Solid-supported lipid membranes as a tool for determination of membrane affinity: High-throughput screening of a physicochemical parameter

Journal of Pharmaceutical Sciences

Volumn 90, Issue 5, 2001, Pages 599-606

  Loidl Stahlhofen, Angelika ^a   Eckert, Annett ^a   Hartmann, Thorsten ^a   Schöttner, Matthias ^a  

^a Nimbus GmbH   (Germany)

Author keywords

Drug design; High throughput; Lipid water partitioning; Lipophilicity; Membrane affinity; Solid supported lipid membranes

Indexed keywords

ACEBUTOLOL; ACICLOVIR; ACID; BASE; BENZOCAINE; CARBAMAZEPINE; CHLORPROMAZINE; DICLOFENAC; IBUPROFEN; INDOMETACIN; KETOPROFEN; LIDOCAINE; LIPID; NIFEDIPINE; OCTANOL; ORGANIC COMPOUND; OXPRENOLOL; PIROXICAM; PROCAINE; PROPRANOLOL; TETRACAINE; VALERIC ACID DERIVATIVE; WARFARIN; WATER;

ARTICLE; BINDING AFFINITY; CENTRIFUGATION; DRUG DESIGN; FILTRATION; LIPID MEMBRANE; LIPOPHILICITY; PARTITION COEFFICIENT; PH; PHYSICAL CHEMISTRY;

EID: 0035035820     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6017(200105)90:5<599::AID-JPS1016>3.0.CO;2-N     Document Type: Article

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