메뉴 건너뛰기




Volumn 81, Issue 8, 1996, Pages 2854-2864

Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: Common and distinct features

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; FOLLITROPIN; GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RELEASING FACTOR; HYDROXYPROGESTERONE; INSULIN; LUTEINIZING HORMONE; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; TESTOSTERONE;

EID: 0029833087     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.8.2854     Document Type: Article
Times cited : (398)

References (70)
  • 1
    • 0026745038 scopus 로고
    • Intraovarian regulation peptidergic signaling systems
    • Adashi EY, and Rohan M. 1992 Intraovarian regulation peptidergic signaling systems. Trends Endocrinol Metab. 3:243 - 248.
    • (1992) Trends Endocrinol Metab , vol.3 , pp. 243-248
    • Adashi, E.Y.1    Rohan, M.2
  • 2
    • 0028898460 scopus 로고
    • The insulin-like growth factor system in normal and abnormal human ovarian follicle development
    • Giudice LC. 1995 The insulin-like growth factor system in normal and abnormal human ovarian follicle development. Am J Med. 98:48S - 54S.
    • (1995) Am J Med , vol.98
    • Giudice, L.C.1
  • 3
    • 0027169091 scopus 로고
    • Interface between extra- and intraovarian factors in polycystic ovarian syndrome
    • Yen SSC, Laughlin GA, Morales AJ. 1993 Interface between extra- and intraovarian factors in polycystic ovarian syndrome. Proc NY Acad Sci. 687:98.
    • (1993) Proc NY Acad Sci , vol.687 , pp. 98
    • Yen, S.S.C.1    Laughlin, G.A.2    Morales, A.J.3
  • 4
    • 0023713274 scopus 로고
    • The role of hyperinsulinemia in the pathogenesis of ovarian hyperandrogenism
    • Barbieri RL, Smith S, Ryan KJ. 1988 The role of hyperinsulinemia in the pathogenesis of ovarian hyperandrogenism. Fertil Steril. 50:197 - 203.
    • (1988) Fertil Steril , vol.50 , pp. 197-203
    • Barbieri, R.L.1    Smith, S.2    Ryan, K.J.3
  • 5
    • 0025601897 scopus 로고
    • Insulin infusion acutely augments ovarian androgen production in normal women
    • Stuart CA, Nagamani M. 1990 Insulin infusion acutely augments ovarian androgen production in normal women. Fertil Steril. 54:788 - 792.
    • (1990) Fertil Steril , vol.54 , pp. 788-792
    • Stuart, C.A.1    Nagamani, M.2
  • 6
    • 0023269432 scopus 로고
    • Hyperinsulinemia and hyperandrogenism: In vivo androgen response to insulin infusion
    • Stuart CA, Prince MJ, Peters EJ, et al. 1987 Hyperinsulinemia and hyperandrogenism: in vivo androgen response to insulin infusion. Obstet Gynecol. 69:921 - 925.
    • (1987) Obstet Gynecol , vol.69 , pp. 921-925
    • Stuart, C.A.1    Prince, M.J.2    Peters, E.J.3
  • 7
    • 0027214646 scopus 로고
    • The impact of obesity on hyperandrogenism and polycystic ovary syndrome in premenopausal women
    • Oxf
    • Pasquali R, Casimirri F. 1993 The impact of obesity on hyperandrogenism and polycystic ovary syndrome in premenopausal women. Clin Endocrinol (Oxf). 39:1 - 16.
    • (1993) Clin Endocrinol , vol.39 , pp. 1-16
    • Pasquali, R.1    Casimirri, F.2
  • 8
    • 0024355532 scopus 로고
    • The central role of obesity (hyperinsulinemia) in the pathogenesis of the polycystic ovary syndrome
    • Nestler JE, Clore JN, and Blackard WG. 1989 The central role of obesity (hyperinsulinemia) in the pathogenesis of the polycystic ovary syndrome. Am J Obstet Gynecol. 161:1095.
