Role of the Fas/Fas ligand apoptotic pathway in human immunodeficiency virus type 1 disease

Journal of Virology

Volumn 72, Issue 8, 1998, Pages 6279-6282

  Kaplan, David ^a   Sieg, Scott ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; FAS LIGAND;

APOPTOSIS; CELL DEATH; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOLOGY; LYMPHOCYTE DEPLETION; PRIORITY JOURNAL; REGULATORY MECHANISM; SHORT SURVEY; T LYMPHOCYTE SUBPOPULATION;

EID: 0031903406     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.8.6279-6282.1998     Document Type: Short Survey

References (69)

1. Alderson, M., T. Tough, T. Davis-Smith, S. Braddy, B. Falk, K. Schooley, R. Goodwin, C. Smith, F. Ramsdell, and D. Lynch. 1995. Fas ligand mediates activation-induced cell death in human T lymphocytes. J. Exp. Med. 181:71-77.
2. Ameisen, J. C., and A. Capron. 1991. Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis. Immunol. Today 12:102-105.
3. Andersson, M., A. McMichael, and P. A. Peterson. 1987. Reduced allorecognition of adenovirus-2 infected cells. J. Immunol. 138:3960-3966.
4. Antoni, B., P. Sabbatini, A. Rabson, and E. White. 1995. Inhibition of apoptosis in HIV-infected cells enhances virus production and facilitates persistent infection. J. Virol. 69:2384-2392.
5. Aries, S. P., B. Schaaf, C. Muller, R. H. Dennin, and K. Dalhoff. 1995. Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression. J. Mol. Med. 73:591-593.
6. Ayyavoo, V., A. Mahboubi, S. Mahalingam, R. Ramalingam, S. Kudchodkar, W. V. Williams, D. R. Green, and D. B. Weiner. 1997. HIV-1 Vpr suppresses immune activation and apoptosis through regulation of nuclear factor kappa B. Nat. Med. 3:1117-1123.
7. Badley, A., J. McElhinny, P. Leibson, D. Lynch, M. Alderson, and C. Paya. 1996. Upregulation of Fas ligand expression by HIV in human macrophages mediates apoptosis of uninfected T lymphocytes. J. Virol. 70:199-206.
8. Bahr, G. M., A. Capron, J. Dewulf, S. Nagata, M. Tanaka, J. Bourez, and Y. Mouton. 1997. Elevated serum level of Fas ligand correlates with the asymptomatic stage of human immunodeficiency virus infection. Blood 90:896-898.
9. Banda, N., J. Bernier, D. Kurahara, R. Kurrle, N. Haigwood, R. Sekaly, and T. Finkel. 1992. Crosslinking CD4 by HIV gp120 primes T cells for activation induced apoptosis. J. Exp. Med. 176:1099-1106.
10. Baumler, C., T. Bohler, I. Herr, A. Benner, P. Krammer, and K. Debatin. 1996. Activation of the CD95 (APO-1/Fas) system in T cells from HIV-1-infected children. Blood 88:1741-1746.
11. Biswas, P., G. Poll, J. Orenstein, and A. S. Fauci. 1994. Cytokine-mediated induction of human immunodeficiency virus type 1 (HIV-1) expression and cell death in chronically infected U1 cells: do TNF alpha and gamma interferon selectively kill HIV-1-intected cells? J. Virol. 68:2598-2604.
12. Brunner, T., R. Mogil, D. LaFace, N. Yoo, A. Mahboubi, F. Echeverri, S. Martin, W. Force, D. Lynch, C. Ware, and D. Green. 1995 Cell-autonomous Fas/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 373:441-444.
13. Chinnaiyan, A., C. Woffendin, V. Dixit, and G. Nabel. 1997. The inhibition of pro-apoptotic ICE-like proteases enhances HIV-1 replication. Nat. Med. 3:333-337.
14. Clem, R. J., M. Fechheimer, and L. K. Miller. 1991. Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 254:1388-1390.
