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Volumn 214, Issue 1, 2000, Pages 86-104

The ageing lens

Author keywords

Ageing lens; Cataract; Crystallins; Lens epithelium; Lens fibres; Presbyopia; Sutures

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA CRYSTALLIN; ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; CAROTENOID; CATALASE; COMPLEMENTARY DNA; CORTICOTROPIN; DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MESSENGER RNA; METALLOTHIONEIN; MOLYBDENUM; MULTIVITAMIN; NICOTINIC ACID; OXYGEN RADICAL; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOTOSENSITIZING AGENT; PROTEIN C FOS; PROTEIN C JUN; RETINOL; RNA; SELENIUM; UBIQUITIN PROTEIN LIGASE; UNINDEXED DRUG; ZINC;

EID: 0033981119     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000027475     Document Type: Review
Times cited : (240)

References (129)
  • 1
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS: The serial cultivation of human diploid cell strains. Exp Cell Res 1961;25:585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 2
    • 0002157835 scopus 로고
    • The cellular basis for biological ageing
    • Finch CE, Hayflick L (eds): New York, Van Nostrand Reinhold
    • Hayflick L: The cellular basis for biological ageing; in Finch CE, Hayflick L (eds): Handbook of the Biology of Ageing. New York, Van Nostrand Reinhold, 1977.
    • (1977) Handbook of the Biology of Ageing
    • Hayflick, L.1
  • 3
    • 0017202906 scopus 로고
    • Experimental studies on cataract. Proctor lecture
    • van Heyningen R: Experimental studies on cataract. Proctor lecture. Invest Ophthalmol 1976;15:685-697.
    • (1976) Invest Ophthalmol , vol.15 , pp. 685-697
    • Van Heyningen, R.1
  • 4
    • 0023632660 scopus 로고
    • Morphology of the aging human lens. I. Biomicroscopy and biometrics
    • Willekens B, Kappelhof J, Vrensen G: Morphology of the aging human lens. I. Biomicroscopy and biometrics. Lens Res 1987;4:207-230.
    • (1987) Lens Res , vol.4 , pp. 207-230
    • Willekens, B.1    Kappelhof, J.2    Vrensen, G.3
  • 5
    • 0022895163 scopus 로고
    • Human fetal lens: Wet and dry weight with increasing gestational age
    • Bours J, Födisch HJ: Human fetal lens: Wet and dry weight with increasing gestational age. Ophthalmic Res 1986;18:363-368.
    • (1986) Ophthalmic Res , vol.18 , pp. 363-368
    • Bours, J.1    Födisch, H.J.2
  • 6
    • 0015308597 scopus 로고
    • The human lens. III. Some observations on the post-mortem lens
    • van Heyningen R: The human lens. III. Some observations on the post-mortem lens. Exp Eye Res 1972;13:155-160.
    • (1972) Exp Eye Res , vol.13 , pp. 155-160
    • Van Heyningen, R.1
  • 8
    • 0344867718 scopus 로고
    • Eye length in congenital cataracts
    • Cotlier E, Lambert S, Taylor D (eds): Medical Intelligence Unit Series. Austin, Landes
    • Manzitti E, Damel A, Gamio S, Benozzi J: Eye length in congenital cataracts; in Cotlier E, Lambert S, Taylor D (eds): Congenital Cataracts. Medical Intelligence Unit Series. Austin, Landes, 1994, pp 251-259.
    • (1994) Congenital Cataracts , pp. 251-259
    • Manzitti, E.1    Damel, A.2    Gamio, S.3    Benozzi, J.4
  • 10
  • 11
    • 0023676121 scopus 로고
    • Central compaction in the process of lens growth as indicated by lamellar cataract
    • Brown NAP, Sparrow JM, Bron AJ: Central compaction in the process of lens growth as indicated by lamellar cataract. Br J Ophthalmol 1988;72:538-544.
    • (1988) Br J Ophthalmol , vol.72 , pp. 538-544
    • Brown, N.A.P.1    Sparrow, J.M.2    Bron, A.J.3
  • 12
    • 0028000112 scopus 로고
    • The zones of discontinuity in the human lens: Development and distribution with age
    • Koretz JF, Cook CA, Kuszak JR: The zones of discontinuity in the human lens: Development and distribution with age. Vision Res 1994;34: 2955-2962.
    • (1994) Vision Res , vol.34 , pp. 2955-2962
    • Koretz, J.F.1    Cook, C.A.2    Kuszak, J.R.3
  • 14
    • 0001858228 scopus 로고
    • The 'lens paradox' and image formation in accommodating human eyes
    • Duncan G (ed): Rijswijk, Eurage
    • Koretz J, Handelman GH: The 'lens paradox' and image formation in accommodating human eyes; in Duncan G (ed): The Lens: Transparency and Cataract. Rijswijk, Eurage, 1986, pp 57-64.
    • (1986) The Lens: Transparency and Cataract , pp. 57-64
    • Koretz, J.1    Handelman, G.H.2
  • 15
    • 0023908859 scopus 로고
    • Nondestructive method of constructing three dimensional gradient index models for crystalline lenses. 1. Theory and experiment
    • Pierscionek BK, Chan DYC, Ennis JP, Smith G, Augusteyn RC: Nondestructive method of constructing three dimensional gradient index models for crystalline lenses. 1. Theory and experiment. Am J Optom Physiol Opt 1988;65: 481-491.
    • (1988) Am J Optom Physiol Opt , vol.65 , pp. 481-491
    • Pierscionek, B.K.1    Chan, D.Y.C.2    Ennis, J.P.3    Smith, G.4    Augusteyn, R.C.5
  • 16
    • 0025876037 scopus 로고
    • Age-related changes in local water and protein content of human eye lenses measured by Raman microspectroscopy
    • Siebinga I, Vrensen GFJM, de Mul FFM, Greve J: Age-related changes in local water and protein content of human eye lenses measured by Raman microspectroscopy. Exp Eye Res 1991;53:233-239.