    • (1989) Am J Obstet Gynecol , vol.161 , pp. 1095
    • Nestler, J.E.1    Clore, J.N.2    Blackard, W.G.3
  • 9
    • 0027255158 scopus 로고
    • In vivo and in vitro effects of growth hormone on estradiol secretion by human granulosa cells
    • Barreca A, Artini PG, DelMonte P, et al. 1993 In vivo and in vitro effects of growth hormone on estradiol secretion by human granulosa cells. J Clin Endocrinol Metab. 77:61 - 67.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 61-67
    • Barreca, A.1    Artini, P.G.2    DelMonte, P.3
  • 10
    • 0024994950 scopus 로고
    • Direct gonadotrophic effect of growth hormone on oestradiol production by human granulosa cells in vitro
    • Mason HD, Martikainen H, Beard RW, Anyaoku V, Franks S. 1990 Direct gonadotrophic effect of growth hormone on oestradiol production by human granulosa cells in vitro. J Endocrinol 126:R1 - R4.
    • (1990) J Endocrinol , vol.126
    • Mason, H.D.1    Martikainen, H.2    Beard, R.W.3    Anyaoku, V.4    Franks, S.5
  • 11
    • 0027395564 scopus 로고
    • The potential of growth hormone to female reproductive physiology and pathophysiology
    • Katz E, Ricciarelli E, Adashi E. 1993 The potential of growth hormone to female reproductive physiology and pathophysiology. Fertil Steril. 59:8 - 34.
    • (1993) Fertil Steril , vol.59 , pp. 8-34
    • Katz, E.1    Ricciarelli, E.2    Adashi, E.3
  • 12
    • 0028040909 scopus 로고
    • Identification and cellular localization of growth hormone receptor gene expression in the human ovary
    • Sharara FI, Nieman LK. 1994 Identification and cellular localization of growth hormone receptor gene expression in the human ovary. J Clin Endocrinol Metab. 79:670 - 672.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 670-672
    • Sharara, F.I.1    Nieman, L.K.2
  • 13
    • 0027423255 scopus 로고
    • Expression of the insulin-like growth factor (IGF)-I and IGF-II and the IGF-I, IGF-II and insulin receptor genes and localization of the gene products in the human ovary
    • El-Roeiy A, Chen X, Roberts VJ, LeRoith D, Roberts CT, Yen SSC. 1993 Expression of the insulin-like growth factor (IGF)-I and IGF-II and the IGF-I, IGF-II and insulin receptor genes and localization of the gene products in the human ovary. J Clin Endocrinol Metab. 77:1411 - 1418.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1411-1418
    • El-Roeiy, A.1    Chen, X.2    Roberts, V.J.3    Leroith, D.4    Roberts, C.T.5    Yen, S.S.C.6
  • 14
    • 0027475437 scopus 로고
    • Anatomy of the human ovarian insulin-like growth factor system
    • Zhou J, and Bondy C. 1993 Anatomy of the human ovarian insulin-like growth factor system. Biol Reprod. 48:467 - 482.
    • (1993) Biol Reprod , vol.48 , pp. 467-482
    • Zhou, J.1    Bondy, C.2
  • 15
    • 0028279242 scopus 로고
    • Expression of the gene encoding the insulin-like growth factors (IGF-I and IGF-II), the IGF and insulin receptors and IGF binding proteins (IGFBPs 1-6), and the localization of their gene products in normal and polycystic ovary syndrome ovaries
    • El-Roeiy A, Roberts VJ, Shimasaki S, et al. 1994 Expression of the gene encoding the insulin-like growth factors (IGF-I and IGF-II), the IGF and insulin receptors and IGF binding proteins (IGFBPs 1-6), and the localization of their gene products in normal and polycystic ovary syndrome ovaries. J Clin Endocrinol Metab. 78:1488 - 1496.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1488-1496
    • El-Roeiy, A.1    Roberts, V.J.2    Shimasaki, S.3
  • 16
    • 0018840897 scopus 로고
    • The polycystic ovary syndrome
    • Oxf
    • Yen SSC. 1980 The polycystic ovary syndrome. Clin Endocrinol (Oxf). 12:177.
