Cyclin E2, the cycle continues

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 4, 2002, Pages 315-320

  Payton, Marc ^a   Coats, Steve ^a  

^a AMGEN INC   (United States)

Author keywords

CDK2; Cyclin E; Cyclin E2

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE E; DNA; ISOPROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; EUKARYOTIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PHASE TRANSITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REDUNDANCY ANALYSIS; REGULATORY MECHANISM; TUMOR;

EUKARYOTA;

EID: 0036169275     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(01)00137-6     Document Type: Short Survey

References (27)

1. Evolving ideas about cyclins
2. 1 phase progression
3. Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family
4. 1 cyclin (Cln) function in yeast
5. Rescue of cyclin D1 deficiency by knockin cyclin E
6. Derugulated cyclin E induces chromosome instability
7. Cyclin E in human cancers
8. Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E
9. Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubitquitin-dependent degradation of cyclin E
10. Turnover of cyclin E by the ubiquitin-proteasome pathway is regualted by CDK2 binding and cyclin phosphorylation
11. A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
12. Cyclin E, a potential prognostic marker for breast cancer
13. Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer
14. 1 cyclin that binds CDK2 and is aberrantly expressed in human cancers
15. 1 cyclin and activating partner of CDK2 and 3, is induced by viral oncoproteins
16. 1 and S phases of the mammalian cell cycle
17. 1-S transition
18. 1 to S transition
19. Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein
20. Interactions of the human papillomavirus E7 protein
21. 1/S phase transition by expression of cyclin D1 and E with an inducible system
22. Over-expression of cyclin A advances entry into S phase
23. Cancer cell cycle
24. Expression of cell cycle regulators p27 and cyclin E alone and in combination, correlate with survival in young breast cancer patients
25. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
26. Decreased levels of the cell-cycle inhibitor p27(Kip1) protein: Prognostic implications in primary breast cancer
27. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts