MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

British Journal of Clinical Pharmacology

Volumn 54, Issue 6, 2002, Pages 610-616

  Gerloff, Thomas ^a   Schaefer, Melanie ^a   Johne, Andreas ^a   Oselin, Kersti ^a,b   Meisel, Christian ^a   Cascorbi, Ingolf ^c   Roots, Ivar ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TARTU   (Estonia)

^c UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Drug absorption; P glycoprotein; Pharmacogenetic effects

Indexed keywords

DIGOXIN; GENE PRODUCT; GLYCOPROTEIN P; RIFAMPICIN;

ADULT; AGE; ALLELE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CAUCASIAN; CLINICAL TRIAL; CODING; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; DNA POLYMORPHISM; DOSE CALCULATION; DRUG ABSORPTION; EXON; GENOTYPE; HEALTH STATUS; HUMAN; INTESTINE ABSORPTION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SINGLE NUCLEOTIDE POLYMORPHISM; TIME;

ABSORPTION; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AREA UNDER CURVE; CARDIOTONIC AGENTS; DIGOXIN; EXONS; GENES, MDR; HOMOZYGOTE; HUMANS; INTRONS; MALE; POLYMORPHISM, GENETIC;

EID: 0036904332     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2002.01691.x     Document Type: Article

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