-
1
-
-
0345282976
-
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins
-
N. Ahmed, P.J. Thornalley, J. Dawczynski, S. Franke, J. Strobel, G. Stein, and G.M. Haik Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins Invest. Ophthalmol Vis. Sci. 44 2003 5287 5292
-
(2003)
Invest. Ophthalmol Vis. Sci.
, vol.44
, pp. 5287-5292
-
-
Ahmed, N.1
Thornalley, P.J.2
Dawczynski, J.3
Franke, S.4
Strobel, J.5
Stein, G.6
Haik, G.M.7
-
2
-
-
0034770810
-
Structural evidence of human nuclear fiber compaction as a function of ageing and cataractogenesis
-
K.J. Al-Ghoul, R.K. Nordgren, A.J. Kuszak, C.D. Freel, M.J. Costello, and J.R. Kuszak Structural evidence of human nuclear fiber compaction as a function of ageing and cataractogenesis Exp. Eye Res. 2001 199 214
-
(2001)
Exp. Eye Res.
, pp. 199-214
-
-
Al-Ghoul, K.J.1
Nordgren, R.K.2
Kuszak, A.J.3
Freel, C.D.4
Costello, M.J.5
Kuszak, J.R.6
-
4
-
-
18044375675
-
-
International Congress of Eye Research Sydney
-
R.R. Ansari, K.I. Suh, M.B. Datiles, F.J. Giblin, J.I. Clark, and J. Kaplan Dynamic Light Scattering Evaluation of Oxidative Stress and Protection in the Lens 2004 International Congress of Eye Research Sydney
-
(2004)
Dynamic Light Scattering Evaluation of Oxidative Stress and Protection in the Lens
-
-
Ansari, R.R.1
Suh, K.I.2
Datiles, M.B.3
Giblin, F.J.4
Clark, J.I.5
Kaplan, J.6
-
5
-
-
0031149920
-
Oxidation products of 3-hydroxykynurenine bind to lens proteins: Relevance for nuclear cataract
-
J.A. Aquilina, J.A. Carver, and R.J. Truscott Oxidation products of 3-hydroxykynurenine bind to lens proteins: relevance for nuclear cataract Exp. Eye Res. 64 1997 727 735
-
(1997)
Exp. Eye Res.
, vol.64
, pp. 727-735
-
-
Aquilina, J.A.1
Carver, J.A.2
Truscott, R.J.3
-
6
-
-
0034719122
-
Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine
-
J.A. Aquilina, J.A. Carver, and R.J. Truscott Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine Biochemistry 39 2000 16176 16184
-
(2000)
Biochemistry
, vol.39
, pp. 16176-16184
-
-
Aquilina, J.A.1
Carver, J.A.2
Truscott, R.J.3
-
7
-
-
0036043809
-
Risk factors for nuclear lens opacification: The Reykjavik Eye Study
-
A. Arnarsson, F. Jonasson, H. Sasaki, M. Ono, V. Jonsson, M. Kojima, N. Katoh, K. Sasaki, and G. Reykjavik Eye Study Risk factors for nuclear lens opacification: the Reykjavik Eye Study Dev. Ophthalmol. 35 2002 12 20
-
(2002)
Dev. Ophthalmol.
, vol.35
, pp. 12-20
-
-
Arnarsson, A.1
Jonasson, F.2
Sasaki, H.3
Ono, M.4
Jonsson, V.5
Kojima, M.6
Katoh, N.7
Sasaki, K.8
Reykjavik Eye Study, G.9
-
8
-
-
0142231929
-
Water permeability of C-terminally truncated aquaporin 0 (AQP0 1-243) observed in the aging human lens
-
L.E. Ball, M. Little, M.W. Nowak, D.L. Garland, R.K. Crouch, and K.L. Schey Water permeability of C-terminally truncated aquaporin 0 (AQP0 1-243) observed in the aging human lens Invest. Ophthalmol. Vis. Sci. 44 2003 4820 4828
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 4820-4828
-
-
Ball, L.E.1
Little, M.2
Nowak, M.W.3
Garland, D.L.4
Crouch, R.K.5
Schey, K.L.6
-
9
-
-
0017211777
-
Changes in blue fluorescence intensity and colouration of human lens protein with normal lens aging and nuclear cataract
-
M. Bando, Y. Ishii, and A. Nakajima Changes in blue fluorescence intensity and colouration of human lens protein with normal lens aging and nuclear cataract Ophthalmic Res. 8 1976 456 463
-
(1976)
Ophthalmic Res.
, vol.8
, pp. 456-463
-
-
Bando, M.1
Ishii, Y.2
Nakajima, A.3
-
10
-
-
1642527347
-
Oxygen tension in the rabbit lens and vitreous before and after vitrectomy
-
I.A. Barbazetto, J. Liang, S.H. Chang, L. Zheng, A. Spector, and J.P. Dillon Oxygen tension in the rabbit lens and vitreous before and after vitrectomy Exp. Eye Res. 78 2004 917 924
-
(2004)
Exp. Eye Res.
, vol.78
, pp. 917-924
-
-
Barbazetto, I.A.1
Liang, J.2
Chang, S.H.3
Zheng, L.4
Spector, A.5
Dillon, J.P.6
-
11
-
-
0014341351
-
Free amino acids in senile cataractous lenses: Possible osmotic etiology
-
G.W. Barber Free amino acids in senile cataractous lenses: possible osmotic etiology Invest. Ophthalmol. 7 1968 564 583
-
(1968)
Invest. Ophthalmol.
, vol.7
, pp. 564-583
-
-
Barber, G.W.1
-
12
-
-
0015849709
-
Human cataractogenesis: A review
-
G.W. Barber Human cataractogenesis: a review Exp. Eye Res. 16 1973 85 94
-
(1973)
Exp. Eye Res.
, vol.16
, pp. 85-94
-
-
Barber, G.W.1
-
13
-
-
0035800832
-
Defining a link between gap junction communication, proteolysis, and cataract formation
-
A. Baruch, D. Greenbaum, E.T. Levy, P.A. Nielsen, N.B. Gilula, N.M. Kumar, and M. Bogyo Defining a link between gap junction communication, proteolysis, and cataract formation J. Biol. Chem. 276 2001 28999 29006
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28999-29006
-
-
Baruch, A.1
Greenbaum, D.2
Levy, E.T.3
Nielsen, P.A.4
Gilula, N.B.5
Kumar, N.M.6
Bogyo, M.7
-
14
-
-
0034893715
-
The role of AGEs in aging: Causation or correlation
-
J.W. Baynes The role of AGEs in aging: causation or correlation Exp. Gerontol. 36 2001 1527 1537
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1527-1537
-
-
Baynes, J.W.1
-
15
-
-
0034781728
-
The presence of a human UV filter within the lens represents an oxidative stress
-
Y. Berry, and R.J. Truscott The presence of a human UV filter within the lens represents an oxidative stress Exp. Eye Res. 72 2001 411 421
-
(2001)
Exp. Eye Res.
, vol.72
, pp. 411-421
-
-
Berry, Y.1
Truscott, R.J.2
-
16
-
-
0033831707
-
Impact of aging and hyperbaric oxygen in vivo on guinea pig lens lipids and nuclear light scatter
-
D. Borchman, F.J. Giblin, V.R. Leverenz, V.N. Reddy, L.R. Lin, M.C. Yappert, D. Tang, and L. Li Impact of aging and hyperbaric oxygen in vivo on guinea pig lens lipids and nuclear light scatter Invest. Ophthalmol. Vis. Sci. 41 2000 3061 3073
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 3061-3073
-
-
Borchman, D.1
Giblin, F.J.2
Leverenz, V.R.3
Reddy, V.N.4
Lin, L.R.5
Yappert, M.C.6
Tang, D.7
Li, L.8
-
17
-
-
0032726186
-
UV filter compounds in human lenses: The origin of 4-(2-amino-3- hydroxyphenyl)-4-oxobutanoic acid O-beta-d-glucoside
-
L.M. Bova, A.M. Wood, J.F. Jamie, and R.J. Truscott UV filter compounds in human lenses: the origin of 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-beta-d-glucoside Invest. Ophthalmol. Vis. Sci. 40 1999 3237 3244
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, pp. 3237-3244
-
-
Bova, L.M.1
Wood, A.M.2
Jamie, J.F.3
Truscott, R.J.4
-
20
-
-
0033981119
-
The ageing lens
-
A.J. Bron, G.F. Vrensen, J. Koretz, G. Maraini, and J.J. Harding The ageing lens Ophthalmologica 214 2000 86 104
-
(2000)
Ophthalmologica
, vol.214
, pp. 86-104
-
-
Bron, A.J.1
Vrensen, G.F.2
Koretz, J.3
Maraini, G.4
Harding, J.J.5
-
21
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases.[see comment]
-
M. Bucciantini, E. Giannoni, F. Chiti, F. Baroni, L. Formigli, J. Zurdo, N. Taddei, G. Ramponi, and C.M. Dobson Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases.[see comment] Nature 416 2002 507 511
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
-
22
-
-
0015400514
-
The behaviour of reduced proteins from normal and cataractous lenses in highly dissociating media: A cross-linked protein in cataractous lenses
-
R.H. Buckingham The behaviour of reduced proteins from normal and cataractous lenses in highly dissociating media: a cross-linked protein in cataractous lenses Exp. Eye Res. 14 1972 123 129
-
(1972)
Exp. Eye Res.
, vol.14
, pp. 123-129
-
-
Buckingham, R.H.1
-
23
-
-
8544225701
-
Liquid chromatography/mass-spectrometric characterization of sphingomyelin and dihydrosphingomyelin of human lens membranes
-
W.C. Byrdwell, and D. Borchman Liquid chromatography/mass-spectrometric characterization of sphingomyelin and dihydrosphingomyelin of human lens membranes Ophthalmic Res. 29 1997 191 206
-
(1997)
Ophthalmic Res.
, vol.29
, pp. 191-206
-
-
Byrdwell, W.C.1
Borchman, D.2
-
24
-
-
0022469901
-
Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice
-
H.I. Calvin, C. Medvedovsky, and B.V. Worgul Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice Science 233 1986 553 555
-
(1986)
Science
, vol.233
, pp. 553-555
-
-
Calvin, H.I.1
Medvedovsky, C.2
Worgul, B.V.3
-
26
-
-
0031464278
-
Molecular evidence for the involvement of alpha crystallin in the colouration/crosslinking of crystallins in age-related nuclear cataract
-
Y.C. Chen, G.E. Reid, R.J. Simpson, and R.J. Truscott Molecular evidence for the involvement of alpha crystallin in the colouration/crosslinking of crystallins in age-related nuclear cataract Exp. Eye Res. 65 1997 835 840
-
(1997)
Exp. Eye Res.
, vol.65
, pp. 835-840
-
-
Chen, Y.C.1
Reid, G.E.2
Simpson, R.J.3
Truscott, R.J.4
-
27
-
-
0035958673
-
Similarity of the yellow chromophores isolated from human cataracts with those from ascorbic acid-modified calf lens proteins: Evidence for ascorbic acid glycation during cataract formation
-
R. Cheng, B. Lin, K.W. Lee, and B.J. Ortwerth Similarity of the yellow chromophores isolated from human cataracts with those from ascorbic acid-modified calf lens proteins: evidence for ascorbic acid glycation during cataract formation Biochim. Biophys. Acta 1537 2001 14 26
-
(2001)
Biochim. Biophys. Acta
, vol.1537
, pp. 14-26
-
-
Cheng, R.1
Lin, B.2
Lee, K.W.3
Ortwerth, B.J.4
-
29
-
-
0021664289
-
Epidemiological and other studies in the assessment of factors contributing to cataractogenesis
-
R.M. Clayton, J. Cuthbert, J. Seth, C.I. Phillips, R.S. Bartholomew, and J.M. Reid Epidemiological and other studies in the assessment of factors contributing to cataractogenesis Ciba Found. Symp. 106 1984 25 47
-
(1984)
Ciba Found. Symp.
, vol.106
, pp. 25-47
-
-
Clayton, R.M.1
Cuthbert, J.2
Seth, J.3
Phillips, C.I.4
Bartholomew, R.S.5
Reid, J.M.6
-
30
-
-
0037080002
-
Alpha-crystallin chaperone-like activity and membrane binding in age-related cataracts
-
B.A. Cobb, and J.M. Petrash Alpha-crystallin chaperone-like activity and membrane binding in age-related cataracts Biochemistry 41 2002 483 490
-
(2002)
Biochemistry
, vol.41
, pp. 483-490
-
-
Cobb, B.A.1
Petrash, J.M.2
-
31
-
-
0017658442
-
Changes in the distribution of proteins in the aging human lens
-
S.D. Coghlan, and R.C. Augusteyn Changes in the distribution of proteins in the aging human lens Exp. Eye Res. 25 1977 603 611
-
(1977)
Exp. Eye Res.
, vol.25
, pp. 603-611
-
-
Coghlan, S.D.1
Augusteyn, R.C.2
-
32
-
-
3142653071
-
Nuclear cataract shows significant familial aggregation in an older population after adjustment for possible shared environmental factors
-
N. Congdon, K.W. Broman, H. Lai, B. Munoz, H. Bowie, D. Gilber, R. Wojciechowski, C. Alston, and S.K. West Nuclear cataract shows significant familial aggregation in an older population after adjustment for possible shared environmental factors Invest. Ophthalmol. Vis. Sci. 45 2004 2182 2186
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 2182-2186
-
-
Congdon, N.1
Broman, K.W.2
Lai, H.3
Munoz, B.4
Bowie, H.5
Gilber, D.6
Wojciechowski, R.7
Alston, C.8
West, S.K.9
-
33
-
-
0027930117
-
Micromolar levels of intracellular calcium reduce gap junctional permeability in lens cultures
-
J.M. Crow, M.M. Atkinson, and R.G. Johnson Micromolar levels of intracellular calcium reduce gap junctional permeability in lens cultures Invest. Ophthalmol. Vis. Sci. 35 1994 3332 3341
-
(1994)
Invest. Ophthalmol. Vis. Sci.
, vol.35
, pp. 3332-3341
-
-
Crow, J.M.1
Atkinson, M.M.2
Johnson, R.G.3
-
35
-
-
0027468977
-
Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation
-
L.L. David, T.R. Shearer, and M. Shih Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation J. Biol. Chem. 268 1993 1937 1940
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1937-1940
-
-
David, L.L.1
Shearer, T.R.2
Shih, M.3
-
36
-
-
0031216445
-
Free cysteine levels in normal human lenses
-
J.E. Dickerson Jr, and M.F. Lou Free cysteine levels in normal human lenses Exp. Eye Res. 65 1997 451 454
-
(1997)
Exp. Eye Res.
, vol.65
, pp. 451-454
-
-
Dickerson Jr., J.E.1
Lou, M.F.2
-
37
-
-
0024388858
-
Active transport of ascorbic acid into lens epithelium of the rat
-
J. DiMattio Active transport of ascorbic acid into lens epithelium of the rat Exp. Eye Res. 49 1989 873 885
-
(1989)
Exp. Eye Res.
, vol.49
, pp. 873-885
-
-
Dimattio, J.1
-
38
-
-
0024414295
-
Human lens membrane cation permeability increases with age
-
G. Duncan, K.R. Hightower, S.A. Gandolfi, J. Tomlinson, and G. Maraini Human lens membrane cation permeability increases with age Invest. Ophthalmol. Vis. Sci. 30 1989 1855 1859
-
(1989)
Invest. Ophthalmol. Vis. Sci.
, vol.30
, pp. 1855-1859
-
-
Duncan, G.1
Hightower, K.R.2
Gandolfi, S.A.3
Tomlinson, J.4
Maraini, G.5
-
40
-
-
0031856521
-
Age-related nuclear lens opacities are associated with reduced growth before 1 year of age. [see comments]
-
J.R. Evans, A. Rauf, A. Aihie Sayer, R.P. Wormald, and C. Cooper Age-related nuclear lens opacities are associated with reduced growth before 1 year of age. [see comments] Invest. Ophthalmol. Vis. Sci. 39 1998 1740 1744
-
(1998)
Invest. Ophthalmol. Vis. Sci.
, vol.39
, pp. 1740-1744
-
-
Evans, J.R.1
Rauf, A.2
Aihie Sayer, A.3
Wormald, R.P.4
Cooper, C.5
-
41
-
-
0029985732
-
Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid in mammalian lenses, and beta-amyloid has toxic effects on lens epithelial cells
-
P.H. Frederikse, D. Garland, J.S. Zigler Jr, and J. Piatigorsky Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid in mammalian lenses, and beta-amyloid has toxic effects on lens epithelial cells J. Biol. Chem. 271 1996 10169 10174
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10169-10174
-
-
Frederikse, P.H.1
Garland, D.2
Zigler Jr., J.S.3
Piatigorsky, J.4
-
42
-
-
0037375363
-
Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model
-
C.D. Freel, K.O. Gilliland, H.E. Mekeel, F.J. Giblin, and M.J. Costello Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model Exp. Eye Res. 76 2003 405 415
-
(2003)
Exp. Eye Res.
, vol.76
, pp. 405-415
-
-
Freel, C.D.1
Gilliland, K.O.2
Mekeel, H.E.3
Giblin, F.J.4
Costello, M.J.5
-
43
-
-
0032582822
-
The hydroxyl radical in lens nuclear cataractogenesis
-
S. Fu, R. Dean, M. Southan, and R. Truscott The hydroxyl radical in lens nuclear cataractogenesis J. Biol. Chem. 273 1998 28603 28609
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28603-28609
-
-
Fu, S.1
Dean, R.2
Southan, M.3
Truscott, R.4
-
44
-
-
0025365741
-
Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: A hypothesis
-
D. Garland Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: a hypothesis Exp. Eye Res. 50 1990 677 682
-
(1990)
Exp. Eye Res.
, vol.50
, pp. 677-682
-
-
Garland, D.1
-
45
-
-
0022860324
-
Structural changes in bovine lens crystallins induced by ascorbate, metal, and oxygen
-
D. Garland, S.J. Zigler, and J. Kinoshita Structural changes in bovine lens crystallins induced by ascorbate, metal, and oxygen Arch. Biochem. Biophys. 251 1986 771 776
-
(1986)
Arch. Biochem. Biophys.
, vol.251
, pp. 771-776
-
-
Garland, D.1
Zigler, S.J.2
Kinoshita, J.3
-
46
-
-
0008318301
-
Selective oxidation of cysteine and methionine in normal and senile cataractous lenses
-
M.H. Garner, and A. Spector Selective oxidation of cysteine and methionine in normal and senile cataractous lenses Proc. Natl Acad. Sci. USA 77 1980 1274 1277
-
(1980)
Proc. Natl Acad. Sci. USA
, vol.77
, pp. 1274-1277
-
-
Garner, M.H.1
Spector, A.2
-
47
-
-
62049086295
-
Redox availability of lens iron and copper: Implications for HO* generation in cataract
-
B. Garner, K. Roberg, M. Qian, U.T. Brunk, J.W. Eaton, and R.J. Truscott Redox availability of lens iron and copper: implications for HO* generation in cataract Redox Rep. 4 1999 313 315
-
(1999)
Redox Rep.
, vol.4
, pp. 313-315
-
-
Garner, B.1
Roberg, K.2
Qian, M.3
Brunk, U.T.4
Eaton, J.W.5
Truscott, R.J.6
-
48
-
-
0033977610
-
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
-
B. Garner, M.J. Davies, and R.J.W. Truscott Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract Exp. Eye Res. 70 2000 81 88
-
(2000)
Exp. Eye Res.
, vol.70
, pp. 81-88
-
-
Garner, B.1
Davies, M.J.2
Truscott, R.J.W.3
-
49
-
-
0034012636
-
Glutathione: A vital lens antioxidant
-
F.J. Giblin Glutathione: a vital lens antioxidant J. Ocul. Pharmacol. Ther. 16 2000 121 135
-
(2000)
J. Ocul. Pharmacol. Ther.
, vol.16
, pp. 121-135
-
-
Giblin, F.J.1
-
51
-
-
0031986381
-
Presbyopia and the optical changes in the human crystalline lens with age
-
A. Glasser, and M.C. Campbell Presbyopia and the optical changes in the human crystalline lens with age Vis. Res. 38 1998 209 229
-
(1998)
Vis. Res.
, vol.38
, pp. 209-229
-
-
Glasser, A.1
Campbell, M.C.2
-
52
-
-
0037433668
-
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease
-
L.E. Goldstein, J.A. Muffat, R.A. Cherny, R.D. Moir, M.H. Ericsson, X. Huang, C. Mavros, J.A. Coccia, and K.Y. Faget Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease Lancet 361 2003 1258 1265
-
(2003)
Lancet
, vol.361
, pp. 1258-1265
-
-
Goldstein, L.E.1
Muffat, J.A.2
Cherny, R.A.3
Moir, R.D.4
Ericsson, M.H.5
Huang, X.6
Mavros, C.7
Coccia, J.A.8
Faget, K.Y.9
-
53
-
-
33646859380
-
-
ARVO abstract #3963.
-
Grami, V., Marrero, Y.G., Tang, D., Yappert, M.C., Borchman, D., 2004. The influence of age and diabetes on the binding capacity of alpha crystallin to human lens lipids. ARVO abstract #3963.
-
(2004)
The Influence of Age and Diabetes on the Binding Capacity of Alpha Crystallin to Human Lens Lipids
-
-
Grami, V.1
Marrero, Y.G.2
Tang, D.3
Yappert, M.C.4
Borchman, D.5
-
54
-
-
0027416998
-
Age dependent deamidation of alpha b crystallin
-
P. Groenen, M. Vandongen, C. Voorter, H. Bloemendal, and W. Dejong Age dependent deamidation of alpha b crystallin FEBS Lett. 322 1993 69 72
-
(1993)
FEBS Lett.
, vol.322
, pp. 69-72
-
-
Groenen, P.1
Vandongen, M.2
Voorter, C.3
Bloemendal, H.4
Dejong, W.5
-
55
-
-
0026749942
-
Hydroxyl radical mediated damage to proteins, with special reference to the crystallins
-
P. Guptasarma, D. Balasubramanian, S. Matsugo, and I. Saito Hydroxyl radical mediated damage to proteins, with special reference to the crystallins Biochemistry 31 1992 4296 4303
-
(1992)
Biochemistry
, vol.31
, pp. 4296-4303
-
-
Guptasarma, P.1
Balasubramanian, D.2
Matsugo, S.3
Saito, I.4
-
57
-
-
0033829222
-
The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage
-
S.R. Hanson, A. Hasan, D.L. Smith, and J.B. Smith The major in vivo modifications of the human water-insoluble lens crystallins are disulfide bonds, deamidation, methionine oxidation and backbone cleavage Exp. Eye Res. 71 2000 195 207
-
(2000)
Exp. Eye Res.
, vol.71
, pp. 195-207
-
-
Hanson, S.R.1
Hasan, A.2
Smith, D.L.3
Smith, J.B.4
-
59
-
-
0346727569
-
Importance of vitreous liquefaction in age-related cataract
-
G.J. Harocopos, Y.B. Shui, M. McKinnon, N.M. Holekamp, M.O. Gordon, and D.C. Beebe Importance of vitreous liquefaction in age-related cataract Invest. Ophthalmol. Vis. Sci. 45 2004 77 85
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 77-85
-
-
Harocopos, G.J.1
Shui, Y.B.2
McKinnon, M.3
Holekamp, N.M.4
Gordon, M.O.5
Beebe, D.C.6
-
60
-
-
2942532502
-
Molecular genetics of age-related cataract
-
Hejtmancik, J.F., Kantorow, M., 2004. Molecular genetics of age-related cataract. Exp. Eye Res. 79, 3-9.
-
(2004)
Exp. Eye Res.
, vol.79
, pp. 3-9
-
-
Hejtmancik, J.F.1
Kantorow, M.2
-
61
-
-
18044365894
-
Massive increase in the stiffness of the human lens nucleus with age: The basis for presbyopia?
