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Volumn 19, Issue 4, 2005, Pages 275-293

Substance P receptor antagonists in psychiatry: Rationale for development and therapeutic potential

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA ETHYNYL 17BETA HYDROXY 5ALPHA ANDROSTANO[3,2 B]PYRIMIDO[1,2 A]BENZIMIDAZOLE; 2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 (3 OXO 1 PHOSPHORYL 1,2,4 TRIAZOL 5 YLMETHYL)MORPHOLINE; 2 [1 IMINO 2 (2 METHOXYPHENYL)ETHYL] 7,7 DIPHENYLPERHYDROISOINDOL 4 ONE; 2 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 4 (3 OXO 1,2,4 TRIAZOL 5 YLMETHYL) 3 PHENYLMORPHOLINE; 2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; 3 (2 METHOXY 5 TRIFLUOROMETHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; 4 AMINOBUTYRIC ACID; 5 [[2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 MORPHOLINYL]METHYL] N,N DIMETHYL 1H 1,2,3 TRIAZOLE 4 METHANAMINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; APREPITANT; BENZODIAZEPINE DERIVATIVE; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOTROPIN; CYCLIC AMP; FLUOXETINE; FOLLITROPIN; GLUTAMIC ACID; L 759274; LANEPITANT; MONOAMINE OXIDASE INHIBITOR; N BENZYL N2 [4 HYDROXY 1 [(1 METHYL 1H INDOL 3 YL)CARBONYL]PROLYL] N METHYL 3 (2 NAPHTHYL)ALANINAMIDE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR ANTAGONIST; NEUROKININ A; NEUROKININ B; NKP 608; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; OXYTOCIN; PAROXETINE; RP 100893; SAREDUTANT; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; SUBSTANCE P; SUBSTANCE P ANTAGONIST; SUBSTANCE P RECEPTOR; TACHYKININ; THYROTROPIN; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; VOFOPITANT;

EID: 17844404803     PISSN: 11727047     EISSN: None     Source Type: Journal    
DOI: 10.2165/00023210-200519040-00001     Document Type: Review
Times cited : (111)

References (175)
  • 2
    • 0041743145 scopus 로고    scopus 로고
    • The role of peptides in treatment of psychiatric disorders
    • Holsboer F. The role of peptides in treatment of psychiatric disorders. J Neural Transm Suppl 2003; 64: 17-34
    • (2003) J Neural Transm Suppl , vol.64 , pp. 17-34
    • Holsboer, F.1
  • 3
    • 84944496221 scopus 로고
    • An unidentified depressor substance in certain tissue extracts
    • Von Euler US, Gaddum JH. An unidentified depressor substance in certain tissue extracts. J Physiol (Lond) 1931; 72: 74-87
    • (1931) J Physiol (Lond) , vol.72 , pp. 74-87
    • Von Euler, U.S.1    Gaddum, J.H.2
  • 5
    • 0037492613 scopus 로고    scopus 로고
    • Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils
    • Duffy RA, Hedrick JA, Randolph G, et al. Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils. Neuropharmacology 2003; 45: 242-50
    • (2003) Neuropharmacology , vol.45 , pp. 242-250
    • Duffy, R.A.1    Hedrick, J.A.2    Randolph, G.3
  • 6
    • 0037151785 scopus 로고    scopus 로고
    • Identification, localization and receptor characterization of novel mammalian substance P-like peptides
    • Kurtz MM, Wang R, Clements MK, et al. Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene 2002; 296: 205-12
    • (2002) Gene , vol.296 , pp. 205-212
    • Kurtz, M.M.1    Wang, R.2    Clements, M.K.3
  • 7
    • 0000857528 scopus 로고
    • Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A
    • Krause JE, Chirgwin JM, Carter MS, et al. Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A. Proc Natl Acad Sci U S A 1987; 84: 881-5
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 881-885
    • Krause, J.E.1    Chirgwin, J.M.2    Carter, M.S.3
  • 8
    • 0025007380 scopus 로고
    • Identification and cDNA sequence of delta-preprotachykinin, a fourth splicing variant of the rat substance P precursor
    • Harmar AJ, Hyde V, Chapman K. Identification and cDNA sequence of delta-preprotachykinin, a fourth splicing variant of the rat substance P precursor. FEBS Lett 1990; 275: 22-4
    • (1990) FEBS Lett , vol.275 , pp. 22-24
    • Harmar, A.J.1    Hyde, V.2    Chapman, K.3
  • 9
    • 0032476647 scopus 로고    scopus 로고
    • Identification of a delta isoform of preprotachykinin mRNA in human mononuclear phagocytes and lymphocytes
    • Lai JP, Douglas SD, Rappaport E, et al. Identification of a delta isoform of preprotachykinin mRNA in human mononuclear phagocytes and lymphocytes. J Neuroimmunol 1998; 91: 121-8
    • (1998) J Neuroimmunol , vol.91 , pp. 121-128
    • Lai, J.P.1    Douglas, S.D.2    Rappaport, E.3
  • 10
    • 3242795692 scopus 로고
    • Structure and gene organization of bovine neuromedin K precursor
    • Kotani H, Hoshimaru M, Nawa H, et al. Structure and gene organization of bovine neuromedin K precursor. Proc Natl Acad Sci U S A 1986; 83: 7074-8
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 7074-7078
    • Kotani, H.1    Hoshimaru, M.2    Nawa, H.3
  • 11
    • 0034332431 scopus 로고    scopus 로고
    • Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis
    • Zhang Y, Lu L, Furlonger C, et al. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol 2000; 1: 392-7
    • (2000) Nat Immunol , vol.1 , pp. 392-397
    • Zhang, Y.1    Lu, L.2    Furlonger, C.3
  • 13
    • 0019720974 scopus 로고
    • Immunoreactive substance P and serotonin present in the same dense-core vesicles
    • Pelletier G, Steinbusch HW, Verhofstad AA. Immunoreactive substance P and serotonin present in the same dense-core vesicles. Nature 1981; 293: 71-2
    • (1981) Nature , vol.293 , pp. 71-72
    • Pelletier, G.1    Steinbusch, H.W.2    Verhofstad, A.A.3
  • 14
    • 0018316190 scopus 로고
    • Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons
    • Pickel VM, Joh TH, Reis DJ, et al. Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons. Brain Res 1979; 160: 387-400
    • (1979) Brain Res , vol.160 , pp. 387-400
    • Pickel, V.M.1    Joh, T.H.2    Reis, D.J.3
  • 15
    • 0022555285 scopus 로고
    • Exocytosis from large dense cored vesicles as a mechanism for neuropeptide release in the peripheral and central nervous system
    • Thureson-Klein A, Klein RL, Zhu PC. Exocytosis from large dense cored vesicles as a mechanism for neuropeptide release in the peripheral and central nervous system. Scan Electron Microsc 1986; (Pt 1): 179-87
    • (1986) Scan Electron Microsc , Issue.PART 1 , pp. 179-187
    • Thureson-Klein, A.1    Klein, R.L.2    Zhu, P.C.3
  • 16
    • 0030200522 scopus 로고    scopus 로고
    • Ca2+-dependent exocytosis in the somata of dorsal root ganglion neurons
    • Huang LYM, Neher E. Ca2+-dependent exocytosis in the somata of dorsal root ganglion neurons. Neuron 1996; 17: 135-45
    • (1996) Neuron , vol.17 , pp. 135-145
    • Huang, L.Y.M.1    Neher, E.2
  • 17
    • 0028589913 scopus 로고
    • Receptors and antagonists for substance P and related peptides
    • Regoli D, Boudon A, Fauchere JL. Receptors and antagonists for substance P and related peptides. Pharmacol Rev 1994; 46: 551-99
    • (1994) Pharmacol Rev , vol.46 , pp. 551-599
    • Regoli, D.1    Boudon, A.2    Fauchere, J.L.3
  • 18
    • 0027402089 scopus 로고
    • Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist
    • Gether U, Johansen TE, Snider RM, et al. Different binding epitopes on the NK1 receptor for substance P and non-peptide antagonist. Nature 1993; 362: 345-8
    • (1993) Nature , vol.362 , pp. 345-348
    • Gether, U.1    Johansen, T.E.2    Snider, R.M.3
  • 19
    • 0028928491 scopus 로고
    • Rapid endocytosis of a G protein-coupled receptor: Substance P evoked internalization of its receptor in the rat striatum in vivo
    • Mantyh PW, Allen CJ, Ghilardi JR, et al. Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo. Proc Natl Acad Sci U S A 1995; 92: 2622-6
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2622-2626
    • Mantyh, P.W.1    Allen, C.J.2    Ghilardi, J.R.3
  • 20
    • 0029071430 scopus 로고
    • Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor
    • Grady EF, Garland AM, Gamp PD, et al. Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptor. Mol Biol Cell 1995; 6: 509-24
    • (1995) Mol Biol Cell , vol.6 , pp. 509-524
    • Grady, E.F.1    Garland, A.M.2    Gamp, P.D.3
  • 21
    • 0033410218 scopus 로고    scopus 로고
    • The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala
    • Smith DW, Hewson L, Fuller P, et al. The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala. Brain Research 1999; 848: 90-5
    • (1999) Brain Research , vol.848 , pp. 90-95
    • Smith, D.W.1    Hewson, L.2    Fuller, P.3
  • 22
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 1998; 281: 1640-5
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3
  • 23
    • 0022922583 scopus 로고
    • Effect of immobilization stress on neuropeptides and their receptors in rat central nervous system
    • Oct
    • Takayama H, Ota Z, Ogawa N. Effect of immobilization stress on neuropeptides and their receptors in rat central nervous system. Regul Pept 1986 Oct; 15: 239-48
    • (1986) Regul Pept , vol.15 , pp. 239-248
    • Takayama, H.1    Ota, Z.2    Ogawa, N.3
  • 24
    • 0019132584 scopus 로고
    • Acetylcholinesterase hydrolyzes substance P
    • Chubb IW, Hodgson AJ, White GH. Acetylcholinesterase hydrolyzes substance P. Neuroscience 1980; 5: 2065-72
    • (1980) Neuroscience , vol.5 , pp. 2065-2072
    • Chubb, I.W.1    Hodgson, A.J.2    White, G.H.3
  • 25
    • 0028580330 scopus 로고
    • Neuropeptide converting and processing enzymes in the spinal cord and cerebrospinal fluid
    • Persson S, Le Greves P, Thornwall M, et al. Neuropeptide converting and processing enzymes in the spinal cord and cerebrospinal fluid. Prog Brain Res 1995; 104: 111-30
    • (1995) Prog Brain Res , vol.104 , pp. 111-130
    • Persson, S.1    Le Greves, P.2    Thornwall, M.3
  • 27
    • 0002265838 scopus 로고
    • Distribution of substance P and enkephalin immunoreactive neurons and fibers
    • Paxinos G, editor. San Diego (CA): Academic Press
    • Pioro EP, Mai JK, Cuello AC. Distribution of substance P and enkephalin immunoreactive neurons and fibers. In: Paxinos G, editor. The human nervous system. San Diego (CA): Academic Press, 1990: 1051-94
    • (1990) The Human Nervous System , pp. 1051-1094
    • Pioro, E.P.1    Mai, J.K.2    Cuello, A.C.3
  • 28
    • 0023114556 scopus 로고
    • Distribution of substance P-like immunoreactive structures in the brainstem of the adult human brain: An immunocytochemical study
    • Nomura H, Shiosaka S, Tohyama M. Distribution of substance P-like immunoreactive structures in the brainstem of the adult human brain: an immunocytochemical study. Brain Res 1987; 404: 365-70
    • (1987) Brain Res , vol.404 , pp. 365-370
    • Nomura, H.1    Shiosaka, S.2    Tohyama, M.3
  • 29
    • 0030815958 scopus 로고    scopus 로고
    • Localization of neurons expressing substance P and neurokinin B gene transcripts in the human hypothalamus and basal forebrain
    • Chawla MK, Gutierrez GM, Young III WS, et al. Localization . of neurons expressing substance P and neurokinin B gene transcripts in the human hypothalamus and basal forebrain. J Comp Neurol 1997; 384: 429-42
    • (1997) J Comp Neurol , vol.384 , pp. 429-442
    • Chawla, M.K.1    Gutierrez, G.M.2    Young III, W.S.3
  • 30
    • 0029909835 scopus 로고    scopus 로고
    • Modulation of cortical acetylcholine release by serotonin: The role of substance P interneurons
    • Feuerstein TJ, Gleichauf O, Landwehrmeyer GB. Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons. Naunyn Schmiedebergs Arch Pharmacol 1996; 354: 618-26
    • (1996) Naunyn Schmiedebergs Arch Pharmacol , vol.354 , pp. 618-626
    • Feuerstein, T.J.1    Gleichauf, O.2    Landwehrmeyer, G.B.3
  • 31
    • 0024209819 scopus 로고
    • Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkey
    • Battaglia G, Rustioni A. Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkey. J Comp Neurol 1988; 277: 302-12
    • (1988) J Comp Neurol , vol.277 , pp. 302-312
    • Battaglia, G.1    Rustioni, A.2
  • 32
    • 0000205072 scopus 로고
    • Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cord
    • De Biasi S, Rustioni A. Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cord. Proc Natl Acad Sci U S A 1988; 85: 7820-4
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 7820-7824
    • De Biasi, S.1    Rustioni, A.2
  • 33
    • 0023217740 scopus 로고
    • Coexistence of peptides with classical neurotransmitters
    • Hökfelt T, Millhorn D, Seroogy K, et al. Coexistence of peptides with classical neurotransmitters. Experientia 1987; 43 (7): 768-80
    • (1987) Experientia , vol.43 , Issue.7 , pp. 768-780
    • Hökfelt, T.1    Millhorn, D.2    Seroogy, K.3
  • 34
    • 17644433355 scopus 로고    scopus 로고
    • Serotonin and substance P coexist in dorsal raphe neurons of the human brain
    • Sergeyev V, Hökfelt T, Hurd Y. Serotonin and substance P coexist in dorsal raphe neurons of the human brain. Neuroreport 1999; 10: 3967-70
    • (1999) Neuroreport , vol.10 , pp. 3967-3970
    • Sergeyev, V.1    Hökfelt, T.2    Hurd, Y.3
  • 35
    • 0028070434 scopus 로고
    • Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat
    • Nakaya Y, Kaneko T, Shigemoto R, et al. Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J Comp Neurol 1994; 347: 249-74
    • (1994) J Comp Neurol , vol.347 , pp. 249-274
    • Nakaya, Y.1    Kaneko, T.2    Shigemoto, R.3
  • 36
    • 0036448830 scopus 로고    scopus 로고
    • Neurobiology of substance P and the NK1 receptor
    • Mantyh PW. Neurobiology of substance P and the NK1 receptor. J Clin Psychiatry 2002; 63 Suppl. 11: 6-10
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 11 , pp. 6-10
    • Mantyh, P.W.1
  • 37
    • 0026060703 scopus 로고
    • Phylogeny of tachykinin receptor localization in the vertebrate central nervous system: Apparent absence of neurokinin-2 and neurokinin-3 binding sites in the human brain
    • Dietl MM, Palacios JM. Phylogeny of tachykinin receptor localization in the vertebrate central nervous system: apparent absence of neurokinin-2 and neurokinin-3 binding sites in the human brain. Brain Res 1991; 539: 211-22
    • (1991) Brain Res , vol.539 , pp. 211-222
    • Dietl, M.M.1    Palacios, J.M.2
  • 38
    • 0028879442 scopus 로고
    • Regional distribution of substance P binding sites in the brainstem of the human newborn
