Induction of hepatic mrp2 (cmrp/cmoat) gene expression in nonhuman primates treated with rifampicin or tamoxifen

Archives of Toxicology

Volumn 72, Issue 12, 1998, Pages 763-768

  Kauffmann, Hans Martin ^a   Keppler, Dietrich ^b   Gant, Timothy W ^c   Schrenk, Dieter ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Induction; Monkey liver; Multidrug resistance protein 2; Rifampicin; Tamoxifen

Indexed keywords

CARRIER PROTEIN; CYTOCHROME P450; DRUG METABOLITE; DRUG VEHICLE; GLUCURONIDE; GLUTATHIONE DERIVATIVE; MACROGOL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; RIFAMPICIN; SULFATE; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG ELIMINATION; FEMALE; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INTRAHEPATIC BILE DUCT; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INDUCTION; RHESUS MONKEY;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, NORTHERN; BLOTTING, WESTERN; FEMALE; GENE EXPRESSION REGULATION; GENES, MDR; LIVER; MACACA MULATTA; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RIFAMPIN; RNA, MESSENGER; TAMOXIFEN;

EID: 0032432662     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050571     Document Type: Article

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