-
Heys, K.R., Cram, S.L., Truscott, R.J.W., 2004. Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia? Mol. Vis. 10, 956-963.
-
(2004)
Mol. Vis.
, vol.10
, pp. 956-963
-
-
Heys, K.R.1
Cram, S.L.2
Truscott, R.J.W.3
-
62
-
-
0029071850
-
Transglutaminase activity in normal human lenses and in senile cataracts
-
V. Hidasi, and L. Muszbek Transglutaminase activity in normal human lenses and in senile cataracts Ann. Clin. Lab. Sci. 25 1995 236 240
-
(1995)
Ann. Clin. Lab. Sci.
, vol.25
, pp. 236-240
-
-
Hidasi, V.1
Muszbek, L.2
-
63
-
-
0028330335
-
The effects of age on glutathione peroxidase and glutathione reductase activities in lenses of Old World simians and prosimians
-
A.M. Holleschau, and W.B. Rathbun The effects of age on glutathione peroxidase and glutathione reductase activities in lenses of Old World simians and prosimians Curr. Eye Res. 13 1994 331 336
-
(1994)
Curr. Eye Res.
, vol.13
, pp. 331-336
-
-
Holleschau, A.M.1
Rathbun, W.B.2
-
64
-
-
0032731157
-
Human lens colouration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxykynurenine glucoside
-
B. Hood, B. Garner, and R.J.W. Truscott Human lens colouration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxykynurenine glucoside J. Biol. Chem. 274 1999 32547 32550
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32547-32550
-
-
Hood, B.1
Garner, B.2
Truscott, R.J.W.3
-
65
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
J. Horwitz Alpha-crystallin can function as a molecular chaperone Proc. Natl Acad. Sci. USA 89 1992 10449 10453
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
66
-
-
0037047118
-
The protofilament structure of insulin amyloid fibrils
-
J.L. Jimenez, E.J. Nettleton, M. Bouchard, C.V. Robinson, C.M. Dobson, and H.R. Saibil The protofilament structure of insulin amyloid fibrils Proc. Natl Acad. Sci. USA 99 2002 9196 9201
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 9196-9201
-
-
Jimenez, J.L.1
Nettleton, E.J.2
Bouchard, M.3
Robinson, C.V.4
Dobson, C.M.5
Saibil, H.R.6
-
67
-
-
0023176263
-
Detection of the crosslinking amino acid histidinoalanine in human brown cataractous protein
-
T. Kanayama, Y. Miyanaga, K. Horiuchi, and D. Fujimoto Detection of the crosslinking amino acid histidinoalanine in human brown cataractous protein Exp. Eye Res. 44 1987 165 169
-
(1987)
Exp. Eye Res.
, vol.44
, pp. 165-169
-
-
Kanayama, T.1
Miyanaga, Y.2
Horiuchi, K.3
Fujimoto, D.4
-
68
-
-
0023232998
-
Protein processing in lens intercellular junctions: Cleavage of MP70 to MP38
-
J. Kistler, and S. Bullivant Protein processing in lens intercellular junctions: cleavage of MP70 to MP38 Invest. Ophthalmol. Vis. Sci. 28 1987 1687 1692
-
(1987)
Invest. Ophthalmol. Vis. Sci.
, vol.28
, pp. 1687-1692
-
-
Kistler, J.1
Bullivant, S.2
-
69
-
-
0029082459
-
Ocular lens gap junctions: Protein expression, assembly, and structure-function analysis
-
J. Kistler, C. Evans, P. Donaldson, S. Bullivant, J. Bond, S. Eastwood, M. Roos, Y. Dong, and T. Gruijters Ocular lens gap junctions: protein expression, assembly, and structure-function analysis Microsc. Res. Tech. 31 1995 347 356
-
(1995)
Microsc. Res. Tech.
, vol.31
, pp. 347-356
-
-
Kistler, J.1
Evans, C.2
Donaldson, P.3
Bullivant, S.4
Bond, J.5
Eastwood, S.6
Roos, M.7
Dong, Y.8
Gruijters, T.9
-
70
-
-
0023871074
-
Characterization of disulfide-linked crystallins associated with human cataractous lens membranes
-
T. Kodama, and L. Takemoto Characterization of disulfide-linked crystallins associated with human cataractous lens membranes Invest. Ophthalmol. Vis. Sci. 29 1988 145 149
-
(1988)
Invest. Ophthalmol. Vis. Sci.
, vol.29
, pp. 145-149
-
-
Kodama, T.1
Takemoto, L.2
-
71
-
-
0020585294
-
The Emory mouse cataract: Loss of soluble protein, glutathione, protein sulfhydryl and other changes
-
J.F. Kuck, and K.D. Kuck The Emory mouse cataract: loss of soluble protein, glutathione, protein sulfhydryl and other changes Exp. Eye Res. 36 1983 351 362
-
(1983)
Exp. Eye Res.
, vol.36
, pp. 351-362
-
-
Kuck, J.F.1
Kuck, K.D.2
-
72
-
-
0020043380
-
Total sulfhydryl by Raman spectroscopy in the intact lens of several species: Variations in the nucleus and along the optical axis during aging
-
J.F. Kuck, N.T. Yu, and C.C. Askren Total sulfhydryl by Raman spectroscopy in the intact lens of several species: variations in the nucleus and along the optical axis during aging Exp. Eye Res. 34 1982 23 37 (issn: 0014-4835)
-
(1982)
Exp. Eye Res.
, vol.34
, pp. 23-37
-
-
Kuck, J.F.1
Yu, N.T.2
Askren, C.C.3
-
73
-
-
0032128377
-
Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry
-
K.J. Lampi, Z. Ma, S.R. Hanson, M. Azuma, M. Shih, T.R. Shearer, D.L. Smith, J.B. Smith, and L.L. David Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry Exp. Eye Res. 67 1998 31 43
-
(1998)
Exp. Eye Res.
, vol.67
, pp. 31-43
-
-
Lampi, K.J.1
Ma, Z.2
Hanson, S.R.3
Azuma, M.4
Shih, M.5
Shearer, T.R.6
Smith, D.L.7
Smith, J.B.8
David, L.L.9
-
74
-
-
0034780550
-
Deamidation of human B1 alters the elongated structure of the dimer
-
K.J. Lampi, J.T. Oxford, H.P. Bachinger, T.R. Shearer, L.L. David, and D.M. Kapfer Deamidation of human B1 alters the elongated structure of the dimer Exp. Eye Res. 72 2001 279 288
-
(2001)
Exp. Eye Res.
, vol.72
, pp. 279-288
-
-
Lampi, K.J.1
Oxford, J.T.2
Bachinger, H.P.3
Shearer, T.R.4
David, L.L.5
Kapfer, D.M.6
-
75
-
-
0035008831
-
In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92
-
V.N. Lapko, D.L. Smith, and J.B. Smith In vivo carbamylation and acetylation of water-soluble human lens alphaB-crystallin lysine 92 Protein Sci. 10 2001 1130 1136
-
(2001)
Protein Sci.
, vol.10
, pp. 1130-1136
-
-
Lapko, V.N.1
Smith, D.L.2
Smith, J.B.3
-
76
-
-
0037047002
-
Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure
-
V.N. Lapko, A.G. Purkiss, D.L. Smith, and J.B. Smith Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure Biochemistry 41 2002 8638 8648
-
(2002)
Biochemistry
, vol.41
, pp. 8638-8648
-
-
Lapko, V.N.1
Purkiss, A.G.2
Smith, D.L.3
Smith, J.B.4
-
77
-
-
0037126714
-
S-methylated cysteines in human lens gamma S-crystallins
-
V.N. Lapko, D.L. Smith, and J.B. Smith S-methylated cysteines in human lens gamma S-crystallins Biochemistry 41 2002 14645 14651
-
(2002)
Biochemistry
, vol.41
, pp. 14645-14651
-
-
Lapko, V.N.1
Smith, D.L.2
Smith, J.B.3
-
78
-
-
0032128061
-
The relative ability of glucose and ascorbate to glycate and crosslink lens proteins in vitro. off
-
K.W. Lee, V. Mossine, and B.J. Ortwerth The relative ability of glucose and ascorbate to glycate and crosslink lens proteins in vitro. off Exp. Eye Res. 67 1998 95 104
-
(1998)
Exp. Eye Res.
