-
1
-
-
4544306972
-
Dietary factors and Alzheimer's disease
-
Luchsinger JA, Mayeux R: Dietary factors and Alzheimer's disease. Lancet Neurol 2004, 3:579-587.
-
(2004)
Lancet Neurol
, vol.3
, pp. 579-587
-
-
Luchsinger, J.A.1
Mayeux, R.2
-
2
-
-
0033844944
-
Characterization of copper interactions with Alzheimer amyloid β peptides: Identification of an attomolar-affinity copper binding site on amyloid β1-42
-
Atwood CS, Scarpa RC, Huang X, Moir RD, Jones WD, Fairlie DP, Tanzi RE, Bush AI: Characterization of copper interactions with Alzheimer amyloid β peptides: identification of an attomolar-affinity copper binding site on amyloid β1-42. J Neurochem 2000, 75:1219-1233.
-
(2000)
J Neurochem
, vol.75
, pp. 1219-1233
-
-
Atwood, C.S.1
Scarpa, R.C.2
Huang, X.3
Moir, R.D.4
Jones, W.D.5
Fairlie, D.P.6
Tanzi, R.E.7
Bush, A.I.8
-
3
-
-
0032557425
-
Dramatic Aggregation of Alzheimer Abeta by Cu(II) Is Induced by Conditions Representing Physiological Acidosis
-
Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI: Dramatic Aggregation of Alzheimer Abeta by Cu(II) Is Induced by Conditions Representing Physiological Acidosis. J Biol Chem 1998, 273:12817-12826.
-
(1998)
J Biol Chem
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.5
Romano, D.M.6
Hartshorn, M.7
Tanzi, R.E.8
Bush, A.I.9
-
4
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
Lovell MA, Robertson JD, Teesdale WJ, Campbell JL, Markesbery WR: Copper, iron and zinc in Alzheimer's disease senile plaques. J Neurol Sci 1998, 158:47-52.
-
(1998)
J Neurol Sci
, vol.158
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
5
-
-
0037159210
-
Elevation of serum copper levels in Alzheimer's disease
-
Squitti R, Lupoi D, Pasqualetti P, Dal Forno G, Vernieri F, Chiovenda P, Rossi L, Cortesi M, Cassetta E, Rossini PM: Elevation of serum copper levels in Alzheimer's disease. Neurology 2002, 59:1153-1161.
-
(2002)
Neurology
, vol.59
, pp. 1153-1161
-
-
Squitti, R.1
Lupoi, D.2
Pasqualetti, P.3
Dal Forno, G.4
Vernieri, F.5
Chiovenda, P.6
Rossi, L.7
Cortesi, M.8
Cassetta, E.9
Rossini, P.M.10
-
6
-
-
0033601338
-
Cu(II) potentiation of alzheimer Abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction
-
Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, et al.: Cu(II) potentiation of alzheimer Abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. J Biol Chem 1999, 274:37111-37116.
-
(1999)
J Biol Chem
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
Hartshorn, M.A.4
Tyndall, J.D.5
Hanson, G.R.6
Stokes, K.C.7
Leopold, M.8
Multhaup, G.9
Goldstein, L.E.10
-
7
-
-
0037174856
-
2
-
2. J Biol Chem 2002, 277:40302-40308.
-
(2002)
J Biol Chem
, vol.277
, pp. 40302-40308
-
-
Opazo, C.1
Huang, X.2
Cherny, R.A.3
Moir, R.D.4
Roher, A.E.5
White, A.R.6
Cappai, R.7
Masters, C.L.8
Tanzi, R.E.9
Inestrosa, N.C.10
-
8
-
-
9144235443
-
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta
-
Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, et al.: Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry 2004, 43:560-568.
-
(2004)
Biochemistry
, vol.43
, pp. 560-568
-
-
Atwood, C.S.1
Perry, G.2
Zeng, H.3
Kato, Y.4
Jones, W.D.5
Ling, K.Q.6
Huang, X.7
Moir, R.D.8
Wang, D.9
Sayre, L.M.10
-
9
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
Curtain CC, Ali F, Volitakis I, Cherny RA, Norton RS, Beyreuther K, Barrow CJ, Masters CL, Bush AI, Barnham KJ: Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits. J Biol Chem 2001, 276:20466-20473.
