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Volumn 1, Issue 6, 2001, Pages 455-466

Hypertriglyceridemia: Associated risks and effect of drug treatment

Author keywords

[No Author keywords available]

Indexed keywords

CLOFIBRIC ACID; DRUG DERIVATIVE; FISH OIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; TRIACYLGLYCEROL;

EID: 1842511750     PISSN: 11753277     EISSN: 1179187X     Source Type: Journal    
DOI: 10.2165/00129784-200101060-00005     Document Type: Article
Times cited : (18)

References (138)
  • 2
    • 0027065022 scopus 로고
    • Epidemiology of triglycerides: A view from Framingham
    • Castelli WP. Epidemiology of triglycerides: a view from Framingham. Am J Cardiol 1992; 70: 3H-9
    • (1992) Am J Cardiol , vol.70
    • Castelli, W.P.1
  • 3
    • 0031679196 scopus 로고    scopus 로고
    • The emergence of triglycerides as a significant independent risk factor in coronary artery disease
    • Assmann G, Schulte H, Funke H, et al. The emergence of triglycerides as a significant independent risk factor in coronary artery disease. Eur Heart J 1998; 19: M8-14
    • (1998) Eur Heart J , vol.19
    • Assmann, G.1    Schulte, H.2    Funke, H.3
  • 4
    • 20244370323 scopus 로고
    • Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial)
    • Goldbourt U, Behar S, Reicher-Reiss H, et al. Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial). Am J Cardiol 1993; 71: 909-15
    • (1993) Am J Cardiol , vol.71 , pp. 909-915
    • Goldbourt, U.1    Behar, S.2    Reicher-Reiss, H.3
  • 5
    • 58149212612 scopus 로고
    • Distribution of lipids in 8,500 men with coronary artery disease
    • Department of Veterans Affairs HDL Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, et al. Distribution of lipids in 8,500 men with coronary artery disease. Department of Veterans Affairs HDL Intervention Trial Study Group. Am J Cardiol 1995; 75: 1196-201
    • (1995) Am J Cardiol , vol.75 , pp. 1196-1201
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 6
    • 0015348189 scopus 로고
    • Estimation of the concentration of lowdensity lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of lowdensity lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 7
    • 0031458498 scopus 로고    scopus 로고
    • Lipoprotein heterogeneity and apolipoprotein b metabolism
    • Packard CJ, Shepherd J. Lipoprotein heterogeneity and apolipoprotein B metabolism. Arterioscler Thromb Vasc Biol 1997; 17: 3542-56
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3542-3556
    • Packard, C.J.1    Shepherd, J.2
  • 8
    • 0029658941 scopus 로고    scopus 로고
    • Heterozygosity for Asn291->Ser mutation in the lipoprotein lipase gene in two Finnish pedigrees: Effect of hyperinsulinemia on the expression of hypertriglyceridemia
    • Syvanne M, Antikainen M, Ehnholm S, et al. Heterozygosity for Asn291->Ser mutation in the lipoprotein lipase gene in two Finnish pedigrees: effect of hyperinsulinemia on the expression of hypertriglyceridemia. J Lipid Res 1996; 37: 727-38
    • (1996) J Lipid Res , vol.37 , pp. 727-738
    • Syvanne, M.1    Antikainen, M.2    Ehnholm, S.3
  • 9
    • 0028889944 scopus 로고
    • Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of french canadian descent
    • Minnich A, Kessling A, Roy M, et al. Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of French Canadian descent. J Lipid Res 1995; 36: 117-24
    • (1995) J Lipid Res , vol.36 , pp. 117-124
    • Minnich, A.1    Kessling, A.2    Roy, M.3
  • 10
    • 0023265425 scopus 로고
    • DNA polymorphisms of apolipoprotein A-I/C-III and insulin genes in familial hypertriglyceridemia and coronary heart disease
    • Aalto-Setala K, Kontula K, Sane T, et al. DNA polymorphisms of apolipoprotein A-I/C-III and insulin genes in familial hypertriglyceridemia and coronary heart disease. Atherosclerosis 1987; 66: 145-52
    • (1987) Atherosclerosis , vol.66 , pp. 145-152
    • Aalto-Setala, K.1    Kontula, K.2    Sane, T.3
  • 11
    • 0031768693 scopus 로고    scopus 로고
    • Increased risk for endogenous hypertriglyceridaemia is associated with an apolipoprotein C3 haplotype specified by the SstI polymorphism
    • Hoffer MJ, Sijbrands EJ, De Man FH, et al. Increased risk for endogenous hypertriglyceridaemia is associated with an apolipoprotein C3 haplotype specified by the SstI polymorphism. Eur J Clin Invest 1998; 28: 807-12
    • (1998) Eur J Clin Invest , vol.28 , pp. 807-812
    • Hoffer, M.J.1    Sijbrands, E.J.2    De Man, F.H.3
  • 12
    • 0014916078 scopus 로고
    • Classification of hyperlipidaemias and hyperlipoproteinaemias
    • Beaumont JL, Carlson LA, Cooper GR, et al. Classification of hyperlipidaemias and hyperlipoproteinaemias. Bull World Health Organ 1970; 43: 891-915
    • (1970) Bull World Health Organ , vol.43 , pp. 891-915
    • Beaumont, J.L.1    Carlson, L.A.2    Cooper, G.R.3
  • 14
    • 0027410566 scopus 로고
    • Plasma triglyceride level and mortality from coronary heart disease
    • Criqui MH, Heiss G, Cohn R, et al. Plasma triglyceride level and mortality from coronary heart disease. N Engl J Med 1993; 328: 1220-5
    • (1993) N Engl J Med , vol.328 , pp. 1220-1225
    • Criqui, M.H.1    Heiss, G.2    Cohn, R.3
  • 15
    • 0001575895 scopus 로고
    • Type III hyperlipoproteinemia (dysbetalipoproteinemia): The role of apolipoprotein e in normal and asbnormal lipoprotein metabolism
    • Scriver C, Beaudet A, Sly W, et al. editors. New York: McGraw-Hill
    • Mahley RW, Rall S. Type III hyperlipoproteinemia (dysbetalipoproteinemia) : the role of apolipoprotein E in normal and asbnormal lipoprotein metabolism. In: Scriver C, Beaudet A, Sly W, et al. editors. The metabolic and molecular bases of inherited disease. New York: McGraw-Hill, 1995: 1953-80
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , pp. 1953-1980
    • Mahley, R.W.1    Rall, S.2
  • 16
    • 0016592462 scopus 로고
    • Gallbladder disease in hyperlipoproteinaemia
    • Einarsson K, Hellstrom K, Kallner M. Gallbladder disease in hyperlipoproteinaemia. Lancet 1975; 1: 484-7
    • (1975) Lancet , vol.1 , pp. 484-487
    • Einarsson, K.1    Hellstrom, K.2    Kallner, M.3
  • 17
    • 0018359558 scopus 로고
    • Prevalence of gallbladder disease in hyperlipoproteinemia
    • Ahlberg J, Angelin B, Einarsson K, et al. Prevalence of gallbladder disease in hyperlipoproteinemia. Dig Dis Sci 1979; 24: 459-64
    • (1979) Dig Dis Sci , vol.24 , pp. 459-464
    • Ahlberg, J.1    Angelin, B.2    Einarsson, K.3
  • 18
    • 0031855022 scopus 로고    scopus 로고
    • Is hypertriglyceridaemia an independent risk factor for coronary heart disease? the epidemiological evidence
    • Miller M. Is hypertriglyceridaemia an independent risk factor for coronary heart disease? The epidemiological evidence. Eur Heart J 1998; 19: H18-22