    • (1991) Exp Eye Res , vol.53 , pp. 233-239
    • Siebinga, I.1    Vrensen, G.F.J.M.2    De Mul, F.F.M.3    Greve, J.4
  • 17
    • 0027053319 scopus 로고
    • Changes in light scatter and width measurements from the human lens cortex with age
    • Smith GTH, Smith RC, Brown NAP, Bron AJ, Harris ML: Changes in light scatter and width measurements from the human lens cortex with age. Eye 1992;6:55-59.
    • (1992) Eye , vol.6 , pp. 55-59
    • Smith, G.T.H.1    Smith, R.C.2    Brown, N.A.P.3    Bron, A.J.4    Harris, M.L.5
  • 19
    • 0038089257 scopus 로고
    • Electron microscopic observations of the crystalline lens. Electron microscopy of the visual system: The anterior segment of the eye
    • Kuszak JR, Peterson KL, Brown HG: Electron microscopic observations of the crystalline lens. Electron microscopy of the visual system: The anterior segment of the eye (special issue). J Electron Microsc 1992;1:1.
    • (1992) J Electron Microsc , vol.1 , Issue.SPEC. ISSUE , pp. 1
    • Kuszak, J.R.1    Peterson, K.L.2    Brown, H.G.3
  • 20
    • 0025860445 scopus 로고
    • Lens optical quality is a direct function of lens sutural architecture
    • published erratum appears in Invest Ophthalmol Vis Sci 1992;32(6):2076-2077
    • Kuszak JR, Sivak JG, Weerheim JA: Lens optical quality is a direct function of lens sutural architecture (published erratum appears in Invest Ophthalmol Vis Sci 1992;32(6):2076-2077) Invest Ophthalmol Vis Sci 1991;32(7): 2119-2129.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , Issue.7 , pp. 2119-2129
    • Kuszak, J.R.1    Sivak, J.G.2    Weerheim, J.A.3
  • 21
    • 34548521640 scopus 로고
    • Specular microscopy of the lens
    • Bron AJ, Lambert SR: Specular microscopy of the lens (abstract). Ophthalmic Res 1984;16: 209.
    • (1984) Ophthalmic Res , vol.16 , pp. 209
    • Bron, A.J.1    Lambert, S.R.2
  • 24
    • 0015374162 scopus 로고
    • The postnatal growth of the capsule of the human crystalline lens
    • Fisher RF, Pettet BE: The postnatal growth of the capsule of the human crystalline lens. J Anal 1972;112:207-214.
    • (1972) J Anal , vol.112 , pp. 207-214
    • Fisher, R.F.1    Pettet, B.E.2
  • 25
    • 0016264211 scopus 로고
    • Ultrastructural changes in the normal human lens capsule form birth to old age
    • Seland JH: Ultrastructural changes in the normal human lens capsule form birth to old age. Acta Ophthalmol 1974;52:688-706.
    • (1974) Acta Ophthalmol , vol.52 , pp. 688-706
    • Seland, J.H.1
  • 26
    • 0031045155 scopus 로고    scopus 로고
    • Biomechanical characteristics of the human anterior lens capsule in relation to age
    • Krag S, Olsen T, Andreassen T: Biomechanical characteristics of the human anterior lens capsule in relation to age. Invest Ophthalmol Vis Sci 1997;38:357-363.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 357-363
    • Krag, S.1    Olsen, T.2    Andreassen, T.3
  • 28
    • 0029986646 scopus 로고    scopus 로고
    • Lens epithelial cell apoptosis is an early event in the development of UVB-induced cataract
    • Li WC, Spector A: Lens epithelial cell apoptosis is an early event in the development of UVB-induced cataract. Free Radic Biol Med 1996;20:301-311.
    • (1996) Free Radic Biol Med , vol.20 , pp. 301-311
    • Li, W.C.1    Spector, A.2
  • 29
    • 0006921435 scopus 로고    scopus 로고
    • The lens epithelium, apoptosis and cataract formation
    • Li DWC: The lens epithelium, apoptosis and cataract formation. Nova Acta Leopoldina 1997;75:81-108.
    • (1997) Nova Acta Leopoldina , vol.75 , pp. 81-108
    • Li, D.W.C.1
  • 31
    • 0017663401 scopus 로고
    • Three-dimensional architecture of the suspensory apparatus of the lens of the Rhesus monkey
    • Farnsworth PN, Burke PA: Three-dimensional architecture of the suspensory apparatus of the lens of the Rhesus monkey. Exp Eye Res 1977; 25:563-576.
    • (1977) Exp Eye Res , vol.25 , pp. 563-576
    • Farnsworth, P.N.1    Burke, P.A.2
  • 32
    • 0018376365 scopus 로고
    • Anterior zonular shifts with age
    • Farnsworth PH, Shyne SE: Anterior zonular shifts with age. Exp Eye Res 1979;28:291-297.
    • (1979) Exp Eye Res , vol.28 , pp. 291-297
    • Farnsworth, P.H.1    Shyne, S.E.2
  • 33
    • 0031914557 scopus 로고    scopus 로고
    • Anterior shift of zonular insertion onto the anterior surface of human crystalline lens with age
    • Sakabe I, Oshika T, Lim SJ, Apple DJ: Anterior shift of zonular insertion onto the anterior surface of human crystalline lens with age. Ophthalmology 1998;105:295-299.
    • (1998) Ophthalmology , vol.105 , pp. 295-299
    • Sakabe, I.1    Oshika, T.2    Lim, S.J.3    Apple, D.J.4
  • 34
    • 53849149404 scopus 로고
    • The elastic constants of the human lens capsule
    • Fisher RF: The elastic constants of the human lens capsule. J Physiol 1969;201:1-19.
