A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype

Genetics

Volumn 152, Issue 4, 1999, Pages 1631-1639

  Stowers, R Steven ^a   Schwarz, Thomas L ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SYNAPTOTAGMIN; SYNTAXIN;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; DROSOPHILA; ELECTRORETINOGRAM; EMBRYO; EYE DEVELOPMENT; GENETIC ANALYSIS; GENOTYPE; MITOSIS; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SYNAPTIC TRANSMISSION;

ANIMALS; CALCIUM-BINDING PROTEINS; CELL LINEAGE; CHROMOSOMES; CLONE CELLS; CROSSES, GENETIC; DROSOPHILA MELANOGASTER; ELECTRORETINOGRAPHY; EYE; GENES, LETHAL; GENETIC TECHNIQUES; GENOTYPE; INSECT PROTEINS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, SCANNING; MOSAICISM; NERVE TISSUE PROTEINS; QA-SNARE PROTEINS; RECOMBINATION, GENETIC; SYNAPTOTAGMINS;

ANIMALIA; HEXAPODA;

EID: 0345192349     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. BENZER, S., 1967 Behavioral mutants of Drosophila isolated by countercurrent distribution. Proc. Natl. Acad. Sci. USA 58: 1112-1119.
2. BRAND, A. H., and N. PERRIMON, 1993 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
3. BURGESS, R. W., D. L. DEITCHER and T. L. SCHWARZ, 1997 The synaptic protein syntaxin 1 is required for cellularization of Drosophila embryos. J. Cell Biol. 138: 861-875.
4. DIANTONIO, A., and T. L. SCHWARZ, 1994 The effect on synaptic physiology of synaptotagmin mutations in Drosophila. Neuron 12: 909-920.
5. DICKSON, B. J., A. VAN DER STRATEN, M. DOMINGUEZ and E. HAFEN, 1996 Mutations modulating Raf signaling in Drosophila eye development. Genetics 142: 163-171.
6. DUFFY, J. B., D. A. HARRISON and N. PERRIMON, 1998 Identifying loci required for follicular patterning using directed mosaics. Development 125: 2263-2271.
7. ENGELS, W. R., 1996 P-elements in Drosophila, pp. 103-123 in Transposable Elements, edited by H. SAEDLER and A. GIERL. Springer, Berlin.
8. FREEMAN, M., B. E. KIMMEL and G. M. RUBIN, 1992 Identifying targets of the rough homeobox gene of Drosophila: evidence that rhomboid functions in eye development. Development 116: 335-346.
9. GITSCHIER, J., G. R. STRICHARTZ and L. M. HALL, 1980 Saxitoxin binding to sodium channels in head extracts from wild-type and tetrodotoxin-sensitive strains of Drosophila melanogaster. Biochim. Biophys. Acta 595: 291-303.
10. GOLIC, K. G., and S. LINDQUIST, 1989 The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59: 499-509.
11. GRETHER, M. E., J. M. ABRAMS, J. AGAPITE, K. WHITE and H. STELLER, 1995 The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9: 1694-1708.
12. HARRIS, W. A., W. S. STARK and J. A. WALKER, 1976 Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster. J. Physiol. 256: 415-439.
13. HAY, B. A., T. WOLFF and G. M. RUBIN, 1994 Expression of baculovirus P35 prevents cell death in Drosophila. Development 120: 2121-2129.
14. HAZELETT, D. J., M. BOUROUIS, U. WALLDORF and J. E. TREISMAN, 1998 decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc. Development 125: 3741-3751.
15. HEISENBERG, M., 1971 Isolation of mutants lacking the optomotor response. Dros. Inf. Serv. 46: 68.
16. KARIM, F. D., H. C. CHANG, M. THERRIEN, D. A. WASSARMAN, T. LAVERTY et al., 1996 A screen for genes that function downstream of Ras1 during Drosophila eye development. Genetics 143: 315-329.
17. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
18. NEUFELD, T. P., A. H. TANG and G. M. RUBIN, 1998 A genetic screen to identify components of the sina signaling pathway in Drosophila eye development. Genetics 148: 277-286.
19. ONDEK, B., R. W. HARDY, E. K. BAKER, M. A. STAMNES, B. H. SHIEH et al., 1992 Genetic dissection of cyclophilin function. Saturation mutagenesis of the Drosophila cyclophilin homolog ninaA. J. Biol. Chem. 267: 16460-16466.
20. PAK, W. L., 1975 Mutations affecting the vision of Drosophila, pp. 703-733 in Handbook of Genetics, Vol. 3, edited by R. C. KING. Plenum, New York.
21. PAK, W. L. 1991 Molecular genetic studies of photoreceptor function using Drosophila mutants. Prog. Clin. Biol. Res. 362: 1-32.
22. PAK, W. L., 1995 Drosophila in vision research. The Friedenwald Lecture. Invest. Ophthalmol. Visual Sci. 36: 2340-2357.
23. PAK, W. L., J. GROSSFIELD and N. V. WHITE, 1969 Nonphototactic mutants in a study of vision of Drosophila. Nature 222: 351-354.
24. PIGNONI, F., B. HU and S. L. ZIPURSKY, 1997 Identification of genes required for Drosophila eye development using a phenotypic enhancer-trap. Proc. Natl. Acad. Sci. USA 94: 9220-9225.
25. QUIRING, R., U. WALLDORF, U. KLOTER and W. J. GEHRING, 1994 Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science 265: 785-789.
26. REINKE, R., and S. L. ZIPURSKY, 1988 Cell-cell interaction in the Drosophila retina: the bride of sevenless gene is required in photoreceptor cell R8 for R7 cell development. Cell 55: 321-330.
27. SCHULZE, K. L., and H. J. BELLEN, 1996 Drosophila syntaxin is required for cell viability and may function in membrane formation and stabilization. Genetics 144: 1713-1724.
28. SIMON, M. A., 1994 Signal transduction during the development of the Drosophila R7 photoreceptor. Dev. Biol. 166: 431-442.
29. SIMON, M. A., D. D. BOWTELL, G. S. DODSON, T. R. LAVERTY and G. M. RUBIN, 1991 Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. Cell 67: 701-716.
30. STEPHENSON, R. S., J. O'TOUSA, N. J. SCAVARDA, L. L. RANDALL and W. L. PAK, 1983 Drosophila mutants with reduced rhodopsin content. Symp. Soc. Exp. Biol. 36: 477-501.
31. THAKER, H. M., and D. R. KANKEL, 1992 Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster. Genetics 131: 883-894.
32. WOLFF, T., and D. READY, 1993 Pattern formation in the Drosophila retina, pp. 1277-1326 in The Development of Drosophila melanogaster, edited by M. BATE and A. ARIAS. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
33. XU, T., and G. M. RUBIN, 1993 Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117: 1223-1237.
34. ZIPURSKY, S. L., and G. M. RUBIN, 1994 Determination of neuronal cell fate: lessons from the R7 neuron of Drosophila. Annu. Rev. Neurosci. 17: 373-397.
35. ZUKER, C. S., 1996 The biology of vision of Drosophila. Proc. Natl. Acad. Sci. USA 93: 571-576.