Lipophilicity behaviour of the zwitterionic antihistamine cetirizine in phosphatidylcholine liposomes/water systems

Pharmaceutical Research

Volumn 18, Issue 5, 2001, Pages 694-701

  Van Balen, Georgette Plemper ^a   Caron, Giulia ^a,b   Ermondi, Giuseppe ^c   Pagliara, Alessandra ^a   Grandi, Teresa ^a   Bouchard, Géraldine ^a   Fruttero, Roberta ^b   Carrupt, Pierre Alain ^a   Testa, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Cetirizine; Distribution profiles; Equilibrium dialysis, potentiometry; Lipophilicity; NMR; Phosphatidylcholine liposomes

Indexed keywords

AMPHOLYTE; ANTIHISTAMINIC AGENT; CETIRIZINE; LIPOSOME; PHOSPHATIDYLCHOLINE;

ARTICLE; DISTRIBUTION VOLUME; DRUG SYNTHESIS; LIPOPHILICITY; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SUSPENSION;

CETIRIZINE; CHEMISTRY, PHYSICAL; DIALYSIS; EMULSIONS; FLUORESCEINS; HISTAMINE H1 ANTAGONISTS; HYDROXYZINE; INDICATORS AND REAGENTS; LIPOSOMES; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHATIDYLCHOLINES; POTENTIOMETRY; TRIPROLIDINE; WATER;

EID: 0034955291     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011049830615     Document Type: Article

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