    • (1969) J Physiol , vol.201 , pp. 1-19
    • Fisher, R.F.1
  • 35
    • 0014478243 scopus 로고
    • The significance and shape of the lens and capsular energy changes in accommodation
    • Fisher RF: The significance and shape of the lens and capsular energy changes in accommodation. J Physiol 1969;201:21-47.
    • (1969) J Physiol , vol.201 , pp. 21-47
    • Fisher, R.F.1
  • 36
    • 0018904741 scopus 로고
    • Changes in chemical composition of anterior lens capsules of cataractous human eyes as a function of age
    • Peczon BD, Peczon JD, Cintron C, Hudson BG: Changes in chemical composition of anterior lens capsules of cataractous human eyes as a function of age. Exp Eye Res 1980;30:155-165.
    • (1980) Exp Eye Res , vol.30 , pp. 155-165
    • Peczon, B.D.1    Peczon, J.D.2    Cintron, C.3    Hudson, B.G.4
  • 37
    • 0014618870 scopus 로고
    • Accumulation of fibrillar protein in the aging human lens capsule
    • Dark AJ, Streeten BW, Jones DB: Accumulation of fibrillar protein in the aging human lens capsule. Arch Ophthalmol 1969;82:815-821.
    • (1969) Arch Ophthalmol , vol.82 , pp. 815-821
    • Dark, A.J.1    Streeten, B.W.2    Jones, D.B.3
  • 38
    • 0018381550 scopus 로고
    • A comparison of human lens epithelial cells in situ and in vitro in relation to aging: An ultrastructural study
    • Perry MM, Tassin J, Courtois YA: A comparison of human lens epithelial cells in situ and in vitro in relation to aging: An ultrastructural study. Exp Eye Res 1979;28:327-341.
    • (1979) Exp Eye Res , vol.28 , pp. 327-341
    • Perry, M.M.1    Tassin, J.2    Courtois, Y.A.3
  • 39
    • 0021019253 scopus 로고
    • Age-related changes in non-enzymatic glycosylation of human basement membranes
    • Cohen MP, Yu-Vu V: Age-related changes in non-enzymatic glycosylation of human basement membranes. Exp Gerontol 1983;18:461-469.
    • (1983) Exp Gerontol , vol.18 , pp. 461-469
    • Cohen, M.P.1    Yu-Vu, V.2
  • 40
    • 0027364874 scopus 로고
    • Chemistry of collagen cross-links: Glucose-mediated covalent cross-linking of type-IV collagen in lens capsules
    • Bailey AJ, Sims TJ, Avery NC, Miles CA: Chemistry of collagen cross-links: Glucose-mediated covalent cross-linking of type-IV collagen in lens capsules. Biochem J 1993;296:489-496.
    • (1993) Biochem J , vol.296 , pp. 489-496
    • Bailey, A.J.1    Sims, T.J.2    Avery, N.C.3    Miles, C.A.4
  • 41
    • 0020262496 scopus 로고
    • Visible changes of the lens with age
    • Niesel P: Visible changes of the lens with age. Trans Ophthalmol Soc UK 1982;102:327-330.
    • (1982) Trans Ophthalmol Soc UK , vol.102 , pp. 327-330
    • Niesel, P.1
  • 42
    • 34548521141 scopus 로고
    • Studien über die Alterskernstreifen der Linse
    • Goldmann H: Studien über die Alterskernstreifen der Linse. Arch Augenheilk 1937;110:405-414.
    • (1937) Arch Augenheilk , vol.110 , pp. 405-414
    • Goldmann, H.1
  • 43
    • 84979134790 scopus 로고
    • Are the discontinuity zones of the crystalline lens iso-indicial surfaces?
    • Huggert A: Are the discontinuity zones of the crystalline lens iso-indicial surfaces? Acta Ophthalmol 1946;24:417-421.
    • (1946) Acta Ophthalmol , vol.24 , pp. 417-421
    • Huggert, A.1
  • 48
    • 0027057819 scopus 로고
    • Mitochondrial dynamics in differentiating fiber cells of the mammalian lens
    • Bassnett S: Mitochondrial dynamics in differentiating fiber cells of the mammalian lens. Curr Eye Res 1992;11:1227-1232.
    • (1992) Curr Eye Res , vol.11 , pp. 1227-1232
    • Bassnett, S.1
  • 49
    • 0030771954 scopus 로고    scopus 로고
    • Fiber cell denucleation in the primate lens
    • Bassnett S: Fiber cell denucleation in the primate lens. Invest Ophthalmol Vis Sci 1997;38 (9):1678-1687.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , Issue.9 , pp. 1678-1687
    • Bassnett, S.1
  • 50
    • 0026774623 scopus 로고
    • Coincident loss of mitochondria and nuclei during lens fiber differentiation
    • Bassnett S, Beebe DC: Coincident loss of mitochondria and nuclei during lens fiber differentiation. Dev Dyn 1992;194:85-93.
    • (1992) Dev Dyn , vol.194 , pp. 85-93
    • Bassnett, S.1    Beebe, D.C.2
  • 51
    • 0031002566 scopus 로고    scopus 로고
    • Chromatin degradation in differentiating fiber cells of the eye lens
    • Bassnett S, Mataic D: Chromatin degradation in differentiating fiber cells of the eye lens. J Cell Biol 1997;137:37-49.
    • (1997) J Cell Biol , vol.137 , pp. 37-49
    • Bassnett, S.1    Mataic, D.2
  • 52
    • 0029812256 scopus 로고    scopus 로고
    • Calcium distribution in the human eye lens
    • Vrensen GFJM, de Wolf A: Calcium distribution in the human eye lens. Ophthalmic Res 1996;28(suppl 2):78-85.