    • Jordan D, Kermadi I, Rambaud C, et al. Regional distribution of substance P binding sites in the brainstem of the human newborn. Brain Res 1995; 695: 117-24
    • (1995) Brain Res , vol.695 , pp. 117-124
    • Jordan, D.1    Kermadi, I.2    Rambaud, C.3
  • 39
    • 0038054256 scopus 로고    scopus 로고
    • Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain
    • Caberlotto L, Hurd YL, Murdock P, et al. Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain. Eur J Neurosci 2003; 17: 1736-46
    • (2003) Eur J Neurosci , vol.17 , pp. 1736-1746
    • Caberlotto, L.1    Hurd, Y.L.2    Murdock, P.3
  • 40
    • 0034646482 scopus 로고    scopus 로고
    • Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex
    • Tooney PA, Au GG, Chahl LA. Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex. Neurosci Lett 2000; 283: 185-8
    • (2000) Neurosci Lett , vol.283 , pp. 185-188
    • Tooney, P.A.1    Au, G.G.2    Chahl, L.A.3
  • 41
    • 0034604784 scopus 로고    scopus 로고
    • Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: A double immunofluorescence study in the rat
    • Chen LW, Wei LC, Liu HL, et al. Noradrenergic neurons expressing substance P receptor (NK1) in the locus coeruleus complex: a double immunofluorescence study in the rat. Brain Res 2000; 873: 155-9
    • (2000) Brain Res , vol.873 , pp. 155-159
    • Chen, L.W.1    Wei, L.C.2    Liu, H.L.3
  • 42
    • 0037038117 scopus 로고    scopus 로고
    • Modulation of brain stem monoamines and gamma-aminobutyric acid by NK1 receptors in rats
    • Ma QP, Bleasdale C. Modulation of brain stem monoamines and gamma-aminobutyric acid by NK1 receptors in rats. Neuroreport 2002; 13: 1809-12
    • (2002) Neuroreport , vol.13 , pp. 1809-1812
    • Ma, Q.P.1    Bleasdale, C.2
  • 43
    • 0037140795 scopus 로고    scopus 로고
    • Cellular basis for the effects of substance P in the periaqueductal grey and dorsal raphe nucleus
    • Commons KG, Valentine RJ. Cellular basis for the effects of substance P in the periaqueductal grey and dorsal raphe nucleus. J Comp Neurol 2002; 447: 82-97
    • (2002) J Comp Neurol , vol.447 , pp. 82-97
    • Commons, K.G.1    Valentine, R.J.2
  • 44
    • 0022351090 scopus 로고
    • Search for a physiological role of substance P in gastrointestinal motility
    • Bartho L, Holzer P. Search for a physiological role of substance P in gastrointestinal motility. Neuroscience 1985; 16: 1-32
    • (1985) Neuroscience , vol.16 , pp. 1-32
    • Bartho, L.1    Holzer, P.2
  • 45
    • 0027523070 scopus 로고
    • Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium
    • Greeno EW, Mantyh P, Vercellotti GM, et al. Functional neurokinin 1 receptors for substance P are expressed by human vascular endothelium. J Exp Med 1993; 177: 1269-76
    • (1993) J Exp Med , vol.177 , pp. 1269-1276
    • Greeno, E.W.1    Mantyh, P.2    Vercellotti, G.M.3
  • 46
    • 0030791418 scopus 로고    scopus 로고
    • The effects of tachykinins on inflammatory and immune cells
    • Maggi CA. The effects of tachykinins on inflammatory and immune cells. Regul Pept 1997; 70: 75-90
    • (1997) Regul Pept , vol.70 , pp. 75-90
    • Maggi, C.A.1
  • 47
    • 0033954634 scopus 로고    scopus 로고
    • Wind-up of spinal cord neurons and pain sensation: Much ado about something?
    • Herrero JF, Laird JM, Lopez-Garcia JA. Wind-up of spinal cord neurons and pain sensation: much ado about something? Prog Neurobiol 2000; 61: 169-203
    • (2000) Prog Neurobiol , vol.61 , pp. 169-203
    • Herrero, J.F.1    Laird, J.M.2    Lopez-Garcia, J.A.3
  • 48
    • 0031594899 scopus 로고    scopus 로고
    • The tachykinin NK1 receptor. Part II: Distribution and pathophysiological roles
    • Quartara L, Maggi CA. The tachykinin NK1 receptor. Part II: distribution and pathophysiological roles. Neuropeptides 1998; 32: 1-49
    • (1998) Neuropeptides , vol.32 , pp. 1-49
    • Quartara, L.1    Maggi, C.A.2
  • 49
    • 0021847460 scopus 로고
    • Stimulation of connective tissue cell growth by substance P and substance K
    • Nilsson J, von Euler AM, Dalsgaard CJ. Stimulation of connective tissue cell growth by substance P and substance K. Nature 1985;315:61-3
    • (1985) Nature , vol.315 , pp. 61-63
    • Nilsson, J.1    Von Euler, A.M.2    Dalsgaard, C.J.3
  • 50
    • 0024308540 scopus 로고
    • Trophic effect of various neuropeptides on the cultured ventral spinal cord of rat embryo
    • Iwasaki Y, Kinoshita M, Ikeda K, et al. Trophic effect of various neuropeptides on the cultured ventral spinal cord of rat embryo. Neurosci Lett 1989; 101: 316-20
    • (1989) Neurosci Lett , vol.101 , pp. 316-320
    • Iwasaki, Y.1    Kinoshita, M.2    Ikeda, K.3
  • 51
    • 0028912847 scopus 로고
    • Modulation of chemotropism in the developing spinal cord by substance P
    • De Felipe C, Pinnock RD, Hunt SP. Modulation of chemotropism in the developing spinal cord by substance P. Science 1995; 267: 899-902
    • (1995) Science , vol.267 , pp. 899-902
    • De Felipe, C.1    Pinnock, R.D.2    Hunt, S.P.3
  • 52
    • 0030200023 scopus 로고    scopus 로고
    • Effects of substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes: A reexamination
    • Lieb K, Fiebich BL, Busse-Grawitz M, et al. Effects of substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes: a reexamination. J Neuroimmunol 1996; 67: 77-81
    • (1996) J Neuroimmunol , vol.67 , pp. 77-81
    • Lieb, K.1    Fiebich, B.L.2    Busse-Grawitz, M.3
  • 53
    • 0031573083 scopus 로고    scopus 로고
    • The neuropeptide substance P activates transcription factor NF-kappaB and kappaB-dependent gene expression in human astrocytoma cells
    • Lieb K, Fiebich BL, Berger M, et al. The neuropeptide substance P activates transcription factor NF-kappaB and kappaB-dependent gene expression in human astrocytoma cells. J Immunol 1997; 159: 4952-8
    • (1997) J Immunol , vol.159 , pp. 4952-4958
    • Lieb, K.1    Fiebich, B.L.2    Berger, M.3
  • 54
    • 0036721577 scopus 로고    scopus 로고
    • Cellular mechanisms of neurogenic inflammation
    • Richardson JD, Vasko MR. Cellular mechanisms of neurogenic inflammation. J Pharmacol Exp Ther 2002; 302: 839-45
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 839-845
    • Richardson, J.D.1    Vasko, M.R.2
  • 55
    • 0025992860 scopus 로고
    • Substance P and neurodegenerative disorders: A speculative review
    • Barker R. Substance P and neurodegenerative disorders: a speculative review. Neuropeptides 1991; 20: 73-8
    • (1991) Neuropeptides , vol.20 , pp. 73-78
    • Barker, R.1
  • 56
    • 0033457351 scopus 로고    scopus 로고
    • Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists
    • Rupniak NMJ, Kramer MS. Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists. Trends Pharmacol Sci 1999; 20: 485-90
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 485-490
    • Rupniak, N.M.J.1    Kramer, M.S.2
  • 57
    • 0041785431 scopus 로고    scopus 로고
    • Substance P and substance P receptor antagonists in the pathogenesis and treatment of affective disorders
    • Herpfer I, Lieb K. Substance P and substance P receptor antagonists in the pathogenesis and treatment of affective disorders. World J Biol Psychiatry 2003; 4: 56-63
