The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells

AIDS

Volumn 10, Issue 1, 1996, Pages 9-16

  Gehri, Roland ^a   Hahn, Sinuhe ^a   Rothen, Madeleine ^a   Steuerwald, Michael ^b   Nuesch, Reto ^b   Erb, Peter ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

CD28; Cytotoxic T lymphocytes; Fas

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; FAS ANTIGEN;

ARTICLE; CONTROLLED STUDY; CYTOFLUOROMETRY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE DEPLETION; MAJOR CLINICAL STUDY; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; T LYMPHOCYTE; TARGET CELL;

EID: 9044232148     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199601000-00002     Document Type: Article

References (55)

1. Wei XP, Ghosh SK, Taylor ME, et al.: Viral dynamics in human immunodeficiency virus type 1 infection. Nature 1995, 373:117-122.
2. Ho DD, Neumann AU, Perelson AS, Chen W, Leonard JM, Markowitz M: Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995, 373:123-126.
3. Gruters RA, Miedema F: Lymphocyte-T functional defects in HIV infection. In Immunodeficiency in HIV Infection and AIDS. Edited by Janossy G, Autran B, Miedema F. Windsor; 1992:135-144. 144.
4. Landay AL, Mackewicz CE, Levy JA: An activated CD8+ T-Cell phenotype correlates with anti-HIV activity and asymptomatic clinical status. Clin Immunol Immunopathol 1993, 69:106-116.
5. Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB: Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994, 68:6103-6110.
6. Cao YZ, Qin LM, Zhang LQ, Safrit J, Ho DD: Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection. N Engl J Med 1995, 332:201-208.
7. Pantaleo G, Menzo S, Vaccarezza M, et al.: Studies in subjects with long term nonprogressive human immuno-deficiency virus infection. N Engl J Med 1995, 332:209-216.
8. Ameisen JC: Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer. AIDS 1994, 8:1197-1213.
9. Finkel TH, Tudor-Williams G, Banda NK, et al.: Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nature Med 1995, 1:129-134.
10. Itoh N, Yonehara S, Ishii A, et al.: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991, 66:223-243.
11. Watanabe-Fukunaga R, Brannan CI, Itoh N, et al.: The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 1992, 148:1274-1279.
12. Oehm A, Behrmann I, Falk W, et al.: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J Biol Chem 1992, 267:10709-10715.
13. Miyawaki T, Uehara T, Nibu R, et al.: Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 1992, 149:3753-3758.
14. Owenschaub LB, Yonehara S, Crump WL, Grimm EA: DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement. Cell Immunol 1992, 140:197-205.
15. Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 1989, 169:1747-1756.
16. Trauth BC, Klas C, Peters AMJ, et al.: Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989, 245:301-300.
17. Dhein J, Daniel PT, Trauth BC, Oehm A, Moller P, Krammer PH: Induction of apoptosis by monoclonal antibody anti-APO-1 class switch variants is dependent on cross-linking of APO-1 cell surface antigens. J Immunol 1992, 149:3166-3173.
18. Suda T, Takahashi T, Golstein P, Nagata S: Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993, 75:1169-1178.
19. Kobayashi N, Hamamoto Y, Yamamoto N, Yonehara M, Yonehara S: Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication. Proc Natl Acad Sci USA 1990, 87:9620-9624.
20. Debatin KM, Fahrig Faissner A, Enenkel Stoodt S, Kreuz W, Benner A, Krammer PH: High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children [letter]. Blood 1994, 83:3101-3103.
21. Katsikis PD, Wunderlich ES, Smith CA, Herzenberg LA: Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J Exp Med 1995, 181:2029-2036.
22. Lowenthal JW, Castle BE, Christiansen J, et al.: Expression of high affinity receptors for murine interleukin 4 (BSF-1) on hemopoietic and nonhemopoietic cells. J Immunol 1988, 140:456-464.
23. Centers for Disease Control and Prevention: Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR 1993, 41:1-19.
24. Stalder T, Hahn SH, Erb P: Fas antigen is the major target molecule for CD4+ T-cell-mediated cytotoxicity. J Immunol 1994, 152:1127-1133.
25. Erb P, Troxler M, Fluri M, Grogg D, Alkan SS: Functional heterogeneity of CD4-positive T-cell subsets - the correlation between effector functions and lymphokine secretion is limited. Cell Immunol 1991, 135:232-244.