    • (1996) Ophthalmic Res , vol.28 , Issue.2 SUPPL. , pp. 78-85
    • Vrensen, G.F.J.M.1    De Wolf, A.2
  • 53
    • 0038427920 scopus 로고
    • Growth of the human crystalline lens in childhood
    • Proceedings of the Xth ISER Meeting, Stresa, Italy
    • Forbes JE, Holden R, Harris M, et al: Growth of the human crystalline lens in childhood. Proceedings of the Xth ISER Meeting, Stresa, Italy. Exp Eye Res 1992;55:172.
    • (1992) Exp Eye Res , vol.55 , pp. 172
    • Forbes, J.E.1    Holden, R.2    Harris, M.3
  • 54
  • 56
    • 0005832406 scopus 로고
    • Der Ziliarkörper als funktionelles System
    • Rohen JW: Der Ziliarkörper als funktionelles System. Morph Jahrb 1952;92:415-440.
    • (1952) Morph Jahrb , vol.92 , pp. 415-440
    • Rohen, J.W.1
  • 57
    • 0014189384 scopus 로고
    • A photographic study of accommodative mechanims: Changes in the lens nucleus during accommodation
    • Patnaik B: A photographic study of accommodative mechanims: Changes in the lens nucleus during accommodation. Invest Ophthalmol 1967;6:601-611.
    • (1967) Invest Ophthalmol , vol.6 , pp. 601-611
    • Patnaik, B.1
  • 58
    • 0015612084 scopus 로고
    • The change in shape and internal form of the lens of the eye on accommodation
    • Brown NAP: The change in shape and internal form of the lens of the eye on accommodation. Exp Eye Res 1973;15:441-459.
    • (1973) Exp Eye Res , vol.15 , pp. 441-459
    • Brown, N.A.P.1
  • 59
    • 0021682024 scopus 로고
    • Analysis of human crystalline lens curvature as a function of accommodative state and age
    • Koretz J, Handelman G, Brown N: Analysis of human crystalline lens curvature as a function of accommodative state and age. Vision Res 1984;24:1141-1151.
    • (1984) Vision Res , vol.24 , pp. 1141-1151
    • Koretz, J.1    Handelman, G.2    Brown, N.3
  • 60
    • 0024818078 scopus 로고
    • Accommodation and presbyopia in the human eye - Aging of the anterior segment
    • Koretz JF, Kaufman PL, Neider MW, Goeckner PA: Accommodation and presbyopia in the human eye - Aging of the anterior segment. Vision Res 1989;29:1685-1692.
    • (1989) Vision Res , vol.29 , pp. 1685-1692
    • Koretz, J.F.1    Kaufman, P.L.2    Neider, M.W.3    Goeckner, P.A.4
  • 61
    • 0030130847 scopus 로고    scopus 로고
    • Age-related changes in the accomodation mechanism
    • Beers APA, van der Heijde GL: Age-related changes in the accomodation mechanism. Optorn Vis Sci 1996;74:235-242.
    • (1996) Optorn Vis Sci , vol.74 , pp. 235-242
    • Beers, A.P.A.1    Van Der Heijde, G.L.2
  • 62
    • 0014976536 scopus 로고
    • The elastic constant of the human lens
    • Fisher RF: The elastic constant of the human lens. J Physiol 1971;212:147-180.
    • (1971) J Physiol , vol.212 , pp. 147-180
    • Fisher, R.F.1
  • 63
    • 0015584189 scopus 로고
    • Presbyopia and the changes with age in the human crystalline lens
    • Fisher RF: Presbyopia and the changes with age in the human crystalline lens. J Physiol 1973;228:765-779.
    • (1973) J Physiol , vol.228 , pp. 765-779
    • Fisher, R.F.1
  • 64
    • 0015867869 scopus 로고
    • Presbyopia and the water content of the human crystalline lens
    • Lond
    • Fisher RF, Pettet BE: Presbyopia and the water content of the human crystalline lens. J Physiol (Lond) 1973;234:443-447.
    • (1973) J Physiol , vol.234 , pp. 443-447
    • Fisher, R.F.1    Pettet, B.E.2
  • 65
    • 0017652313 scopus 로고
    • The force of contraction of the human ciliary muscle during accommodation
    • Fisher RF: The force of contraction of the human ciliary muscle during accommodation. J Physiol 1977;270:51-74.
    • (1977) J Physiol , vol.270 , pp. 51-74
    • Fisher, R.F.1
  • 66
    • 0025882397 scopus 로고
    • Elasticity of tissues involved in accomodation
    • van Alphen GWHM, Graebel WP: Elasticity of tissues involved in accomodation. Vision Res 1991;31:1417-1438.
    • (1991) Vision Res , vol.31 , pp. 1417-1438
    • Van Alphen, G.W.H.M.1    Graebel, W.P.2
  • 67
    • 0017555595 scopus 로고
    • The elasticity of sclera and choroid of the human eye, and its implications on scleral rigidity and accommodation
    • Graebel WP, van Alphen GWHM: The elasticity of sclera and choroid of the human eye, and its implications on scleral rigidity and accommodation. J Biomech Eng 1977;99:203-208.
    • (1977) J Biomech Eng , vol.99 , pp. 203-208
    • Graebel, W.P.1    Van Alphen, G.W.H.M.2
  • 68
    • 2342462437 scopus 로고
    • The structure of the human ciliary muscle, its changes during life and its influence on accommodation
    • Stiev E: The structure of the human ciliary muscle, its changes during life and its influence on accommodation. Anat Anz 1949;97:69-79.
    • (1949) Anat Anz , vol.97 , pp. 69-79
    • Stiev, E.1
  • 69
    • 0026543420 scopus 로고
    • Age-related changes of the human ciliary muscle. A quantitative morphometric study
    • Tamm S, Tamm E, Rohen JW: Age-related changes of the human ciliary muscle. A quantitative morphometric study. Mech Ageing Dev 1992;62:209-221.