-
(2001)
J Biol Chem
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
Cherny, R.A.4
Norton, R.S.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Bush, A.I.9
Barnham, K.J.10
-
10
-
-
0035805163
-
Nanoscale biogenic iron oxides and neurodegenerative disease
-
Dobson J: Nanoscale biogenic iron oxides and neurodegenerative disease. FEBS Lett 2001, 496:1-5.
-
(2001)
FEBS Lett
, vol.496
, pp. 1-5
-
-
Dobson, J.1
-
11
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA: RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci 1999, 19:1959-1964.
-
(1999)
J Neurosci
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
12
-
-
8544257019
-
Heme oxygenase expression in human central nervous system disorders
-
Schipper HM: Heme oxygenase expression in human central nervous system disorders. Free Radic Biol Med 2004, 37:1995-2011.
-
(2004)
Free Radic Biol Med
, vol.37
, pp. 1995-2011
-
-
Schipper, H.M.1
-
13
-
-
18744374615
-
Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
-
Perry G, Nunomura A, Hirai K, Zhu X, Prez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM: Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med 2002, 33:1475-1479.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1475-1479
-
-
Perry, G.1
Nunomura, A.2
Hirai, K.3
Zhu, X.4
Prez, M.5
Avila, J.6
Castellani, R.J.7
Atwood, C.S.8
Aliev, G.9
Sayre, L.M.10
-
14
-
-
0042591280
-
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
-
Rinaldi P, Polidori MC, Metastasio A, Mariani E, Mattioli P, Cherubini A, Catani M, Cecchetti R, Senin U, Mecocci P, et al.: Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease. Neurobiol Aging 2003, 24:915-919.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 915-919
-
-
Rinaldi, P.1
Polidori, M.C.2
Metastasio, A.3
Mariani, E.4
Mattioli, P.5
Cherubini, A.6
Catani, M.7
Cecchetti, R.8
Senin, U.9
Mecocci, P.10
-
15
-
-
0035425880
-
Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease
-
Kontush A, Mann U, Arlt S, Ujeyl A, Luhrs C, Muller-Thomsen T, Beisiegel U: Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Radic Biol Med 2001, 31:345-354.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 345-354
-
-
Kontush, A.1
Mann, U.2
Arlt, S.3
Ujeyl, A.4
Luhrs, C.5
Muller-Thomsen, T.6
Beisiegel, U.7
-
16
-
-
0037178573
-
Dietary intake of antioxidants and risk of Alzheimer disease
-
Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JCM, Breteler MMB: Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 2002, 287:3223-3229.
-
(2002)
JAMA
, vol.287
, pp. 3223-3229
-
-
Engelhart, M.J.1
Geerlings, M.I.2
Ruitenberg, A.3
Van Swieten, J.C.4
Hofman, A.5
Witteman, J.C.M.6
Breteler, M.M.B.7
-
17
-
-
0037178579
-
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study
-
Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA: Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. J Am Med Assoc 2002, 287:3230-3237.
-
(2002)
J Am Med Assoc
, vol.287
, pp. 3230-3237
-
-
Morris, M.C.1
Evans, D.A.2
Bienias, J.L.3
Tangney, C.C.4
Bennett, D.A.5
Aggarwal, N.6
Wilson, R.S.7
Scherr, P.A.8
-
18
-
-
0037320324
-
Antioxidant vitamin intake and risk of Alzheimer disease
-
Luchsinger JA, Tang MX, Shea S, Mayeux R: Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol 2003, 60:203-208.
-
(2003)
Arch Neurol
, vol.60
, pp. 203-208
-
-
Luchsinger, J.A.1
Tang, M.X.2
Shea, S.3
Mayeux, R.4
-
19
-
-
2342464079
-
Iron inhibits neurotoxicity induced by trace copper and biological reductants
-
White AR, Barnham KJ, Huang X, Voltakis I, Beyreuther K, Masters CL, Cherny RA, Bush AI, Cappai R: Iron inhibits neurotoxicity induced by trace copper and biological reductants. J Biol Inorg Chem 2004, 9:269-280.
