Adiponectin and resistin serum levels in women with polycystic ovary syndrome during oral glucose tolerance test: A significant reciprocal correlation between adiponectin and resistin independent of insulin resistance indices

Molecular Genetics and Metabolism

Volumn 85, Issue 1, 2005, Pages 61-69

  Lewandowski, Krzysztof C ^a,c   Szosland, Konrad ^b   O'Callaghan, Chris ^c,d   Tan, Bee K ^c   Randeva, Harpal S ^c   Lewinski, Andrzej ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b POLISH MOTHER S MEMORIAL HOSPITAL RESEARCH INSTITUTE   (Poland)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d QUEEN S UNIVERSITY   (Canada)

Author keywords

Adiponectin; Insulin resistance; Oral glucose tolerance test; Polycystic ovary syndrome; Resistin

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; GLUCOSE; HORMONE; INSULIN; LIPID; RESISTIN;

ADULT; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEMOCONCENTRATION; HOMEOSTASIS; HUMAN; HYPERINSULINEMIA; INFLAMMATION; INSULIN RESISTANCE; MEDICAL PARAMETERS; METABOLISM; ORAL GLUCOSE TOLERANCE TEST; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; RISK FACTOR;

ADENOVIRIDAE;

EID: 18044370063     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2004.12.014     Document Type: Article

References (66)

1. P. Arner The adipocyte in insulin resistance: Key molecules and the impact of thiazolidinediones Trends Endocrinol. Metab. 14 2003 137 145
2. Y. Arita, S. Kihara, N. Ouchi, M. Takahashi, K. Maeda, J. Miyagawa, K. Hotta, I. Shimomura, T. Nakamura, K. Miyaoka, H. Kuriyama, M. Nishida, S. Yamashita, K. Okubo, K. Matsubara, M. Muraguchi, Y. Ohmoto, T. Funahashi, and Y. Matsuzawa Paradoxical decrease of an adipose-specific protein adiponectin in obesity Biochem. Biophys. Res. Commun. 257 1999 79 83
3. C. Weyer, T. Funahashi, S. Tanaka, K. Hotta, Y. Matsuzawa, R.E. Pratley, and P.A. Tataranni Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hypoinsulinemia J. Clin. Endocrinol. Metab. 86 2001 1930 1935
4. P.J. Havel Control of energy homeostasis and insulin action by adipocyte hormones: Leptin, acylation stimulating protein, and adiponectin Curr. Opin. Lipidol. 13 2002 51 59
5. A.H. Berg, T.P. Combs, and P.E. Scherer ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism Trends Endocrinol. Metab. 13 2002 84 89
6. Y. Okamoto, S. Kihara, N. Ouchi, M. Nishida, Y. Arita, M. Kumada, K. Ohashi, N. Sakai, I. Shimomura, H. Kobayashi, N. Terasaka, T. Inaba, T. Funahashi, and Y. Matsuzawa Adiponectin reduces atherosclerosis in apolipoprotein E-deficient mice Circulation 106 2002 2767 2770
7. N. Ouchi, S. Kihara, T. Funahashi, T. Nakamura, M. Nishida, M. Kumada, Y. Okamoto, K. Ohashi, H. Nagaretani, K. Kishida, H. Nishizawa, N. Maeda, H. Kobayashi, H. Hiraoka, and Y. Matsuzawa Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue Circulation 100 2003 2473 2476
8. C.M. Steppan, S.T. Bailey, S. Bhat, E.J. Brown, R.R. Banerjee, C.M. Wright, H.R. Patel, R.S. Ahima, and M.A. Lazar The hormone resistin links obesity to diabetes Nature 409 2001 307 312
9. L. Patel, A.C. Buckels, I.J. Kinghorn, P.R. Murdock, J.D. Holbrook, C. Plumpton, C.H. Macphee, and S.A. Smith Resistin is expressed in human macrophages and directly regulated by PPARγ activators Biochem. Biophys. Res. Commun. 300 2003 472 476
10. M.W. Rajala, S. Obici, P.E. Scherer, and L. Rosetti Adipose-derived resistin and gut-derived resistin-like molecule-β selectively impair insulin action on glucose production J. Clin. Invest. 11 2003 225 230
11. M. Maebuchi, M. Machidori, R. Urade, T. Ogawa, and T. Moriyama Low resistin levels in adipose tissues and serum in high-fat fed mice and genetically obese mice: Development of an ELISA system for quantification of resistin Arch. Biochem. Biophys. 416 2003 164 170
12. P.G. McTernan, C.L. McTernan, R. Chetty, K. Jenner, F.M. Fisher, M.N. Laurer, J. Crocker, A.H. Barnett, and S. Kumar Increased resistin gene expression and protein expression in human abdominal adipose tissue J. Clin. Endocrinol. Metab. 87 2002 2407 2410
13. A. Dunaif Insulin resistance and the polycystic ovary syndrome: Mechanisms and implications for pathogenesis Endocr. Rev. 18 1997 774 800
14. G.S. Conway, R. Agrawall, D.J. Betteridge, and H.S. Jacobs Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome Clin. Endocrinol. (Oxf) 37 1992 119 126
15. D.S. Guzick Cardiovascular risk in women with polycystic ovarian syndrome Semin. Reprod. Endocrinol. 14 1996 45 49
16. M. Rajkhowa, J. Bichnell, M. Jones, and R.N. Clayton Insulin sensitivity in women with polycystic ovary syndrome: Relationship to hyperandrogenemia Fertil. Steril. 61 1994 605 612
17. R.A. Wild, R.D. Painter, P.B. Coulson, K.B. Carruth, and R.B. Ranney Lipoprotein lipid concentrations as cardiovascular risk in patients with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 61 1985 946 950
18. E. Dahlgren, S. Johansson, G. Lindstedt, F. Knutsson, A. Oden, P.O. Janson, L.A. Mattson, N. Crona, and P.A. Lundberg Women with polycystic ovary syndrome wedge resected in 1956 to 1965: A long term follow up focusing on natural history and circulating hormones Fertil. Steril. 57 1992 505 513
19. S. Zimmermann, R.A. Phillips, A. Dunaif, D.T. Finegood, C. Wilkenfeld, M. Ardeljan, R. Gorlin, and L.R. Krakoff Polycystic ovary syndrome: Lack of hypertension despite profound insulin resistance J. Clin. Endocrinol. Metab. 75 1992 508 513
20. T. Pierpoint, P.M. McKeigue, A.J. Isaacs, S.H. Wild, and H.S. Jacobs Mortality of women with polycystic ovary syndrome at long-term follow-up J. Clin. Epidemiol. 51 1998 581 586
21. D. Panidis, A. Kourtis, D. Farmakiotis, T. Mouslech, D. Rousso, and G. Koliakos Serum adiponectin levels in women with polycystic ovary syndrome Hum. Reprod. 18 2003 1790 1796
22. F. Orio Jr, S. Palomba, T. Cascella, G. Milan, R. Mioni, C. Pagano, F. Zullo, A. Colao, G. Lombardi, and R. Vettor Adiponectin levels in women with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 88 2003 2619 2623
23. D. Panidis, G. Koliakos, A. Koutis, D. Farmakiotis, T. Mouslech, and D. Rousso Serum resistin levels in women with polycystic ovary syndrome Fertil Steril. 81 2004 361 366
24. K.M. Seow, C.C. Juan, L.Y. Wu, Y.P. Hsu, W.M. Yang, Y.L. Tsai, J.L. Hwang, and L.T. Ho Serum and adipocyte resistin in polycystic ovary syndrome with insulin resistance Hum. Reprod. 19 2004 48 53
25. K.G. Alberti, and P.Z. Zimmet Definition, diagnosis, and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation Diabet. Med. 15 1998 539 553
26. R.S. Legro, D. Finegood, and A. Dunaif A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 83 1998 2694 2698
27. T.M. Wallace, and D.R. Matthew The assessment of insulin resistance in man Diabet. Med. 19 2002 527 534
28. M.F. Saad, G.M. Steil, W.W. Kades, M.F. Ayad, W.A. Elsewafy, R. Boyadjian, and S.D. Jinaquoda Differences between the tolbutamide-boosted and the insulin-modified minimal model protocols Diabetes 46 1997 1167 1171
29. D.R. Matthews, J.P. Hosker, A.S. Rudensky, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
30. K.J. Mather, A.E. Hunt, H.O. Steinberg, G. Paradisi, G. Hook, A. Katz, M.J. Quon, and A.D. Baron Repeatability characteristics of simple indices of insulin resistance: Implications for research applications J. Clin. Endocrinol. Metab. 86 2001 5457 5464
31. F. Abbasi, and G.M. Reaven Evaluation of the quantitative insulin sensitivity check index as an estimate of insulin sensitivity in humans Metabolism 51 2002 235 237
32. A. Katz, S. Nambi, K. Mather, A.D. Baron, D.A. Follmann, G. Sullivan, and M.J. Quon Quantitative insulin sensitivity check index: A simple, accurate method for assessing insulin sensitivity in humans J. Clin. Endocrinol. Metab. 85 2000 2402 2410
33. M. Matsuda, and R. DeFronzo Insulin sensitivity indices obtained from oral glucose tolerance testing Diabetes Care 9 1999 1462 1470
34. D. Panidis, A. Kourtis, A. Kukuvitis, D. Farmakiotis, N. Xita, I. Georgiou, and A. Tsatsoulis Association of the T45G polymorphism in exon 2 of the adiponectin gene with polycystic ovary syndrome: Role of Delta4 androstendione Hum. Reprod. 19 2004 1728 1733
35. L. Ibanez, and F. Zegher Ethynilestradiol-Drosperidone, Flutamide-Metformin, or both for adolescents and women with hyperinsulinaemic hyperadrogenism: Opposite effects on adipocytokines and body adiposity J. Clin. Endocrinol. Metab. 89 2004 1592 1597
36. P.H. Ducluzeau, P. Cousin, E. Malvoisin, H. Bornet, H. Vidal, M. Laville, and M. Pugeat Glucose-to-insulin ratio rather than sex hormone-binding globulin and adiponectin levels is the best predictor of insulin resistance in nonobese women with polycystic ovary syndrome J. Clin. Endocrinol. Metab. 88 2003 3626 3631
37. A.J. Morales, G.A. Laughlin, T. Butzow, H. Maheshwari, G. Baumann, and S.S. Yes Insulin, somatotropic and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: Common and distinct features J. Clin. Endocrinol. Metab. 81 1996 2854 2864
38. A.H. Balen, G.S. Conway, G. Kaltsas, K. Techatrasak, P.J. Manning, C. West, and H.S. Jacobs Polycystic ovary syndrome: The spectrum of disorder in 1741 patients Hum. Reprod. 10 1995 2107 2111
39. No authors stated, Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum. Reprod. 19 (2004) 41-47
40. G. Arnaldi, A. Angeli, A.B. Atkinson, X. Bertagna, F. Cavagnini, G.P. Chrousos, G.A. Fava, J.W. Findling, R.C. Gaillard, A.B. Grossman, B. Kola, A. Lacroix, T. Mancini, F. Mantero, J. Newell-Price, L.K. Nieman, N. Sonino, M.L. Vance, A. Giustina, and M. Boscaro Diagnosis and complications of Cushing's syndrome: A consensus statement J. Clin. Endocrinolol. Metab. 88 2003 5593 5602
41. F. Belfiore, S. Iannello, and G. Volpicelli Insulin sensitivity indices calculated from basal and OGTT-induced insulin, glucose, and FFA levels Mol. Genet. Metab. 63 1998 134 141
42. F. Belfiore, and S. Iannello Insulin resistance in obesity: Metabolic mechanisms and measurement methods Mol. Genet. Metab. 65 1998 121 128
43. N. Ouchi, S. Kihara, Y. Arita, K. Maeda, H. Kuriyama, Y. Okamoto, K. Hotta, M. Nishida, M. Takahashi, T. Nakamura, S. Yamashita, T. Funahashi, and Y. Matsuzawa Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin Circulation 100 1999 2473 2476
44. J.M. Way, C.Z. Gorgun, Q. Tong, K.T. Uysal, K.K. Brown, W.W. Harrington, W.R. Oliver Jr, T.M. Willson, S.A. Kliewer, and G.S. Hotamisligil Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists J. Biol. Chem. 276 2001 25651 25653
45. P.J. English, S.R. Coughlin, K. Hayden, I.A. Malik, and J.P. Wilding Plasma adiponectin increases postprandially in obese, but not in lean subjects Obes. Res. 11 2003 839 844