    • (1992) Mech Ageing Dev , vol.62 , pp. 209-221
    • Tamm, S.1    Tamm, E.2    Rohen, J.W.3
  • 70
    • 0002306564 scopus 로고
    • Biochemistry of lens plasma membranes and cytoskeleton
    • Maisel H (ed): New York, Dekker
    • Alcala J, Maisel H: Biochemistry of lens plasma membranes and cytoskeleton; in Maisel H (ed): The Ocular Lens: Strucutre, Function and Pathology. New York, Dekker, 1985, pp 169-222
    • (1985) The Ocular Lens: Strucutre, Function and Pathology , pp. 169-222
    • Alcala, J.1    Maisel, H.2
  • 71
    • 0029986547 scopus 로고    scopus 로고
    • Aging affects the conformation of cholesterol in the human eye lens
    • Duindam JJ, Vrensen GFJM, Otto C, Greve J: Aging affects the conformation of cholesterol in the human eye lens. Ophthalmic Res 1996; 28(suppl 1):86-91.
    • (1996) Ophthalmic Res , vol.28 , Issue.1 SUPPL. , pp. 86-91
    • Duindam, J.J.1    Vrensen, G.F.J.M.2    Otto, C.3    Greve, J.4
  • 72
    • 0014824233 scopus 로고
    • Reversible binding of soluble lens proteins to lens fibre ghosts
    • Maraini G, Fasella P: Reversible binding of soluble lens proteins to lens fibre ghosts. Exp Eye Res 1970;10:133-139.
    • (1970) Exp Eye Res , vol.10 , pp. 133-139
    • Maraini, G.1    Fasella, P.2
  • 73
    • 0015084319 scopus 로고
    • Selective binding of aged a-crystallin to lens fibre ghosts
    • Bracchi PG, Carta F, Fasella P, Maraini G: Selective binding of aged a-crystallin to lens fibre ghosts. Exp Eye Res 1971;12:151-154.
    • (1971) Exp Eye Res , vol.12 , pp. 151-154
    • Bracchi, P.G.1    Carta, F.2    Fasella, P.3    Maraini, G.4
  • 74
    • 0017861922 scopus 로고
    • Lens membranes. IV. Preparative isolation and characterization of membranes and various membrane proteins from calf lens
    • Broekhuyse RM, Kuhlmann ED: Lens membranes. IV. Preparative isolation and characterization of membranes and various membrane proteins from calf lens. Exp Eye Res 1978;26:305-320.
    • (1978) Exp Eye Res , vol.26 , pp. 305-320
    • Broekhuyse, R.M.1    Kuhlmann, E.D.2
  • 75
    • 0025018042 scopus 로고
    • Immuno-cytochemical evidence for an actin-myosin system in lens epithelial cells
    • Rafferty NS, Scholz DL, Goldberg M, Lewyckyj M: Immuno-cytochemical evidence for an actin-myosin system in lens epithelial cells. Exp Eye Res 1990;51:591-600.
    • (1990) Exp Eye Res , vol.51 , pp. 591-600
    • Rafferty, N.S.1    Scholz, D.L.2    Goldberg, M.3    Lewyckyj, M.4
  • 76
    • 0024362019 scopus 로고
    • Comparative study of actin filament patterns in lens epithelial cells. Are these determined by the mechanism of lens accommodation?
    • Rafferty NS, Scholz DL: Comparative study of actin filament patterns in lens epithelial cells. Are these determined by the mechanism of lens accommodation? Curr Eye Res 1989;8:569-579.
    • (1989) Curr Eye Res , vol.8 , pp. 569-579
    • Rafferty, N.S.1    Scholz, D.L.2
  • 77
    • 0022336641 scopus 로고
    • Spatial and temporal mapping of the age-related changes in human lens crystallins
    • McFall-Ngai MJ, Ding LL, Takemoto LJ, Horowitz J: Spatial and temporal mapping of the age-related changes in human lens crystallins. Exp Eye Res 1985;41:745-758.
    • (1985) Exp Eye Res , vol.41 , pp. 745-758
    • McFall-Ngai, M.J.1    Ding, L.L.2    Takemoto, L.J.3    Horowitz, J.4
  • 78
    • 0014787125 scopus 로고
    • Free and protein bound glutathione in normal and cataractous human lenses
    • Harding JJ: Free and protein bound glutathione in normal and cataractous human lenses. Biochem J 1970;117:957-960.
    • (1970) Biochem J , vol.117 , pp. 957-960
    • Harding, J.J.1
  • 79
    • 0023187366 scopus 로고
    • Watersoluble and -insoluble crystallins of the developing human fetal lens, analyzed by agarose/polyacrylamide thin-layer isoelectric focusing
    • Ahrend MHJ, Bours J, Födisch HJ: Watersoluble and -insoluble crystallins of the developing human fetal lens, analyzed by agarose/polyacrylamide thin-layer isoelectric focusing. Ophthalmic Res 1987;19:150-156.
    • (1987) Ophthalmic Res , vol.19 , pp. 150-156
    • Ahrend, M.H.J.1    Bours, J.2    Födisch, H.J.3
  • 80
    • 0022312178 scopus 로고
    • Ontogeny of human lens crystallins
    • Thomson JA, Augusteyn RC: Ontogeny of human lens crystallins. Exp Eye Res 1985;40: 393-410.
    • (1985) Exp Eye Res , vol.40 , pp. 393-410
    • Thomson, J.A.1    Augusteyn, R.C.2
  • 81
    • 0001001048 scopus 로고
    • Species specificity of the crystallins and the albuminoid of the ageing lens
    • Bours J: Species specificity of the crystallins and the albuminoid of the ageing lens. Comp Biochem Physiol 1980;65:215-222.