, vol.67
, pp. 95-104
-
-
Lee, K.W.1
Mossine, V.2
Ortwerth, B.J.3
-
79
-
-
0025913106
-
NMR and fluorescence studies on human and animal lenses
-
S. Lerman NMR and fluorescence studies on human and animal lenses Lens Eye Toxicol. Res. 8 1991 121 154
-
(1991)
Lens Eye Toxicol. Res.
, vol.8
, pp. 121-154
-
-
Lerman, S.1
-
80
-
-
0030958516
-
Processing of the gap junction protein connexin50 in the ocular lens is accomplished by calpain
-
J.S. Lin, S. Fitzgerald, Y. Dong, C. Knight, P. Donaldson, and J. Kistler Processing of the gap junction protein connexin50 in the ocular lens is accomplished by calpain Eur. J. Cell Biol. 73 1997 141 149
-
(1997)
Eur. J. Cell Biol.
, vol.73
, pp. 141-149
-
-
Lin, J.S.1
Fitzgerald, S.2
Dong, Y.3
Knight, C.4
Donaldson, P.5
Kistler, J.6
-
81
-
-
0031664396
-
Spatial differences in gap junction gating in the lens are a consequence of connexin cleavage
-
J.S. Lin, R. Eckert, J. Kistler, and P. Donaldson Spatial differences in gap junction gating in the lens are a consequence of connexin cleavage Eur. J. Cell Biol. 76 1998 246 250
-
(1998)
Eur. J. Cell Biol.
, vol.76
, pp. 246-250
-
-
Lin, J.S.1
Eckert, R.2
Kistler, J.3
Donaldson, P.4
-
82
-
-
0031745913
-
In vivo acetylation identified at lysine 70 of human lens alphaA- crystallin
-
P.P. Lin, R.C. Barry, D.L. Smith, and J.B. Smith In vivo acetylation identified at lysine 70 of human lens alphaA- crystallin Protein Sci. 7 1998 1451 1457
-
(1998)
Protein Sci.
, vol.7
, pp. 1451-1457
-
-
Lin, P.P.1
Barry, R.C.2
Smith, D.L.3
Smith, J.B.4
-
83
-
-
0035865589
-
The molecular chaperone alpha-crystallin is in kinetic competition with aggregation to stabilize a monomeric molten-globule form of alpha-lactalbumin
-
R.A. Lindner, T.M. Treweek, and J.A. Carver The molecular chaperone alpha-crystallin is in kinetic competition with aggregation to stabilize a monomeric molten-globule form of alpha-lactalbumin Biochem. J. 354 2001 79 87
-
(2001)
Biochem. J.
, vol.354
, pp. 79-87
-
-
Lindner, R.A.1
Treweek, T.M.2
Carver, J.A.3
-
84
-
-
0029328485
-
The generation of hydrogen peroxide by the UV-A irradiation of human lens proteins
-
M. Linetsky, and B.J. Ortwerth The generation of hydrogen peroxide by the UV-A irradiation of human lens proteins Photochem. Photobiol. 62 1995 87 93
-
(1995)
Photochem. Photobiol.
, vol.62
, pp. 87-93
-
-
Linetsky, M.1
Ortwerth, B.J.2
-
85
-
-
0030198290
-
The generation of superoxide anion by the UVA irradiation of human lens proteins
-
M. Linetsky, H.L. James, and B.J. Ortwerth The generation of superoxide anion by the UVA irradiation of human lens proteins Exp. Eye Res. 63 1996 67 74
-
(1996)
Exp. Eye Res.
, vol.63
, pp. 67-74
-
-
Linetsky, M.1
James, H.L.2
Ortwerth, B.J.3
-
87
-
-
0037133283
-
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-l-carnitine and/or R-alpha -lipoic acid [erratum appears in Proceedings of the National Academy of Sciences of the United States of America 2002 May 14;99(10):7184-7185]
-
J. Liu, E. Head, A.M. Gharib, W. Yuan, R.T. Ingersoll, T.M. Hagen, C.W. Cotman, and B.N. Ames Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-l-carnitine and/or R-alpha -lipoic acid [erratum appears in Proceedings of the National Academy of Sciences of the United States of America 2002 May 14;99(10):7184-7185] Proc. Natl Acad. Sci. USA 99 2002 2356 2361
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2356-2361
-
-
Liu, J.1
Head, E.2
Gharib, A.M.3
Yuan, W.4
Ingersoll, R.T.5
Hagen, T.M.6
Cotman, C.W.7
Ames, B.N.8
-
88
-
-
0034092928
-
Thiol regulation in the lens
-
M.F. Lou Thiol regulation in the lens J. Ocul. Pharmacol. Ther. 16 2000 137 148
-
(2000)
J. Ocul. Pharmacol. Ther.
, vol.16
, pp. 137-148
-
-
Lou, M.F.1
-
89
-
-
0033057535
-
Correlation of nuclear color and opalescence with protein S-thiolation in human lenses
-
M.F. Lou, J.E. Dickerson Jr, W.H. Tung, J.K. Wolfe, and L.T. Chylack Jr Correlation of nuclear color and opalescence with protein S-thiolation in human lenses Exp. Eye Res. 68 1999 547 552
-
(1999)
Exp. Eye Res.
, vol.68
, pp. 547-552
-
-
Lou, M.F.1
Dickerson Jr., J.E.2
Tung, W.H.3
Wolfe, J.K.4
Chylack Jr., L.T.5
-
90
-
-
18444391517
-
Shotgun identification of protein modifications from protein complexes and lens tissue
-
M.J. MacCoss, W.H. McDonald, A. Saraf, R. Sadygov, J.M. Clark, J.J. Tasto, K.L. Gould, D. Wolters, and M. Washburn Shotgun identification of protein modifications from protein complexes and lens tissue Proc. Natl Acad. Sci. USA 99 2002 7900 7905
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 7900-7905
-
-
MacCoss, M.J.1
McDonald, W.H.2
Saraf, A.3
Sadygov, R.4
Clark, J.M.5
Tasto, J.J.6
Gould, K.L.7
Wolters, D.8
Washburn, M.9
-
91
-
-
0023448025
-
Amino acid transport and protein synthesis in human normal and cataractous lenses
-
J. Marcantonio, and G. Duncan Amino acid transport and protein synthesis in human normal and cataractous lenses Curr. Eye Res. 6 1987 1299 1308
-
(1987)
Curr. Eye Res.
, vol.6
, pp. 1299-1308
-
-
Marcantonio, J.1
Duncan, G.2
-
92
-
-
0017375375
-
Aspartic acid racemisation in the human lens during ageing and in cataract formation
-
P.M. Masters, J.L. Bada, and J.J. Zigler Aspartic acid racemisation in the human lens during ageing and in cataract formation Nature 268 1977 71 73
-
(1977)
Nature
, vol.268
, pp. 71-73
-
-
Masters, P.M.1
Bada, J.L.2
Zigler, J.J.3
-
93
-
-
0022336641
-
Spatial and temporal mapping of the age-related changes in human lens crystallins
-
M.J. McFall-Ngai, L.L. Ding, L.J. Takemoto, and J. Horwitz Spatial and temporal mapping of the age-related changes in human lens crystallins Exp. Eye Res. 41 1985 745 758
-
(1985)
Exp. Eye Res.
