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Volumn 85, Issue 3, 2005, Pages 194-202

Peroxisome proliferator-activated receptors and their relevance to dermatology

Author keywords

PPARs; Psoriasis; Thiazolidinediones; Transcription factors; Wound healing

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 15 HYDROXYICOSATETRAENOIC ACID; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 8 HYDROXYARACHIDONIC ACID; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ADENYLATE CYCLASE; ANGIOGENESIS INHIBITOR; ARACHIDONIC ACID; CARRIER PROTEIN; CELL NUCLEUS RECEPTOR; CLOBETASOL; CLOFIBRATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; ESTROGEN; FATTY ACID TRANSPORTER; GAMMA INTERFERON; GELATINASE B; GLUCOCORTICOID; HEAT SHOCK PROTEIN 72; HEAT SHOCK PROTEIN 90; HYDROGEN PEROXIDE; I KAPPA B; ICOSANOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; INVOLUCRIN; JANUS KINASE; KERATIN; LEUKOTRIENE B4; LINOLEIC ACID; LIPOPROTEIN LIPASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; LORICRIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; OXAZOLONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PIOGLITAZONE; PIRINIXIC ACID; PROTEIN KINASE C; RANTES; RECEPTOR BLOCKING AGENT; RETINOID; RETINOID X RECEPTOR; ROSIGLITAZONE; STAT1 PROTEIN; T LYMPHOCYTE RECEPTOR; TESTOSTERONE; THYROID HORMONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR RELA; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 18844420808     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.1080/00015550510030104     Document Type: Review
Times cited : (34)

References (61)
  • 1
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990; 347: 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 2
    • 0036510359 scopus 로고    scopus 로고
    • Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent
    • Jones DC, Ding X, Daynes RA. Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent. J Biol Chem 2002; 277: 6838-6845.
    • (2002) J Biol Chem , vol.277 , pp. 6838-6845
    • Jones, D.C.1    Ding, X.2    Daynes, R.A.3
  • 3
    • 17744392617 scopus 로고    scopus 로고
    • Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid
    • Westergaard M, Henningsen J, Svendsen ML, Johansen C, Jensen UB, Schroder HD, et al. Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol 2001; 116: 702-712.
    • (2001) J Invest Dermatol , vol.116 , pp. 702-712
    • Westergaard, M.1    Henningsen, J.2    Svendsen, M.L.3    Johansen, C.4    Jensen, U.B.5    Schroder, H.D.6
  • 4
    • 10744228768 scopus 로고    scopus 로고
    • Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin
    • Westergaard M, Henningsen J, Johansen C, Rasmussen S, Svendsen ML, Jensen UB, et al. Expression and localization of peroxisome proliferator-activated receptors and nuclear factor kappaB in normal and lesional psoriatic skin. J Invest Dermatol 2003; 121: 1104-1117.
    • (2003) J Invest Dermatol , vol.121 , pp. 1104-1117
    • Westergaard, M.1    Henningsen, J.2    Johansen, C.3    Rasmussen, S.4    Svendsen, M.L.5    Jensen, U.B.6
  • 5
    • 0037106543 scopus 로고    scopus 로고
    • Genomic organization of the mouse peroxisome proliferator-activated receptor beta/delta gene: Alternative promoter usage and splicing yield transcripts exhibiting differential translational efficiency
    • Larsen LK, Amri EZ, Mandrup S, Pacot C, Kristiansen K. Genomic organization of the mouse peroxisome proliferator-activated receptor beta/delta gene: alternative promoter usage and splicing yield transcripts exhibiting differential translational efficiency. Biochem J 2002; 366: 767-775.
    • (2002) Biochem J , vol.366 , pp. 767-775
    • Larsen, L.K.1    Amri, E.Z.2    Mandrup, S.3    Pacot, C.4    Kristiansen, K.5
  • 6
    • 0035921419 scopus 로고    scopus 로고
    • Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta mutant mice
    • Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, et al. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) alpha and PPARbeta mutant mice. J Cell Biol 2001; 154: 799-814.
    • (2001) J Cell Biol , vol.154 , pp. 799-814
    • Michalik, L.1    Desvergne, B.2    Tan, N.S.3    Basu-Modak, S.4    Escher, P.5    Rieusset, J.6
  • 7
    • 0043165094 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: What is possible?
    • Tan NS, Michalik L, Desvergne B, Wahli W. Peroxisome proliferator- activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible? Am J Clin Dermatol 2003; 4: 523-530.