    • (1980) Clin Endocrinol , vol.12 , pp. 177
    • Yen, S.S.C.1
  • 17
    • 0024361382 scopus 로고
    • Polycystic ovary syndrome: A changing perspective
    • Oxf
    • Franks S. 1989 Polycystic ovary syndrome: a changing perspective. Clin Endocrinol (Oxf). 31:87 - 120.
    • (1989) Clin Endocrinol , vol.31 , pp. 87-120
    • Franks, S.1
  • 19
    • 0027212609 scopus 로고
    • Roles of LH and insulin resistance in lean and obese polycystic ovary syndrome
    • Oxf
    • Grulet H, Hecart AC, Delemer B, et al. 1993 Roles of LH and insulin resistance in lean and obese polycystic ovary syndrome. Clin Endocrinol (Oxf). 38:621 - 626.
    • (1993) Clin Endocrinol , vol.38 , pp. 621-626
    • Grulet, H.1    Hecart, A.C.2    Delemer, B.3
  • 20
    • 0028037635 scopus 로고
    • The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women
    • Oxf
    • Holte J, Bergh T, Gennarelli G, Wide L. 1994 The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women. Clin Endocrinol (Oxf). 41:473 - 481.
    • (1994) Clin Endocrinol , vol.41 , pp. 473-481
    • Holte, J.1    Bergh, T.2    Gennarelli, G.3    Wide, L.4
  • 22
    • 0026781569 scopus 로고
    • Body weight, hyperinsulinemia, and gonadotropin levels in the polycystic ovarian syndrome: Evidence of two distinct populations
    • Dale PO, Tanbo T, Vaaler S, Abyholm T. 1992 Body weight, hyperinsulinemia, and gonadotropin levels in the polycystic ovarian syndrome: evidence of two distinct populations. Fertil Steril. 58:487 - 491.
    • (1992) Fertil Steril , vol.58 , pp. 487-491
    • Dale, P.O.1    Tanbo, T.2    Vaaler, S.3    Abyholm, T.4
  • 23
    • 0000189333 scopus 로고
    • Insulin resistance and yperandrogenism: Update 1995
    • Poretsky L. 1994 Insulin resistance and yperandrogenism: update 1995. Endoer Rev. 2:125 - 129.
    • (1994) Endoer Rev , vol.2 , pp. 125-129
    • Poretsky, L.1
  • 24
    • 0027201962 scopus 로고
    • Insulin hypersecretion together with high luteinizing hormone concentrations augments androgen secretion in oral glucose tolerance test in women with polycystic ovarian disease
    • Antilla L, Koskinen P, Jaatinen TA, et al. 1993 Insulin hypersecretion together with high luteinizing hormone concentrations augments androgen secretion in oral glucose tolerance test in women with polycystic ovarian disease. Hum Reprod. 8:1179 - 1183.
    • (1993) Hum Reprod , vol.8 , pp. 1179-1183
    • Antilla, L.1    Koskinen, P.2    Jaatinen, T.A.3
  • 25
    • 0024997304 scopus 로고
    • An abnormality of the growth hormone/insulin-like growth factor I axis in women with polycystic ovary syndrome
    • Kazer RR, Unterman TG, Glick RP. 1990 An abnormality of the growth hormone/insulin-like growth factor I axis in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 71:958 - 962.