    • (1998) Eur Heart J , vol.19
    • Miller, M.1
  • 19
    • 0021182418 scopus 로고
    • Abnormalities in very low, low and high density lipoproteins in hypertriglyceridemia. Reversal toward normal with bezafibrate treatment
    • Eisenberg S, Gavish D, Oschry Y, et al. Abnormalities in very low, low and high density lipoproteins in hypertriglyceridemia. Reversal toward normal with bezafibrate treatment. J Clin Invest 1984; 74: 470-82
    • (1984) J Clin Invest , vol.74 , pp. 470-482
    • Eisenberg, S.1    Gavish, D.2    Oschry, Y.3
  • 20
    • 0034503308 scopus 로고    scopus 로고
    • The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia is mediated by upregulation of lipoprotein lipase: No effects on VLDL substrate affinity to lipolysis or LDL receptor binding
    • De Man FH, de Beer F, van der Laarse A, et al. The hypolipidemic action of bezafibrate therapy in hypertriglyceridemia is mediated by upregulation of lipoprotein lipase: no effects on VLDL substrate affinity to lipolysis or LDL receptor binding. Atherosclerosis 2000: 153: 363-71
    • (2000) Atherosclerosis , vol.153 , pp. 363-371
    • De Man, F.H.1    De Beer, F.2    Van Der Laarse, A.3
  • 21
    • 0021954138 scopus 로고
    • Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III
    • Wang CS, McConathy WJ, Kloer HU, et al. Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. J Clin Invest 1985; 75: 384-90
    • (1985) J Clin Invest , vol.75 , pp. 384-390
    • Wang, C.S.1    McConathy, W.J.2    Kloer, H.U.3
  • 22
    • 0028069690 scopus 로고
    • Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein e
    • de Silva HV, Lauer SJ, Wang J, et al. Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E. J Biol Chem 1994; 269: 2324-35
    • (1994) J Biol Chem , vol.269 , pp. 2324-2335
    • De Silva, H.V.1    Lauer, S.J.2    Wang, J.3
  • 23
    • 0028172762 scopus 로고
    • Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque
    • Rapp JH, Lespine A, Hamilton RL, et al. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb 1994; 14: 1767-74
    • (1994) Arterioscler Thromb , vol.14 , pp. 1767-1774
    • Rapp, J.H.1    Lespine, A.2    Hamilton, R.L.3
  • 24
    • 0019966307 scopus 로고
    • Hypertriglyceridemic very low density lipoproteins induce triglyceride synthesis and accumulation in mouse peritoneal macrophages
    • Gianturco SH, Bradley WA, Gotto AM, et al. Hypertriglyceridemic very low density lipoproteins induce triglyceride synthesis and accumulation in mouse peritoneal macrophages. J Clin Invest 1982; 70: 168-78
    • (1982) J Clin Invest , vol.70 , pp. 168-178
    • Gianturco, S.H.1    Bradley, W.A.2    Gotto, A.M.3
  • 25
    • 0026284533 scopus 로고
    • Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia
    • Mann CJ, Yen FT, Grant AM, et al. Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia. J Clin Invest 1991; 88: 2059-66
    • (1991) J Clin Invest , vol.88 , pp. 2059-2066
    • Mann, C.J.1    Yen, F.T.2    Grant, A.M.3
  • 26
    • 0028883659 scopus 로고
    • Triglycerides are major determinants of cholesterol esterification/ transfer and HDL remodeling in human plasma
    • Murakami T, Michelagnoli S, Longhi R, et al. Triglycerides are major determinants of cholesterol esterification/transfer and HDL remodeling in human plasma. Arterioscler Thromb Vasc Biol 1995; 15: 1819-28
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1819-1828
    • Murakami, T.1    Michelagnoli, S.2    Longhi, R.3
  • 27
    • 0017229447 scopus 로고
    • The metabolism of low density lipoprotein in endogenous hypertriglyceridaemia
    • Sigurdsson G, Nicoll A, Lewis B. The metabolism of low density lipoprotein in endogenous hypertriglyceridaemia. Eur J Clin Invest 1979; 6: 151-8
    • (1979) Eur J Clin Invest , vol.6 , pp. 151-158
    • Sigurdsson, G.1    Nicoll, A.2    Lewis, B.3
  • 28
    • 0021919071 scopus 로고
    • Fenofibrate reduces low density lipoprotein catabolism in hypertriglyceridemic subjects
    • Shepherd J, Caslake MJ, Lorimer AR, et al. Fenofibrate reduces low density lipoprotein catabolism in hypertriglyceridemic subjects. Arteriosclerosis 1985; 5: 162-8
    • (1985) Arteriosclerosis , vol.5 , pp. 162-168
    • Shepherd, J.1    Caslake, M.J.2    Lorimer, A.R.3
  • 29
    • 0027220709 scopus 로고
    • Activities of lipoprotein lipase and hepatic triglyceride lipase in postheparin plasma of patients with low concentrations of HDL cholesterol
    • Blades B, Vega GL, Grundy SM. Activities of lipoprotein lipase and hepatic triglyceride lipase in postheparin plasma of patients with low concentrations of HDL cholesterol. Arterioscler Thromb 1993; 13: 1227-35
    • (1993) Arterioscler Thromb , vol.13 , pp. 1227-1235
    • Blades, B.1    Vega, G.L.2    Grundy, S.M.3
  • 30
    • 0031028793 scopus 로고    scopus 로고
    • Determinants of plasma HDL-cholesterol in hypertriglyceridemic patients. Role of cholesterol-ester transfer protein and lecithin cholesteryl acyl transferase
    • Tato F, Vega GL, Grundy SM. Determinants of plasma HDL-cholesterol in hypertriglyceridemic patients. Role of cholesterol-ester transfer protein and lecithin cholesteryl acyl transferase. Arterioscler Thromb Vasc Biol 1997; 17: 56-63
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 56-63
    • Tato, F.1    Vega, G.L.2    Grundy, S.M.3
  • 31
    • 0033669366 scopus 로고    scopus 로고
    • Therapeutic modulation of low-density lipoprotein size
    • Marais AD. Therapeutic modulation of low-density lipoprotein size. Curr Opin Lipidol 2000; 11: 597-602
    • (2000) Curr Opin Lipidol , vol.11 , pp. 597-602
    • Marais, A.D.1
  • 32
    • 0023807047 scopus 로고
    • Low-density lipoprotein subclass patterns and risk of myocardial infarction
    • Austin MA, Breslow JL, Hennekens CH, et al. Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA 1988; 260: 1917-21
    • (1988) JAMA , vol.260 , pp. 1917-1921
    • Austin, M.A.1    Breslow, J.L.2    Hennekens, C.H.3
  • 33
    • 0030565005 scopus 로고    scopus 로고
    • Influence of plasma lipid and LDL-subfraction profile on the interaction between low density lipoprotein with human arterial wall proteoglycans
    • Anber V, Griffin BA, McConnell M, et al. Influence of plasma lipid and LDL-subfraction profile on the interaction between low density lipoprotein with human arterial wall proteoglycans. Atherosclerosis 1996; 124: 261-71
    • (1996) Atherosclerosis , vol.124 , pp. 261-271
    • Anber, V.1    Griffin, B.A.2    McConnell, M.3
  • 34
    • 0039228154 scopus 로고    scopus 로고
    • Accumulation of lipoprotein fractions and subfractions in the arterial wall, determined in an in vitro perfusion system