26. Erb P, Grogg D, Troxler M, Kennedy M, Fluri M: CD4+ T cell-mediated killing of MHC class II-positive antigen-presenting cells. I. Characterization of target cell recognition by in vivo or in vitro activated CD4+ killer T cells. J Immunol 1990, 144:790-795.
27. Alderson MR, Armitage RJ, Maraskovsky E, et al.: Fas transduces activation signals in normal human T-lymphocytes. J Exp Med 1993, 178:2231-2235.
28. Hahn S, Gehri R, Erb P: Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev 1995, 146:57-79.
29. Suda T, Okazaki T, Naito Y, et al.: Expression of the fas ligand in cells of T cell lineage. J Immunol 1995, 154:3806-3813.
30. Gruters RA, Terpstra FG, De Goede REY, et al.: Immunological and virological markers in individuals progressing from seroconversion to AIDS. AIDS 1991, 5:837-844.
31. Saukonnen JJ, Kornfeld H, Berman JS: Expansion of a CD8+ CD28- cell population in the blood and lung of HIV-positive patients. J Acquir Immune Defic Syndr 1993, 6:1194-1204.
32. Borthwick NJ, Bofill M, Gombert WM, et al.: Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells. AIDS 1994, 8:431-441.
33. Brinchmann JE, Dobloug JH, Heger BH, Haaheim LL, Sannes M, Egeland T: Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations. J Infect Dis 1994, 169:730-738.
34. Caruso A, Cantalamessa A, Licenziati S, et al.: Expression of CD28 on CD8(+) and CD4(+) lymphocytes during HIV infection. Scand J Immunol 1994, 40:485-490.
35. Azuma M, Phillips JH, Lanier LL: CD28-lymphocytes T: antigenic and functional properties. J Immunol 1993, 150:1147-1159.
36. Linsley PS, Ledbetter JA: The role of the CD28 receptor during T-cell responses to antigen. Annu Rev Immunol 1993, 11:191-212.
37. Azuma M, Cayabyab M, Buck D, Phillips JH, Lanier LL: CD28 interaction with B7-costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting lymphocytes-T. J Exp Med 1992, 175:353-360.
38. Fleischer B: CD26: a surface protease involved in T-cell activation. Immunol Today 1994, 15:180-184.
39. Callebaut C, Krust B, Jacotot E, Hovanessian AC: T cell activation antigen, CD26, as a cofactor for entry of HIV in CD4+ cells. Science 1993, 262:2045-2050.
40. Werner A, Mattern T, Ulmer AJ, Flad HD, Kurth R, Baier M: CD26 is not required for infection of the lymphoma cell line C8166 with HIV-1 [letter]. AIDS 1994, 8:1348-1349.
41. West WHL, Stott EJ: Cell surface expression of CD26 does not correlate with susceptibility to immunodeficiency viruses [letter]. AIDS 1994, 8:1349-1350.
42. Blazquez MV, Madueno JA, Gonzalez R, et al.: Selective decrease of CD26 expression in T cells from HIV-1 infected individuals. J Immunol 1992, 149:3073-3077.
43. Akbar AN, Salmon M, Janossy C: The synergy between naive and memory T-cells during activation. Immunol Today 1991, 12:184-188.
44. Froebel KS, Doherty KV, Whitelaw JA, Hague RA, Mok JY, Bird AG: Increased expression of the CD45RO (memory) antigen on T-cells in HIV-infected children. AIDS 1991, 5:97-99.
45. van Noesel CJM, Gruters RA, Terpstra FG, Schellekens PThA, Van Lier RAW, Miedema F: Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men. J Clin Invest 1990, 86:293-299.
46. Janossy G, Borthwick N, Lomnitzer R, et al.: Lymphocyte activation in HIV-1 infection. 1. Predominant proliferative defects among CD45RO+ cells of the CD4 and CD8 lineages. AIDS 1993, 7:613-624.
47. Kabelitz D, Pohl T, Pechhold K: Activation-induced cell death (apoptosis) of mature peripheral T-lymphocytes. Immunol Today 1993, 14:338-339.
48. Sieling PA, Wang XH, Gately MK, et al.: IL-12 regulates T helper type 1 cytokine responses in human infectious disease. J Immunol 1994, 153:3639-3647.
49. Dhein J, Walczak H, Bäumler C, Debatin KM, Krammer PH: Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 1995, 373:438-441.
50. Brunner T, Mogil RJ, LaFace D, et al.: Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995, 373:441-444.
51. Ju S-T, Panka DJ, Cui H, et al.: Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995, 373:444-448.
52. Mapara MY, Bargou R, Zugck C, et al.: APO-1 mediated apoptosis or proliferation in human chronic B-lymphocytic leukemia - correlation with bcl-2 oncogene expression. Eur J Immunol 1993, 23:702-708.
53. Li CJ, Friedman DJ, Wang C, Metelev V, Pardee AB: Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 1995, 268:429-431.
54. Westendorp MO, Frank K, Ochsenbauer C, et al.: Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 1995, 375:497-500.
55. Gutheil WG, Subramanyam M, Flentke GR, et al.: Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): A possible mechanism for Tat's immunosuppressive activity. Proc Natl Acad Sci USA 1994, 91:6594-6598.