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 958-962
    • Kazer, R.R.1    Unterman, T.G.2    Glick, R.P.3
  • 26
    • 0027049876 scopus 로고
    • Twenty-four hour serum growth hormone, insulin, C-peptide and blood glucose profiles and serum insulin-like growth factor-1 concentrations in women with polycystic ovaries
    • Prevelic GM, Wurzburger MI, Balint-Peric I, Ginsburg J. 1992 Twenty-four hour serum growth hormone, insulin, C-peptide and blood glucose profiles and serum insulin-like growth factor-1 concentrations in women with polycystic ovaries. Horm Res. 37:125 - 131.
    • (1992) Horm Res , vol.37 , pp. 125-131
    • Prevelic, G.M.1    Wurzburger, M.I.2    Balint-Peric, I.3    Ginsburg, J.4
  • 27
    • 0027979541 scopus 로고
    • Overnight secretion pattern of growth hormone, sex hormone binding globulin, insulin-like growth factor-I and its binding protein in obese and non-obese women with polycystic ovarian disease
    • Insler V, Barash A, Shohanm A, et al. 1994 Overnight secretion pattern of growth hormone, sex hormone binding globulin, insulin-like growth factor-I and its binding protein in obese and non-obese women with polycystic ovarian disease. Isr J Med Sci. 30:42 - 47.
    • (1994) Isr J Med Sci , vol.30 , pp. 42-47
    • Insler, V.1    Barash, A.2    Shohanm, A.3
  • 28
    • 0026689801 scopus 로고
    • An abnormality of the growth hormone/insulin-like growth factor-1 axis in women with polycystic ovary syndrome due to coexistent obesity
    • Slowinska-Srzednicka J, Zgliczynski W, Makowska A, et al. 1992 An abnormality of the growth hormone/insulin-like growth factor-1 axis in women with polycystic ovary syndrome due to coexistent obesity. J Clin Endocrinol Metab. 74:1432 - 1435.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1432-1435
    • Slowinska-Srzednicka, J.1    Zgliczynski, W.2    Makowska, A.3
  • 29
    • 0023879442 scopus 로고
    • Polycystic ovaries: A common finding in normal women
    • Poison DW, Wadsworth J, Adams J, Franks S. 1988 Polycystic ovaries: a common finding in normal women. Lancet. 1:870 - 872.
    • (1988) Lancet , vol.1 , pp. 870-872
    • Poison, D.W.1    Wadsworth, J.2    Adams, J.3    Franks, S.4
  • 30
    • 0027274710 scopus 로고
    • Ethnicity and polycystic ovary syndrome are associated with independent and additive decreases in insulin action in Caribbean-Hispanic women
    • Dunaif A, Sorbara L, Delson R, Green G. 1993 Ethnicity and polycystic ovary syndrome are associated with independent and additive decreases in insulin action in Caribbean-Hispanic women. Diabetes. 42:1462 - 1468.
    • (1993) Diabetes , vol.42 , pp. 1462-1468
    • Dunaif, A.1    Sorbara, L.2    Delson, R.3    Green, G.4
  • 31
    • 0028000126 scopus 로고
    • Ethnic differences in secretion, sensitivity and hepatic extraction of insulin in black and white Americans
    • Osei K, Schuster DP. 1994 Ethnic differences in secretion, sensitivity and hepatic extraction of insulin in black and white Americans. Diabetes Med. 11:755 - 762.
    • (1994) Diabetes Med , vol.11 , pp. 755-762
    • Osei, K.1    Schuster, D.P.2
  • 32
    • 0024515617 scopus 로고
    • Opioidergic regulation of LH pulsatility in women with polycystic ovary syndrome
    • Oxf
    • Berga SL, Yen SSC. 1989 Opioidergic regulation of LH pulsatility in women with polycystic ovary syndrome. Clin Endocrinol (Oxf). 30:177 - 84.
    • (1989) Clin Endocrinol , vol.30 , pp. 177-184
    • Berga, S.L.1    Yen, S.S.C.2
  • 33
    • 0027531568 scopus 로고
    • Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model
    • Steil GM, Volund A, Kahn SE, Bergman RN. 1993 Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Diabetes. 42:250 - 256.