    • (2003) Am J Clin Dermatol , vol.4 , pp. 523-530
    • Tan, N.S.1    Michalik, L.2    Desvergne, B.3    Wahli, W.4
  • 8
    • 0030590074 scopus 로고    scopus 로고
    • Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2
    • Elbrecht A, Chen Y, Cullinan CA, Hayes N, Leibowitz M, Moller DE, et al. Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem Biophys Res Commun 1996; 224: 431-437.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 431-437
    • Elbrecht, A.1    Chen, Y.2    Cullinan, C.A.3    Hayes, N.4    Leibowitz, M.5    Moller, D.E.6
  • 9
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator activated receptor gamma cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene ME, Blumberg B, McBride OW, Yi HF, Kronquist K, Kwan K, et al. Isolation of the human peroxisome proliferator activated receptor gamma cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expr 1995; 4: 281-299.
    • (1995) Gene Expr , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3    Yi, H.F.4    Kronquist, K.5    Kwan, K.6
  • 10
    • 0038116167 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor gamma and its ligands in the control of immune responses
    • Nencioni A, Wesselborg S, Brossart P. Role of peroxisome proliferator-activated receptor gamma and its ligands in the control of immune responses. Crit Rev Immunol 2003; 23: 1-13.
    • (2003) Crit Rev Immunol , vol.23 , pp. 1-13
    • Nencioni, A.1    Wesselborg, S.2    Brossart, P.3
  • 11
    • 0042334918 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes
    • Chen W, Yang CC, Sheu HM, Seltmann H, Zouboulis CC. Expression of peroxisome proliferator-activated receptor and CCAAT/enhancer binding protein transcription factors in cultured human sebocytes. J Invest Dermatol 2003; 121:441-447.
    • (2003) J Invest Dermatol , vol.121 , pp. 441-447
    • Chen, W.1    Yang, C.C.2    Sheu, H.M.3    Seltmann, H.4    Zouboulis, C.C.5
  • 12
    • 9144237419 scopus 로고    scopus 로고
    • Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes
    • Bhagavathula N, Nerusu KC, Lal A, Ellis CN, Chittiboyina A, Avery MA, et al. Rosiglitazone inhibits proliferation, motility, and matrix metalloproteinase production in keratinocytes. J Invest Dermatol 2004; 122: 130-139.
    • (2004) J Invest Dermatol , vol.122 , pp. 130-139
    • Bhagavathula, N.1    Nerusu, K.C.2    Lal, A.3    Ellis, C.N.4    Chittiboyina, A.5    Avery, M.A.6
  • 13
    • 3242690411 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation
    • Mao-Qiang M, Fowler AJ, Schmuth M, Lau P, Chang S, Brown BE, et al. Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. J Invest Dermatol 2004; 123: 305-312.
    • (2004) J Invest Dermatol , vol.123 , pp. 305-312
    • Mao-Qiang, M.1    Fowler, A.J.2    Schmuth, M.3    Lau, P.4    Chang, S.5    Brown, B.E.6
  • 14
    • 0036681640 scopus 로고    scopus 로고
    • Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma
    • Nencioni A, Grunebach F, Zobywlaski A, Denzlinger C, Brugger W, Brossart P. Dendritic cell immunogenicity is regulated by peroxisome proliferator- activated receptor gamma. J Immunol 2002; 169: 1228-1235.
    • (2002) J Immunol , vol.169 , pp. 1228-1235
    • Nencioni, A.1    Grunebach, F.2    Zobywlaski, A.3    Denzlinger, C.4    Brugger, W.5    Brossart, P.6
  • 15
    • 0035062387 scopus 로고    scopus 로고
    • The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis
    • Harris SG, Phipps RP. The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. Eur J Immunol 2001; 31: 1098-1105.
    • (2001) Eur J Immunol , vol.31 , pp. 1098-1105
    • Harris, S.G.1    Phipps, R.P.2
  • 16
    • 0041887308 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Regulation of transcriptional activities and roles in inflammation
    • Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C. Peroxisome proliferator-activated receptors: regulation of transcriptional activities and roles in inflammation. J Steroid Biochem Mol Biol 2003; 85: 267-273.