    • (1980) Comp Biochem Physiol , vol.65 , pp. 215-222
    • Bours, J.1
  • 83
    • 0021789405 scopus 로고
    • Major intrinsic polypeptide (MIP26K) from lens membrane: Reconstitution into vesicles and inhibition of channel forming activity by peptide antiserum
    • Gooden M, Rintoul D, Takehana M, Takemoto L: Major intrinsic polypeptide (MIP26K) from lens membrane: Reconstitution into vesicles and inhibition of channel forming activity by peptide antiserum. Biochem Biophys Res Commun 1985;128:993-999.
    • (1985) Biochem Biophys Res Commun , vol.128 , pp. 993-999
    • Gooden, M.1    Rintoul, D.2    Takehana, M.3    Takemoto, L.4
  • 84
    • 0027208037 scopus 로고
    • Apparent coordination of plasma membrane component synthesis in the lens
    • Cenedella RJ: Apparent coordination of plasma membrane component synthesis in the lens. Invest Ophthalmol Vis Sci 1993;34(7):2186-2195.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , Issue.7 , pp. 2186-2195
    • Cenedella, R.J.1
  • 85
    • 0031975419 scopus 로고    scopus 로고
    • Cholesterol, phospholipid, and protein changes in focal opacities in the human eye lens
    • Duindam JJ, Vrensen GFJM, Otto C, Greve J: Cholesterol, phospholipid, and protein changes in focal opacities in the human eye lens. Invest Ophthalmol Vis Sci 1998;39:94-103.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 94-103
    • Duindam, J.J.1    Vrensen, G.F.J.M.2    Otto, C.3    Greve, J.4
  • 86
    • 0031454950 scopus 로고    scopus 로고
    • Effect of aging on the chaperone-like function of human α-crystallin assessed by three methods
    • Derham BK, Harding JJ: Effect of aging on the chaperone-like function of human α-crystallin assessed by three methods. Biochem J 1997; 328:763-768.
    • (1997) Biochem J , vol.328 , pp. 763-768
    • Derham, B.K.1    Harding, J.J.2
  • 87
    • 0030813865 scopus 로고    scopus 로고
    • The effects of ageing on the chaperone-like function of rabbit α-crystallin, comparing three methods of assays
    • Derham BK, Harding JJ: The effects of ageing on the chaperone-like function of rabbit α-crystallin, comparing three methods of assays. Biochim Biophys Acta 1997;1336:187-194.
    • (1997) Biochim Biophys Acta , vol.1336 , pp. 187-194
    • Derham, B.K.1    Harding, J.J.2
  • 88
    • 0022921475 scopus 로고
    • Age-dependent changes in the heat-stable crystallin βBp, of the human lens
    • McFall-Ngai M, Horowitz J, Ding LL, Lacey L: Age-dependent changes in the heat-stable crystallin βBp, of the human lens. Curr Eye Res 1986;5:387-394.
    • (1986) Curr Eye Res , vol.5 , pp. 387-394
    • McFall-Ngai, M.1    Horowitz, J.2    Ding, L.L.3    Lacey, L.4
  • 89
    • 0023264813 scopus 로고
    • Cleavage from the N-terminal region of βBp crystallin during aging of the human lens
    • Takemoto L, Takemoto D, Brown G, Takehana M, Smith J, Horwitz J: Cleavage from the N-terminal region of βBp crystallin during aging of the human lens. Exp Eye Res 1987;45: 385-392.
    • (1987) Exp Eye Res , vol.45 , pp. 385-392
    • Takemoto, L.1    Takemoto, D.2    Brown, G.3    Takehana, M.4    Smith, J.5    Horwitz, J.6
  • 91
    • 0016706399 scopus 로고
    • Changes in proteins of the human lens in development and aging
    • Dilley KJ, Harding JJ: Changes in proteins of the human lens in development and aging. Biochim Biophys Acta 1975;386:391-408.
    • (1975) Biochim Biophys Acta , vol.386 , pp. 391-408
    • Dilley, K.J.1    Harding, J.J.2
  • 93
    • 0032128077 scopus 로고    scopus 로고
    • Age-related changes in human lens crystallins identified by HPLC and mass spectrometry
    • Ma Z, Hanson SRA, Lampi K, David LL, Smith DL, Smith JB: Age-related changes in human lens crystallins identified by HPLC and mass spectrometry. Exp Eye Res 1998;67:21-30.
    • (1998) Exp Eye Res , vol.67 , pp. 21-30
    • Ma, Z.1    Hanson, S.R.A.2    Lampi, K.3    David, L.L.4    Smith, D.L.5    Smith, J.B.6
  • 94
    • 0028293240 scopus 로고
    • Characterization of the α-γ and α-β complex: Evidence for an 'in vivo' functional role of α-crystallin as a molecular chaperone
    • Boyle D, Takemoto L: Characterization of the α-γ and α-β complex: Evidence for an 'in vivo' functional role of α-crystallin as a molecular chaperone. Exp Eye Res 1994;58:9-16.
    • (1994) Exp Eye Res , vol.58 , pp. 9-16
    • Boyle, D.1    Takemoto, L.2
  • 95
    • 0019843761 scopus 로고
    • Hydrogen peroxide and human cataract
    • Spector A, Garner WH: Hydrogen peroxide and human cataract. Exp Eye Res 1981;33: 673-681.
    • (1981) Exp Eye Res , vol.33 , pp. 673-681
    • Spector, A.1    Garner, W.H.2
  • 96
    • 0033597823 scopus 로고    scopus 로고
    • Identification of glutathionyl-3-hydroxykynurenine glucoside as a novel fluorophore associated with aging of the human lens
    • Garner B, Vazquez S, Griffith R, Lindner RA, Carver JA, Truscott RJW: Identification of glutathionyl-3-hydroxykynurenine glucoside as a novel fluorophore associated with aging of the human lens. J Biol Chem 1999; 274:20847-20854.