    • (1993) Diabetes , vol.42 , pp. 250-256
    • Steil, G.M.1    Volund, A.2    Kahn, S.E.3    Bergman, R.N.4
  • 34
    • 0002128535 scopus 로고
    • The minimal modeling method. Assessment of insulin sensitivity and beta-cell function in vivo
    • Clarke WL, Larner J, Pohl SL, eds. New York: Wiley and Sons
    • Bergman RN, Beard JC, Chen M. 1986 The minimal modeling method. Assessment of insulin sensitivity and beta-cell function in vivo. In: Clarke WL, Larner J, Pohl SL, eds. Methods in diabetes research. New York: Wiley and Sons. 15 - 34.
    • (1986) Methods in Diabetes Research , pp. 15-34
    • Bergman, R.N.1    Beard, J.C.2    Chen, M.3
  • 36
    • 0024546530 scopus 로고
    • Alterations in the hypothalamic-pituitary-ovarian and the hypothalamic-pituitary-adrenal axes in athletic women
    • Loucks AB, Mortola JF, Girton L, Yen SSC. 1989 Alterations in the hypothalamic-pituitary-ovarian and the hypothalamic-pituitary-adrenal axes in athletic women. J Clin Endocrinol Metab. 68:402 - 411.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 402-411
    • Loucks, A.B.1    Mortola, J.F.2    Girton, L.3    Yen, S.S.C.4
  • 37
    • 0028927658 scopus 로고
    • Regulation of insulin-like growth factor binding protein-1 (IGFBP-1) during the 24h metabolic clock and in response to hypoinsulinemia induced by fasting and Sandostatin in normal women
    • Holden JP, Bützow TL, Laughlin GA, Ho M, Morales AJ, Yen SSC. 1995 Regulation of insulin-like growth factor binding protein-1 (IGFBP-1) during the 24h metabolic clock and in response to hypoinsulinemia induced by fasting and Sandostatin in normal women. J Soc Gynecol Invest. 2:38 - 44.
    • (1995) J Soc Gynecol Invest , vol.2 , pp. 38-44
    • Holden, J.P.1    Bützow, T.L.2    Laughlin, G.A.3    Ho, M.4    Morales, A.J.5    Yen, S.S.C.6
  • 38
    • 0017141668 scopus 로고
    • A simple method for assay of eight steroids in small volumes of plasma
    • Anderson DC, Hopper BR, Lasley BL, Yen SSC. 1976 A simple method for assay of eight steroids in small volumes of plasma. Steroids. 28:179 - 196.
    • (1976) Steroids , vol.28 , pp. 179-196
    • Anderson, D.C.1    Hopper, B.R.2    Lasley, B.L.3    Yen, S.S.C.4
  • 39
    • 0027412630 scopus 로고
    • Regulation of growth hormone binding protein in man: Comparison of gel chromotgraphy and immunoprecipitation methods
    • Ho KKY, Valiontis E, Waters MJ, Rajkovic IA. 1993 Regulation of growth hormone binding protein in man: comparison of gel chromotgraphy and immunoprecipitation methods. J Clin Endocrinol Metab. 76:302 - 308.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 302-308
    • Ho, K.K.Y.1    Valiontis, E.2    Waters, M.J.3    Rajkovic, I.A.4
  • 40
    • 0022447036 scopus 로고
    • Cluster analysis: A simple, versatile and robust algorithm for endocrine pulse detection
    • Veldhuis JD, Johnson ML. 1986 Cluster analysis: a simple, versatile and robust algorithm for endocrine pulse detection. Am J Physiol. 250:E486 - E490.
    • (1986) Am J Physiol , vol.250
    • Veldhuis, J.D.1    Johnson, M.L.2
  • 41
    • 0026699302 scopus 로고
    • Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome
    • Dunaif A, Segal KR, Shelley DR, et al. 1992 Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome. Diabetes. 41:1257 - 1266.