15. Crook, N. E., R. J. Clem, and L. K. Miller. 1993. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J. Virol. 67:2168-2174.
16. Debatin, K., A. Faissner, S. Stoodt, W. Dreuz, A. Benner, and P. Krammer. 1994. High expression of APO-1 (CD95) on T lymphocytes from HIV-1-infected children. Blood 83:3101-3103.
17. Debbas, M., and E. White. 1993. Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B. Genes Dev. 71:546-554.
18. Dhein, J., H. Walczak, C. Baumler, K. Debatin, and P. Krammer. 1995. Autocrine T-cell suicide mediated by APO-1(Fas/CD95). Nature 373:438-441.
19. Dobbelstein, M., and T. Shenk. 1996. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product. J. Virol. 70:6479-6485.
20. Estaquier, J., M. Tanaka, T. Suda, S. Nagata, P. Golstein, and J. Amiesen. 1996. Fas-mediated apoptosis of CD4+ and CD8+ T cells from HIV-1-infected persons: differential in vitro preventive effect of cytokines and protease antagonists. Blood 87:4959-4966.
21. Finkel, T., G. Tudor-Williams, N. Banda, M. Cotton, T. Curriel, C. Monks, T. Baba, R. Rubrecht, and A. Kuppfer. 1995. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1:129-134.
22. Gehri, R., S. Hahn, M. Rothen, M. Steuerwald, R. Nuesch, and P. Erb. 1996. The Fas receptor in HIV infection: expression on peripheral blood lymphocytes and role in the depletion of T cells. AIDS 10:9-16.
23. Groux, H., G. Torpier, D. Monte, Y. Mouton, A. Capron, and J. C. Ameisen. 1992. Activation-induced death by apoptosis in CD4+ T cells from HIV-1-infected asymptomatic individuals. J. Exp. Med. 175:331-340.
24. Ju, S.-T., D. Panka, H. Cui, R. Ettinger, M. El-Khatib, D. Sherr, B. Stanger, and A. Marshak-Rothstein. 1995. Fas/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444-448.
25. Katsikis, P., E. Wunderlich, C. Smith, L. A. Herzenberg, and L. A. Herzenberg. 1995. Fas antigen stimulation induces marked apoptosis of T lymphocytes in HIV-1 infected individuals. J. Exp. Med. 181:2029-2036.
26. Katsikis, P. D., M. E. Garcia-Ojeda, J. F. Terres-Roca, I. M. Tijoe, C. A. Smith, L. A. Herzenberg, and L. A. Herzenberg. 1997. Interleukin-1β converting enzyme-like protease involvement in Fas-induced and activation-induced peripheral blood T cell apoptosis in HIV-1 infection. TNF-related apoptosis-inducing ligand can mediate activation-induced T cell death in HIV-1 infection. J. Exp. Med. 186:1365-1372.
27. Katsikis, P. D., M. Garcia-Ojeda, E. S. Wunderlich, C. Smith, H. Yagita, K. Okumura, N. Kayagaki, M. Alderson, L. A. Herzenberg, and L. A. Herzenberg. 1996. Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-1-infected individuals. Int. Immunol. 8:1311-1317.
28. Kibler, K. V., T. Shors, K. B. Perkins, C. Zeman, M. Banaszak, J. Biesterfeldt, J. Langland, and B. Jacobs. 1997. Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells. J. Virol. 71:1992-2003.
29. Klenerman, P., S. Rowland-Jones, S. McAdam, J. Edwards, S. Daenke, D. Lalloo, B. Koppe, W. Rosenberg, D. Boyd, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. 1994. Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants. Nature 369:403-407.
30. Kobayashi, N., Y. Hamamoto, N. Yamamoto, A. Ishii, M. Yonehara, and S. Yonehara. 1990. Anti-Fas monoclonal antibody is cytocidal to human immunodeficiency virus-infected cells without augmenting viral replication. Proc. Natl. Acad. Sci. USA 87:9620-9624.