    • Bjornheden T, Babyi A, Bondjers G, et al. Accumulation of lipoprotein fractions and subfractions in the arterial wall, determined in an in vitro perfusion system. Atherosclerosis 1996; 123: 43-56
    • (1996) Atherosclerosis , vol.123 , pp. 43-56
    • Bjornheden, T.1    Babyi, A.2    Bondjers, G.3
  • 35
    • 0033758603 scopus 로고    scopus 로고
    • Normal oxidative stress and enhanced lipoprotein resistance to in vitro oxidation in hypertriglyceridemia: Effects of bezafibrate therapy
    • De Man FH, Jonkers IJ, Schwedhelm E, et al. Normal oxidative stress and enhanced lipoprotein resistance to in vitro oxidation in hypertriglyceridemia: effects of bezafibrate therapy. Arterioscler Thromb Vasc Biol 2000; 20: 2434-40
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2434-2440
    • De Man, F.H.1    Jonkers, I.J.2    Schwedhelm, E.3
  • 36
    • 0032567996 scopus 로고    scopus 로고
    • Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome
    • Grundy SM. Hypertriglyceridemia, atherogenic dyslipidemia, and the metabolic syndrome. Am J Cardiol 1998; 81: 18B-25
    • (1998) Am J Cardiol , vol.81
    • Grundy, S.M.1
  • 37
    • 0031832118 scopus 로고    scopus 로고
    • Abnormal metabolism of free fatty acids in hypertriglyceridaemic men: Apparent insulin resistance of adipose tissue
    • Mostaza JM, Vega GL, Snell P, et al. Abnormal metabolism of free fatty acids in hypertriglyceridaemic men: apparent insulin resistance of adipose tissue. J Intern Med 1998; 243: 265-74
    • (1998) J Intern Med , vol.243 , pp. 265-274
    • Mostaza, J.M.1    Vega, G.L.2    Snell, P.3
  • 38
    • 0028695552 scopus 로고
    • Hyperinsulinaemia and hypertriglyceridaemia
    • Steiner G. Hyperinsulinaemia and hypertriglyceridaemia. J Intern Med 1994; 736 Suppl.: 23-6
    • (1994) J Intern Med , vol.736 , Issue.SUPPL. , pp. 23-26
    • Steiner, G.1
  • 39
    • 0028883205 scopus 로고
    • Changes of lipolytic enzymes cluster with insulin resistance syndrome
    • Botnia Study Group
    • Knudsen P, Eriksson J, Lahdenpera S, et al. Changes of lipolytic enzymes cluster with insulin resistance syndrome. Botnia Study Group. Diabetologia 1995; 38: 344-50
    • (1995) Diabetologia , vol.38 , pp. 344-350
    • Knudsen, P.1    Eriksson, J.2    Lahdenpera, S.3
  • 40
    • 0025936533 scopus 로고
    • Altering triglyceride concentrations changes insulin-glucose relationships in hypertriglyceridemic patients. Double-blind study with gemfibrozil with implications for atherosclerosis
    • Steiner G. Altering triglyceride concentrations changes insulin-glucose relationships in hypertriglyceridemic patients. Double-blind study with gemfibrozil with implications for atherosclerosis. Diabetes Care 1991; 14: 1077-81
    • (1991) Diabetes Care , vol.14 , pp. 1077-1081
    • Steiner, G.1
  • 41
    • 0029862973 scopus 로고    scopus 로고
    • Hyperinsulinemia as an independent risk factor for ischemic heart disease
    • Despres JP, Lamarche B, Mauriege P, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996; 334: 952-7
    • (1996) N Engl J Med , vol.334 , pp. 952-957
    • Despres, J.P.1    Lamarche, B.2    Mauriege, P.3
  • 42
    • 0030025673 scopus 로고    scopus 로고
    • Hypertension and associated metabolic abnormalities - The role of insulin resistance and the sympathoadrenal system
    • Reaven GM, Lithell H, Landsberg L. Hypertension and associated metabolic abnormalities - the role of insulin resistance and the sympathoadrenal system. N Engl J Med 1996; 334: 374-81
    • (1996) N Engl J Med , vol.334 , pp. 374-381
    • Reaven, G.M.1    Lithell, H.2    Landsberg, L.3
  • 43
    • 0032510639 scopus 로고    scopus 로고
    • Prediction of coronary heart disease using risk factor categories
    • Wilson PW, D?Agostino RB, Levy D, et al. Prediction of coronary heart disease using risk factor categories. Circulation 1998; 97: 1837-47
    • (1998) Circulation , vol.97 , pp. 1837-1847
    • Wilson, P.W.1    Dagostino, R.B.2    Levy, D.3
  • 44
    • 0030921893 scopus 로고    scopus 로고
    • Elevated circulating free fatty acid levels impair endothelium-Dependent vasodilation
    • Steinberg HO, Tarshoby M, Monestel R, et al. Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest 1997; 100: 1230-9
    • (1997) J Clin Invest , vol.100 , pp. 1230-1239
    • Steinberg, H.O.1    Tarshoby, M.2    Monestel, R.3
  • 45
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • Steinberg HO, Chaker H, Leaming R, et al. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97: 2601-10
    • (1996) J Clin Invest , vol.97 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3
  • 46
    • 0035152499 scopus 로고    scopus 로고
    • Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: Protective effect of vitamin c
    • Perticone F, Ceravolo R, Candigliota M, et al. Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C. Diabetes 2001; 50: 159-65
    • (2001) Diabetes , vol.50 , pp. 159-165
    • Perticone, F.1    Ceravolo, R.2    Candigliota, M.3
  • 47
    • 0018932163 scopus 로고
    • Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction
    • DeWood MA, Spores J, Notske R, et al. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. N Engl J Med 1980; 303: 897-902
    • (1980) N Engl J Med , vol.303 , pp. 897-902
    • Dewood, M.A.1    Spores, J.2    Notske, R.3
  • 48
    • 0022485106 scopus 로고
    • Haemostatic function and ischaemic heart disease: Principal results of the northwick park heart study
    • Meade TW, Mellows S, Brozovic M, et al. Haemostatic function and ischaemic heart disease: principal results of the Northwick Park Heart Study. Lancet 1986; II: 533-7
    • (1986) Lancet , vol.2 , pp. 533-537
    • Meade, T.W.1    Mellows, S.2    Brozovic, M.3
  • 49
    • 0033022434 scopus 로고    scopus 로고
    • Measuring plasma fibrinogen to predict stroke and myocardial infarction: An update
    • Maresca G, Di Blasio A, Marchioli R, et al. Measuring plasma fibrinogen to predict stroke and myocardial infarction: an update. Arterioscler Thromb Vasc Biol 1999; 19: 1368-77
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1368-1377
    • Maresca, G.1    Di Blasio, A.2    Marchioli, R.3
  • 50
    • 0028909230 scopus 로고
    • Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris
    • European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group
    • Thompson SG, Kienast J, Pyke SD, et al. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. N Engl J Med 1995; 332: 635-41
    • (1995) N Engl J Med , vol.332 , pp. 635-641
    • Thompson, S.G.1    Kienast, J.2    Pyke, S.D.3
  • 51
    • 0034610405 scopus 로고    scopus 로고
    • Comparison of novel hemostatic factors and conventional risk factors for prediction of coronary heart disease
