Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS)

Journal of Molecular Biology

Volumn 308, Issue 5, 2001, Pages 937-948

  Lee, Hwei Jen ^a,b   Lloyd, Matthew D ^a   Harlos, Karl ^c   Clifton, Ian J ^a   Baldwin, Jack E ^a   Schofield, Christopher J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

C terminal truncation mutants; Cephem antibiotic biosynthesis; Control of uncoupled oxidation; Iron(II), 2 oxoglutarate dependent oxygenases

Indexed keywords

CEPHALOSPORIN DERIVATIVE; DEACETOXYCEPHALOSPORIN C; DEACETOXYCEPHALOSPORIN C SYNTHETASE; PENICILLIN G; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; KINETICS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 0035906733     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4649     Document Type: Article

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