31. Kolesnitchenko, V., L. King, A. Riva, Y. Tani, S. Korsmeyer, and D. Cohen. 1997. A major human immunodeficiency virus type 1-initiated killing pathway distinct from apoptosis. J. Virol. 71:9753-9763.
32. Laurent-Crawford, A., B. Krust, S. Muller, Y. Riviere, M. Rey-Cuille, J. Bechet, L. Montagnier, and A. Hovanessian. 1991. The cytopathic effect of HIV is associated with apoptosis. Virology 185:829-839.
33. Lee, S. B., and M. Esteban. 1994. The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199:491-496.
34. Li, C., D. Friedman, C. Wang, V. Metelev, and A. Pardee. 1995. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 268:429-431.
35. + cells expressing gp160 of human immunodeficiency virus type 1. J. Virol. 68:390-399.
36. Maldarelli, F., H. Sato, E. Berthold, J. Orenstein, and M. Martin. 1995. Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1. J. Virol. 69:6457-6465.
37. Marcellus, R. C., J. G. Teodoro, T. Wu, D. Brough, G. Keiner, G. C. Shore, and P. E. Branton. 1996. Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis. J. Virol. 70:6207-6215.
38. McCloskey, T. W., M. Ott, E. Tribble, S. Khan, S. Teichberg, M. O. Paul, S. Pahwa, E. Verdin, and N. Chirmule. 1997. Dual role of HIV Tat in regulation of apoptosis in T cells. J. Immunol. 158:1014-1019.
39. Meyaard, L., S. A. Otto, R. R. Jonker, M. J. Mynster, R. P. M. Keet, and F. Miedema. 1992. Programmed death of T cells in HIV-1 infection. Science 257:217-219.
40. Meyaard, L., S. A. Otto, I. P. M. Keet, M. T. L. Roos, and F. Miedema. 1994. Programmed death of T cells in HIV infection. No correlation with progression to disease. J. Clin. Invest. 93:982-988.
41. Mitra, D., M. Steiner, D. H. Lynch, L. Staiano-Coico, and J. Laurence. 1996. HIV-1 upregulates Fas ligand expression in CD4+ T cells in vitro and in vivo: association with Fas-mediated apoptosis and modulation by aurintricarboxylic acid. Immunology 87:581-585.
42. Muro-Cacho, C., G. Pantaleo, and A. Fauci. 1995. Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease of viral burden. J. Immunol. 154:5555-5566.
43. Oberg, H., R. Sanzenbacher, B. Lengl-Janssen, T. Dobmeyer, S. Flindt, O. Janssen, and D. Kabelitz. 1997. Ligation of cell surface CD4 inhibits activation-induced death of human T lymphocytes at the level of Fas ligand expression. J. Immunol. 159:5742-5749.
44. Planelles, V., F. Bachelerie, J. Jowett, A. Haislip, Y. Xie, P. Banooni, T. Masuda, and I. S. Y. Chen. 1995. Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for Vpr. J. Virol. 69:5883-5889.
45. Prikhod'ko, E. A., and L. K. Miller. 1996. Induction of apoptosis by baculovirus transactivator IE1. J. Virol. 70:7116-7124.
46. Purvis, S., J. Jacobberger, M. Sramkoski, A. Patki, and M. Lederman. 1995. HIV type 1 Tat protein induces apoptosis and death in Jurkat cells. AIDS Res. Hum. Retroviruses 4:443-450.
47. Razvi, E. S., and R. M. Welsh. 1995. Apoptosis in viral infections. Adv. Viral Res. 45:1-60.
48. Rothen, M., S. Gratzl, H. H. Hirsch, and C. Moroni. 1997. Apoptosis in HIV-1-infected individuals is an early marker occurring independently of high viremia. AIDS Res. Hum. Retroviruses 13:771-779.
49. Sandstrom, P., D. Pardi, C. Goldsmith, D. Chengying, A. Diamond, and T. Folks. 1996. Bcl-2 expression facilitates human immunodeficiency virus type 1-mediated cytopathic effects during acute spreading infections. J. Virol. 70:4617-4622.