    • Cooper JA, Miller GJ, Bauer KA, et al. Comparison of novel hemostatic factors and conventional risk factors for prediction of coronary heart disease. Circulation 2000; 102: 2816-22
    • (2000) Circulation , vol.102 , pp. 2816-2822
    • Cooper, J.A.1    Miller, G.J.2    Bauer, K.A.3
  • 52
    • 0030961173 scopus 로고    scopus 로고
    • Coagulation factor VII and the risk of coronary heart disease in healthy men
    • Junker R, Heinrich J, Schulte H, et al. Coagulation factor VII and the risk of coronary heart disease in healthy men. Arterioscler Thromb Vasc Biol 1997; 17: 1539-44
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1539-1544
    • Junker, R.1    Heinrich, J.2    Schulte, H.3
  • 53
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction
    • Hamsten A, Wiman B, de Faire U, et al. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 1985; 313: 1557-63
    • (1985) N Engl J Med , vol.313 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.2    De Faire, U.3
  • 54
    • 0020536979 scopus 로고
    • Hypertriglyceridaemia and hypercoagulability
    • Simpson HC, Mann JI, Meade TW, et al. Hypertriglyceridaemia and hypercoagulability. Lancet 1983; 1: 786-90
    • (1983) Lancet , vol.1 , pp. 786-790
    • Simpson, H.C.1    Mann, J.I.2    Meade, T.W.3
  • 55
    • 0027195040 scopus 로고
    • Fibrinolysis in hypertriglyceridaemic subjects in response to venous occlusion
    • Avellone G, Di Garbo V, Cordova R, et al. Fibrinolysis in hypertriglyceridaemic subjects in response to venous occlusion. Blood Coagul Fibrinolysis 1993; 4: 429-33
    • (1993) Blood Coagul Fibrinolysis , vol.4 , pp. 429-433
    • Avellone, G.1    Di Garbo, V.2    Cordova, R.3
  • 56
    • 0032858276 scopus 로고    scopus 로고
    • Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia
    • Minnema MC, Wittekoek ME, Schoonenboom N, et al. Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia. Arterioscler Thromb Vasc Biol 1999; 19: 2548-53
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2548-2553
    • Minnema, M.C.1    Wittekoek, M.E.2    Schoonenboom, N.3
  • 57
    • 0033812287 scopus 로고    scopus 로고
    • Activated platelets in patients with severe hypertriglyceridemia: Effects of triglyceride-lowering therapy
    • De Man FH, Nieuwland R, van der Laarse A, et al. Activated platelets in patients with severe hypertriglyceridemia: effects of triglyceride-lowering therapy. Atherosclerosis 2000; 152: 407-14
    • (2000) Atherosclerosis , vol.152 , pp. 407-414
    • De Man, F.H.1    Nieuwland, R.2    Van Der Laarse, A.3
  • 58
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999; 340: 115-26
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 59
    • 0025177196 scopus 로고
    • Elevation of C-reactive protein in ?Active? Coronary artery disease
    • Berk BC, Weintraub WS, Alexander RW. Elevation of C-reactive protein in ?active? coronary artery disease. Am J Cardiol 1990; 65: 168-72
    • (1990) Am J Cardiol , vol.65 , pp. 168-172
    • Berk, B.C.1    Weintraub, W.S.2    Alexander, R.W.3
  • 60
    • 0029830113 scopus 로고    scopus 로고
    • Elevated levels of interleukin-6 in unstable angina
    • Biasucci LM, Vitelli A, Liuzzo G, et al. Elevated levels of interleukin-6 in unstable angina. Circulation 1996; 94: 874-7
    • (1996) Circulation , vol.94 , pp. 874-877
    • Biasucci, L.M.1    Vitelli, A.2    Liuzzo, G.3
  • 61
    • 0033980494 scopus 로고    scopus 로고
    • Hyperlipoproteinemia affects cytokine production in whole blood samples ex vivo. The influence of lipid-lowering therapy
    • Mohrschladt MF, Weverling-Rijnsburger AW, De Man FH, et al. Hyperlipoproteinemia affects cytokine production in whole blood samples ex vivo. The influence of lipid-lowering therapy. Atherosclerosis 2000; 148: 413-9
    • (2000) Atherosclerosis , vol.148 , pp. 413-419
    • Mohrschladt, M.F.1    Weverling-Rijnsburger, A.W.2    De Man, F.H.3
  • 62
    • 0031861698 scopus 로고    scopus 로고
    • Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion
    • Abe Y, El-Masri B, Kimball KT, et al. Soluble cell adhesion molecules in hypertriglyceridemia and potential significance on monocyte adhesion. Arterioscler Thromb Vasc Biol 1998; 18: 723-31
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 723-731
    • Abe, Y.1    El-Masri, B.2    Kimball, K.T.3
  • 63
    • 0034601747 scopus 로고    scopus 로고
    • Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the framingham offspring population
    • Stec JJ, Silbershatz H, Tofler GH, et al. Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the Framingham Offspring Population. Circulation 2000; 102: 1634-8
    • (2000) Circulation , vol.102 , pp. 1634-1638
    • Stec, J.J.1    Silbershatz, H.2    Tofler, G.H.3
  • 64
    • 0029001374 scopus 로고
    • Plasma fibrinogen levels and their correlates in 6457 coronary heart disease patients
    • The Bezafibrate Infarction Prevention (BIP) Study
    • Barasch E, Benderly M, Graff E, et al. Plasma fibrinogen levels and their correlates in 6457 coronary heart disease patients. The Bezafibrate Infarction Prevention (BIP) Study. J Clin Epidemiol 1995; 48: 757-65
    • (1995) J Clin Epidemiol , vol.48 , pp. 757-765
    • Barasch, E.1    Benderly, M.2    Graff, E.3
  • 65
    • 0034669480 scopus 로고    scopus 로고
    • Clustering of procoagulation, inflammation, and fibrinolysis variables with metabolic factors in insulin resistance syndrome
    • Sakkinen PA, Wahl P, Cushman M, et al. Clustering of procoagulation, inflammation, and fibrinolysis variables with metabolic factors in insulin resistance syndrome. Am J Epidemiol 2000; 152: 897-907
    • (2000) Am J Epidemiol , vol.152 , pp. 897-907
    • Sakkinen, P.A.1    Wahl, P.2    Cushman, M.3
  • 66
    • 0034577768 scopus 로고    scopus 로고
    • Raised interleukin-6 levels in obese patients
    • Roytblat L, Rachinsky M, Fisher A, et al. Raised interleukin-6 levels in obese patients. Obes Res 2000; 8: 673-5
    • (2000) Obes Res , vol.8 , pp. 673-675
    • Roytblat, L.1    Rachinsky, M.2    Fisher, A.3
  • 67
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-Alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, et al. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995; 95: 2409-15
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3
  • 68
    • 0002746856 scopus 로고
    • Serum triglycerides in coronary artery disease
    • Albrink M, Man E. Serum triglycerides in coronary artery disease. Ann Intern Med 1959; 103: 4-8
    • (1959) Ann Intern Med , vol.103 , pp. 4-8
    • Albrink, M.1    Man, E.2
  • 69
    • 0029884921 scopus 로고    scopus 로고
    • Hypertriglyceridemia and elevated lipoprotein(a) are risk factors for major coronary events in middle-aged men
    • Assmann G, Schulte H, von Eckardstein A. Hypertriglyceridemia and elevated lipoprotein(a) are risk factors for major coronary events in middle-aged men. Am J Cardiol 1996; 77: 1179-84