46. P.W. Peake, A.D. Kriketos, G.S. Denyer, L.V. Campbell, and J.A. Charlesworth The postprandial response of adiponectin to a high-fat meal in normal and insulin resistant subjects Int. J. Obes. Relat. Metab. Disord. 27 2003 657 662
47. N. Ouchi, S. Kihara, T. Funahashi, Y. Matsuzawa, and K. Walsh Obesity, adiponectin and vascular inflammatory disease Curr. Opin. Lipidol. 14 2003 561 566
48. S. Engeli, M. Feldpausch, K. Gorzelniak, F. Hartwig, U. Heintze, J. Janke, M. Mohlig, A.F. Pfeiffer, F.C. Luft, and A.M. Sharma Association between adiponectin and mediators of inflammation in obese women Diabetes 52 2003 942 947
49. K.C. Tan, A. Xu, W.S. Chow, M.C. Lam, V.H. Ai, S.C. Tam, and K.S. Lam Hypoadiponectinemia is associated with impaired endothelium-dependent vasodilatation J. Clin. Endocrinol. Metab. 89 2004 765 769
50. X.T. Tigno, I.K. Selaru, S.V. Angeloni, and B.C. Hansen Is microvascular flow rate related to ghrelin, leptin and adiponectin levels? Clin. Hemorheol. Microcirc. 29 2003 409 416
51. H. Chen, M. Montagnani, T. Funahashi, I. Shimomura, and M.J. Quon Adiponectin stimulates production of nitric oxide in vascular endothelial cells J. Biol. Chem. 278 2003 45021 45026
52. S. Verma, S.H. Li, C.H. Wang, P.W. Fedak, R.K. Li, R.D. Weisel, and D.A. Mickle Resistin promotes endothelial cell activation: Further evidence of adipokine-endothelial interaction Circulation 108 2003 736 740
53. M. Lehrke, M.P. Reilly, S.C. Millington, N. Iqbal, D.J. Rader, and M.A. Lazar An inflammatory cascade leading to hyperresistinemia in humans PLoS Med. 1 2004 161 168
54. D. Kawanami, K. Maemura, N. Takeda, T. Harada, T. Nojiri, Y. Imai, I. Manabe, K. Utsunomiya, and R. Nagai Direct reciprocal effects of resistin and adiponectin: A new insight into adipocytokine-endothelial cell interactions Biochem. Biophys. Res. Commun. 314 2004 415 419
55. E.O. Talbott, D.S. Guzick, K. Sutton-Tyrrell, K.P. McHugh-Pemu, J.V. Zborowski, K.E. Remsberg, and L.H. Kuller Evidence for association between polycystic ovary syndrome and premature carotid atherosclerosis in middle-aged women Arterioscler. Thromb. Vasc. Biol. 20 2000 2414 2421
56. F. Orio, S. Palomba, L. Spinelli, T. Cascella, L. Tauchmanova, F. Zullo, G. Lombardi, and A. Colao The cardiovascular risk of young women with polycystic ovary syndrome: An observational analytical, prospective case control study J. Clin. Endocrinol. Metab. 89 2004 3696 3701
57. S.J. Hong, C.G. Park, H.S. Seo, D.J. Oh, and Y.M. Ro Associations among plasma adiponectin, hypertension, left ventricular diastolic function and left ventricular mass index Blood Press. 13 2004 236 242
58. M.J. Quon Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity J. Clin. Endocrinol. Metab. 85 2001 4615 4617
59. J.V. Silha, M. Krsek, J.V. Skrha, P. Sucharda, B.L. Nyomba, and L.J. Murphy Plasma resistin, adiponectin and leptin levels in lean and obese subjects: Correlations with insulin resistance Eur. J. Endocrinol. 149 2003 331 335
60. J.V. Silha, M. Krsek, V. Hana, J. Marek, J. Jezkova, V. Weiss, and L.J. Murphy Perturbations in adiponectin, leptin and resistin levels in acromegaly: Lack of correlation with insulin resistance Clin. Endocrinol. (Oxf) 58 2003 736 742
61. L.U. Monzillo, O. Hamdy, E.S. Horton, S. Ledbury, C. Mullooly, C. Jarema, S. Porter, K. Ovalle, A. Moussa, and C.S. Mantzoros Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance Obes. Res. 11 2003 1048 1054
62. O. Tschritter, A. Fritsche, C. Thamer, M. Haap, F. Shirkavand, S. Rahe, H. Staiger, E. Maerker, H. Haring, and M. Stumvoll Plasma adiponectin concentrations predict insulin sensitivity both glucose and lipid metabolism Diabetes 52 2003 239 243
63. J. Spranger, M. Möhlig, U. Wegewitz, M. Ristow, A.F.H. Pfeiffer, T. Schill, H.W. Schlosser, G. Brabant, and C. Scholf Adiponectin is independently associated with insulin sensitivity in women with polycystic ovary syndrome Clin. Endocrinol. (Oxf) 61 2004 738 746
64. U.B. Pajvani, M. Hawkins, T.P. Combs, M.W. Rajala, T. Doebber, J.P. Berger, J.A. Wagner, M. Wu, A. Knopps, A.H. Xiang, K.M. Utzschneider, S.E. Kahn, J.M. Olefsky, T.A. Buchanan, and P.E. Scherer Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity J. Biol. Chem. 279 2004 12152 12162
65. B.S. Youn, K.Y. Yu, H.J. Park, N.S. Lee, S.S. Min, M.Y. Youn, Y.M. Cho, Y.J. Park, S.Y. Kim, H.K. Lee, and K.S. Park Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes J. Clin. Endocrinol. Metab. 89 2004 150 156
66. L.K. Heilbronn, J. Rood, L. Janderova, J.B. Albu, D.E. Kelley, E. Ravussin, and S.R. Smith Relationship between serum resistin concentrations and insulin resistance in nonobese, obese and obese diabetic subjects J. Clin. Endocrinol. Metab. 89 2004 1844 1848