50. Sieg, S., D. Smith, Z. Yildirim, and D. Kaplan. 1997. Fas ligand deficiency in HIV disease. Proc. Natl. Acad. Sci. USA 94:5860-5865.
51. Sieg, S., Z. Yildirim, D. Smith, N. Kayagaki, H. Yagita, Y. Huang, and D. Kaplan. 1996. Herpes simplex virus type 2 inhibition of Fas ligand expression. J. Virol. 70:8747-8751.
52. Silvestris, F., P. Cafforio, M. Frassanito, M. Tucci, A. Romito, S. Nagata, and F. Dammacco. 1996. Overexpression of Fas antigen on T cells in advanced HIV-1 infection: differential ligation constantly induces apoptosis. AIDS 10:131-141.
53. Sloand, E., N. Young, P. Kumar, F. Weichold, T. Sato, and J. Maciejewski. 1997. Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication. Blood 89:1357-1363.
54. Stewart, S., B. Poon, J. Jowett, and I. Chen. 1997. Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest. J. Virol. 71:5579-5592.
55. Suda, T., H. Hashimoto, M. Tanaka, T. Ochi, and S. Nagata. 1997. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J. Exp. Med. 186:2045-2050.
56. Sylwester, A., S. Murphy, D. Shutt, and D. Soil. 1997. HIV-1-induced T cell syncytia are self-perpetuating and the primary cause of T cell death in culture. J. Immunol. 158:3996-4007.
57. Takahashi, T., M. Tanaka, C. Brannan, N. Jenkins, N. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969-976.
58. Tanaka, M., T. Itai, M. Adachi, and S. Nagata. 1998. Downregulation of Fas ligand by shedding. Nat. Med. 4:31-36.
59. Teodoro, J. G., and P. E. Branton. 1997. Regulation of apoptosis by viral gene products. J. Virol. 71:1739-1746.
60. Terai, C., R. S. Kornbluth, C. D. Pauza, D. D. Richman, and D. A. Carson. 1991. Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J. Clin. Invest. 87:1710-1715.
61. Tollefson, A., A. Scaria, T. Hermiston, J. Ryerse, L. Wold, and W. Wold. 1996. The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells. J. Virol. 70:2296-2306.
62. Tolskaya, E., L. Romanova, M. Kolesnikova, T. Ivannikova, E. Smirnova, N. Raikhlin, and V. Agol. 1995. Apoptosis-inducing and apoptosis-preventing functions of poliovirus. J. Virol. 69:1181-1189.
63. Vaux, D. L., G. Haecker, and A. Strasser. 1994. An evolutionary perspective on apoptosis. Cell 76:777-779.
64. Vaux, D. L., and A. Strasser. 1996. The molecular biology of apoptosis. Proc. Natl. Acad. Sci. USA 93:2239-2344.
65. Westendorp, M., R. Frank, C. Ochsenbauer, K. Stricker, J. Dhein, H. Walczak, K. Debatin, and P. Krammer. 1995. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375:497-500.
66. Westendorp, M., V. Shatrov, K. Schulze-Osthoff, R. Frank, M. Kraft, M. Los, P. Krammer, W. Droge, and V. Lehmann. 1995. HIV-1 Tat potentiates TNF-induced NF-κB activation and cytotoxicity by altering the cellular redox state. EMBO J. 14:546-554.
67. Wold, W. S. M., and L. R. Gooding. 1991. Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions. Virology 184:1-8.
68. Xu, X., G. Screaton, F. Gotch, T. Dong, R. Tan, N. Almond, B. Walker, R. Stebbings, K. Kent, S. Nagata, J. Stott, and A. McMichael. 1997. Evasion of cytotoxic T lymphocyte (CTL) responses by Nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells. J. Exp. Med. 186:7-16.
69. Zauli, G., D. Gibellini, D. Milani, M. Mazzoni, P. Borgatti, M. La Placa, and S. Capitani. 1993. HIV-1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis. Cancer Res. 53:4481-4485.