-
2
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-57.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
3
-
-
0033593572
-
Cell death in development
-
Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999;96:245-54.
-
(1999)
Cell
, vol.96
, pp. 245-254
-
-
Vaux, D.L.1
Korsmeyer, S.J.2
-
4
-
-
0037184909
-
Taking the study of cancer cell survival to a new dimension
-
Jacks T, Weinberg RA. Taking the study of cancer cell survival to a new dimension. Cell 2002;111:923-5.
-
(2002)
Cell
, vol.111
, pp. 923-925
-
-
Jacks, T.1
Weinberg, R.A.2
-
5
-
-
0037162713
-
Competition and compensation: Coupled to death in development and cancer
-
Abrams JM. Competition and compensation: coupled to death in development and cancer. Cell 2002;110:403-6.
-
(2002)
Cell
, vol.110
, pp. 403-406
-
-
Abrams, J.M.1
-
6
-
-
0037376405
-
The role of the Bcl-2 protein family in cancer
-
Coultas L, Strasser A. The role of the Bcl-2 protein family in cancer. Semin Cancer Biol 2003;13:115-23.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 115-123
-
-
Coultas, L.1
Strasser, A.2
-
7
-
-
0037364314
-
A role for mitochondrial enzymes in inherited neoplasia and beyond
-
Eng C, Kiuru M, Fernandez MJ, Aaltonen LA. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat Rev Cancer 2003;3:193-202.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 193-202
-
-
Eng, C.1
Kiuru, M.2
Fernandez, M.J.3
Aaltonen, L.A.4
-
8
-
-
0037376877
-
Angiogenesis and apoptosis
-
Folkman J Angiogenesis and apoptosis. Semin Cancer Biol 2003;13:159-67.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 159-167
-
-
Folkman, J.1
-
9
-
-
0033145416
-
Caspase activity sows the seeds of neuronal death
-
Yuan J, Yankner BA. Caspase activity sows the seeds of neuronal death. Nat Cell Biol 1999;1:E44-45.
-
(1999)
Nat Cell Biol
, vol.1
-
-
Yuan, J.1
Yankner, B.A.2
-
10
-
-
0034641936
-
Apoptosis in the nervous system
-
Yuan J, Yankner BA. Apoptosis in the nervous system. Nature (Lond) 2000;407: 802-9.
-
(2000)
Nature (Lond)
, vol.407
, pp. 802-809
-
-
Yuan, J.1
Yankner, B.A.2
-
11
-
-
0037180812
-
Points of control in inflammation
-
Nathan C. Points of control in inflammation. Nature 2002;420:846-852.
-
(2002)
Nature
, vol.420
, pp. 846-852
-
-
Nathan, C.1
-
12
-
-
0036514975
-
Autoimmune thyroid disease: New models of cell death in autoimmunity
-
Stassi G, De Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2002;2:195-204.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 195-204
-
-
Stassi, G.1
De Maria, R.2
-
13
-
-
0035318470
-
Apoptosis in autoimmune diseases
-
Eguchi K. Apoptosis in autoimmune diseases. Intern Med 2001;40:275-84.
-
(2001)
Intern Med
, vol.40
, pp. 275-284
-
-
Eguchi, K.1
-
14
-
-
0036226225
-
Bak and Bax function to limit adenovirus replication through apoptosis induction
-
Cuconati A, Degenhardt K, Sundararajan R, Anschel A, White E. Bak and Bax function to limit adenovirus replication through apoptosis induction. J Virol 2002;76:4547-58.
-
(2002)
J Virol
, vol.76
, pp. 4547-4558
-
-
Cuconati, A.1
Degenhardt, K.2
Sundararajan, R.3
Anschel, A.4
White, E.5
-
15
-
-
0036791781
-
Viral homologs of BCL-2: Role of apoptosis in the regulation of virus infection
-
Cuconati A, White E. Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection. Genes Dev. 2002;16:2465-78.
-
(2002)
Genes Dev
, vol.16
, pp. 2465-2478
-
-
Cuconati, A.1
White, E.2
-
16
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
17
-
-
0037313618
-
Coordinated regulation of life and death by RB
-
Chau BN, Wang JY. Coordinated regulation of life and death by RB. Nat Rev Cancer 2003;3:130-8.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 130-138
-
-
Chau, B.N.1
Wang, J.Y.2
-
18
-
-
0037317840
-
Inhibiting the p53-MDM2 interaction: An important target for cancer therapy
-
Chene P. Inhibiting the p53-MDM2 interaction: an important target for cancer therapy. Nat Rev Cancer 2003;3:102-9.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 102-109
-
-
Chene, P.1
-
19
-
-
0037240850
-
Nature's TRAIL-on a path to cancer immunotherapy
-
Smyth MJ, Takeda K, Hayakawa Y, Peschon JJ, van den Brink MR, Yagita H. Nature's TRAIL-on a path to cancer immunotherapy. Immunity 2003;18:1-6.