    • (1992) Diabetes , vol.41 , pp. 1257-1266
    • Dunaif, A.1    Segal, K.R.2    Shelley, D.R.3
  • 43
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W, Dobrjansky A. 1989 Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes. 38:1165.
    • (1989) Diabetes , vol.38 , pp. 1165
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 44
    • 0027278472 scopus 로고
    • Defects in beta-cell function in functional ovarian hyperandrogenism
    • O'Meara NM, Blackman JD, Ehrmann DA, et al. 1993 Defects in beta-cell function in functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 76:1241 - 1247.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1241-1247
    • O'Meara, N.M.1    Blackman, J.D.2    Ehrmann, D.A.3
  • 45
    • 0029880488 scopus 로고    scopus 로고
    • β-Cell dysfunction independent of obesity and glucose intolerance in the polycystic ovary syndrome
    • Dunaif A, Finegood DT. 1996 β-Cell dysfunction independent of obesity and glucose intolerance in the polycystic ovary syndrome. J Clin Endocrinol Metab. 81:942 - 947.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 942-947
    • Dunaif, A.1    Finegood, D.T.2
  • 46
    • 0027131201 scopus 로고
    • Normal basal and insulinstimulated fuel metabolism in lean women with the polycystic ovary syndrome
    • Ovesen P, Moller J, Ingerslev HJ, et al. 1993 Normal basal and insulinstimulated fuel metabolism in lean women with the polycystic ovary syndrome. J Clin Endocrinol Metab. 77:1636 - 1640.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1636-1640
    • Ovesen, P.1    Moller, J.2    Ingerslev, H.J.3
  • 47
    • 0028345924 scopus 로고
    • Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance
    • Holte J, Bergh T, Berne C, Berglund L, Lithell J. 1994 Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance. J Clin Endocrinol Metab. 78:1052 - 1058.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1052-1058
    • Holte, J.1    Bergh, T.2    Berne, C.3    Berglund, L.4    Lithell, J.5
  • 49
    • 0021055647 scopus 로고
    • Insulin resistance in polycystic ovary syndrome
    • Shoupe D, Kumar DD, Lobo RA. 1983 Insulin resistance in polycystic ovary syndrome. Am J Obstet Gynecol. 147:588 - 592.
    • (1983) Am J Obstet Gynecol , vol.147 , pp. 588-592
    • Shoupe, D.1    Kumar, D.D.2    Lobo, R.A.3
  • 50
    • 0027411120 scopus 로고
    • Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin
    • Bergh C, Carlsson B, Olsson JH, et al. 1993 Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin. Fertil Steril. 59:323 - 331.
    • (1993) Fertil Steril , vol.59 , pp. 323-331
    • Bergh, C.1    Carlsson, B.2    Olsson, J.H.3
  • 51
    • 0028029753 scopus 로고
    • Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries
    • Gilling-Smith C, Wills DS, Mason HD, Franks S. 1994 Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries. J Clin Endocrinol Metab. 79:1158 - 1165.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 1158-1165
    • Gilling-Smith, C.1    Wills, D.S.2    Mason, H.D.3    Franks, S.4
  • 52
    • 0028921511 scopus 로고
    • Metabolic regulation of androgen production by human thecal cells in vitro
    • Nahum R, Thong KJ, Hillier SG. 1995 Metabolic regulation of androgen production by human thecal cells in vitro. Hum Reprod. 10:75 - 81.
    • (1995) Hum Reprod , vol.10 , pp. 75-81
    • Nahum, R.1    Thong, K.J.2    Hillier, S.G.3
  • 53
    • 0021337501 scopus 로고
    • Aromatase activity in human granulosa cells during follicular development and the modulation by follicle stimulating hormone and insulin
    • Garzo VG, Dorrington JH. 1984 Aromatase activity in human granulosa cells during follicular development and the modulation by follicle stimulating hormone and insulin. Am J Obstet Gynecol. 148:657 - 662.