    • (1996) Am J Cardiol , vol.77 , pp. 1179-1184
    • Assmann, G.1    Schulte, H.2    Von Eckardstein, A.3
  • 70
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A metaanalysis of population-based prospective studies
    • Hokanson JE, Austin MA. Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a metaanalysis of population-based prospective studies. J Cardiovasc Risk 1996; 3: 213-9
    • (1996) J Cardiovasc Risk , vol.3 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 71
    • 0021320980 scopus 로고
    • Interpreting multiple logistic regression coefficients in prospective observational studies
    • Abbott RD, Carroll RJ. Interpreting multiple logistic regression coefficients in prospective observational studies. Am J Epidemiol 1984; 119: 830-6
    • (1984) Am J Epidemiol , vol.119 , pp. 830-836
    • Abbott, R.D.1    Carroll, R.J.2
  • 72
    • 0032562257 scopus 로고    scopus 로고
    • Triglyceride concentration and ischemic heart disease: An eight-year follow-up in the copenhagen male study
    • Jeppesen J, Hein HO, Suadicani P, et al. Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study. Circulation 1998; 97: 1029-36
    • (1998) Circulation , vol.97 , pp. 1029-1036
    • Jeppesen, J.1    Hein, H.O.2    Suadicani, P.3
  • 73
    • 0030977706 scopus 로고    scopus 로고
    • Preserved endothelial function in patients with severe hypertriglyceridemia and low functional lipoprotein lipase activity
    • Chowienczyk PJ, Watts GF, Wierzbicki AS, et al. Preserved endothelial function in patients with severe hypertriglyceridemia and low functional lipoprotein lipase activity. J Am Coll Cardiol 1997; 29: 964-8
    • (1997) J Am Coll Cardiol , vol.29 , pp. 964-968
    • Chowienczyk, P.J.1    Watts, G.F.2    Wierzbicki, A.S.3
  • 74
    • 0032720865 scopus 로고    scopus 로고
    • Impaired brachial artery endothelial function is not predicted by elevated triglycerides
    • Schnell GB, Robertson A, Houston D, et al. Impaired brachial artery endothelial function is not predicted by elevated triglycerides. J Am Coll Cardiol 1999; 33: 2038-43
    • (1999) J Am Coll Cardiol , vol.33 , pp. 2038-2043
    • Schnell, G.B.1    Robertson, A.2    Houston, D.3
  • 75
    • 0033101497 scopus 로고    scopus 로고
    • Endothelium-dependent relaxation by acetylcholine is impaired in hypertriglyceridemic humans with normal levels of plasma LDL cholesterol
    • Lewis TV, Dart AM, Chin-Dusting JP. Endothelium-dependent relaxation by acetylcholine is impaired in hypertriglyceridemic humans with normal levels of plasma LDL cholesterol. J Am Coll Cardiol 1999; 33: 805-12
    • (1999) J Am Coll Cardiol , vol.33 , pp. 805-812
    • Lewis, T.V.1    Dart, A.M.2    Chin-Dusting, J.P.3
  • 76
    • 0034098951 scopus 로고    scopus 로고
    • Not acute but chronic hypertriglyceridemia is associated with impaired endotheliumdependent vasodilation: Reversal after lipid-lowering therapy by atorvastatin
    • De Man FH, Weverling-Rijnsburger AW, van der Laarse A, et al. Not acute but chronic hypertriglyceridemia is associated with impaired endotheliumdependent vasodilation: reversal after lipid-lowering therapy by atorvastatin. Arterioscler Thromb Vasc Biol 2000; 20: 744-50
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 744-750
    • De Man, F.H.1    Weverling-Rijnsburger, A.W.2    Van Der Laarse, A.3
  • 77
    • 0033828740 scopus 로고    scopus 로고
    • Flow-mediated vasoactivity and circulating adhesion molecules in hypertriglyceridemia: Association with small, dense LDL cholesterol particles
    • Lupattelli G, Lombardini R, Schillaci G, et al. Flow-mediated vasoactivity and circulating adhesion molecules in hypertriglyceridemia: association with small, dense LDL cholesterol particles. Am Heart J 2000; 140: 521-6
    • (2000) Am Heart J , vol.140 , pp. 521-526
    • Lupattelli, G.1    Lombardini, R.2    Schillaci, G.3
  • 78
    • 0028154543 scopus 로고
    • Second report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel II)
    • National Cholesterol Education Program
    • National Cholesterol Education Program. Second report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel II). Circulation 1994; 89: 1333-445
    • (1994) Circulation , vol.89 , pp. 1333-1445
  • 79
    • 0032054839 scopus 로고    scopus 로고
    • Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease
    • Fibrate Consensus Group
    • Fruchart JC, Brewer HBJ, Leitersdorf E. Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease. Fibrate Consensus Group. Am J Cardiol 1998; 81: 912-7
    • (1998) Am J Cardiol , vol.81 , pp. 912-917
    • Fruchart, J.C.1    Brewer, H.B.J.2    Leitersdorf, E.3
  • 80
    • 0033015597 scopus 로고    scopus 로고
    • Dietary counselling effectively improves lipid levels in patients with endogenous hypertriglyceridemia: Emphasis on weight reduction and alcohol limitation
    • De Man FH, van der Laarse A, Hopman EG, et al. Dietary counselling effectively improves lipid levels in patients with endogenous hypertriglyceridemia: emphasis on weight reduction and alcohol limitation. Eur J Clin Nutr 1999; 53: 413-8
    • (1999) Eur J Clin Nutr , vol.53 , pp. 413-418
    • De Man, F.H.1    Van Der Laarse, A.2    Hopman, E.G.3
  • 81
    • 0028198796 scopus 로고
    • Short-Term response to dietary counseling of hyperlipidemic outpatients of a lipid clinic
    • Dallongeville J, Leboeuf N, Blais C, et al. Short-term response to dietary counseling of hyperlipidemic outpatients of a lipid clinic. J Am Diet Assoc 1994; 94: 616-21
    • (1994) J Am Diet Assoc , vol.94 , pp. 616-621
    • Dallongeville, J.1    Leboeuf, N.2    Blais, C.3
  • 82
    • 0025923533 scopus 로고
    • Management of hypertriglyceridemic patients. B. Dietary management of hypertriglyceridemic patients
    • Carmena R, Grundy SM. Management of hypertriglyceridemic patients. B. Dietary management of hypertriglyceridemic patients. Am J Cardiol 1991; 68: 35A-7
    • (1991) Am J Cardiol , vol.68
    • Carmena, R.1    Grundy, S.M.2
  • 83
    • 0032506273 scopus 로고    scopus 로고
    • Mechanism of action of fibrates on lipid and lipoprotein metabolism
    • Staels B, Dallongeville J, Auwerx J, et al. Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 1998; 98: 2088-93
    • (1998) Circulation , vol.98 , pp. 2088-2093
    • Staels, B.1    Dallongeville, J.2    Auwerx, J.3
  • 84
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-Alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Natl Med 2001: 7: 53-8
    • (2001) Natl Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3
  • 85
    • 0034705071 scopus 로고    scopus 로고
    • CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferatoractivated receptors