    • (2003) J Steroid Biochem Mol Biol , vol.85 , pp. 267-273
    • Blanquart, C.1    Barbier, O.2    Fruchart, J.C.3    Staels, B.4    Glineur, C.5
  • 17
    • 0028309738 scopus 로고
    • Association of peroxisome proliferator-activated receptor and Hsp72
    • Huang Q, Alvares K, Chu R, Bradfield CA, Reddy JK. Association of peroxisome proliferator-activated receptor and Hsp72. J Biol Chem 1994; 269: 8493-8497.
    • (1994) J Biol Chem , vol.269 , pp. 8493-8497
    • Huang, Q.1    Alvares, K.2    Chu, R.3    Bradfield, C.A.4    Reddy, J.K.5
  • 18
    • 0042318859 scopus 로고    scopus 로고
    • Heat shock protein-90 (Hsp90) acts as a represser of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity
    • Sumanasekera WK, Tien ES, Davis JW, Turpey R, Perdew GH, Vanden Heuvel JP. Heat shock protein-90 (Hsp90) acts as a represser of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity. Biochemistry 2003; 42: 10726-10735.
    • (2003) Biochemistry , vol.42 , pp. 10726-10735
    • Sumanasekera, W.K.1    Tien, E.S.2    Davis, J.W.3    Turpey, R.4    Perdew, G.H.5    Vanden Heuvel, J.P.6
  • 19
    • 0242526756 scopus 로고    scopus 로고
    • Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta
    • Chen F, Wang M, O'Connor JP, He M, Tripathi T, Harrison LE. Phosphorylation of PPARgamma via active ERK1/2 leads to its physical association with p65 and inhibition of NF-kappabeta. J Cell Biochem 2003; 90: 732-744.
    • (2003) J Cell Biochem , vol.90 , pp. 732-744
    • Chen, F.1    Wang, M.2    O'Connor, J.P.3    He, M.4    Tripathi, T.5    Harrison, L.E.6
  • 20
    • 84965814821 scopus 로고
    • Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment
    • Verma AK. Inhibition of both stage I and stage II mouse skin tumour promotion by retinoic acid and the dependence of inhibition of tumor promotion on the duration of retinoic acid treatment. Cancer Res 1987; 47: 5097-5101.
    • (1987) Cancer Res , vol.47 , pp. 5097-5101
    • Verma, A.K.1
  • 21
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists
    • Grommes C, Landreth GE, Heneka MT. Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. Lancet Oncol 2004; 5: 419-429.
    • (2004) Lancet Oncol , vol.5 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 22
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • Elstner E, Muller C, Koshizuka K, Williamson EA, Park D, Asou H, et al. Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci U S A 1998; 95: 8806-8811.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8806-8811
    • Elstner, E.1    Muller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6
  • 23
    • 0031671246 scopus 로고    scopus 로고
    • Differentiation and reversal of malignant changes in colon cancer through PPARgamma
    • Sarraf P, Mueller E, Jones D, King FJ, DeAngelo DJ, Partridge JB, et al. Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nat Med 1998; 4: 1046-1052.
    • (1998) Nat Med , vol.4 , pp. 1046-1052
    • Sarraf, P.1    Mueller, E.2    Jones, D.3    King, F.J.4    DeAngelo, D.J.5    Partridge, J.B.6
  • 24
    • 0036730017 scopus 로고    scopus 로고
    • A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer
    • Kulke MH, Demetri GD, Sharpless NE, Ryan DP, Shivdasani R, Clark JS, et al. A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J 2002; 8: 395-399.
    • (2002) Cancer J , vol.8 , pp. 395-399
    • Kulke, M.H.1    Demetri, G.D.2    Sharpless, N.E.3    Ryan, D.P.4    Shivdasani, R.5    Clark, J.S.6
  • 25
    • 0037899628 scopus 로고    scopus 로고
    • Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: A phase II study
    • Burstein HJ, Demetri GD, Mueller E, Sarraf P, Spiegelman BM, Winer EP. Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase II study. Breast Cancer Res Treat 2003; 79: 391-397.
    • (2003) Breast Cancer Res Treat , vol.79 , pp. 391-397
    • Burstein, H.J.1    Demetri, G.D.2    Mueller, E.3    Sarraf, P.4    Spiegelman, B.M.5    Winer, E.P.6
  • 26
    • 0025223041 scopus 로고
    • Multi-stage program of differentiation in human epidermal keratinocytes: Regulation by retinoids
    • Jetten AM. Multi-stage program of differentiation in human epidermal keratinocytes: regulation by retinoids. J Invest Dermatol 1990; 95: 44S-46S.
