Arthropod 5-HT2 Receptors: A Neurohormonal Receptor in Decapod Crustaceans That Displays Agonist Independent Activity Resulting from an Evolutionary Alteration to the DRY Motif

Journal of Neuroscience

Volumn 24, Issue 13, 2004, Pages 3421-3435

  Clark, Merry C ^a   Dever, Timothy E ^a   Dever, John J ^a   Xu, Ping ^a   Rehder, Vincent ^a   Sosa, Maria A ^b,c   Baro, Deborah J ^a,b,c  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PUERTO RICO MEDICAL SCIENCES CAMPUS   (Puerto Rico)

^c UNIVERSITY OF PUERTO RICO SCHOOL OF MEDICINE   (Puerto Rico)

Author keywords

cAMP; Constitutive; CPG; Gq; GPCR; Immunocytochemistry; IP3; Monoamine; Motor pattern; Neuromodulator; Panulirus interruptus; PKC; PLC; Serotonin; Signal transduction; STG; Stomatogastric

Indexed keywords

SEROTONIN 2 RECEPTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; BIOGENIC AMINE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; NEUROTRANSMITTER RECEPTOR; PHOSPHOLIPASE C; PROTEIN KINASE C;

ARTHROPOD; ARTICLE; BIOINFORMATICS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DECAPODA (CRUSTACEA); DROSOPHILA; DRY MOTIF; ELECTROPHYSIOLOGY; EMBRYO; EVOLUTION; HUMAN; HUMAN CELL; INSECT; LOBSTER; MEMBRANE POTENTIAL; MOLECULAR CLONING; MONOAMINERGIC SYSTEM; NERVE CELL NETWORK; NEURITE; NEUROMUSCULAR SYNAPSE; NEUROPIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PANULIRUS INTERRUPTUS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; BIOLOGY; CELL LINE; COMPARATIVE STUDY; DIGESTIVE SYSTEM; DRUG EFFECT; DRUG POTENTIATION; GENETICS; INNERVATION; METABOLISM; METHODOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PALINURIDAE; PHYSIOLOGY; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BIOGENIC AMINES; CELL LINE; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DIGESTIVE SYSTEM; DROSOPHILA; EVOLUTION, MOLECULAR; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NERVE NET; NEUROTRANSMITTER AGENTS; PALINURIDAE; PHOSPHOLIPASE C; PROTEIN KINASE C; RECEPTORS, NEUROTRANSMITTER; RECEPTORS, SEROTONIN, 5-HT2; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1842506441     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0062-04.2004     Document Type: Article

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