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Volumn 172, Issue 8, 2004, Pages 4893-4901

CTLA-4 Blockage Increases Resistance to Infection with the Intracellular Protozoan Trypanosoma cruzi

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; NITRIC OXIDE; PARASITE ANTIGEN;

EID: 1842581712     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.8.4893     Document Type: Article
Times cited : (46)

References (58)
  • 1
    • 0035468745 scopus 로고    scopus 로고
    • Clinical and epidemiological aspects of Chagas disease
    • Prata, A. 2001. Clinical and epidemiological aspects of Chagas disease. Lancet Infect. Dis. 1-92.
    • (2001) Lancet Infect. Dis. , pp. 1-92
    • Prata, A.1
  • 2
    • 0030745157 scopus 로고    scopus 로고
    • Cell-mediated immunity in experimental Trypanosoma cruzi infection
    • DosReis, G. A. 1997. Cell-mediated immunity in experimental Trypanosoma cruzi infection. Parasitol. Today 13:335.
    • (1997) Parasitol. Today , vol.13 , pp. 335
    • DosReis, G.A.1
  • 3
    • 0029098304 scopus 로고
    • Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection
    • Abrahamsohn, I. A., R. L. Coffman. 1995. Cytokine and nitric oxide regulation of the immunosuppression in Trypanosoma cruzi infection. J. Immunol. 155: 3955.
    • (1995) J. Immunol. , vol.155 , pp. 3955
    • Abrahamsohn, I.A.1    Coffman, R.L.2
  • 4
    • 0031670153 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice
    • Martins, G. A., M. A. Cordoso, J. C. Aliberti, and J. S. Silva. 1998. Nitric oxide-induced apoptotic cell death in the acute phase of Trypanosoma cruzi infection in mice. Immunol. Lett. 63:113.
    • (1998) Immunol. Lett. , vol.63 , pp. 113
    • Martins, G.A.1    Cordoso, M.A.2    Aliberti, J.C.3    Silva, J.S.4
  • 5
    • 0028051548 scopus 로고
    • Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro
    • Vespa, G. N. R., F. Q. Cunha, and J. S. Silva. 1994. Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro. Infect. Immun. 62:5177.
    • (1994) Infect. Immun. , vol.62 , pp. 5177
    • Vespa, G.N.R.1    Cunha, F.Q.2    Silva, J.S.3
  • 6
    • 0032791044 scopus 로고    scopus 로고
    • γ Interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: A possible role in immune response control
    • Martins, G. A., L. Q. Vieira, F. Q. Cunha, and J. S. Silva. 1999. γ Interferon modulates CD95 (Fas) and CD95 ligand (Fas-L) expression and nitric oxide-induced apoptosis during the acute phase of Trypanosoma cruzi infection: a possible role in immune response control. Infect. Immun. 67:3864.
    • (1999) Infect. Immun. , vol.67 , pp. 3864
    • Martins, G.A.1    Vieira, L.Q.2    Cunha, F.Q.3    Silva, J.S.4
  • 7
    • 0028807425 scopus 로고
    • Tumor necrosis factor a mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected γ interferon-activated macrophages
    • Silva, J. S., G. N. R. Vespa, M. A. G. Cardoso, J. C. S. Aliberti, and F. Q. Cunha. 1995. Tumor necrosis factor a mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected γ interferon-activated macrophages. Infect. Immun. 63:4862.
    • (1995) Infect. Immun. , vol.63 , pp. 4862
    • Silva, J.S.1    Vespa, G.N.R.2    Cardoso, M.A.G.3    Aliberti, J.C.S.4    Cunha, F.Q.5
  • 8
    • 0025759064 scopus 로고
    • Endogenous interferon-γ, macrophage activation, and murine host defense against acute infection with Trypanosoma cruzi
    • McCabe, R. E., S. G. Meagher, and B. T. Mullins. 1991. Endogenous interferon-γ, macrophage activation, and murine host defense against acute infection with Trypanosoma cruzi. J. Infect. Dis. 163:912.
    • (1991) J. Infect. Dis. , vol.163 , pp. 912
    • McCabe, R.E.1    Meagher, S.G.2    Mullins, B.T.3
  • 11
    • 0031913243 scopus 로고    scopus 로고
    • Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in γ interferon receptor or inducible nitric oxide synthase
    • Holscher, C., G. Kohler, U. Muller, H. Mossmann, G. A. Schaub, and F. Brombacher. 1998. Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in γ interferon receptor or inducible nitric oxide synthase. Infect. Immun. 66:1208.
    • (1998) Infect. Immun. , vol.66 , pp. 1208
    • Holscher, C.1    Kohler, G.2    Muller, U.3    Mossmann, H.4    Schaub, G.A.5    Brombacher, F.6
  • 13
    • 0032931973 scopus 로고    scopus 로고