    • (1990) J Invest Dermatol , vol.95
    • Jetten, A.M.1
  • 27
    • 0040952982 scopus 로고    scopus 로고
    • Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha
    • Hanley K, Komuves LG, Ng DC, Schoonjans K, He SS, Lau P, et al. Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha. J Biol Chem 2000; 275: 11484-11491.
    • (2000) J Biol Chem , vol.275 , pp. 11484-11491
    • Hanley, K.1    Komuves, L.G.2    Ng, D.C.3    Schoonjans, K.4    He, S.S.5    Lau, P.6
  • 29
    • 0033832034 scopus 로고    scopus 로고
    • Keratinocyte differentiation in hyperproliferative epidermis: Topical application of PPARalpha activators restores tissue homeostasis
    • Komuves LG, Hanley K, Man MQ, Elias PM, Williams ML, Feingold KR. Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis. J Invest Dermatol 2000; 115: 361-367.
    • (2000) J Invest Dermatol , vol.115 , pp. 361-367
    • Komuves, L.G.1    Hanley, K.2    Man, M.Q.3    Elias, P.M.4    Williams, M.L.5    Feingold, K.R.6
  • 30
    • 2342579597 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes
    • Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, et al. Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. J Invest Dermatol 2004; 122: 971-983.
    • (2004) J Invest Dermatol , vol.122 , pp. 971-983
    • Schmuth, M.1    Haqq, C.M.2    Cairns, W.J.3    Holder, J.C.4    Dorsam, S.5    Chang, S.6
  • 31
    • 0033625677 scopus 로고    scopus 로고
    • Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
    • Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, et al. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol Cell Biol 2000; 20: 5119-5128.
    • (2000) Mol Cell Biol , vol.20 , pp. 5119-5128
    • Peters, J.M.1    Lee, S.S.2    Li, W.3    Ward, J.M.4    Gavrilova, O.5    Everett, C.6
  • 32
    • 0033904659 scopus 로고    scopus 로고
    • 8S-lipoxygenase products activate peroxisome proliferator-activated receptor alpha and induce differentiation in murine keratinocytes
    • Muga SJ, Thuillier P, Pavone A, Rundhaug JE, Boeglin WE, Jisaka M, et al. 8S-lipoxygenase products activate peroxisome proliferator-activated receptor alpha and induce differentiation in murine keratinocytes. Cell Growth Differ 2000; 11: 447-454.
    • (2000) Cell Growth Differ , vol.11 , pp. 447-454
    • Muga, S.J.1    Thuillier, P.2    Pavone, A.3    Rundhaug, J.E.4    Boeglin, W.E.5    Jisaka, M.6
  • 33
    • 0030835838 scopus 로고    scopus 로고
    • Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier
    • Hanley K, Jiang Y, Crumrine D, Bass NM, Appel R, Elias PM, et al. Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier. J Clin Invest 1997; 100: 705-712.
    • (1997) J Clin Invest , vol.100 , pp. 705-712
    • Hanley, K.1    Jiang, Y.2    Crumrine, D.3    Bass, N.M.4    Appel, R.5    Elias, P.M.6
  • 34
    • 0034004910 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha enhances lipid metabolism in a skin equivalent model
    • Rivier M, Castiel I, Safonova I, Ailhaud G, Michel S. Peroxisome proliferator-activated receptor-alpha enhances lipid metabolism in a skin equivalent model. J Invest Dermatol 2000; 114: 681-687.
    • (2000) J Invest Dermatol , vol.114 , pp. 681-687
    • Rivier, M.1    Castiel, I.2    Safonova, I.3    Ailhaud, G.4    Michel, S.5
  • 35
    • 0035893364 scopus 로고    scopus 로고
    • Critical roles of PPAR beta/delta in keratinocyte response to inflammation
    • Tan NS, Michalik L, Noy N, Yasmin R, Pacot C, Heim M, et al. Critical roles of PPAR beta/delta in keratinocyte response to inflammation. Genes Dev 2001; 15: 3263-3277.
    • (2001) Genes Dev , vol.15 , pp. 3263-3277
    • Tan, N.S.1    Michalik, L.2    Noy, N.3    Yasmin, R.4    Pacot, C.5    Heim, M.6
  • 36
    • 1442308951 scopus 로고    scopus 로고
    • Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator- activated receptor beta) in skin wound healing
    • Tan NS, Michalik L, Di Poi N, Desvergne B, Wahli W. Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing. Biochem Soc Trans 2004; 32: 97-102.
