Mapping the binding site pocket of the serotonin 5-hydroxytryptamine2A receptor: Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin

Journal of Biological Chemistry

Volumn 271, Issue 25, 1996, Pages 14672-14675

  Almaula, Niva ^a   Ebersole, Barbara J ^a   Zhang, Daqun ^a   Weinstein, Harel ^a   Sealfon, Stuart C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN 2A RECEPTOR;

ARTICLE; BINDING SITE; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; NEUROTRANSMISSION; PRIORITY JOURNAL; SEROTONINERGIC NERVE CELL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BUFOTENIN; CELL LINE; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COMPUTER SIMULATION; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHATIDYLINOSITOLS; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SERINE; SEROTONIN; TRANSFECTION;

EID: 0029886215     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.25.14672     Document Type: Article

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