    • (2003) World J Biol Psychiatry , vol.4 , pp. 56-63
    • Herpfer, I.1    Lieb, K.2
  • 58
    • 0036230310 scopus 로고    scopus 로고
    • Elucidating the antidepressant actions of substance P (NK1 receptor) antagonists
    • Rupniak NMJ. Elucidating the antidepressant actions of substance P (NK1 receptor) antagonists. Curr Opin Investig Drugs 2002; 3: 257-61
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 257-261
    • Rupniak, N.M.J.1
  • 59
    • 0022495668 scopus 로고
    • Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin
    • Sep 3
    • Bannon MJ, Deutch AY, Tam SY, et al. Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin. Brain Res 1986 Sep 3; 381: 393-6
    • (1986) Brain Res , vol.381 , pp. 393-396
    • Bannon, M.J.1    Deutch, A.Y.2    Tam, S.Y.3
  • 60
    • 0019863956 scopus 로고
    • Activation by stress of the habenulo-interpeduncular substance P neurons in the rat
    • Aug 7
    • Lisoprawski A, Blanc G, Glowinski J. Activation by stress of the habenulo-interpeduncular substance P neurons in the rat. Neurosci Lett 1981 Aug 7; 25: 47-51
    • (1981) Neurosci Lett , vol.25 , pp. 47-51
    • Lisoprawski, A.1    Blanc, G.2    Glowinski, J.3
  • 61
    • 0021686211 scopus 로고
    • Responsiveness of mesolimbic, mesocortical, septal and hippocampal cholecystokinin and substance P neuronal systems to stress, in the male rat
    • Siegel RA, Düker EM, Fuchs E, et al. Responsiveness of mesolimbic, mesocortical, septal and hippocampal cholecystokinin and substance P neuronal systems to stress, in the male rat. Neurochem Int 1984; 6: 783-9
    • (1984) Neurochem Int , vol.6 , pp. 783-789
    • Siegel, R.A.1    Düker, E.M.2    Fuchs, E.3
  • 62
    • 0023245676 scopus 로고
    • Stress-induced changes in cholecystokinin and substance P concentrations in discrete regions of the rat hypothalamus
    • Jun
    • Siegel RA, Duker EM, Pahnke U, et al. Stress-induced changes in cholecystokinin and substance P concentrations in discrete regions of the rat hypothalamus. Neuroendocrinology 1987 Jun; 46: 75-81
    • (1987) Neuroendocrinology , vol.46 , pp. 75-81
    • Siegel, R.A.1    Duker, E.M.2    Pahnke, U.3
  • 63
    • 0025128372 scopus 로고
    • Effects of whole-body vibration stress on substance P- and neurotensin-like immunoreactivity in the rat brain
    • Aug
    • Nakamura H, Moroji T, Nohara S, et al. Effects of whole-body vibration stress on substance P- and neurotensin-like immunoreactivity in the rat brain. Environ Res 1990 Aug; 52: 155-63
    • (1990) Environ Res , vol.52 , pp. 155-163
    • Nakamura, H.1    Moroji, T.2    Nohara, S.3
  • 64
    • 0028351763 scopus 로고
    • Effects of sequential removal of rats from a group cage, and of individual housing of rats, on substance P, cholecystokinin and somatostatin levels in the periaqueductal grey and limbic regions
    • Apr
    • Brodin E, Rosen A, Schott E, et al. Effects of sequential removal of rats from a group cage, and of individual housing of rats, on substance P, cholecystokinin and somatostatin levels in the periaqueductal grey and limbic regions. Neuropeptides 1994 Apr; 26: 253-60
    • (1994) Neuropeptides , vol.26 , pp. 253-260
    • Brodin, E.1    Rosen, A.2    Schott, E.3
  • 65
    • 0026469024 scopus 로고
    • Short-term restraint stress and s.c. saline injection alter the tissue levels of substance P and cholecystokinin in the peri-aqueductal grey and limbic regions of rat brain
    • Nov
    • Rosen A, Brodin K, Eneroth P, et al. Short-term restraint stress and s.c. saline injection alter the tissue levels of substance P and cholecystokinin in the peri-aqueductal grey and limbic regions of rat brain. Acta Physiol Scand 1992 Nov; 146: 341-8
    • (1992) Acta Physiol Scand , vol.146 , pp. 341-348
    • Rosen, A.1    Brodin, K.2    Eneroth, P.3
  • 66
    • 0028860999 scopus 로고
    • Endogenous substance P inhibits the expression of corticotropin-releasing hormone during a chronic inflammatory stress
    • Chowdrey HS, Larsen PJ, Harbuz MS, et al. Endogenous substance P inhibits the expression of corticotropin-releasing hormone during a chronic inflammatory stress. Life Sci 1995; 57: 2021-9
    • (1995) Life Sci , vol.57 , pp. 2021-2029
    • Chowdrey, H.S.1    Larsen, P.J.2    Harbuz, M.S.3
  • 67
    • 0030877822 scopus 로고    scopus 로고
    • Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: Imaging peptide action in vivo
    • Allen BJ, Rogers SD, Ghilardi JR, et al. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. J Neurosci 1997; 17: 5921-7
    • (1997) J Neurosci , vol.17 , pp. 5921-5927
    • Allen, B.J.1    Rogers, S.D.2    Ghilardi, J.R.3
  • 68
    • 0023677112 scopus 로고
    • Differential response of substance P-containing subtypes of adrenomedullary cells to different stressors
    • Vaupel R, Jarry H, Schlomer HT, et al. Differential response of substance P-containing subtypes of adrenomedullary cells to different stressors. Endocrinology 1988; 123: 2140-5
    • (1988) Endocrinology , vol.123 , pp. 2140-2145
    • Vaupel, R.1    Jarry, H.2    Schlomer, H.T.3
  • 69
    • 1642488331 scopus 로고    scopus 로고
    • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
    • Ebner K, Rupniak NM, Sana A, et al. Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proc Natl Acad Sci U S A 2004; 101: 4280-5
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4280-4285
    • Ebner, K.1    Rupniak, N.M.2    Sana, A.3
  • 70
    • 0023804454 scopus 로고
    • Place aversion induced by the substance P analogue, dimethyl-C7, is not state dependent: Implication of substance P in aversion
    • Elliott PJ. Place aversion induced by the substance P analogue, dimethyl-C7, is not state dependent: implication of substance P in aversion. Exp Brain Research 1988; 73: 354-6
    • (1988) Exp Brain Research , vol.73 , pp. 354-356
    • Elliott, P.J.1
  • 71
    • 0030272419 scopus 로고    scopus 로고
    • Effects of microinjections of the neuropeptide substance P in the dorsal periaqueductal grey on the behaviour of rats in the plus-maze test
    • Aguiar MS, Brandão ML. Effects of microinjections of the neuropeptide substance P in the dorsal periaqueductal grey on the behaviour of rats in the plus-maze test. Physiol Behavior 1996; 60: 1183-6
    • (1996) Physiol Behavior , vol.60 , pp. 1183-1186
    • Aguiar, M.S.1    Brandão, M.L.2
  • 72
    • 0028177366 scopus 로고
    • Conditioned place aversion produced by microinjections of substance P into the periaqueductal grey of rats
    • Aguiar MS, Brandão ML. Conditioned place aversion produced by microinjections of substance P into the periaqueductal grey of rats. Behav Pharmacol 1994; 5: 369-73
    • (1994) Behav Pharmacol , vol.5 , pp. 369-373
    • Aguiar, M.S.1    Brandão, M.L.2
  • 73
    • 0032693056 scopus 로고    scopus 로고
    • Anxiogenic-like effect induced by substance P injected into the lateral septal nucleus
    • Gavioli EC, Canteras NS, De Lima TC. Anxiogenic-like effect induced by substance P injected into the lateral septal nucleus. Neuroreport 1999; 10: 3399-403