    • (2004) Biochem Soc Trans , vol.32 , pp. 97-102
    • Tan, N.S.1    Michalik, L.2    Di Poi, N.3    Desvergne, B.4    Wahli, W.5
  • 37
    • 0032484123 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging
    • Poynter ME, Daynes RA. Peroxisome proliferator-activated receptor alpha activation modulates cellular redox status, represses nuclear factor-kappaB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 1998; 273: 32833-32841.
    • (1998) J Biol Chem , vol.273 , pp. 32833-32841
    • Poynter, M.E.1    Daynes, R.A.2
  • 38
    • 0036153739 scopus 로고    scopus 로고
    • Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models
    • Sheu MY, Fowler AJ, Kao J, Schmuth M, Schoonjans K, Auwerx J, et al. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. J Invest Dermatol 2002; 118: 94-101.
    • (2002) J Invest Dermatol , vol.118 , pp. 94-101
    • Sheu, M.Y.1    Fowler, A.J.2    Kao, J.3    Schmuth, M.4    Schoonjans, K.5    Auwerx, J.6
  • 39
    • 0035677813 scopus 로고    scopus 로고
    • Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light-induced inflammation
    • Kippenberger S, Loitsch SM, Grundmann-Kollmann M, Simon S, Dang TA, Hardt-Weinelt K, et al. Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light-induced inflammation. J Invest Dermatol 2001; 117: 1430-1436.
    • (2001) J Invest Dermatol , vol.117 , pp. 1430-1436
    • Kippenberger, S.1    Loitsch, S.M.2    Grundmann-Kollmann, M.3    Simon, S.4    Dang, T.A.5    Hardt-Weinelt, K.6
  • 40
    • 0037023635 scopus 로고    scopus 로고
    • PPAR activators as antiinflammatory mediators in human T lymphocytes: Implications for atherosclerosis and transplantation-associated arteriosclerosis
    • Marx N, Kehrle B, Kohlhammer K, Grub M, Koenig W, Hombach V, et al. PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis. Circ Res 2002; 90: 703-710.
    • (2002) Circ Res , vol.90 , pp. 703-710
    • Marx, N.1    Kehrle, B.2    Kohlhammer, K.3    Grub, M.4    Koenig, W.5    Hombach, V.6
  • 41
    • 0033594810 scopus 로고    scopus 로고
    • PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
    • Marx N, Sukhova GK, Collins T, Libby P, Plutzky J. PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 1999; 99: 3125-3131.
    • (1999) Circulation , vol.99 , pp. 3125-3131
    • Marx, N.1    Sukhova, G.K.2    Collins, T.3    Libby, P.4    Plutzky, J.5
  • 42
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri V, Wu HD, Willerson JT, Yeh ET. Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 2000; 101: 235-238.
    • (2000) Circulation , vol.101 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.4
  • 43
    • 0033520304 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway
    • Delerive P, Martin-Nizard F, Chinetti G, Trottein F, Fruchart JC, Najib J, et al. Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway. Circ Res 1999; 85: 394-402.
    • (1999) Circ Res , vol.85 , pp. 394-402
    • Delerive, P.1    Martin-Nizard, F.2    Chinetti, G.3    Trottein, F.4    Fruchart, J.C.5    Najib, J.6
  • 44
    • 0034711185 scopus 로고    scopus 로고
    • Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators
    • Delerive P, Gervois P, Fruchart JC, Staels B. Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators. J Biol Chem 2000; 275: 36703-36707.
    • (2000) J Biol Chem , vol.275 , pp. 36703-36707
    • Delerive, P.1    Gervois, P.2    Fruchart, J.C.3    Staels, B.4
  • 45
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • Delerive P, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 2001; 169: 453-459.
    • (2001) J Endocrinol , vol.169 , pp. 453-459
    • Delerive, P.1    Fruchart, J.C.2    Staels, B.3
  • 46
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
    • Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, et al. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 1999; 274: 32048-32054.
    • (1999) J Biol Chem , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3    Vanden Berghe, W.4    Peters, J.M.5    Gonzalez, F.J.6
  • 47
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 48
    • 0037231474 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells
    • Calnek DS, Mazzella L, Roser S, Roman J, Hart CM. Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23: 52-57.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 52-57
    • Calnek, D.S.1    Mazzella, L.2    Roser, S.3    Roman, J.4    Hart, C.M.5
  • 49
    • 0032891042 scopus 로고    scopus 로고
    • Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells
    • Hattori Y, Hattori S, Kasai K. Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells. Hypertension 1999; 33: 943-948.