    • Chinetti G, Gbaguidi FG, Griglio S, et al. CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferatoractivated receptors. Circulation 2000; 101: 2411-7
    • (2000) Circulation , vol.101 , pp. 2411-2417
    • Chinetti, G.1    Gbaguidi, F.G.2    Griglio, S.3
  • 86
    • 0028071959 scopus 로고
    • The effects of fibrates on lipoprotein and hemostatic coronary risk factors
    • Schonfeld G. The effects of fibrates on lipoprotein and hemostatic coronary risk factors. Atherosclerosis 1994; 111: 161-74
    • (1994) Atherosclerosis , vol.111 , pp. 161-174
    • Schonfeld, G.1
  • 87
    • 0035072138 scopus 로고    scopus 로고
    • Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia
    • Jonkers IJ, De Man FH, van der Laarse A, et al. Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia. J Hypertens 2001; 19: 749-55
    • (2001) J Hypertens , vol.19 , pp. 749-755
    • Jonkers, I.J.1    De Man, F.H.2    Van Der Laarse, A.3
  • 88
    • 0030726787 scopus 로고    scopus 로고
    • Comparison of bezafibrate versus lovastatin for lowering plasma insulin, fibrinogen, and plasminogen activator inhibitor-1 concentrations in hyperlipemic heart transplant patients
    • Zambrana JL, Velasco F, Castro P, et al. Comparison of bezafibrate versus lovastatin for lowering plasma insulin, fibrinogen, and plasminogen activator inhibitor-1 concentrations in hyperlipemic heart transplant patients. Am J Cardiol 1997; 80: 836-40
    • (1997) Am J Cardiol , vol.80 , pp. 836-840
    • Zambrana, J.L.1    Velasco, F.2    Castro, P.3
  • 89
    • 0344224259 scopus 로고    scopus 로고
    • Uncoupling protein-3 mRNA levels are increased in white adipose tissue and skeletal muscle of bezafibrate-treated rats
    • Cabrero A, Llaverias G, Roglans N, et al. Uncoupling protein-3 mRNA levels are increased in white adipose tissue and skeletal muscle of bezafibrate-treated rats. Biochem Biophys Res Commun 1999; 260: 547-56
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 547-556
    • Cabrero, A.1    Llaverias, G.2    Roglans, N.3
  • 90
    • 0032076207 scopus 로고    scopus 로고
    • Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia
    • Durrington PN, Mackness MI, Bhatnagar D, et al. Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia. Atherosclerosis 1998; 138: 217-25
    • (1998) Atherosclerosis , vol.138 , pp. 217-225
    • Durrington, P.N.1    Mackness, M.I.2    Bhatnagar, D.3
  • 91
    • 0002154331 scopus 로고    scopus 로고
    • Lowering fibrinogen levels: Clinical update
    • BIP Study Group. Bezafibrate Infarction Prevention
    • Behar S. Lowering fibrinogen levels: clinical update. BIP Study Group. Bezafibrate Infarction Prevention. Blood Coagul Fibrinolysis 1999; 10: S41-3
    • (1999) Blood Coagul Fibrinolysis , vol.10
    • Behar, S.1
  • 92
    • 0030695967 scopus 로고    scopus 로고
    • Effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen in hyperlipidaemic patients
    • Kockx M, de Maat MP, Knipscheer HC, et al. Effects of gemfibrozil and ciprofibrate on plasma levels of tissue-type plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen in hyperlipidaemic patients. Thromb Haemost 1997; 78: 1167-72
    • (1997) Thromb Haemost , vol.78 , pp. 1167-1172
    • Kockx, M.1    De Maat, M.P.2    Knipscheer, H.C.3
  • 93
    • 84992885930 scopus 로고    scopus 로고
    • Comparison of the efficacy of atorvastatin and micronized fenofibrate in the treatment of mixed hyperlipidemia
    • Bairaktari ET, Tzallas CS, Tsimihodimos VK, et al. Comparison of the efficacy of atorvastatin and micronized fenofibrate in the treatment of mixed hyperlipidemia. J Cardiovasc Risk 1999; 6: 113-6
    • (1999) J Cardiovasc Risk , vol.6 , pp. 113-116
    • Bairaktari, E.T.1    Tzallas, C.S.2    Tsimihodimos, V.K.3
  • 94
    • 0033134791 scopus 로고    scopus 로고
    • Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-Activated receptor-alpha
    • Kockx M, Gervois PP, Poulain P, et al. Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha. Blood 1999; 93: 2991-8
    • (1999) Blood , vol.93 , pp. 2991-2998
    • Kockx, M.1    Gervois, P.P.2    Poulain, P.3
  • 95
    • 0029162878 scopus 로고
    • Improvement of fibrinolysis and plasma lipoprotein levels induced by gemfibrozil in hypertriglyceridemia
    • Avellone G, Di Garbo V, Cordova R, et al. Improvement of fibrinolysis and plasma lipoprotein levels induced by gemfibrozil in hypertriglyceridemia. Blood Coagul Fibrinolysis 1995; 6: 543-8
    • (1995) Blood Coagul Fibrinolysis , vol.6 , pp. 543-548
    • Avellone, G.1    Di Garbo, V.2    Cordova, R.3
  • 96
    • 0026714027 scopus 로고
    • Bezafibrate lowers plasma lipids, fibrinogen and platelet aggregability in hypertriglyceridaemia
    • Pazzucconi F, Mannucci L, Mussoni L, et al. Bezafibrate lowers plasma lipids, fibrinogen and platelet aggregability in hypertriglyceridaemia. Eur J Clin Pharmacol 1992; 43: 219-23
    • (1992) Eur J Clin Pharmacol , vol.43 , pp. 219-223
    • Pazzucconi, F.1    Mannucci, L.2    Mussoni, L.3
  • 97
    • 0032565868 scopus 로고    scopus 로고
    • Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PARgamma activators
    • Staels B, Koenig W, Habib A, et al. Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators. Nature 1998; 393: 790-3
    • (1998) Nature , vol.393 , pp. 790-793
    • Staels, B.1    Koenig, W.2    Habib, A.3
  • 98
    • 0031813989 scopus 로고    scopus 로고
    • Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb
    • Madej A, Okopien B, Kowalski J, et al. Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb. Int J Clin Pharmacol Ther 1998; 36: 345-9
    • (1998) Int J Clin Pharmacol Ther , vol.36 , pp. 345-349
    • Madej, A.1    Okopien, B.2    Kowalski, J.3
  • 99
    • 0033527569 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1
    • Delerive P, De Bosscher K, Besnard S, et al. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1. J Biol Chem 1999; 274: 32048-54
    • (1999) J Biol Chem , vol.274 , pp. 32048-32054
    • Delerive, P.1    De Bosscher, K.2    Besnard, S.3
  • 100
    • 0026494899 scopus 로고
    • Tolerability of fibric acids. Comparative data and biochemical bases
    • Sirtori CR, Calabresi L, Werba JP, et al. Tolerability of fibric acids. Comparative data and biochemical bases. Pharmacol Res 1992; 26: 243-60
    • (1992) Pharmacol Res , vol.26 , pp. 243-260
    • Sirtori, C.R.1    Calabresi, L.2    Werba, J.P.3
  • 101
    • 0023614165 scopus 로고
    • Effects of fibric acid derivatives on biliary lipid composition
    • Palmer RH. Effects of fibric acid derivatives on biliary lipid composition. Am J Med 1987; 83: 37-43
    • (1987) Am J Med , vol.83 , pp. 37-43
    • Palmer, R.H.1
  • 102
    • 0017807874 scopus 로고
    • Clofibrate therapy and gallstone induction