    • (1984) Am J Obstet Gynecol , vol.148 , pp. 657-662
    • Garzo, V.G.1    Dorrington, J.H.2
  • 54
    • 0025341827 scopus 로고
    • The effects of insulin and insulin-like growth factors-1 and II on estradiol production by granulosa cells of polycystic ovaries
    • Erickson GF, Magoffin DA, Cragun JF, Chang RJ. 1990 The effects of insulin and insulin-like growth factors-1 and II on estradiol production by granulosa cells of polycystic ovaries. J Clin Endocrinol Metab. 70:894 - 902.
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 894-902
    • Erickson, G.F.1    Magoffin, D.A.2    Cragun, J.F.3    Chang, R.J.4
  • 55
    • 0018906734 scopus 로고
    • Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease
    • Burghen GA, Givens JR, Kitabchi AE. 1983 Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol Metab. 50:113.
    • (1983) J Clin Endocrinol Metab , vol.50 , pp. 113
    • Burghen, G.A.1    Givens, J.R.2    Kitabchi, A.E.3
  • 56
    • 10144233593 scopus 로고
    • Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome
    • Nestler JE, Barlascini CO, Matt DW, Steingold KA, et al. 1989 Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab. 72:83 - 89.
    • (1989) J Clin Endocrinol Metab , vol.72 , pp. 83-89
    • Nestler, J.E.1    Barlascini, C.O.2    Matt, D.W.3    Steingold, K.A.4
  • 57
    • 0026543775 scopus 로고
    • Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome
    • Oxf
    • Kiddy DS, Hamilton-Fairley D, Bush A, et al. 1992 Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf). 36:105 - 111.
    • (1992) Clin Endocrinol , vol.36 , pp. 105-111
    • Kiddy, D.S.1    Hamilton-Fairley, D.2    Bush, A.3
  • 58
    • 0029142760 scopus 로고
    • Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome
    • Holte J, Bergh R, Berne C, Wide L, Lithell J. 1995 Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome. J Clin Endocrinol Metab. 80:2586 - 2593.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2586-2593
    • Holte, J.1    Bergh, R.2    Berne, C.3    Wide, L.4    Lithell, J.5
  • 59
    • 0028356926 scopus 로고
    • Accelerated 24h LH pulsatile activity in adolescent girls with ovarian hyperandrogenism: Relevance to the developmental phase of polycystic ovarian syndrome
    • Apter D, Butzow T, Laughlin GA, Yen SSC. 1994 Accelerated 24h LH pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome. J Clin Endocrinol Metab. 79:119 - 125.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 119-125
    • Apter, D.1    Butzow, T.2    Laughlin, G.A.3    Yen, S.S.C.4
  • 60
    • 0028889654 scopus 로고
    • Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism
    • Apter D, Butzow T, Laughlin GA, Yen SSC. 1995 Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism. J Clin Endocrinol Metab. 80:2966 - 2973.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 2966-2973
    • Apter, D.1    Butzow, T.2    Laughlin, G.A.3    Yen, S.S.C.4
  • 61
    • 0028210928 scopus 로고
    • Growth hormone-binding proteins: State of the art
    • Baumann G. 1994 Growth hormone-binding proteins: state of the art. J Endocrinol. 141:1 - 6.
    • (1994) J Endocrinol , vol.141 , pp. 1-6
    • Baumann, G.1
  • 62
    • 0024531987 scopus 로고
    • Dose-response characteristics for supppression of low molecular weight plasma insulin-like growth factor-binding protein by insulin
    • Suikkari AM, Koivisto VA, Koistinen R, Seppala M, Yki-Jarvinen H. 1989 Dose-response characteristics for supppression of low molecular weight plasma insulin-like growth factor-binding protein by insulin. J Clin Endocrinol Metab. 68:135 - 140.