    • (1999) Neuroreport , vol.10 , pp. 3399-3403
    • Gavioli, E.C.1    Canteras, N.S.2    De Lima, T.C.3
  • 74
    • 0030571026 scopus 로고    scopus 로고
    • Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice
    • Teixeira RM, Santos AR, Ribeiro SJ, et al. Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice. Eur J Pharmacol 1996; 311: 7-14
    • (1996) Eur J Pharmacol , vol.311 , pp. 7-14
    • Teixeira, R.M.1    Santos, A.R.2    Ribeiro, S.J.3
  • 75
    • 0028067379 scopus 로고
    • Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats
    • Krase W, Koch M, Schnitzler HU. Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats. Behav Brain Res 1994; 63; 81-8
    • (1994) Behav Brain Res , vol.63 , pp. 81-88
    • Krase, W.1    Koch, M.2    Schnitzler, H.U.3
  • 76
    • 0023901814 scopus 로고
    • Increased plasma catecholamines and locomotor activity induced by centrally administered substance P in guinea-pigs
    • Brent PJ, Johnston PA, Chahl LA. Increased plasma catecholamines and locomotor activity induced by centrally administered substance P in guinea-pigs. Neuropharmacology 1988; 27: 743-8
    • (1988) Neuropharmacology , vol.27 , pp. 743-748
    • Brent, P.J.1    Johnston, P.A.2    Chahl, L.A.3
  • 77
    • 0028882435 scopus 로고
    • Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea-pig
    • Piot O, Betschart J, Grail I, et al. Comparative behavioural profile of centrally administered tachykinin NK1, NK2 and NK3 receptor agonists in the guinea-pig. Brit J Pharmacol 1995; 116: 2496-502
    • (1995) Brit J Pharmacol , vol.116 , pp. 2496-2502
    • Piot, O.1    Betschart, J.2    Grail, I.3
  • 78
    • 0028174651 scopus 로고
    • Chromodacryorrhea and repetitive hind paw tapping: Models of peripheral and central tachykinin NK1 receptor activation in gerbils
    • Bristow LJ, Young L. Chromodacryorrhea and repetitive hind paw tapping: models of peripheral and central tachykinin NK1 receptor activation in gerbils. Eur J Pharmacol 1994; 253: 245-52
    • (1994) Eur J Pharmacol , vol.253 , pp. 245-252
    • Bristow, L.J.1    Young, L.2
  • 80
    • 0018778151 scopus 로고
    • Central injection of substance P elicits grooming behavior and motor inhibition in mice
    • Katz RJ. Central injection of substance P elicits grooming behavior and motor inhibition in mice. Neurosci Lett 1979; 12: 133-6
    • (1979) Neurosci Lett , vol.12 , pp. 133-136
    • Katz, R.J.1
  • 81
    • 0026656587 scopus 로고
    • Substance P injection into the dorsal raphe increases blood pressure and serotonin release in hippocampus of conscious rats
    • Gradin K, Qadri F, Nomikos GG, et al. Substance P injection into the dorsal raphe increases blood pressure and serotonin release in hippocampus of conscious rats. Eur J Pharmacol 1992; 218: 363-7
    • (1992) Eur J Pharmacol , vol.218 , pp. 363-367
    • Gradin, K.1    Qadri, F.2    Nomikos, G.G.3
  • 82
    • 0023758981 scopus 로고
    • Substance P induces a cardiovascular defense reaction in the rat: Pharmacological characterization
    • Unger T, Carolus S, Demmert G, et al. Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization. Circ Res 1988; 63: 812-20
    • (1988) Circ Res , vol.63 , pp. 812-820
    • Unger, T.1    Carolus, S.2    Demmert, G.3
  • 83
    • 0026551749 scopus 로고
    • Positively reinforcing effects of the neurokinin substance P in the basal forebrain: Mediation by its C-terminal sequence
    • Hasenöhrl RU, Gerhardt P, Huston JP. Positively reinforcing effects of the neurokinin substance P in the basal forebrain: mediation by its C-terminal sequence. Exp Neurol 1992; 115: 282-91
    • (1992) Exp Neurol , vol.115 , pp. 282-291
    • Hasenöhrl, R.U.1    Gerhardt, P.2    Huston, J.P.3
  • 84
    • 0033007998 scopus 로고    scopus 로고
    • Reinforcing effects of neurokinin substance P in the ventral pallidum: Mediation by the tachykinin NK1 receptor
    • Nikolaus S, Huston JP, Hasenöhrl RU. Reinforcing effects of neurokinin substance P in the ventral pallidum: mediation by the tachykinin NK1 receptor. Eur J Pharmacol 1999; 370: 93-9
    • (1999) Eur J Pharmacol , vol.370 , pp. 93-99
    • Nikolaus, S.1    Huston, J.P.2    Hasenöhrl, R.U.3
  • 85
    • 0344734161 scopus 로고    scopus 로고
    • Anxiolytic-like action of neurokinin substance P administered systemically or into the nucleus basalis magnocellularis region
    • Hasenöhrl RU, Jentjens O, De Souza Silva MA, et al. Anxiolytic-like action of neurokinin substance P administered systemically or into the nucleus basalis magnocellularis region. Eur J Pharmacol 1998; 354: 123-33
    • (1998) Eur J Pharmacol , vol.354 , pp. 123-133
    • Hasenöhrl, R.U.1    Jentjens, O.2    De Souza Silva, M.A.3
  • 86
    • 0037111842 scopus 로고    scopus 로고
    • Diminished anxiety-and depression-related behaviors in mice with selective deletion of the Tac1 gene
    • Nov 15
    • Bilkei-Gorzo A, Racz I, Michel K, et al. Diminished anxiety-and depression-related behaviors in mice with selective deletion of the Tac1 gene. J Neurosci 2002 Nov 15; 22: 10046-52
    • (2002) J Neurosci , vol.22 , pp. 10046-10052
    • Bilkei-Gorzo, A.1    Racz, I.2    Michel, K.3
  • 87
    • 0021137584 scopus 로고
    • Involvement of the D-2 dopamine receptor in the neuroleptic-induced decrease in nigral substance P
    • Oblin A, Zivkovic B, Bartholini G. Involvement of the D-2 dopamine receptor in the neuroleptic-induced decrease in nigral substance P. Eur J Pharmacol 1984; 105: 175-7
    • (1984) Eur J Pharmacol , vol.105 , pp. 175-177
    • Oblin, A.1    Zivkovic, B.2    Bartholini, G.3
  • 88
    • 0027992474 scopus 로고
    • Clomipramine and clonazepam increase cholecystokinin levels in rat ventral tegmental area and limbic regions
    • Brodin K, Ogren SO, Brodin E. Clomipramine and clonazepam increase cholecystokinin levels in rat ventral tegmental area and limbic regions. Eur J Pharmacol 1994; 263: 175-80
    • (1994) Eur J Pharmacol , vol.263 , pp. 175-180
    • Brodin, K.1    Ogren, S.O.2    Brodin, E.3
  • 89
    • 0023230343 scopus 로고
    • Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline
    • Hamon M, Gozlan H, Bourgoin S, et al. Opioid receptors and neuropeptides in the CNS in rats treated chronically with amoxapine or amitriptyline. Neuropharmacology 1987; 26: 531-9
    • (1987) Neuropharmacology , vol.26 , pp. 531-539
    • Hamon, M.1    Gozlan, H.2    Bourgoin, S.3
  • 90
    • 0023191884 scopus 로고
    • Effects of subchronic treatment with imipramine, zimelidine and alaproclate on regional tissue levels of substance P- And neurokinin A/ neurokinin B-like immunoreactivity in the brain and spinal cord of the rat
    • Brodin E, Ogren SO, Theodorsson-Norheim E. Effects of subchronic treatment with imipramine, zimelidine and alaproclate on regional tissue levels of substance P- and neurokinin A/ neurokinin B-like immunoreactivity in the brain and spinal cord of the rat. Neuropharmacology 1987; 26: 581-90
    • (1987) Neuropharmacology , vol.26 , pp. 581-590
    • Brodin, E.1    Ogren, S.O.2    Theodorsson-Norheim, E.3
  • 91
    • 0030580383 scopus 로고    scopus 로고
    • Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat
    • Shirayama Y, Mitsushio H, Takashima M, et al. Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. Brain Res 1996; 739: 70-8
    • (1996) Brain Res , vol.739 , pp. 70-78
    • Shirayama, Y.1    Mitsushio, H.2    Takashima, M.3
  • 92
    • 0029021454 scopus 로고
    • Effects of acute systemic treatment with the 5 HT-uptake blocker alaproclate on tissue levels and release of substance P in rat periaqueductal grey
    • Rosen A, Franck J, Brodin E. Effects of acute systemic treatment with the 5 HT-uptake blocker alaproclate on tissue levels and release of substance P in rat periaqueductal grey. Neuropeptides 1995; 28: 317-24
    • (1995) Neuropeptides , vol.28 , pp. 317-324
    • Rosen, A.1    Franck, J.2    Brodin, E.3
  • 93
    • 0025880670 scopus 로고
    • Serotonin regulation of neostriatal tachykinins following neonatal 6-hydroxydopamine lesions
    • Walker PD, Riley LA, Hart RP, et al. Serotonin regulation of neostriatal tachykinins following neonatal 6-hydroxydopamine lesions. Brain Res 1991; 557: 31-6
    • (1991) Brain Res , vol.557 , pp. 31-36
    • Walker, P.D.1    Riley, L.A.2    Hart, R.P.3
  • 94
    • 0027536167 scopus 로고
    • Serotonin modulates the levels of mRNAS coding for thyrotropin-releasing hormone and preprotachykinin by different mechanisms in medullary raphe neurons
    • Riley LA, Jonakait GM, Hart RP. Serotonin modulates the levels of mRNAS coding for thyrotropin-releasing hormone and preprotachykinin by different mechanisms in medullary raphe neurons. Brain Res Mol Brain Res 1993; 17: 251-7
    • (1993) Brain Res Mol Brain Res , vol.17 , pp. 251-257
    • Riley, L.A.1    Jonakait, G.M.2    Hart, R.P.3
  • 95
    • 1942436848 scopus 로고    scopus 로고
    • Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain
    • Sartori SB, Burnet PW, Sharp T, et al. Evaluation of the effect of chronic antidepressant treatment on neurokinin-1 receptor expression in the rat brain. Neuropharmacology 2004; 46: 1177-83
    • (2004) Neuropharmacology , vol.46 , pp. 1177-1183
    • Sartori, S.B.1    Burnet, P.W.2    Sharp, T.3
  • 96
    • 0021360636 scopus 로고
    • Elevation of substance P-like peptides in the CSF of psychiatric patients
    • Rimon R, Le Greves P, Nyberg F, et al. Elevation of substance P-like peptides in the CSF of psychiatric patients. Biol Psychiatry 1984; 19: 509-16
    • (1984) Biol Psychiatry , vol.19 , pp. 509-516
    • Rimon, R.1    Le Greves, P.2    Nyberg, F.3
  • 97
    • 0025681473 scopus 로고
    • Dynorphin a and substance P in the cerebrospinal fluid of schizophrenic patients
    • Heikkila L, Rimon R, Terenius L. Dynorphin A and substance P in the cerebrospinal fluid of schizophrenic patients. Psychiatry Res 1990; 34: 229-36
    • (1990) Psychiatry Res , vol.34 , pp. 229-236
    • Heikkila, L.1    Rimon, R.2    Terenius, L.3
  • 99
    • 0023885831 scopus 로고
    • Detection of N-terminally extended substance P, but not of substance P in human cerebrospinal fluid - Quantitation with HPLC-RIA
    • Toresson G, Brodin E, Wahlström A, et al. Detection of N-terminally extended substance P, but not of substance P in human cerebrospinal fluid - quantitation with HPLC-RIA. J Neurochem 1988; 50: 1701-7
    • (1988) J Neurochem , vol.50 , pp. 1701-1707
    • Toresson, G.1    Brodin, E.2    Wahlström, A.3
  • 101
    • 0032407940 scopus 로고    scopus 로고
    • Genetics and pathophysiology of affective disorders: Relationship to fibromyalgia
    • Ackenheil M. Genetics and pathophysiology of affective disorders: relationship to fibromyalgia. Z Rheumatol 1998; 57 Suppl. 2: 5-7
    • (1998) Z Rheumatol , vol.57 , Issue.SUPPL. 2 , pp. 5-7
    • Ackenheil, M.1
  • 102
    • 0035990361 scopus 로고    scopus 로고
    • The promise of substance P inhibitors in fibromyalgia
    • Russell IJ. The promise of substance P inhibitors in fibromyalgia. Rheum Dis Clin North Am 2002; 28: 329-42
    • (2002) Rheum Dis Clin North Am , vol.28 , pp. 329-342
    • Russell, I.J.1
  • 103
    • 0028961382 scopus 로고
    • Beta-endorphin, but not substance-P, is increased by acute stress in humans
    • Schedlowski M, Fluge T, Richter S, et al. Beta-endorphin, but not substance-P, is increased by acute stress in humans. Psychoneuroendocrinology 1995; 20: 103-10
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 103-110
    • Schedlowski, M.1    Fluge, T.2    Richter, S.3
  • 104
    • 8944260414 scopus 로고    scopus 로고
    • Studies in psychoneuroimmunology: Psychological, immunological, and neuroendocrinological parameters in Israeli civilians during and after a period of Scud missile attacks
    • Weiss DW, Hirt R, Tarcic N, et al. Studies in psychoneuroimmunology: psychological, immunological, and neuroendocrinological parameters in Israeli civilians during and after a period of Scud missile attacks. Behav Med 1996; 22: 5-14
    • (1996) Behav Med , vol.22 , pp. 5-14
    • Weiss, D.W.1    Hirt, R.2    Tarcic, N.3
  • 105
    • 0037443873 scopus 로고    scopus 로고
    • Substance P serum levels are increased in major depression: Preliminary results
    • Bondy B, Baghai TC, Minov C, et al. Substance P serum levels are increased in major depression: preliminary results. Biol Psychiatry 2003; 53: 538-42
    • (2003) Biol Psychiatry , vol.53 , pp. 538-542
    • Bondy, B.1    Baghai, T.C.2    Minov, C.3
  • 106
    • 4644313502 scopus 로고    scopus 로고
    • Serum levels of substance P and response to antidepressant pharmacotherapy
    • In press
    • Lieb K, Walden J, Grunze H, et al. Serum levels of substance P and response to antidepressant pharmacotherapy. Pharmacopsychiatry. In press
    • Pharmacopsychiatry
    • Lieb, K.1    Walden, J.2    Grunze, H.3
  • 107
    • 22744442604 scopus 로고    scopus 로고
    • Substance P in serum and cerebrospinal fluid of depressed patients: No effect of antidepressant treatment
    • In press
    • Deuschle M, Sander P, Herpfer I, et al. Substance P in serum and cerebrospinal fluid of depressed patients: no effect of antidepressant treatment. Psychiatry Res. In press
    • Psychiatry Res
    • Deuschle, M.1    Sander, P.2    Herpfer, I.3
  • 108
    • 0036152889 scopus 로고    scopus 로고
    • Investigation of substance P transport across the blood-brain barrier
    • Freed AL, Audus KL, Lunte SM. Investigation of substance P transport across the blood-brain barrier. Peptides 2002; 23: 157-65
    • (2002) Peptides , vol.23 , pp. 157-165
    • Freed, A.L.1    Audus, K.L.2    Lunte, S.M.3
  • 109
    • 0028244929 scopus 로고
    • Substance P: Correlation of CSF and plasma levels
    • Clark JW, Senanayake PD, Solomon GD, et al. Substance P: correlation of CSF and plasma levels. Headache 1994; 34: 261-4
    • (1994) Headache , vol.34 , pp. 261-264
    • Clark, J.W.1    Senanayake, P.D.2    Solomon, G.D.3
  • 110
    • 0026602080 scopus 로고
    • Effects of intravenous infusion of substance P on arginine vasopressin and oxytocin secretion in normal men
    • Chiodera P, Coiro V. Effects of intravenous infusion of substance P on arginine vasopressin and oxytocin secretion in normal men. Brain Res 1992; 569: 173-6