    • (1999) Hypertension , vol.33 , pp. 943-948
    • Hattori, Y.1    Hattori, S.2    Kasai, K.3
  • 50
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391: 82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 51
    • 0034585795 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor-gamma increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages
    • Jozkowicz A, Dulak J, Piatkowska E, Placha W, Dembinska-Kiec A. Ligands of peroxisome proliferator-activated receptor-gamma increase the generation of vascular endothelial growth factor in vascular smooth muscle cells and in macrophages. Acta Biochim Pol 2000; 47: 1147-1157.
    • (2000) Acta Biochim Pol , vol.47 , pp. 1147-1157
    • Jozkowicz, A.1    Dulak, J.2    Piatkowska, E.3    Placha, W.4    Dembinska-Kiec, A.5
  • 52
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001; 7: 48-52.
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 53
    • 0034121698 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
    • Li M, Pascual G, Glass CK. Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol Cell Biol 2000; 20: 4699-4707.
    • (2000) Mol Cell Biol , vol.20 , pp. 4699-4707
    • Li, M.1    Pascual, G.2    Glass, C.K.3
  • 54
    • 0001297403 scopus 로고    scopus 로고
    • Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT
    • Yang XY, Wang LH, Chen T, Hodge DR, Resau JH, DaSilva L, et al. Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT. J Biol Chem 2000; 275: 4541-4544.
    • (2000) J Biol Chem , vol.275 , pp. 4541-4544
    • Yang, X.Y.1    Wang, L.H.2    Chen, T.3    Hodge, D.R.4    Resau, J.H.5    DaSilva, L.6
  • 55
    • 0034685660 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonists increase vascular endothelial growth factor expression in human vascular smooth muscle cells
    • Yamakawa K, Hosoi M, Koyama H, Tanaka S, Fukumoto S, Morii H, et al. Peroxisome proliferator-activated receptor-gamma agonists increase vascular endothelial growth factor expression in human vascular smooth muscle cells. Biochem Biophys Res Commun 2000; 271: 571-574.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 571-574
    • Yamakawa, K.1    Hosoi, M.2    Koyama, H.3    Tanaka, S.4    Fukumoto, S.5    Morii, H.6
  • 56
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • Xin X, Yang S, Kowalski J, Gerritsen ME. Peroxisome proliferator- activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem 1999; 274: 9116-9121.
    • (1999) J Biol Chem , vol.274 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 58
    • 0034030527 scopus 로고    scopus 로고
    • Troglitazone improves psoriasis and normalizes models of proliferative skin disease: Ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation
    • Ellis CN, Varani J, Fisher GJ, Zeigler ME, Pershadsingh HA, Benson SC, et al. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Arch Dermatol 2000; 136: 609-616.
    • (2000) Arch Dermatol , vol.136 , pp. 609-616
    • Ellis, C.N.1    Varani, J.2    Fisher, G.J.3    Zeigler, M.E.4    Pershadsingh, H.A.5    Benson, S.C.6
  • 59
    • 13244286538 scopus 로고    scopus 로고
    • Pioglitazone: A promising therapy for psoriasis
    • Robertshaw H, Friedmann PS. Pioglitazone: a promising therapy for psoriasis. Br J Dermatol 2005; 15: 189-91.
    • (2005) Br J Dermatol , vol.15 , pp. 189-191
    • Robertshaw, H.1    Friedmann, P.S.2
  • 60
    • 0037250963 scopus 로고    scopus 로고
    • Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis, a pilot study
    • Kuenzli S, Saurat JH. Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis, a pilot study. Dermatology 2003; 206: 252-256.
    • (2003) Dermatology , vol.206 , pp. 252-256
    • Kuenzli, S.1    Saurat, J.H.2
  • 61
    • 3042667047 scopus 로고    scopus 로고
    • Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis
    • Mossner R, Kaiser R, Matern P, Kruger U, Westphal GA, Brockmoller J, et al. Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis. Arch Dermatol Res 2004; 296: 1-5.
    • (2004) Arch Dermatol Res , vol.296 , pp. 1-5
    • Mossner, R.1    Kaiser, R.2    Matern, P.3    Kruger, U.4    Westphal, G.A.5    Brockmoller, J.6


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