    • Bateson MC, Maclean D, Ross PE, et al. Clofibrate therapy and gallstone induction. Am J Dig Dis 1978; 23: 623-8
    • (1978) Am J Dig Dis , vol.23 , pp. 623-628
    • Bateson, M.C.1    Maclean, D.2    Ross, P.E.3
  • 103
    • 0017745917 scopus 로고
    • Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the coronary drug project
    • Gallbladder disease as a side effect of drugs influencing lipid metabolism. Experience in the Coronary Drug Project. N Engl J Med 1977; 296: 1185-90
    • (1977) N Engl J Med , vol.296 , pp. 1185-1190
  • 105
    • 0033578187 scopus 로고    scopus 로고
    • Serum homocysteine increases after therapy with fenofibrate or bezafibrate
    • Dierkes J, Westphal S, Luley C. Serum homocysteine increases after therapy with fenofibrate or bezafibrate. Lancet 1999; 354: 219-20
    • (1999) Lancet , vol.354 , pp. 219-220
    • Dierkes, J.1    Westphal, S.2    Luley, C.3
  • 106
    • 0033517483 scopus 로고    scopus 로고
    • Implication of fibrate therapy for homocysteine
    • Jonkers IJ, De Man FH, Onkenhout W, et al. Implication of fibrate therapy for homocysteine. Lancet 1999; 354: 1208
    • (1999) Lancet , vol.354 , pp. 1208
    • Jonkers, I.J.1    De Man, F.H.2    Onkenhout, W.3
  • 107
    • 0033958138 scopus 로고    scopus 로고
    • Fish oil and cardiovascular disease: Lipids and arterial function
    • Nestel PJ. Fish oil and cardiovascular disease: lipids and arterial function. Am J Clin Nutr 2000; 71: 228S-31
    • (2000) Am J Clin Nutr , vol.71
    • Nestel, P.J.1
  • 108
    • 0035895997 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor alpha is not rate limiting for the lipoprotein lowering action of fish oil
    • Dallongeville J, Bauge E, Tailleux A, et al. Peroxisome proliferator activated receptor alpha is not rate limiting for the lipoprotein lowering action of fish oil. J Biol Chem 2000; 276: 4634-9
    • (2000) J Biol Chem , vol.276 , pp. 4634-4639
    • Dallongeville, J.1    Bauge, E.2    Tailleux, A.3
  • 109
    • 0025744248 scopus 로고
    • Effects of dietary fish oil supplementation on platelet aggregability and platelet membrane fluidity in normolipemic subjects with and without high plasma Lp(a) concentrations
    • Malle E, Sattler W, Prenner E, et al. Effects of dietary fish oil supplementation on platelet aggregability and platelet membrane fluidity in normolipemic subjects with and without high plasma Lp(a) concentrations. Atherosclerosis 1991; 88: 193-201
    • (1991) Atherosclerosis , vol.88 , pp. 193-201
    • Malle, E.1    Sattler, W.2    Prenner, E.3
  • 110
    • 0024427839 scopus 로고
    • Dietary supplementation with low-dose fish oils lowers fibrinogen levels: A randomized, double-blind controlled study
    • Radack K, Deck C, Huster G. Dietary supplementation with low-dose fish oils lowers fibrinogen levels: a randomized, double-blind controlled study. Ann Intern Med 1989; 111: 757-8
    • (1989) Ann Intern Med , vol.111 , pp. 757-758
    • Radack, K.1    Deck, C.2    Huster, G.3
  • 111
    • 0024489402 scopus 로고
    • The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells
    • Endres S, Ghorbani R, Kelley VE, et al. The effect of dietary supplementation with n-3 polyunsaturated fatty acids on the synthesis of interleukin-1 and tumor necrosis factor by mononuclear cells. N Engl J Med 1989; 320: 265-71
    • (1989) N Engl J Med , vol.320 , pp. 265-271
    • Endres, S.1    Ghorbani, R.2    Kelley, V.E.3
  • 112
    • 0024582271 scopus 로고
    • The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension
    • Knapp HR, FitzGerald GA. The antihypertensive effects of fish oil. A controlled study of polyunsaturated fatty acid supplements in essential hypertension. N Engl J Med 1989; 320: 1037-43
    • (1989) N Engl J Med , vol.320 , pp. 1037-1043
    • Knapp, H.R.1    Fitzgerald, G.A.2
  • 113
    • 0025308724 scopus 로고
    • Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study
    • Bonaa KH, Bjerve KS, Straume B, et al. Effect of eicosapentaenoic and docosahexaenoic acids on blood pressure in hypertension. A population-based intervention trial from the Tromso study. N Engl J Med 1990; 322: 795-801
    • (1990) N Engl J Med , vol.322 , pp. 795-801
    • Bonaa, K.H.1    Bjerve, K.S.2    Straume, B.3
  • 114
    • 0034006247 scopus 로고    scopus 로고
    • Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia
    • Goodfellow J, Bellamy MF, Ramsey MW, et al. Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol 2000; 35: 265-70
    • (2000) J Am Coll Cardiol , vol.35 , pp. 265-270
    • Goodfellow, J.1    Bellamy, M.F.2    Ramsey, M.W.3
  • 115
    • 0030938197 scopus 로고    scopus 로고
    • N-3 fatty acids do not lead to an increased diabetic risk in patients with hyperlipidemia and abnormal glucose tolerance
    • Italian Fish Oil Multicenter Study
    • Sirtori CR, Paoletti R, Mancini M, et al. N-3 fatty acids do not lead to an increased diabetic risk in patients with hyperlipidemia and abnormal glucose tolerance. Italian Fish Oil Multicenter Study. Am J Clin Nutr 1997; 65: 1874-81
    • (1997) Am J Clin Nutr , vol.65 , pp. 1874-1881
    • Sirtori, C.R.1    Paoletti, R.2    Mancini, M.3
  • 116
    • 0024428997 scopus 로고
    • Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM
    • Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989; 38: 1314-9
    • (1989) Diabetes , vol.38 , pp. 1314-1319
    • Borkman, M.1    Chisholm, D.J.2    Furler, S.M.3
  • 117
    • 0035059130 scopus 로고    scopus 로고
    • Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate
    • Higdon JV, Du SH, Lee YS, et al. Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. J Lipid Res 2001; 42: 407-18
    • (2001) J Lipid Res , vol.42 , pp. 407-418
    • Higdon, J.V.1    Du, S.H.2    Lee, Y.S.3
  • 118
    • 0029736881 scopus 로고    scopus 로고
    • Effects of fish oil on oxidation resistance of VLDL in hypertriglyceridemic patients
    • Hau MF, Smelt AH, Bindels AJ, et al. Effects of fish oil on oxidation resistance of VLDL in hypertriglyceridemic patients. Arterioscler Thromb Vasc Biol 1996; 16: 1197-202
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 1197-1202
    • Hau, M.F.1    Smelt, A.H.2    Bindels, A.J.3
  • 119
    • 0033966347 scopus 로고    scopus 로고
    • Safety considerations of polyunsaturated fatty acids
    • Eritsland J. Safety considerations of polyunsaturated fatty acids. Am J Clin Nutr 2000; 71: 197S-201
    • (2000) Am J Clin Nutr , vol.71
    • Eritsland, J.1
  • 121
    • 0032568084 scopus 로고    scopus 로고
    • Effects of statins on triglyceride metabolism
    • Ginsberg HN. Effects of statins on triglyceride metabolism. Am J Cardiol 1998; 81: 32B-5
    • (1998) Am J Cardiol , vol.81
    • Ginsberg, H.N.1
  • 122
