Hypertriglyceridemia and elevated lipoprotein(a) are risk factors for major coronary events in middle-aged men

American Journal of Cardiology

Volumn 77, Issue 14, 1996, Pages 1179-1184

  Assmann, Gerd ^a   Schulte, Helmut ^a   Von Eckardstein, Arnold ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTICLE; CORONARY ARTERY DISEASE; CORONARY RISK; FEMALE; HEART DEATH; HEART INFARCTION; HUMAN; HYPERTRIGLYCERIDEMIA; LIPOPROTEIN BLOOD LEVEL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RISK FACTOR; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0029884921     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(96)00159-2     Document Type: Article

References (30)

1. Lewis B, Assman G, Tikkanen M, Mancini M, Pometta D. Prevention of coronary heart disease: scientific background and new clinical guidelines. Recommendations of the European Atherosclerosis Society, prepared by the International Task Force for Prevention of Coronary Heart Disease. Nutr Metab Cardiovasc Dis 1992;2:113-156.
2. NIH Consensus Development Panel on Triglyceride, High Density Lipoprotein, and Coronary Heart Disease. JAMA 1993;269:505-510.
3. Hodis HN, Mack WN. Triglyceride-rich lipoproteins and the progression of coronary artery disease. Curr Opin Lipidol 1995;6:209-214.
4. Rader D, Hoeg JM, Brewer HB Jr. Quantitation of plasma apolipoproteins in the primary and secondary prevention of coronary artery disease. Ann Intern Med 1994;120:1012-1025.
5. Maher VMG, Brown BG. Lipoprotein(a) and coronary heart disease. Curr Opin Lipidol 1995;6:229-235.
6. Mahley RW, Rall SC Jr. Type III hyperlipoproteinemia (dysbetalipoproteinemia): the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Basis of Inherited Disease. 7th ed. New York: McGraw-Hill, 1995:1953-1980.
7. Rapp JH, Lespine A, Hamilton RL, Colyvas N, Chaumeton AH, Tweedie-Hardman J, Kotite L, Kunitake ST, Havel RJ, Kane JP. Triglyceride-rich lipoproteins isolated by selected-affinity anti-apolipoprotein B immunosorption from human atherosclerotic plaque. Arterioscler Thromb 1994;14:1767-1774.
8. Utermann G. Lipoprotein (a). In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Basis of Inherited Disease. 7th ed. New York: McGraw-Hill, 1995:1887-1912.
9. Grainger DJ, Grainger JC. Transforming growth factor-beta: the key to understanding lipoprotein(a). Curr Opin Lipidol 1995;6:81-85.
10. Jauhiainen M, Koskinen P, Ehnholm C, Heikki Frick M, Manttari M, Manninen V, Huttunen JK. Lipoprotein (a) and coronary heart disease risk: a nested case-control study of the Helsinki Heart Study participants. Atherosclerosis 1991;89:59-67.
11. Ridker PM, Hennekens CH, Stampfer MJ. A prospective study of lipoprotein(a) and the risk of myocardial infarction. JAMA 1993;270:2195-2199.
12. Assmann G, Schulte H. Results and conclusions of the Prospective Cardiovascular Münster (PROCAM) Study. In: Assmann G, ed. Lipid Metabolism Disorders and Coronary Heart Disease. 2nd ed. München: MMV Medizin Verlag, 1993:19-68.
13. Assmann G, Schulte H. Relation of high density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Am J Cardiol 1992;70:733-737.
14. Schriewer H, Assmann G, Sandkamp M, Schulte H. The relationship of lipoprotein (a) to risk factors of coronary heart disease. J Clin Chem Clin Biochem 1984;22:591-596.
15. Friedewald WT, Levy J, Fredrickson DS. Estimation of the concentration of low-density-lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-509.
16. Sandkamp M, Funke H, Schulte H, Köhler E, Assmann G. Lipoprotein(a) is an independent risk factor for myocardial infarction at a young age. Clin Chem 1990;38:20-25.
17. Nie NH. SPSSX User's Guide. New York: McGraw-Hill, 1983.
18. Ray AA. SAS User's Guide: Basics. Cary, NC: SAS Institute, 1982.
19. Benfante RJ, Reed DM, MacLean CJ, Yano K. Risk factors in middle age that predict early and late onset of coronary heart disease. J Clin Epidemiol 1989;42:95-104.
20. Criqui MH, Heiss G, Cohn R, Cowan LD, Suchindran CM, Bangdiwala S, Kritchevsky S, Jacobs DR, O'Grady HK, Davis CE. Plasma triglyceride level and mortality from coronary heart disease. N Engl J Med 1993;328:1220-1225.
21. Manninen V, Tenkanen L, Koskinen P, Huttunen JK, Mänttäri M, Heinonen OP, Frick MH. Joint effects of serum triglycerides and LDL-cholesterol and HDL-cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study - implications for treatment. Circulation 1992;85:37-45.
22. Laws A, King AC, Haskell WL, Reaven GM. Relation of fasting plasma insulin concentration to high density lipoprotein cholesterol and triglycerides in men. Arterioscler Thromb 1991;11:1636-1642.
23. Austin MA, Breslow JL, Hennekens CH, Buring JE, Willett WC, Krauss RM. Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA 1988;260:1917-1921.
24. Gough SCL, Juhan-Vague I. Insulin resistance and alterations in the fibrinolytic system. Cardiovasc Risk Factors 1993;3:387-396.
25. Sigurdsson G, Baldursdottir A, Sigvaldason H, Agnarsson U, Thorgeirsson G, Sigfusson N. Predictive value of apolipoproteins in a prospective survey of coronary artery disease in men. Am J Cardiol 1992;69:1251-1254.
26. Cremer P, Nagel D, Mann H, Muche R, Elster H, Seidel D. Lipoprotein Lp(a) as predictor of myocardial infarction in comparison to fibrinogen, LDL-cholesterol and other risk factors: results from the Göttingen Risk Incidence and Prevalence Study (GRIPS). Eur J Clin Invest 1994;24:444-453.
27. Schaefer EJ, Lamon-Fava S, Jenner JL, McNamara JR, Ordovas JM, Davis CE, Abolafia JM, Lippel K, Levy RI. Lipoprotein(a) levels and risk of coronary heart disease in men: the Lipid Research Clinics Coronary Primary Prevention Trial. JAMA 1993;27:999-1003.
28. Wald NJ, Law M, Watt HC, Wu T, Bailey A, Johnson AM, Craig WY, Ledue TBA, Haddow JE. Apolipoproteins and ischaemic heart disease: implications for screening. Lancet 1994;343:75-79.
29. Sgoutas DS, Turen T. Effect of freezing and thawing on the immunoassay of lipoprotein (a). Clin Chem 1992;38:1873-1877.
30. Craig WY, Poulin SE, Forster NR, Neveux LM, Wald NJ, Ledue TB. Effect of sample storage on the assay of lipoprotein(a) by commercially available radial immunodiffusion and enzyme-linked immunosorbent assay kits. Clin Chem 1992;38:550-553.