-
(2004)
J Biol Inorg Chem
, vol.9
, pp. 269-280
-
-
White, A.R.1
Barnham, K.J.2
Huang, X.3
Voltakis, I.4
Beyreuther, K.5
Masters, C.L.6
Cherny, R.A.7
Bush, A.I.8
Cappai, R.9
-
20
-
-
0036860349
-
Metal complexing agents as therapies for Alzheimer's disease
-
Bush AI: Metal complexing agents as therapies for Alzheimer's disease. Neurobiol Aging 2002, 23:1031-1038.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 1031-1038
-
-
Bush, A.I.1
-
21
-
-
2942729775
-
Metals in our minds: Therapeutic implications for neurodegenerative disorders
-
Doraiswamy PM, Finefrock AE: Metals in our minds: therapeutic implications for neurodegenerative disorders. Lancet Neurol 2004, 3:431-434.
-
(2004)
Lancet Neurol
, vol.3
, pp. 431-434
-
-
Doraiswamy, P.M.1
Finefrock, A.E.2
-
22
-
-
0033855331
-
Chelation and intercalation: Complementary properties in a compound for the treatment of Alzheimer's disease
-
Cherny RA, Barnham KJ, Lynch T, Volitakis I, Li QX, McLean CA, Multhaup G, Beyreuther K, Tanzi RE, Masters CL, Bush AI: Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease. J Struct Biol 2000, 130:209-216.
-
(2000)
J Struct Biol
, vol.130
, pp. 209-216
-
-
Cherny, R.A.1
Barnham, K.J.2
Lynch, T.3
Volitakis, I.4
Li, Q.X.5
McLean, C.A.6
Multhaup, G.7
Beyreuther, K.8
Tanzi, R.E.9
Masters, C.L.10
Bush, A.I.11
-
23
-
-
9744219638
-
Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis
-
Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI: Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Exp Gerontol 2004, 39:1641-1649.
-
(2004)
Exp Gerontol
, vol.39
, pp. 1641-1649
-
-
Dedeoglu, A.1
Cormier, K.2
Payton, S.3
Tseitlin, K.A.4
Kremsky, J.N.5
Lai, L.6
Li, X.7
Moir, R.D.8
Tanzi, R.E.9
Bush, A.I.10
-
24
-
-
33847633861
-
Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases
-
in press
-
Zheng H, Weiner LM, Bar-Am O, Epsztejn S, Cabantchik ZI, Warshawsky A, Youdim MBH, Fridkin M: Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases. Bioorg Med Chem 2004 in press.
-
(2004)
Bioorg Med Chem
-
-
Zheng, H.1
Weiner, L.M.2
Bar-Am, O.3
Epsztejn, S.4
Cabantchik, Z.I.5
Warshawsky, A.6
Youdim, M.B.H.7
Fridkin, M.8
-
25
-
-
4644238758
-
The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice
-
Lee JY, Friedman JE, Angel I, Kozak A, Koh JY: The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice. Neurobiol Aging 2004, 25:1315-1321.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 1315-1321
-
-
Lee, J.Y.1
Friedman, J.E.2
Angel, I.3
Kozak, A.4
Koh, J.Y.5
-
26
-
-
0347419287
-
Novel peptoids for the detection and suppression of reactive oxygen and nitrogen species
-
Fisher AEO, Naughton DP: Novel peptoids for the detection and suppression of reactive oxygen and nitrogen species. Biochem Soc Trans 2003, 31:1302-1304.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1302-1304
-
-
Fisher, A.E.O.1
Naughton, D.P.2
-
27
-
-
0041762136
-
Catalase and superoxide dismutase mimics for the treatment of inflammatory diseases
-
Fisher AEO, Maxwell SC, Naughton DP: Catalase and superoxide dismutase mimics for the treatment of inflammatory diseases. Inorg Chem Comm 2003, 6:1205-1208.
-
(2003)
Inorg Chem Comm
, vol.6
, pp. 1205-1208
-
-
Fisher, A.E.O.1
Maxwell, S.C.2
Naughton, D.P.3
-
29
-
-
4444334224
-
Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG
-
Fisher AEO, Hague TA, Clarke CL, Naughton DP: Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG. Biochem Biophys Res Comm 2004, 323:163-167.
-
(2004)
Biochem Biophys Res Comm
, vol.323
, pp. 163-167
-
-
Fisher, A.E.O.1
Hague, T.A.2
Clarke, C.L.3
Naughton, D.P.4
|