Ionization constants and distribution coefficients of phenothiazines and calcium channel antagonists determined by a pH-metric method and correlation with calculated partition coefficients

Journal of Pharmaceutical Sciences

Volumn 88, Issue 1, 1999, Pages 89-95

  Franke, Ulrich ^a   Munk, Angela ^a   Wiese, Michael ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; CALCIUM CHANNEL BLOCKING AGENT; CHLORPROMAZINE; FENDILINE; GALLOPAMIL; LEVOMEPROMAZINE; NICARDIPINE; PERPHENAZINE; PHENOTHIAZINE DERIVATIVE; PROCHLORPERAZINE; PROMAZINE; PROMETHAZINE; THIETHYLPERAZINE; THIORIDAZINE; TRIFLUOPERAZINE; TRIFLUPROMAZINE; VERAPAMIL;

ARTICLE; DRUG BINDING; DRUG DISTRIBUTION; DRUG STRUCTURE; IONIC STRENGTH; IONIZATION; LIPOPHILICITY; MEMBRANE BINDING; PARTITION COEFFICIENT; PH MEASUREMENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

EID: 0032903082     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js980206m     Document Type: Article

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