, vol.41
, pp. 745-758
-
-
McFall-Ngai, M.J.1
Ding, L.L.2
Takemoto, L.J.3
Horwitz, J.4
-
94
-
-
4644350442
-
Regulation of tissue oxygen levels in the mammalian lens
-
R. McNulty, H. Wang, R. Mathias, B.J. Ortwerth, R.J.W. Truscott, and S. Bassnett Regulation of tissue oxygen levels in the mammalian lens J. Physiol. 559 2004 883 898
-
(2004)
J. Physiol.
, vol.559
, pp. 883-898
-
-
McNulty, R.1
Wang, H.2
Mathias, R.3
Ortwerth, B.J.4
Truscott, R.J.W.5
Bassnett, S.6
-
95
-
-
0942276377
-
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation
-
S. Meehan, Y. Berry, B. Luisi, C.M. Dobson, J.A. Carver, and C.E. MacPhee Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation J. Biol. Chem. 279 2004 3413 3419
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3413-3419
-
-
Meehan, S.1
Berry, Y.2
Luisi, B.3
Dobson, C.M.4
Carver, J.A.5
MacPhee, C.E.6
-
96
-
-
0021741787
-
Vitrectomy for Macular Pucker
-
R.G. Michels Vitrectomy for Macular Pucker Ophthalmology 91 1984 1384 1388
-
(1984)
Ophthalmology
, vol.91
, pp. 1384-1388
-
-
Michels, R.G.1
-
97
-
-
0033374521
-
Age-related changes in the kinetics of water transport in normal human lenses
-
B.A. Moffat, K.A. Landman, R.J. Truscott, M.H. Sweeney, and J.M. Pope Age-related changes in the kinetics of water transport in normal human lenses Exp. Eye Res. 69 1999 663 669
-
(1999)
Exp. Eye Res.
, vol.69
, pp. 663-669
-
-
Moffat, B.A.1
Landman, K.A.2
Truscott, R.J.3
Sweeney, M.H.4
Pope, J.M.5
-
99
-
-
18044396831
-
Modifications of lens proteins by the oxidation products of ascorbate: Isolation and characterization of a marker for the maillard reaction by L-threose
-
R.H. Nagaraj, and V.M. Monnier Modifications of lens proteins by the oxidation products of ascorbate: isolation and characterization of a marker for the maillard reaction by L-threose Invest. Ophthalmol. Vis. Sci. 35 1994 1930
-
(1994)
Invest. Ophthalmol. Vis. Sci.
, vol.35
, pp. 1930
-
-
Nagaraj, R.H.1
Monnier, V.M.2
-
100
-
-
0023700292
-
Glutathione inhibits the glycation and crosslinking of lens proteins by ascorbic acid
-
B.J. Ortwerth, and P.R. Olesen Glutathione inhibits the glycation and crosslinking of lens proteins by ascorbic acid Exp. Eye Res. 47 1988 737 750
-
(1988)
Exp. Eye Res.
, vol.47
, pp. 737-750
-
-
Ortwerth, B.J.1
Olesen, P.R.2
-
101
-
-
0031758965
-
Singlet oxygen production correlates with His and Trp destruction in brunescent cataract water-insoluble proteins
-
B.J. Ortwerth, T.A. Casserly, and P.R. Olesen Singlet oxygen production correlates with His and Trp destruction in brunescent cataract water-insoluble proteins Exp. Eye Res. 67 1998 377 380
-
(1998)
Exp. Eye Res.
, vol.67
, pp. 377-380
-
-
Ortwerth, B.J.1
Casserly, T.A.2
Olesen, P.R.3
-
102
-
-
0024314190
-
Disulfide cross-linking of urea-insoluble proteins in rabbit lenses treated with hyperbaric oxygen
-
V. Padgaonkar, F.J. Giblin, and V.N. Reddy Disulfide cross-linking of urea-insoluble proteins in rabbit lenses treated with hyperbaric oxygen Exp. Eye Res. 49 1989 887 899
-
(1989)
Exp. Eye Res.
, vol.49
, pp. 887-899
-
-
Padgaonkar, V.1
Giblin, F.J.2
Reddy, V.N.3
-
103
-
-
0021675467
-
Nuclear cataract and myopia during hyperbaric oxygen therapy
-
B.M. Palmquist, B. Philipson, and P.O. Barr Nuclear cataract and myopia during hyperbaric oxygen therapy Br. J. Ophthalmol. 68 1984 113 117
-
(1984)
Br. J. Ophthalmol.
, vol.68
, pp. 113-117
-
-
Palmquist, B.M.1
Philipson, B.2
Barr, P.O.3
-
105
-
-
0025190906
-
Nonenzymatic glycosylation of protein does not increase with age in normal human lenses
-
J.S. Patrick, S.R. Thorpe, and J.W. Baynes Nonenzymatic glycosylation of protein does not increase with age in normal human lenses J. Gerontol. 45 1990 B18 B23
-
(1990)
J. Gerontol.
, vol.45
-
-
Patrick, J.S.1
Thorpe, S.R.2
Baynes, J.W.3
-
106
-
-
0032913131
-
Gating of cx46 gap junction hemichannels by calcium and voltage
-
A. Pfahnl, and G. Dahl Gating of cx46 gap junction hemichannels by calcium and voltage Pflugers Arch. - Eur. J. Physiol. 437 1999 345 353
-
(1999)
Pflugers Arch. - Eur. J. Physiol.
, vol.437
, pp. 345-353
-
-
Pfahnl, A.1
Dahl, G.2
-
107
-
-
0021698988
-
Crystallin genes: Templates for lens transparency
-
J. Piatigorsky, J.M. Nickerson, C.R. King, G. Inana, J.F. Hejtmancik, J.W. Hawkins, T. Borras, T. Shinohara, and G. Wistow Crystallin genes: templates for lens transparency Ciba Found. Symp. 106 1984 191 207
-
(1984)
Ciba Found. Symp.
, vol.106
, pp. 191-207
-
-
Piatigorsky, J.1
Nickerson, J.M.2
King, C.R.3
Inana, G.4
Hejtmancik, J.F.5
Hawkins, J.W.6
Borras, T.7
Shinohara, T.8
Wistow, G.9
-
108
-
-
0014373922
-
Color and solubility of the proteins of human cataracts
-
A. Pirie Color and solubility of the proteins of human cataracts Invest. Ophthalmol. 7 1968 634 650
-
(1968)
Invest. Ophthalmol.
, vol.7
, pp. 634-650
-
-
Pirie, A.1
-
109
-
-
0022648950
-
Activity of glutathione synthesis enzymes in the rhesus monkey lens related to age: A model for the human lens
-
W.B. Rathbun Activity of glutathione synthesis enzymes in the rhesus monkey lens related to age: a model for the human lens Curr. Eye Res. 5 1986 161 166
-
(1986)
Curr. Eye Res.
, vol.5
, pp. 161-166
-
-
Rathbun, W.B.1
-
110
-
-
0022885867
-
Activity of glutathione peroxidase and glutathione reductase in the human lens related to age
-
W.B. Rathbun, and M.G. Bovis Activity of glutathione peroxidase and glutathione reductase in the human lens related to age Curr. Eye Res. 5 1986 381 385
-
(1986)
Curr. Eye Res.
, vol.5
, pp. 381-385
-
-
Rathbun, W.B.1
Bovis, M.G.2
-
111
-
-
0022966309
-
Species survey of glutathione peroxidase and glutathione reductase: Search for an animal model of the human lens
-
W.B. Rathbun, M.G. Bovis, and A.M. Holleschau Species survey of glutathione peroxidase and glutathione reductase: search for an animal model of the human lens Ophthal. Res. 18 1986 282 287
-
(1986)
Ophthal. Res.
, vol.18
, pp. 282-287
-
-
Rathbun, W.B.1
Bovis, M.G.2
Holleschau, A.M.3
-
113
-
-
0021664931
-
Metabolism and function of glutathione in the lens
-
V.N. Reddy, and F.J. Giblin Metabolism and function of glutathione in the lens Ciba Found. Symp. 106 1984 65 87
-
(1984)
Ciba Found. Symp.
, vol.106
, pp. 65-87
-
-
Reddy, V.N.1
Giblin, F.J.2
-
115
-
-
0013358797
-
Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses
-
D. Roy, and A. Spector Absence of low-molecular-weight alpha crystallin in nuclear region of old human lenses Proc. Natl Acad. Sci. USA 73 1976 3484 3487
-
(1976)
Proc. Natl Acad. Sci. USA
, vol.73
, pp. 3484-3487
-
-
Roy, D.1
Spector, A.2
-
116
-
-
0029050241
-
Precipitation of crystallins from young rat lens by endogenous calpain
-
T.R. Shearer, M. Shih, M. Azuma, and L.L. David Precipitation of crystallins from young rat lens by endogenous calpain Exp. Eye Res. 61 1995 141 150
-
(1995)
Exp. Eye Res.