-
(2003)
Immunity
, vol.18
, pp. 1-6
-
-
Smyth, M.J.1
Takeda, K.2
Hayakawa, Y.3
Peschon, J.J.4
Van Den Brink, M.R.5
Yagita, H.6
-
20
-
-
0037267333
-
Validating survivin as a cancer therapeutic target
-
Altieri DC. Validating survivin as a cancer therapeutic target. Nat Rev Cancer 2003;3:46-54.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 46-54
-
-
Altieri, D.C.1
-
21
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza GL. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol 2000;35:71-103.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 71-103
-
-
Semenza, G.L.1
-
22
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock IF, Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 1989;49:4373-84.
-
(1989)
Cancer Res
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
23
-
-
0028006332
-
Manipulation and exploitation of the tumour environment for therapeutic benefit
-
Stratford IJ, Adams GE, Bremner JC, et al. Manipulation and exploitation of the tumour environment for therapeutic benefit. Int J Radiat Biol 1994;65:85-94.
-
(1994)
Int J Radiat Biol
, vol.65
, pp. 85-94
-
-
Stratford, I.J.1
Adams, G.E.2
Bremner, J.C.3
-
24
-
-
0034744448
-
Upregulation of Reg 1α and GW112 in the epithelium of inflamed colonic mucosa
-
Shinozaki S, Nakamura T, Iimura M, et al. Upregulation of Reg 1α and GW112 in the epithelium of inflamed colonic mucosa. Gut 2001;48:623-9.
-
(2001)
Gut
, vol.48
, pp. 623-629
-
-
Shinozaki, S.1
Nakamura, T.2
Iimura, M.3
-
25
-
-
0034721920
-
Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach
-
Angell JE, Lindner DJ, Shapiro PS, Hofmann ER, Kalvakolanu DV. Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-β and retinoic acid combination, using a genetic approach. J Biol Chem 2000;275:33416-26.
-
(2000)
J Biol Chem
, vol.275
, pp. 33416-33426
-
-
Angell, J.E.1
Lindner, D.J.2
Shapiro, P.S.3
Hofmann, E.R.4
Kalvakolanu, D.V.5
-
26
-
-
0035914435
-
Hirst J GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH: Ubiquinone oxidoreductase (complex I)
-
Fearnley IM, Carroll J, Shannon RJ, Runswick MJ, Walker JE, Hirst J GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH: ubiquinone oxidoreductase (complex I). J Biol Chem 2001;276:38345-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 38345-38348
-
-
Fearnley, I.M.1
Carroll, J.2
Shannon, R.J.3
Runswick, M.J.4
Walker, J.E.5
-
27
-
-
0033910295
-
Chromosomal localization of human GRIM-19, a novel IFN-β and retinoic acid-activated regulator of cell death
-
Chidambaram NV, Angell JE, Ling W, Hofmann ER, Kalvakolanu DV. Chromosomal localization of human GRIM-19, a novel IFN-β and retinoic acid-activated regulator of cell death. J Interferon Cytokine Res 2000;20:661-5.
-
(2000)
J Interferon Cytokine Res
, vol.20
, pp. 661-665
-
-
Chidambaram, N.V.1
Angell, J.E.2
Ling, W.3
Hofmann, E.R.4
Kalvakolanu, D.V.5
-
28
-
-
0036333658
-
Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM 19, and inhibits interferon/retinoic acid-induced cell death
-
Seo T, Lee D, Shim YS, et al. Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM 19, and inhibits interferon/retinoic acid-induced cell death. J Virol 2002;76:8797-807.
-
(2002)
J Virol
, vol.76
, pp. 8797-8807
-
-
Seo, T.1
Lee, D.2
Shim, Y.S.3
-
29
-
-
0037451235
-
GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
-
Lufei C, Ma J, Huang G, et al. GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J 2003;22:1325-35.
-
(2003)
EMBO J
, vol.22
, pp. 1325-1335
-
-
Lufei, C.1
Ma, J.2
Huang, G.3
-
30
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 1998;95:2509-14.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
31
-
-
0032558412
-
Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria
-
Walter DH, Haendeler J, Galle J, Zeiher AM, Dimmeler S. Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria. Circulation 1998;98:1153-7.
-
(1998)
Circulation
, vol.98
, pp. 1153-1157
-
-
Walter, D.H.1
Haendeler, J.2
Galle, J.3
Zeiher, A.M.4
Dimmeler, S.5
-
32
-
-
1942460535
-
The subunit composition of the human NADH dehydrogenase obtained by rapid one step immunopurification
-
Murray JG, Zhang B, Taylor SW, et al. The subunit composition of the human NADH dehydrogenase obtained by rapid one step immunopurification. J Biol Chem 2003;28:28.