    • (1992) Brain Res , vol.569 , pp. 173-176
    • Chiodera, P.1    Coiro, V.2
  • 111
    • 0026446425 scopus 로고
    • Intravenously infused substance P enhances basal and growth hormone (GH) releasing hormone-stimulated GH secretion in normal men
    • Coiro V, Volpi R, Capretti L, et al. Intravenously infused substance P enhances basal and growth hormone (GH) releasing hormone-stimulated GH secretion in normal men. Peptides 1992; 13: 843-6
    • (1992) Peptides , vol.13 , pp. 843-846
    • Coiro, V.1    Volpi, R.2    Capretti, L.3
  • 112
    • 0026629726 scopus 로고
    • Luteinizing hormone response to an intravenous infusion of substance P in normal men
    • Coiro V, Volpi R, Capretti L, et al. Luteinizing hormone response to an intravenous infusion of substance P in normal men. Metabolism 1992; 41: 689-91
    • (1992) Metabolism , vol.41 , pp. 689-691
    • Coiro, V.1    Volpi, R.2    Capretti, L.3
  • 113
    • 0028929968 scopus 로고
    • Effect of substance P on basal and thyrotropin-releasing hormone-stimulated thyrotropin release in humans
    • Coiro V, Volpi R, Capretti L, et al. Effect of substance P on basal and thyrotropin-releasing hormone-stimulated thyrotropin release in humans. Metabolism 1995; 44: 474-7
    • (1995) Metabolism , vol.44 , pp. 474-477
    • Coiro, V.1    Volpi, R.2    Capretti, L.3
  • 114
    • 0026467253 scopus 로고
    • Stimulation of ACTH/ cortisol by intravenously infused substance P in normal men: Inhibition by sodium valproate
    • Coiro V, Capretti L, Volpi R, et al. Stimulation of ACTH/ cortisol by intravenously infused substance P in normal men: inhibition by sodium valproate. Neuroendocrinology 1992; 56: 459-63
    • (1992) Neuroendocrinology , vol.56 , pp. 459-463
    • Coiro, V.1    Capretti, L.2    Volpi, R.3
  • 115
    • 0036900020 scopus 로고    scopus 로고
    • Effects of the neuropeptide substance P on sleep, mood, and neuroendocrine measures in healthy young men
    • Lieb K, Ahlvers K, Dancker K, et al. Effects of the neuropeptide substance P on sleep, mood, and neuroendocrine measures in healthy young men. Neuropsychopharmacol 27; 2002: 1041-9
    • (2002) Neuropsychopharmacol , vol.27 , pp. 1041-1049
    • Lieb, K.1    Ahlvers, K.2    Dancker, K.3
  • 116
    • 0034653187 scopus 로고    scopus 로고
    • Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia
    • Burnet PW, Harrison PJ. Substance P (NK1) receptors in the cingulate cortex in unipolar and bipolar mood disorder and schizophrenia. Biol Psychiatry 2000; 47: 80-3
    • (2000) Biol Psychiatry , vol.47 , pp. 80-83
    • Burnet, P.W.1    Harrison, P.J.2
  • 117
    • 0037007968 scopus 로고    scopus 로고
    • Neurokinin-I receptors are decreased in major depressive disorder
    • Stockmeier CA, Shi X, Konick L, et al. Neurokinin-I receptors are decreased in major depressive disorder. Neuroreport 2002; 13: 1223-7
    • (2002) Neuroreport , vol.13 , pp. 1223-1227
    • Stockmeier, C.A.1    Shi, X.2    Konick, L.3
  • 118
    • 0026099914 scopus 로고
    • A potent nonpeptide antagonist of the substance P (NK1) receptor
    • Snider RM, Constantine JW, Lowe IJ, et al. A potent nonpeptide antagonist of the substance P (NK1) receptor. Science 1991; 251: 435-7
    • (1991) Science , vol.251 , pp. 435-437
    • Snider, R.M.1    Constantine, J.W.2    Lowe, I.J.3
  • 120
    • 0034214841 scopus 로고    scopus 로고
    • NK1 (substance P) receptor antagonists - Why are they not analgesic in humans?
    • Hill R. NK1 (substance P) receptor antagonists - why are they not analgesic in humans? Trends Pharmacol Sci 2000; 21: 244-6
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 122
    • 0036604223 scopus 로고    scopus 로고
    • Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869
    • Van Belle S, Lichinitser MR, Navari RM, et al. Prevention of cisplatin-induced acute and delayed emesis by the selective neurokinin-1 antagonists, L-758,298 and MK-869. Cancer 2002; 94: 3032-41
    • (2002) Cancer , vol.94 , pp. 3032-3041
    • Van Belle, S.1    Lichinitser, M.R.2    Navari, R.M.3
  • 123
    • 0038730808 scopus 로고    scopus 로고
    • Roles of substance P and NK(1) receptor in the brainstem in the development of emesis
    • Saito R, Takano Y, Kamiya HO. Roles of substance P and NK(1) receptor in the brainstem in the development of emesis. J Pharmacol Sci 2003; 91: 87-94
    • (2003) J Pharmacol Sci , vol.91 , pp. 87-94
    • Saito, R.1    Takano, Y.2    Kamiya, H.O.3
  • 124
    • 0031283503 scopus 로고    scopus 로고
    • The tachykinin NK1 receptor. Part I: Ligands and mechanisms of cellular activation
    • Quartara L, Maggi CA. The tachykinin NK1 receptor. Part I: ligands and mechanisms of cellular activation. Neuropeptides 1997; 31: 537-63
    • (1997) Neuropeptides , vol.31 , pp. 537-563
    • Quartara, L.1    Maggi, C.A.2
  • 125
    • 0036760233 scopus 로고    scopus 로고
    • Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity
    • Conley RK, Cumberbatch MJ, Mason GS, et al. Substance P (neurokinin 1) receptor antagonists enhance dorsal raphe neuronal activity. J Neurosci 2002; 22: 7730-6
    • (2002) J Neurosci , vol.22 , pp. 7730-7736
    • Conley, R.K.1    Cumberbatch, M.J.2    Mason, G.S.3
  • 126
    • 0037074949 scopus 로고    scopus 로고
    • Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurons in the locus coeruleus
    • Maubach KA, Martin K, Chicchi G, et al. Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurons in the locus coeruleus. Neuroscience 2002; 109: 609-17
    • (2002) Neuroscience , vol.109 , pp. 609-617
    • Maubach, K.A.1    Martin, K.2    Chicchi, G.3
  • 127
    • 0036132430 scopus 로고    scopus 로고
    • Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801
    • Bert L, Rodier D, Bougault I, et al. Permissive role of neurokinin NK(3) receptors in NK(1) receptor-mediated activation of the locus coeruleus revealed by SR 142801. Synapse 2002; 43: 62-9
    • (2002) Synapse , vol.43 , pp. 62-69
    • Bert, L.1    Rodier, D.2    Bougault, I.3
  • 128
    • 0034719969 scopus 로고    scopus 로고
    • Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons
    • Haddjeri N, Blier P. Effect of neurokinin-I receptor antagonists on the function of 5-HT and noradrenaline neurons. Neuroreport 2000; 11: 1323-7
    • (2000) Neuroreport , vol.11 , pp. 1323-1327
    • Haddjeri, N.1    Blier, P.2
  • 129
    • 0035422889 scopus 로고    scopus 로고
    • Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission
    • Haddjeri N, Blier P. Sustained blockade of neurokinin-1 receptors enhances serotonin neurotransmission. Biol Psychiatry 2001; 50: 191-9
    • (2001) Biol Psychiatry , vol.50 , pp. 191-199
    • Haddjeri, N.1    Blier, P.2
  • 130
    • 0035107206 scopus 로고    scopus 로고
    • Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats
    • Millan MJ, Lejeune F, De Nanteuil G, et al. Selective blockade of neurokinin (NK)(1) receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats. J Neurochem 2001; 76: 1949-54
    • (2001) J Neurochem , vol.76 , pp. 1949-1954
    • Millan, M.J.1    Lejeune, F.2    De Nanteuil, G.3
  • 131
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