    • (1999) J Biol Chem , vol.274 , pp. 20847-20854
    • Garner, B.1    Vazquez, S.2    Griffith, R.3    Lindner, R.A.4    Carver, J.A.5    Truscott, R.J.W.6
  • 97
    • 0022885867 scopus 로고
    • Activity of glutathione peroxidase and glutathione reductase in the human lens related to age
    • Rathbun WB, Bovis MG: Activity of glutathione peroxidase and glutathione reductase in the human lens related to age. Curr Eye Res 1986;5:381-385.
    • (1986) Curr Eye Res , vol.5 , pp. 381-385
    • Rathbun, W.B.1    Bovis, M.G.2
  • 98
    • 0024313946 scopus 로고
    • Physiologic changes of lens transparency during ageing: A Sche impflug photography study
    • Eckerskorn U, Kokkas K, Hockwin O, Laser H, Janke M: Physiologic changes of lens transparency during ageing: A Sche impflug photography study. Dev Ophthalmol 1989; 17:72-74.
    • (1989) Dev Ophthalmol , vol.17 , pp. 72-74
    • Eckerskorn, U.1    Kokkas, K.2    Hockwin, O.3    Laser, H.4    Janke, M.5
  • 99
    • 0015022316 scopus 로고
    • Theory of transparency of the eye
    • Benedek GB: Theory of transparency of the eye. Appl Opt 1971:10:459-473.
    • (1971) Appl Opt , vol.10 , pp. 459-473
    • Benedek, G.B.1
  • 101
    • 0015577189 scopus 로고
    • On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses
    • Jedziniak JA, Kinoshita JH, Yates EM, Hocker LO, Benedek GB: On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses. Exp Eye Res 1973;15: 185-192.
    • (1973) Exp Eye Res , vol.15 , pp. 185-192
    • Jedziniak, J.A.1    Kinoshita, J.H.2    Yates, E.M.3    Hocker, L.O.4    Benedek, G.B.5
  • 102
    • 0015715696 scopus 로고
    • Disulphide cross-linked protein of high molecular weight in human cataractous lens
    • Harding JJ: Disulphide cross-linked protein of high molecular weight in human cataractous lens. Exp Eye Res 1973;17:377-383.
    • (1973) Exp Eye Res , vol.17 , pp. 377-383
    • Harding, J.J.1
  • 105
    • 0025190906 scopus 로고
    • Nonenzymatic glycosylation of protein does not increase with age in normal human lenses
    • Patrick JS, Thorpe SR, Baynes JW: Nonenzymatic glycosylation of protein does not increase with age in normal human lenses. J Gerontol 1990;45:B18-B23.
    • (1990) J Gerontol , vol.45
    • Patrick, J.S.1    Thorpe, S.R.2    Baynes, J.W.3
  • 106
    • 0024407936 scopus 로고
    • Oxidation of glycated proteins: Age-dependent accumulation of NE-(carboxymethyl)lysine in lens protein
    • Dunn JA, Patrick JS, Thorpe SR, Baynes JW: Oxidation of glycated proteins: Age-dependent accumulation of NE-(carboxymethyl)lysine in lens protein. Biochemistry 1989;28: 9464-9468.
    • (1989) Biochemistry , vol.28 , pp. 9464-9468
    • Dunn, J.A.1    Patrick, J.S.2    Thorpe, S.R.3    Baynes, J.W.4
  • 107
    • 0015216149 scopus 로고
    • Fluorescent glucoside in the human lens
    • van Heyningen R: Fluorescent glucoside in the human lens. Nature 1971;230:393-394.
    • (1971) Nature , vol.230 , pp. 393-394
    • Van Heyningen, R.1
  • 109
    • 0019444732 scopus 로고
    • Spectrophotometric estimation of 3-OH L-kynurenine O-beta-glucoside in the human lens
    • Bando M, Nakajima A, Satoh K: Spectrophotometric estimation of 3-OH L-kynurenine O-beta-glucoside in the human lens. J Biochem 1981;89:103-109.
    • (1981) J Biochem , vol.89 , pp. 103-109
    • Bando, M.1    Nakajima, A.2    Satoh, K.3
  • 110
    • 0027453250 scopus 로고
    • UV filters in human lenses: Tryptophan catabolism
    • Wood AM, Truscott RJW: UV filters in human lenses: Tryptophan catabolism. Exp Eye Res 1993;56:317-325.
    • (1993) Exp Eye Res , vol.56 , pp. 317-325
    • Wood, A.M.1    Truscott, R.J.W.2
  • 111
    • 0028331969 scopus 로고
    • Ultraviolet filter compounds in human lenses: 3-yhdroxykynurenine glucoside formation
    • Wood AM, Truscott RJW: Ultraviolet filter compounds in human lenses: 3-yhdroxykynurenine glucoside formation. Vision Res 1994;34:1369-1374.
    • (1994) Vision Res , vol.34 , pp. 1369-1374
    • Wood, A.M.1    Truscott, R.J.W.2
  • 112
    • 0029858226 scopus 로고    scopus 로고
    • 3-Hydroxykynurenine transamination leads to the formation of the fluorescent substances in human lenses
    • Malina HZ, Martin XD: 3-Hydroxykynurenine transamination leads to the formation of the fluorescent substances in human lenses. Eur J Ophthalmol 1996;6:250-256.
    • (1996) Eur J Ophthalmol , vol.6 , pp. 250-256
    • Malina, H.Z.1    Martin, X.D.2
  • 113
    • 0023836582 scopus 로고
    • Age and the transmittance of the human crystalline lens
    • Weale RA: Age and the transmittance of the human crystalline lens. J Physiol 1988;395: 577-587.
    • (1988) J Physiol , vol.395 , pp. 577-587
    • Weale, R.A.1
  • 114
    • 0000473136 scopus 로고
    • The variation with age of the spectral transmissivity of the living human crystalline lens
    • Said FS, Weale RA: The variation with age of the spectral transmissivity of the living human crystalline lens. Gerontologia 1959;3: 213-231.