-
(2003)
J Biol Chem
, vol.28
, pp. 28
-
-
Murray, J.G.1
Zhang, B.2
Taylor, S.W.3
-
33
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996;86:147-57.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
34
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (Wash DC) 1997;275:1129-32.
-
(1997)
Science (Wash DC)
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
35
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
36
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. A model for p53-induced apoptosis. Nature (Lond) 1997;389:300-5.
-
(1997)
Nature (Lond)
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
37
-
-
0033594963
-
Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
-
Jakobsson PJ, Thoren S, Morgenstern R, Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA 1999;96:7220-5.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7220-7225
-
-
Jakobsson, P.J.1
Thoren, S.2
Morgenstern, R.3
Samuelsson, B.4
-
38
-
-
0028351565
-
The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
-
Zhan Q, Lord KA, Alamo I, Jr, et al. The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol Cell Biol. 1994;14:2361-71.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 2361-2371
-
-
Zhan, Q.1
Lord, K.A.2
Alamo Jr., I.3
-
39
-
-
0030597160
-
Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells
-
Matsumoto M, Minami M, Takeda K, Sakao Y, Akira S. Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells. FEBS Lett 1996;395:143-7.
-
(1996)
FEBS Lett
, vol.395
, pp. 143-147
-
-
Matsumoto, M.1
Minami, M.2
Takeda, K.3
Sakao, Y.4
Akira, S.5
-
40
-
-
0035879276
-
Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms
-
Maytin EV, Ubeda M, Lin JC, Habener JF. Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms. Exp Cell Res 2001;267:193-204.
-
(2001)
Exp Cell Res
, vol.267
, pp. 193-204
-
-
Maytin, E.V.1
Ubeda, M.2
Lin, J.C.3
Habener, J.F.4
-
41
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001;21:1249-59.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
42
-
-
0031020908
-
Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase
-
Yuan ZM, Huang Y, Ishiko T, Kharbanda S, Weichselbaum R, Kufe D. Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase. Proc Natl Acad Sci USA 1997;94:1437-40.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1437-1440
-
-
Yuan, Z.M.1
Huang, Y.2
Ishiko, T.3
Kharbanda, S.4
Weichselbaum, R.5
Kufe, D.6
-
43
-
-
0032490831
-
c-Abl tyrosine kinase can mediate tumor cell apoptosis independently of the Rb and p53 tumor suppressors
-
Theis S, Roemer K. c-Abl tyrosine kinase can mediate tumor cell apoptosis independently of the Rb and p53 tumor suppressors. Oncogene 1998;17:557-64.
-
(1998)
Oncogene
, vol.17
, pp. 557-564
-
-
Theis, S.1
Roemer, K.2
-
44
-
-
0033598783
-
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation
-
Cong F, Goff SP. c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation. Proc Natl Acad Sci USA 1999;96:13819-24.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13819-13824
-
-
Cong, F.1
Goff, S.P.2
-
45
-
-
0033600234
-
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
-
Gong JG, Costanzo A, Yang HQ, et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature (Lond) 1999;399:806-9.
-
(1999)
Nature (Lond)
, vol.399
, pp. 806-809
-
-
Gong, J.G.1
Costanzo, A.2
Yang, H.Q.3
-
46
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature (Lond) 1999;399:814-7.
-
(1999)
Nature (Lond)
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
-
47
-
-
0034625363
-
Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species
-
Sun X, Majumder P, Shioya H, et al. Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. J Biol Chem 2000;275:17237-40.
-
(2000)
J Biol Chem
, vol.275
, pp. 17237-17240
-
-
Sun, X.1
Majumder, P.2
Shioya, H.3
-
48
-
-
0034693878
-
Regulation of cell death by the Abl tyrosine kinase
-
Wang JY. Regulation of cell death by the Abl tyrosine kinase. Oncogene 2000;19:5643-50.
-
(2000)
Oncogene
, vol.19
, pp. 5643-5650
-
-
Wang, J.Y.1
-
49
-
-
0034655099
-
Flt3-ligand induces transient tumor regression in an ectopic treatment model of major histocompatibility complex-negative prostate cancer
-
Ciavarra RP, Somers KD, Brown RR, et al. Flt3-ligand induces transient tumor regression in an ectopic treatment model of major histocompatibility complex-negative prostate cancer. Cancer Res 2000;60:2081-4.
-
(2000)
Cancer Res
, vol.60
, pp. 2081-2084
-
-
Ciavarra, R.P.1
Somers, K.D.2
Brown, R.R.3
-
50
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin XM, Wang K, Gross A, et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (Lond) 1999;400:886-91.
-
(1999)
Nature (Lond)
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
|