, vol.61
, pp. 141-150
-
-
Shearer, T.R.1
Shih, M.2
Azuma, M.3
David, L.L.4
-
117
-
-
0029790496
-
Crystallins from rat lens are especially susceptible to calpain-induced light scattering compared to other species
-
T.R. Shearer, M. Shih, T. Mizuno, and L.L. David Crystallins from rat lens are especially susceptible to calpain-induced light scattering compared to other species Curr. Eye Res. 15 1996 860 868
-
(1996)
Curr. Eye Res.
, vol.15
, pp. 860-868
-
-
Shearer, T.R.1
Shih, M.2
Mizuno, T.3
David, L.L.4
-
118
-
-
0031959735
-
A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant 'zonular pulverulent' cataract, on chromosome 1q
-
A. Shiels, D. Mackay, A. Ionides, V. Berry, A. Moore, and S. Bhattacharya A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant 'zonular pulverulent' cataract, on chromosome 1q Am. J. Hum. Genet. 62 1998 526 532
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 526-532
-
-
Shiels, A.1
MacKay, D.2
Ionides, A.3
Berry, V.4
Moore, A.5
Bhattacharya, S.6
-
119
-
-
0032570373
-
Cleavage of beta crystallins during maturation of bovine lens
-
M. Shih, K.J. Lampi, T.R. Shearer, and L.L. David Cleavage of beta crystallins during maturation of bovine lens Mol. Vis. 4 1998 4
-
(1998)
Mol. Vis.
, vol.4
, pp. 4
-
-
Shih, M.1
Lampi, K.J.2
Shearer, T.R.3
David, L.L.4
-
120
-
-
0032828352
-
Lens autofluorescence and light scatter in relation to the lens opacities classification system, LOCS III
-
S. Siik, L.T. Chylack Jr, J. Friend, J. Wolfe, J. Teikari, H. Nieminen, and P.J. Airaksinen Lens autofluorescence and light scatter in relation to the lens opacities classification system, LOCS III Acta Ophthalmol. Scand. 77 1999 509 514
-
(1999)
Acta Ophthalmol. Scand.
, vol.77
, pp. 509-514
-
-
Siik, S.1
Chylack Jr., L.T.2
Friend, J.3
Wolfe, J.4
Teikari, J.5
Nieminen, H.6
Airaksinen, P.J.7
-
121
-
-
0034655826
-
The non-oxidative degradation of ascorbic acid at physiological conditions
-
G.L. Simpson, and B.J. Ortwerth The non-oxidative degradation of ascorbic acid at physiological conditions Biochim. Biophys. Acta 1501 2000 12 24
-
(2000)
Biochim. Biophys. Acta
, vol.1501
, pp. 12-24
-
-
Simpson, G.L.1
Ortwerth, B.J.2
-
122
-
-
0032789443
-
Structure of the crystallins
-
C. Slingsby, and N.J. Clout Structure of the crystallins Eye 13 1999 395 402
-
(1999)
Eye
, vol.13
, pp. 395-402
-
-
Slingsby, C.1
Clout, N.J.2
-
123
-
-
0029020964
-
Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients
-
J.B. Smith, G.A. Shunshin, Y.P. Sun, L.R. Miesbauer, Z.C. Yang, Z.Y. Yhang, X.J. Zhou, J. Schwedler, and D.L. Smith Glutathione adducts, not carbamylated lysines, are the major modification of lens alpha-crystallins from renal failure patients J. Prot. Chem. 14 1995 179 188
-
(1995)
J. Prot. Chem.
, vol.14
, pp. 179-188
-
-
Smith, J.B.1
Shunshin, G.A.2
Sun, Y.P.3
Miesbauer, L.R.4
Yang, Z.C.5
Yhang, Z.Y.6
Zhou, X.J.7
Schwedler, J.8
Smith, D.L.9
-
124
-
-
0035477014
-
Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein
-
M.A. Sochaski, A.J. Jenkins, T.J. Lyons, S.R. Thorpe, and J.W. Baynes Isotope dilution gas chromatography/mass spectrometry method for the determination of methionine sulfoxide in protein Anal. Chem. 73 2001 4662 4667
-
(2001)
Anal. Chem.
, vol.73
, pp. 4662-4667
-
-
Sochaski, M.A.1
Jenkins, A.J.2
Lyons, T.J.3
Thorpe, S.R.4
Baynes, J.W.5
-
125
-
-
0021663784
-
Oxidation and cataract
-
A. Spector Oxidation and cataract Ciba Found. Symp. 106 1984 48 64
-
(1984)
Ciba Found. Symp.
, vol.106
, pp. 48-64
-
-
Spector, A.1
-
126
-
-
0019843761
-
Hydrogen peroxide and human cataract
-
A. Spector, and W.H. Garner Hydrogen peroxide and human cataract Exp. Eye Res. 33 1981 673 681
-
(1981)
Exp. Eye Res.
, vol.33
, pp. 673-681
-
-
Spector, A.1
Garner, W.H.2
-
128
-
-
6944225329
-
Lenticular levels ofamino acids and free UV filters differ significantly between normals and cataract patients
-
I.M. Streete, J.F. Jamie, and R.J.W. Truscott Lenticular levels ofamino acids and free UV filters differ significantly between normals and cataract patients Invest. Ophthalmol. Vis. Sci. 45 2004 4091 4098
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 4091-4098
-
-
Streete, I.M.1
Jamie, J.F.2
Truscott, R.J.W.3
-
129
-
-
0032412746
-
An impediment to glutathione diffusion in older normal human lenses: A possible precondition for nuclear cataract
-
M.H. Sweeney, and R.J. Truscott An impediment to glutathione diffusion in older normal human lenses: a possible precondition for nuclear cataract Exp. Eye Res. 67 1998 587 595
-
(1998)
Exp. Eye Res.
, vol.67
, pp. 587-595
-
-
Sweeney, M.H.1
Truscott, R.J.2
-
130
-
-
0029144240
-
Identification of the in vivo truncation sites at the C-terminal region of alpha-a crystallin from aged bovine and human lens
-
L.J. Takemoto Identification of the in vivo truncation sites at the C-terminal region of alpha-a crystallin from aged bovine and human lens Curr. Eye Res. 14 1995 837 841
-
(1995)
Curr. Eye Res.
, vol.14
, pp. 837-841
-
-
Takemoto, L.J.1
-
131
-
-
0017184795
-
Amino acid composition of normal and cataractous human lens proteins
-
L.J. Takemoto, and P. Azari Amino acid composition of normal and cataractous human lens proteins Exp. Eye Res. 23 1976 1 7
-
(1976)
Exp. Eye Res.
, vol.23
, pp. 1-7
-
-
Takemoto, L.J.1
Azari, P.2
-
132
-
-
0032794653
-
Epidemiology of age-related cataract
-
H. Taylor Epidemiology of age-related cataract Eye 13 1999 445 448
-
(1999)
Eye
, vol.13
, pp. 445-448
-
-
Taylor, H.1
-
133
-
-
0037377941
-
Eye care for the future: The Weisenfeld lecture
-
H. Taylor Eye care for the future: the Weisenfeld lecture Invest. Ophthalmol. Vis. Sci. 44 2003 1413 1418
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 1413-1418
-
-
Taylor, H.1
-
135
-
-
0036315485
-
Glutathione and NADH, but not ascorbate, protect lens proteins from modification by UV filters
-
L.M. Taylor, J.A. Aquilina, J.F. Jamie, and R.J.W. Truscott Glutathione and NADH, but not ascorbate, protect lens proteins from modification by UV filters Exp. Eye Res. 74 2002 503 511
-
(2002)
Exp. Eye Res.