    • (1989) J Clin Endocrinol Metab , vol.68 , pp. 135-140
    • Suikkari, A.M.1    Koivisto, V.A.2    Koistinen, R.3    Seppala, M.4    Yki-Jarvinen, H.5
  • 64
    • 0014767566 scopus 로고
    • Inappropriate secretion of follicle-stimulating hormone and luteinizing hormone in polycystic ovarian disease
    • Yen SSC, Vela P, Rankin J. 1970 Inappropriate secretion of follicle-stimulating hormone and luteinizing hormone in polycystic ovarian disease. J Clin Endocrinol Metab. 30:435 - 442.
    • (1970) J Clin Endocrinol Metab , vol.30 , pp. 435-442
    • Yen, S.S.C.1    Vela, P.2    Rankin, J.3
  • 65
    • 0017068476 scopus 로고
    • Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome
    • Rebar R, Judd HL, Yen SSC, Rakoff J, VandenBerg G, Naftolin F. 1976 Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest. 57:1320 - 1329.
    • (1976) J Clin Invest , vol.57 , pp. 1320-1329
    • Rebar, R.1    Judd, H.L.2    Yen, S.S.C.3    Rakoff, J.4    VandenBerg, G.5    Naftolin, F.6
  • 66
    • 0022414079 scopus 로고
    • Pulsatile luteinizing hormone patterns in the follicular phase of the menstrual cycle, polycystic ovarian disease (PCOD) and non-PCOD secondary amenorrhea
    • Burger CW, Korsen T, van Kessel H, van Dop PA, Caron FJM, Schoemaker J. 1985 Pulsatile luteinizing hormone patterns in the follicular phase of the menstrual cycle, polycystic ovarian disease (PCOD) and non-PCOD secondary amenorrhea. J Clin Endocrinol Metab. 61:1126 - 1132.
    • (1985) J Clin Endocrinol Metab , vol.61 , pp. 1126-1132
    • Burger, C.W.1    Korsen, T.2    Van Kessel, H.3    Van Dop, P.A.4    Caron, F.J.M.5    Schoemaker, J.6
  • 67
    • 0023870461 scopus 로고
    • Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease: Indirect evidence for partial gonadotroph desensitization
    • Waldstreicher J, Santoro NF, Hall JE, Filicori M, Crowley Jr WF. 1988 Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease: indirect evidence for partial gonadotroph desensitization. J Clin Endocrinol Metab. 66:165 - 172.
    • (1988) J Clin Endocrinol Metab , vol.66 , pp. 165-172
    • Waldstreicher, J.1    Santoro, N.F.2    Hall, J.E.3    Filicori, M.4    Crowley Jr., W.F.5
  • 68
    • 0026680234 scopus 로고
    • Comparison of luteinizing hormone pulsatility in the serum of women suffering from polycystic ovarian disease using a bioassay and five different immunoassays
    • Imse V, Holzapfel G, Hinney B, Kuhn W, Wuttke W. 1992 Comparison of luteinizing hormone pulsatility in the serum of women suffering from polycystic ovarian disease using a bioassay and five different immunoassays. J Clin Endocrinol Metab. 74:1053 - 1061.
    • (1992) J Clin Endocrinol Metab , vol.74 , pp. 1053-1061
    • Imse, V.1    Holzapfel, G.2    Hinney, B.3    Kuhn, W.4    Wuttke, W.5
  • 69
    • 0842302148 scopus 로고
    • Insulin modulates gonadotropin release and gonadotrope sensitivity to GnRH in polycystic ovary syndrome and normal women
    • Abstract 420
    • Mortola JF, Sathanandan M, Kolterman O, Yen SSC. Insulin modulates gonadotropin release and gonadotrope sensitivity to GnRH in polycystic ovary syndrome and normal women [Abstract 420]. Proc of the Soc for Gynecol Invest. 1989;291.
    • (1989) Proc of the Soc for Gynecol Invest , pp. 291
    • Mortola, J.F.1    Sathanandan, M.2    Kolterman, O.3    Yen, S.S.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.