St. John's Wort (Hypericum perforatum) induces overexpression of multidrug resistance protein 2 (MRP2) in rats: A 30-day ingestion study

Food and Chemical Toxicology

Volumn 42, Issue 6, 2004, Pages 995-1002

  Shibayama, Y ^a   Ikeda, R ^b   Motoya, T ^c   Yamada, K ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

AhR; Aryl hydorocarbon receptor; CDDP; Cis diamminedichloroplatinum; CYP; Cytochrome P450; Cytochrome P450 1A2; Glutathione S transferase P; Glutathione S transfrase P; GST P; MRP1; Multidrug resistance protein 2; Rat; St. John's Wort

Indexed keywords

ANTIDEPRESSANT AGENT; CARRIER PROTEIN; CYTOCHROME P450 1A2; ENZYME; GLUTATHIONE TRANSFERASE; GLYCOPROTEIN P; HYPERICUM PERFORATUM EXTRACT; LIVER ENZYME; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; HYPERICUM PERFORATUM; IMMUNOBLOTTING; INGESTION; KIDNEY; LIVER; MALE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT;

ADMINISTRATION, ORAL; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARRIER PROTEINS; CYTOCHROME P-450 CYP1A2; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HYPERICUM; LIVER; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR;

HYPERICUM; HYPERICUM PERFORATUM;

EID: 1942425487     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2004.02.012     Document Type: Article

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