    • (1959) Gerontologia , vol.3 , pp. 213-231
    • Said, F.S.1    Weale, R.A.2
  • 115
    • 0021276774 scopus 로고
    • A new method of measuring in vivo the lens transmittance, and study of lens scatter, fluorescence and transmittance
    • Zeimer RC, Noth RM: A new method of measuring in vivo the lens transmittance, and study of lens scatter, fluorescence and transmittance. Ophthalmic Res 1984;16:246-255.
    • (1984) Ophthalmic Res , vol.16 , pp. 246-255
    • Zeimer, R.C.1    Noth, R.M.2
  • 116
    • 0021795781 scopus 로고
    • Lens transmission of blue-green light in diabetic patients as measured by autofluorophotometry
    • van Best JA, Vrij L, Oosterhuis JA: Lens transmission of blue-green light in diabetic patients as measured by autofluorophotometry. Invest Ophthalmol Vis Sci 1985;26:532-536.
    • (1985) Invest Ophthalmol Vis Sci , vol.26 , pp. 532-536
    • Van Best, J.A.1    Vrij, L.2    Oosterhuis, J.A.3
  • 117
    • 0025410113 scopus 로고
    • Time resolved spectroscopic studies on the intact human lens
    • Dillon J, Atherton ST: Time resolved spectroscopic studies on the intact human lens. Photochem Photobiol 1990;51:465-468.
    • (1990) Photochem Photobiol , vol.51 , pp. 465-468
    • Dillon, J.1    Atherton, S.T.2
  • 118
    • 0023243042 scopus 로고
    • Yellowing of the human lens: Nuclear and cortical contributions
    • Mellerio J: Yellowing of the human lens: Nuclear and cortical contributions. Vision Res 1987;27:1581-1587.
    • (1987) Vision Res , vol.27 , pp. 1581-1587
    • Mellerio, J.1
  • 119
    • 0025894762 scopus 로고
    • The lenticular nucleus, light and the retina
    • Weale RA: The lenticular nucleus, light and the retina. Exp Eye Res 1991;53:213-218.
    • (1991) Exp Eye Res , vol.53 , pp. 213-218
    • Weale, R.A.1
  • 120
    • 0001494321 scopus 로고
    • The glucoside of 3-hydroxykynurenine and other fluorescent compounds in the human lens
    • Elliott K, Fitzsimmons DW (eds): Amsterdam, Elsevier
    • van Heyningen R: The glucoside of 3-hydroxykynurenine and other fluorescent compounds in the human lens; in Elliott K, Fitzsimmons DW (eds): The Human Lens - in Relation to Cataract. Amsterdam, Elsevier, 1973.
    • (1973) The Human Lens - In Relation to Cataract
    • Van Heyningen, R.1
  • 121
    • 0015371022 scopus 로고
    • Age related changes in the structural proteins of the human lens
    • Satoh K: Age related changes in the structural proteins of the human lens. Exp Eye Res 1972;14:53-57.
    • (1972) Exp Eye Res , vol.14 , pp. 53-57
    • Satoh, K.1
  • 122
    • 0017190782 scopus 로고
    • Variations in fluorescence characteristics of intact human crystalline lens segments as a function of age
    • Jacobs R, Krohn DL: Variations in fluorescence characteristics of intact human crystalline lens segments as a function of age. J Gerontol 1976;31:641.
    • (1976) J Gerontol , vol.31 , pp. 641
    • Jacobs, R.1    Krohn, D.L.2
  • 124
    • 0022296716 scopus 로고
    • Calcium-induced lens protein aggregation accelerated by reactive oxygen species photosensitized in the presence of hydroxykynurenines
    • Bando M, Mikuni I, Obazawa H: Calcium-induced lens protein aggregation accelerated by reactive oxygen species photosensitized in the presence of hydroxykynurenines. Exp Eye Res 1985;40:813-818.
    • (1985) Exp Eye Res , vol.40 , pp. 813-818
    • Bando, M.1    Mikuni, I.2    Obazawa, H.3
  • 125
    • 0027297225 scopus 로고
    • The modification of proteins by 3-hydroxykynurenine
    • Stutchbury GM, Truscott RJW: The modification of proteins by 3-hydroxykynurenine. Exp Eye Res 1993;57:149-155.
    • (1993) Exp Eye Res , vol.57 , pp. 149-155
    • Stutchbury, G.M.1    Truscott, R.J.W.2
  • 126
    • 0028411472 scopus 로고
    • Model studies on the photochemical production of lenticular fluorophores
    • Ellozy AR, Wang RH, Dillon J: Model studies on the photochemical production of lenticular fluorophores. Photochem Photobiol 1994; 59:479-484.
    • (1994) Photochem Photobiol , vol.59 , pp. 479-484
    • Ellozy, A.R.1    Wang, R.H.2    Dillon, J.3
  • 127
    • 0025301584 scopus 로고
    • Morphology of the aging human lens. II. Ultrastructure of clear lens
    • Vrensen G, Kappelhof J, Willekens B: Morphology of the aging human lens. II. Ultrastructure of clear lens. Lens Eye Toxic Res 1990;7:1-30.
    • (1990) Lens Eye Toxic Res , vol.7 , pp. 1-30
    • Vrensen, G.1    Kappelhof, J.2    Willekens, B.3
  • 128
    • 0002878137 scopus 로고
    • Lens structure and forms of cataract
    • Duncan G (ed): EURAGE Publications, Netherlands
    • Bron AJ, Brown NAP: Lens structure and forms of cataract; in Duncan G (ed): The Lens: Transparency and Cataract. EURAGE Publications, Netherlands, 3-11, 1986.
    • (1986) The Lens: Transparency and Cataract , pp. 3-11
    • Bron, A.J.1    Brown, N.A.P.2


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