    • Costimulatory regulation of T cell function
    • Chambers, C. A., and J. P. Allison. 1999. Costimulatory regulation of T cell function. Curr. Opin. Immunol. 11:203.
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 203
    • Chambers, C.A.1    Allison, J.P.2
  • 23
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E. A. F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 5:541.
    • (1995) Immunity , vol.5 , pp. 541
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 24
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach, D. R., M. F. Krummel, and J. P. Allison. 1996. Enhancement of antitumor immunity by CTLA-4 blockade. Science 271:1734.
    • (1996) Science , vol.271 , pp. 1734
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 25
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen, J. G., M. S. Kuhns, and J. P. Allison. 2002. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3:611.
    • (2002) Nat. Immunol. , vol.3 , pp. 611
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 26
    • 0037022617 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice
    • Hurwitz, A. A., T. J. Sullivan, R. A. Sobel, and J. P. Allison. 2002. Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice. Proc. Natl. Acad. Sci. USA 99:3013.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3013
    • Hurwitz, A.A.1    Sullivan, T.J.2    Sobel, R.A.3    Allison, J.P.4
  • 27
    • 0036370969 scopus 로고    scopus 로고
    • Role of the B7-CD28/CTLA-4 pathway in autoimmune disease
    • Chang, T. T., V. K. Kuchroo, and A. H. Sharpe. 2002. Role of the B7-CD28/CTLA-4 pathway in autoimmune disease. Curr. Dir. Autoimmun 5:113.
    • (2002) Curr. Dir. Autoimmun. , vol.5 , pp. 113
    • Chang, T.T.1    Kuchroo, V.K.2    Sharpe, A.H.3
  • 29
    • 0032765697 scopus 로고    scopus 로고
    • CTLA-4 blockage enhances the immune response induced by Mycobacterium infection but does not lead to increased protection
    • Kirman, J. K., S. McCoy, M. Hook, B. Pround, I. Delahunt, A. Orme, D. Frank, and G. Le Gros. 1999. CTLA-4 blockage enhances the immune response induced by Mycobacterium infection but does not lead to increased protection. Infect. Immun. 67:3786.
    • (1999) Infect. Immun. , vol.67 , pp. 3786
    • Kirman, J.K.1    McCoy, S.2    Hook, M.3    Pround, B.4    Delahunt, I.5    Orme, A.6    Frank, D.7    Le Gros, G.8
  • 30
    • 0030872154 scopus 로고    scopus 로고
    • Protective immunity to nematode infection is induced by CTLA-4 blockade
    • McCoy, K., M. Camberis, and G. Le Gros. 1997. Protective immunity to nematode infection is induced by CTLA-4 blockade. J. Exp. Med. 186:183.
    • (1997) J. Exp. Med. , vol.186 , pp. 183
    • McCoy, K.1    Camberis, M.2    Le Gros, G.3
  • 31
    • 0032532640 scopus 로고    scopus 로고
    • Blockade of CTLA-4 enhances host resistance to the intracellular pathogen Leishmania donovani
    • Murphy, M. L., S. E. J. Cotterell, P. M. A. Gorak, C. R. Engwerda, and P. M. Kaye. 1998. Blockade of CTLA-4 enhances host resistance to the intracellular pathogen Leishmania donovani. J. Immunol. 161:4153.
    • (1998) J. Immunol. , vol.161 , pp. 4153
    • Murphy, M.L.1    Cotterell, S.E.J.2    Gorak, P.M.A.3    Engwerda, C.R.4    Kaye, P.M.5
  • 32
    • 0031739697 scopus 로고    scopus 로고
    • CTLA-4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection
    • Saha, B. S., S. Chattopadhyay, R. Germond, D. M. Harlan, and P. J. Perrin. 1998. CTLA-4 (CD152) modulates the Th subset response and alters the course of experimental Leishmania major infection. Eur. J. Immunol. 28:4213.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 4213
    • Saha, B.S.1    Chattopadhyay, S.2    Germond, R.3    Harlan, D.M.4    Perrin, P.J.5
  • 33
    • 0031766135 scopus 로고    scopus 로고
    • + T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockage of BT-1/CTLA-4 molecular pathway
    • + T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockage of BT-1/CTLA-4 molecular pathway. J. Infect. Dis. 178:1847.
    • (1998) J. Infect. Dis. , vol.178 , pp. 1847
    • Gomes, N.A.1    Barreto-De-Souza, V.2    Wilson, M.E.3    DosReis, G.A.4
  • 35
    • 0028295351 scopus 로고
    • A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry
    • Schmid, I., C. H. Uittenbogaart, B. Keld, and J. Giorgi. 1994. A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry. J. Immunol. Methods 170:145.
    • (1994) J. Immunol. Methods , vol.170 , pp. 145
    • Schmid, I.1    Uittenbogaart, C.H.2    Keld, B.3    Giorgi, J.4
  • 40
    • 0037040351 scopus 로고    scopus 로고
    • CTLA-4 upregulation during HIV infection: Association with anergy and possible target for therapeutic intervention
    • Leng, Q., Z. Bentwich, E. Magen, A. Kalinkovich, and G. Borkow. 2002. CTLA-4 upregulation during HIV infection: association with anergy and possible target for therapeutic intervention. AIDS 16:519.
    • (2002) AIDS , vol.16 , pp. 519
    • Leng, Q.1    Bentwich, Z.2    Magen, E.3    Kalinkovich, A.4    Borkow, G.5
  • 42
    • 0037369719 scopus 로고    scopus 로고
    • + T cells reside in nonlymphoid tissues during chronic Trypanosoma cruzi infection
    • + T cells reside in nonlymphoid tissues during chronic Trypanosoma cruzi infection. J. Immunol. 170:2264.
    • (2003) J. Immunol. , vol.170 , pp. 2264
    • Leavey, J.K.1    Tarleton, R.L.2
  • 43
    • 0242410967 scopus 로고    scopus 로고
    • Differential induction of TGF-β regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections
    • Omer, F. M., J. B. de Souza, and E. M. Riley. 2003. Differential induction of TGF-β regulates proinflammatory cytokine production and determines the outcome of lethal and nonlethal Plasmodium yoelii infections. J. Immunol. 171: 5430.
    • (2003) J. Immunol. , vol.171 , pp. 5430
    • Omer, F.M.1    De Souza, J.B.2    Riley, E.M.3
  • 44
    • 0037128654 scopus 로고    scopus 로고
    • Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells
    • Gilliet, M., and Y. J. Liu. 2002. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195:695.
    • (2002) J. Exp. Med. , vol.195 , pp. 695
    • Gilliet, M.1    Liu, Y.J.2
  • 46
    • 0036717722 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T cells provoke a shift in the Th1/2 paradigm in immunity to infectious diseases
    • McGuirck, P., and K. Mills. 2002. Pathogen-specific regulatory T cells provoke a shift in the Th1/2 paradigm in immunity to infectious diseases. Trends Immunol. 23:450.
    • (2002) Trends Immunol. , vol.23 , pp. 450
    • McGuirck, P.1    Mills, K.2
  • 47
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone, J. A., and A. K. Abbas. 2003. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3:253.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 253
    • Bluestone, J.A.1    Abbas, A.K.2
  • 49
    • 0030043392 scopus 로고    scopus 로고
    • Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression
    • Gong, J. H., M. Zhang, R. L. Modlin, P. S. Linsley, D. Iyer, Y. Lin, and P. F. Barnes. 1996. Interleukin-10 downregulates Mycobacterium tuberculosis-induced Th1 responses and CTLA-4 expression. Infect. Immun. 64:913.
    • (1996) Infect. Immun. , vol.64 , pp. 913
    • Gong, J.H.1    Zhang, M.2    Modlin, R.L.3    Linsley, P.S.4    Iyer, D.5    Lin, Y.6    Barnes, P.F.7
  • 51
    • 0030025945 scopus 로고    scopus 로고
    • Regulation of Trypanosoma cruzi infection in mice by γ interferon and interleukin 10: Role of NK cells
    • Cardillo, F., J. C. Voltarelli, S. G. Reed, and J. S. Silva. 1996. Regulation of Trypanosoma cruzi infection in mice by γ interferon and interleukin 10: role of NK cells. Infect. Immun. 64:128.
    • (1996) Infect. Immun. , vol.64 , pp. 128
    • Cardillo, F.1    Voltarelli, J.C.2    Reed, S.G.3    Silva, J.S.4
  • 54
    • 0025741792 scopus 로고
    • Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor β (TGF-β)
    • Silva, J. S., D. R. Twardzik, and S. G. Reed. 1991. Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor β (TGF-β). J. Exp. Med. 174:539.
    • (1991) J. Exp. Med. , vol.174 , pp. 539
    • Silva, J.S.1    Twardzik, D.R.2    Reed, S.G.3
  • 57
    • 78651184807 scopus 로고
    • Chronic and progressive myocarditis and myositis in C3H mice infected with Trypanosoma cruzi
    • Federici, E. E., W. B. Abelmann, and F. A. Neva. 1964. Chronic and progressive myocarditis and myositis in C3H mice infected with Trypanosoma cruzi. Am. J. Trop. Med. Hyg. 13:272.
    • (1964) Am. J. Trop. Med. Hyg. , vol.13 , pp. 272
    • Federici, E.E.1    Abelmann, W.B.2    Neva, F.A.3


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