, vol.74
, pp. 503-511
-
-
Taylor, L.M.1
Aquilina, J.A.2
Jamie, J.F.3
Truscott, R.J.W.4
-
136
-
-
0033597866
-
Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine a and the advanced Maillard reaction in aging, diabetes, and cataractogenesis
-
F. Tessier, M. Obrenovich, and V.M. Monnier Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis J. Biol. Chem. 274 1999 20796 20804
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20796-20804
-
-
Tessier, F.1
Obrenovich, M.2
Monnier, V.M.3
-
137
-
-
0036107838
-
A simplified cataract grading system
-
B. Thylefors, L.T. Chylack Jr, K. Konyama, K. Sasaki, R. Sperduto, H.R. Taylor, S. West, and W.H.O.C.G. Group A simplified cataract grading system Ophthalmic Epidemiol. 9 2002 83 95
-
(2002)
Ophthalmic Epidemiol.
, vol.9
, pp. 83-95
-
-
Thylefors, B.1
Chylack Jr., L.T.2
Konyama, K.3
Sasaki, K.4
Sperduto, R.5
Taylor, H.R.6
West, S.7
Group, W.H.O.C.G.8
-
138
-
-
0033824238
-
Age-related nuclear cataract: A lens transport problem
-
R.J. Truscott Age-related nuclear cataract: a lens transport problem Ophthalmic Res. 32 2000 185 194
-
(2000)
Ophthalmic Res.
, vol.32
, pp. 185-194
-
-
Truscott, R.J.1
-
139
-
-
0017330354
-
Changes in human lens proteins during nuclear cataract formation
-
R.J.W. Truscott, and R.C. Augusteyn Changes in human lens proteins during nuclear cataract formation Exp. Eye Res. 24 1977 159 170
-
(1977)
Exp. Eye Res.
, vol.24
, pp. 159-170
-
-
Truscott, R.J.W.1
Augusteyn, R.C.2
-
140
-
-
0017408844
-
Oxidative changes in human lens proteins during senile nuclear cataract formation
-
R.J.W. Truscott, and R.C. Augusteyn Oxidative changes in human lens proteins during senile nuclear cataract formation Biochim. Biophys. Acta 492 1977 43 52
-
(1977)
Biochim. Biophys. Acta
, vol.492
, pp. 43-52
-
-
Truscott, R.J.W.1
Augusteyn, R.C.2
-
141
-
-
0017656230
-
The state of sulphydryl groups in normal and cataractous human lenses
-
R.J.W. Truscott, and R.C. Augusteyn The state of sulphydryl groups in normal and cataractous human lenses Exp. Eye Res. 25 1977 139 148
-
(1977)
Exp. Eye Res.
, vol.25
, pp. 139-148
-
-
Truscott, R.J.W.1
Augusteyn, R.C.2
-
142
-
-
0028862098
-
Relationship between serum tryptophan and tryptophan metabolite levels after tryptophan ingestion in normal subjects and age-related cataract patients
-
R.J.W. Truscott, and A.J. Elderfield Relationship between serum tryptophan and tryptophan metabolite levels after tryptophan ingestion in normal subjects and age-related cataract patients Clin. Sci. 89 1995 591 599
-
(1995)
Clin. Sci.
, vol.89
, pp. 591-599
-
-
Truscott, R.J.W.1
Elderfield, A.J.2
-
143
-
-
0026719652
-
Identification of 3-hydroxykynurenine as the lens pigment in the gourami Trichogaster trichopterus
-
R.J.W. Truscott, J.A. Carver, A. Thorpe, and R.H. Douglas Identification of 3-hydroxykynurenine as the lens pigment in the gourami Trichogaster trichopterus Exp. Eye Res. 54 1992 1015 1017
-
(1992)
Exp. Eye Res.
, vol.54
, pp. 1015-1017
-
-
Truscott, R.J.W.1
Carver, J.A.2
Thorpe, A.3
Douglas, R.H.4
-
144
-
-
0036139647
-
Lens proteomics: The accumulation of crystallin modifications in the mouse lens with age
-
Y. Ueda, M.K. Duncan, and L.L. David Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age Invest. Ophthalmol. Vis. Sci. 43 2002 205 215
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 205-215
-
-
Ueda, Y.1
Duncan, M.K.2
David, L.L.3
-
145
-
-
0015308597
-
The human lens III some observations on the post-mortem lens
-
R. van Heyningen The human lens III some observations on the post-mortem lens Exp. Eye Res. 13 1972 155 160
-
(1972)
Exp. Eye Res.
, vol.13
, pp. 155-160
-
-
Van Heyningen, R.1
-
146
-
-
0037085277
-
Novel protein modification by kynurenine in human lenses
-
S. Vazquez, J.A. Aquilina, J.F. Jamie, M.M. Sheil, and R.J. Truscott Novel protein modification by kynurenine in human lenses J. Biol. Chem. 277 2002 4867 4873
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4867-4873
-
-
Vazquez, S.1
Aquilina, J.A.2
Jamie, J.F.3
Sheil, M.M.4
Truscott, R.J.5
-
147
-
-
0142169857
-
Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line
-
S.T. Wang-Su, A.L. McCormack, S. Yang, M.R. Hosler, A. Mixon, M.A. Riviere, P.A. Wilmarth, U.P. Andley, and D. Garland Proteome analysis of lens epithelia, fibers, and the HLE B-3 cell line Invest. Ophthalmol. Vis. Sci. 44 2003 4829 4836
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 4829-4836
-
-
Wang-Su, S.T.1
McCormack, A.L.2
Yang, S.3
Hosler, M.R.4
Mixon, A.5
Riviere, M.A.6
Wilmarth, P.A.7
Andley, U.P.8
Garland, D.9
-
148
-
-
0028674022
-
In vivo studies on the effect of UV-radiation on the eye lens in animals
-
A.R. Wegener In vivo studies on the effect of UV-radiation on the eye lens in animals Doc. Ophthalmol. 88 1994 221 232
-
(1994)
Doc. Ophthalmol.
, vol.88
, pp. 221-232
-
-
Wegener, A.R.1
-
149
-
-
0027254198
-
Oxidized amino acids in lens protein with age. Measurement of o-tyrosine and dityrosine in the aging human lens
-
M.C. Wells-Knecht, T.G. Huggins, D.G. Dyer, S.R. Thorpe, and J.W. Baynes Oxidized amino acids in lens protein with age. Measurement of o-tyrosine and dityrosine in the aging human lens J. Biol. Chem. 268 1993 12348 12352
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12348-12352
-
-
Wells-Knecht, M.C.1
Huggins, T.G.2
Dyer, D.G.3
Thorpe, S.R.4
Baynes, J.W.5
-
150
-
-
0028872768
-
Epidemiology of risk factors for age-related cataract
-
S.K. West, and C.T. Valmadrid Epidemiology of risk factors for age-related cataract Surv. Ophthalmol. 39 1995 323 334
-
(1995)
Surv. Ophthalmol.
, vol.39
, pp. 323-334
-
-
West, S.K.1
Valmadrid, C.T.2
-
151
-
-
0023225865
-
Recruitment of enzymes as lens structural proteins
-
G. Wistow, and J. Piatigorsky Recruitment of enzymes as lens structural proteins Science 236 1987 1554 1556
-
(1987)
Science
, vol.236
, pp. 1554-1556
-
-
Wistow, G.1
Piatigorsky, J.2
-
152
-
-
0035028667
-
Protein glycation: Creation of catalytic sites for free radical generation
-
M.B. Yim, H.S. Yim, C. Lee, S.O. Kang, and P.B. Chock Protein glycation: creation of catalytic sites for free radical generation Ann. NY Acad. Sci. 928 2001 48 53
-
(2001)
Ann. NY Acad. Sci.
, vol.928
, pp. 48-53
-
-
Yim, M.B.1
Yim, H.S.2
Lee, C.3
Kang, S.O.4
Chock, P.B.5
-
155
-
-
0024209292
-
The nature and properties of squirrel lens yellow pigment
-
S. Zigman, and T. Paxhia The nature and properties of squirrel lens yellow pigment Exp. Eye Res. 47 1988 819 824
-
(1988)
Exp. Eye Res.
, vol.47
, pp. 819-824
-
-
Zigman, S.1
Paxhia, T.2
|