Pharmacol. Biochem. Behav. 50:1995;211-217.
20. Schultz J.E., Schmidt B.H. Rolipram, a stereospecific inhibitor of calmodulin-independent phosphodiesterase, causes β-adrenoceptor subsensitivity in rat cerebral cortex. Naunyn Schmeidebergs Arch. Pharmacol. 333:1986;23-30.
21. Scuvee-Moreau J., Giesbers I., Dresse A. Effect of rolipram, a phosphodiesterase inhibitor and potential antidepressant, on the firing rate of central monoaminergic neurons in the rat. Arch. Int. Pharmacol. 288:1987;43-49.
22. 2-like dopamine receptor agonists. Science. 271:1996;1586-1589.
23. SigmaStat Statistical Software version 2.0, SPSS, Chicago, IL; 1997.
24. Stoof J.C., Kebabian J.W. Two dopamine receptors. biochemistry, physiology, and pharmacology Life Sci. 35:1984;2281-2296.
25. Wachtel H. Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3′,5′-monophosphate phosphodiesterase inhibitors. Psychopharmacology (Berlin). 77:1982;309-316.
26. Yamashita N., Yamauchi M., Baba J., Sawa A. Phosphodiesterase type 4 that regulates cAMP level in cortical neurons shows high sensitivity to rolipram. Eur. J. Pharmacol. 337:1997;95-102.