    • 0035089758 scopus 로고    scopus 로고
    • Comparative study of HMG-CoA reductase inhibitors on fibrinogen
    • Rosenson RS, Tangney CC, Schaefer EJ. Comparative study of HMG-CoA reductase inhibitors on fibrinogen. Atherosclerosis 2001; 155: 463-6
    • (2001) Atherosclerosis , vol.155 , pp. 463-466
    • Rosenson, R.S.1    Tangney, C.C.2    Schaefer, E.J.3
  • 123
    • 0033958757 scopus 로고    scopus 로고
    • Effect of atorvastatin on hemorheologichemostatic parameters and serum fibrinogen levels in hyperlipidemic patients
    • Dujovne CA, Harris WS, Altman R, et al. Effect of atorvastatin on hemorheologichemostatic parameters and serum fibrinogen levels in hyperlipidemic patients. Am J Cardiol 2000; 85: 350-3
    • (2000) Am J Cardiol , vol.85 , pp. 350-353
    • Dujovne, C.A.1    Harris, W.S.2    Altman, R.3
  • 124
    • 0033201885 scopus 로고    scopus 로고
    • Post-prandial effects of gemfibrozil vs simvastatin in hypercholesterolemic subjects with borderline hypertriglyceridemia
    • Vigna GB, Donega P, Passaro A, et al. Post-prandial effects of gemfibrozil vs simvastatin in hypercholesterolemic subjects with borderline hypertriglyceridemia. Nutr Metab Cardiovasc Dis 1999; 9: 234-43
    • (1999) Nutr Metab Cardiovasc Dis , vol.9 , pp. 234-243
    • Vigna, G.B.1    Donega, P.2    Passaro, A.3
  • 125
    • 0035814945 scopus 로고    scopus 로고
    • Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia
    • Ridker PM, Rifai N, Lowenthal SP. Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia. Circulation 2001; 103: 1191-3
    • (2001) Circulation , vol.103 , pp. 1191-1193
    • Ridker, P.M.1    Rifai, N.2    Lowenthal, S.P.3
  • 126
    • 0033587667 scopus 로고    scopus 로고
    • Long-term effects of pravastatin on plasma concentration of C-reactive protein
    • The Cholesterol and Recurrent Events (CARE) Investigators
    • Ridker PM, Rifai N, Pfeffer MA, et al. Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators. Circulation 1999; 100: 230-5
    • (1999) Circulation , vol.100 , pp. 230-235
    • Ridker, P.M.1    Rifai, N.2    Pfeffer, M.A.3
  • 127
    • 0033586472 scopus 로고    scopus 로고
    • Inhibition of proinflammatory cytokine production by pravastatin
    • Rosenson RS, Tangney CC, Casey LC. Inhibition of proinflammatory cytokine production by pravastatin. Lancet 1999; 353: 983-4
    • (1999) Lancet , vol.353 , pp. 983-984
    • Rosenson, R.S.1    Tangney, C.C.2    Casey, L.C.3
  • 128
    • 15644376974 scopus 로고    scopus 로고
    • Pharmacological control of the mevalonate pathway: Effect on arterial smooth muscle cell proliferation
    • Raiteri M, Arnaboldi L, McGeady P, et al. Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation. J Pharmacol Exp Ther 1997; 281: 1144-53
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 1144-1153
    • Raiteri, M.1    Arnaboldi, L.2    McGeady, P.3
  • 129
    • 0026082759 scopus 로고
    • Vastatins inhibit cholesterol ester accumulation in human monocyte-derived macrophages
    • Kempen HJ, Vermeer M, de Wit E, et al. Vastatins inhibit cholesterol ester accumulation in human monocyte-derived macrophages. Arterioscler Thromb 1991; 11: 146-53
    • (1991) Arterioscler Thromb , vol.11 , pp. 146-153
    • Kempen, H.J.1    Vermeer, M.2    De Wit, E.3
  • 130
    • 0031775709 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors reduce MMP- 9 secretion by macrophages
    • Bellosta S, Via D, Canavesi M, et al. HMG-CoA reductase inhibitors reduce MMP- 9 secretion by macrophages. Arterioscler Thromb Vasc Biol 1998; 18: 1671-8
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1671-1678
    • Bellosta, S.1    Via, D.2    Canavesi, M.3
  • 131
    • 0035916233 scopus 로고    scopus 로고
    • Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: Implications for plaque stabilization
    • Crisby M, Nordin-Fredriksson G, Shah PK, et al. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-33
    • (2001) Circulation , vol.103 , pp. 926-933
    • Crisby, M.1    Nordin-Fredriksson, G.2    Shah, P.K.3
  • 132
    • 0034726386 scopus 로고    scopus 로고
    • Long-term safety of hepatic hydroxymethyl glutaryl coenzyme A reductase inhibitors: The role of metabolism-monograph for physicians
    • Bottorff M, Hansten P. Long-term safety of hepatic hydroxymethyl glutaryl coenzyme A reductase inhibitors: the role of metabolism-monograph for physicians. Arch Intern Med 2000; 160: 2273-80
    • (2000) Arch Intern Med , vol.160 , pp. 2273-2280
    • Bottorff, M.1    Hansten, P.2
  • 133
    • 0023232216 scopus 로고
    • Helsinki heart study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • Frick MH, Elo O, Haapa K, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317: 1237-45
    • (1987) N Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3
  • 134
    • 0023726344 scopus 로고
    • Lipid alterations and decline in the incidence of coronary heart disease in the helsinki heart study
    • Manninen V, Elo MO, Frick MH, et al. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. JAMA 1988; 260: 641-51
    • (1988) JAMA , vol.260 , pp. 641-651
    • Manninen, V.1    Elo, M.O.2    Frick, M.H.3
  • 135
    • 0029127208 scopus 로고
    • Some coronary risk factors related to the insulin resistance syndrome and treatment with gemfibrozil
    • Experience from the Helsinki Heart Study
    • Tenkanen L, Manttari M, Manninen V. Some coronary risk factors related to the insulin resistance syndrome and treatment with gemfibrozil. Experience from the Helsinki Heart Study. Circulation 1995; 92: 1779-85
    • (1995) Circulation , vol.92 , pp. 1779-1785
    • Tenkanen, L.1    Manttari, M.2    Manninen, V.3
  • 136
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans affairs high-density lipoprotein cholesterol intervention trial study group
    • Rubins HB, Robins SJ, Collins D, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans affairs high-density lipoprotein cholesterol intervention trial study group. N Engl J Med 1999; 341: 410-8
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 137
    • 0035962077 scopus 로고    scopus 로고
    • Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: A randomized controlled trial
    • Robins SJ, Collins D, Wittes JT, et al. Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial. JAMA 2001; 285: 1585-91
    • (2001) JAMA , vol.285 , pp. 1585-1591
    • Robins, S.J.1    Collins, D.2    Wittes, J.T.3
  • 138
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The bezafibrate infarction prevention (BIP) study
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: the Bezafibrate Infarction Prevention (BIP) study. Circulation 2000; 102: 21-7
    • (2000) Circulation , vol.102 , pp. 21-27


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