C-terminus mutations of Acremonium chrysogenum deacetoxy/ deacetylcephalosporin C synthase with improved activity toward penicillin analogs

FEMS Microbiology Letters

Volumn 246, Issue 1, 2005, Pages 103-110

  Wu, Xiao Bin ^a,b   Fan, Ke Qiang ^a   Wang, Qin Hong ^a   Yang, Ke Qian ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Acremonium chrysogenum; C terminus; DAC; DAOC; Deacetoxy deacetylcephalosporin C synthase; Kinetics; Mutagenesis

Indexed keywords

AMOXICILLIN; AMPICILLIN; CARBENICILLIN; DEACETOXYCEPHALOSPORIN C; LEUCINE; PENICILLIN DERIVATIVE; PENICILLIN G; PENICILLIN V;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CATALYST; CEPHALOSPORIUM ACREMONIUM; COMPARATIVE STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; GENE MUTATION; HYDROXYLATION; KINETICS; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ACREMONIUM CHRYSOGENUM;

EID: 18144392681     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2005.03.043     Document Type: Article

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