    • Santarelli L, Gobbi G, Debs PC, et al. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc Natl Acad Sci U S A 2001; 98: 1912-7
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1912-1917
    • Santarelli, L.1    Gobbi, G.2    Debs, P.C.3
  • 132
    • 0035887916 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P(neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
    • Froger N, Gardier AM, Moratalla R, et al. 5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P(neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. J Neurosci 2001; 21: 8188-97
    • (2001) J Neurosci , vol.21 , pp. 8188-8197
    • Froger, N.1    Gardier, A.M.2    Moratalla, R.3
  • 133
    • 0038718697 scopus 로고    scopus 로고
    • Effects of antidepressant drugs and GR 205171, an neurokinin-1 (NK1) receptor antagonist, on the response in the forced swim test and on monoamine extracellular levels in the frontal cortex of the mouse
    • Zocchi A, Varnier G, Arban R, et al. Effects of antidepressant drugs and GR 205171, an neurokinin-1 (NK1) receptor antagonist, on the response in the forced swim test and on monoamine extracellular levels in the frontal cortex of the mouse. Neurosci Lett 2003; 345: 73-6
    • (2003) Neurosci Lett , vol.345 , pp. 73-76
    • Zocchi, A.1    Varnier, G.2    Arban, R.3
  • 134
    • 0035179732 scopus 로고    scopus 로고
    • Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro
    • Manev H, Uz T, Smalheiser NR, et al. Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro. Eur J Pharmacol 2001; 411: 67-70
    • (2001) Eur J Pharmacol , vol.411 , pp. 67-70
    • Manev, H.1    Uz, T.2    Smalheiser, N.R.3
  • 135
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B, Dowlatshahi D, MacQueen GM, et al. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001; 50: 260-5
    • (2001) Biol Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3
  • 136
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, et al. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002; 22: 3251-61
    • (2002) J Neurosci , vol.22 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3
  • 137
    • 0036734833 scopus 로고    scopus 로고
    • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
    • Lee J, Duan W, Mattson MP. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem 2002; 82: 1367-75
    • (2002) J Neurochem , vol.82 , pp. 1367-1375
    • Lee, J.1    Duan, W.2    Mattson, M.P.3
  • 138
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L, Saxe M, Gross C, et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003; 301: 805-9
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1    Saxe, M.2    Gross, C.3
  • 139
    • 0033970356 scopus 로고    scopus 로고
    • Hippocampal volume reduction in major depression
    • Bremner JD, Narayan M, Anderson ER, et al. Hippocampal volume reduction in major depression. Am J Psychiatry 2000; 157: 115-8
    • (2000) Am J Psychiatry , vol.157 , pp. 115-118
    • Bremner, J.D.1    Narayan, M.2    Anderson, E.R.3
  • 140
    • 0036126742 scopus 로고    scopus 로고
    • The chronic psychosocial stress paradigm in male tree shrews: Evaluation of a novel animal model for depressive disorders
    • van Kampen M, Kramer M, Hiemke C, et al. The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders. Stress 2002; 5: 37-46
    • (2002) Stress , vol.5 , pp. 37-46
    • Van Kampen, M.1    Kramer, M.2    Hiemke, C.3
  • 141
    • 0035940496 scopus 로고    scopus 로고
    • Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
    • Czeh B, Michaelis T, Watanabe T, et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci U S A 2001; 98: 12796-801
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12796-12801
    • Czeh, B.1    Michaelis, T.2    Watanabe, T.3
  • 142
    • 0036428828 scopus 로고    scopus 로고
    • Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume
    • van der Hart MG, Czeh B, de Biurrun G, et al. Substance P receptor antagonist and clomipramine prevent stress-induced alterations in cerebral metabolites, cytogenesis in the dentate gyrus and hippocampal volume. Mol Psychiatry 2002; 7: 933-41
    • (2002) Mol Psychiatry , vol.7 , pp. 933-941
    • Van Der Hart, M.G.1    Czeh, B.2    De Biurrun, G.3
  • 143
    • 0242456101 scopus 로고    scopus 로고
    • Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice
    • Morcuende S, Gadd CA, Peters M, et al. Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice. Eur J Neurosci 2003; 18: 1828-36
    • (2003) Eur J Neurosci , vol.18 , pp. 1828-1836
    • Morcuende, S.1    Gadd, C.A.2    Peters, M.3
  • 144
    • 0026617003 scopus 로고
    • The substance P (NK1) receptor antagonist (+/-)-CP-96,345 causes sedation and motor impairment in Swiss albino mice in the black-and-white box behavioral paradigm
    • Zernig G, Dietrich H, Maggi CA, et al. The substance P (NK1) receptor antagonist (+/-)-CP-96,345 causes sedation and motor impairment in Swiss albino mice in the black-and-white box behavioral paradigm. Neurosci Lett 1992; 143: 169-72
    • (1992) Neurosci Lett , vol.143 , pp. 169-172
    • Zernig, G.1    Dietrich, H.2    Maggi, C.A.3
  • 145
    • 0034057760 scopus 로고    scopus 로고
    • Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice
    • Rupniak NM, Carlson EC, Harrison T, et al. Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice. Neuropharmacology 2000; 39: 1413-21
    • (2000) Neuropharmacology , vol.39 , pp. 1413-1421
    • Rupniak, N.M.1    Carlson, E.C.2    Harrison, T.3
  • 146
    • 0034968997 scopus 로고    scopus 로고
    • Intra-amygdala injection of the substance P [NK(1) receptor] antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs
    • Boyce S, Smith D, Carlson E, et al. Intra-amygdala injection of the substance P [NK(1) receptor] antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs. Neuropharmacology 2001; 41: 130-7
    • (2001) Neuropharmacology , vol.41 , pp. 130-137
    • Boyce, S.1    Smith, D.2    Carlson, E.3
  • 147
    • 0035793345 scopus 로고    scopus 로고
    • Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist
    • Ballard TM, Sanger S, Higgins GA. Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist. Eur J Pharmacol 2001; 412: 255-64
    • (2001) Eur J Pharmacol , vol.412 , pp. 255-264
    • Ballard, T.M.1    Sanger, S.2    Higgins, G.A.3
  • 148
    • 0037334371 scopus 로고    scopus 로고
    • The substance P (NK1) receptor antagonist L-760735 inhibits fear conditioning in gerbils
    • Rupniak NM, Webb JK, Fisher A, et al. The substance P (NK1) receptor antagonist L-760735 inhibits fear conditioning in gerbils. Neuropharmacology 2003; 44: 516-23
    • (2003) Neuropharmacology , vol.44 , pp. 516-523
    • Rupniak, N.M.1    Webb, J.K.2    Fisher, A.3
  • 149
    • 0035218323 scopus 로고    scopus 로고
    • Comparison of the phenotype of NK1R-/- Mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs
    • Rupniak NM, Carlson EJ, Webb JK, et al. Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs. Behav Pharmacol 2001; 12: 497-508
    • (2001) Behav Pharmacol , vol.12 , pp. 497-508
    • Rupniak, N.M.1    Carlson, E.J.2    Webb, J.K.3
  • 150
    • 0033626324 scopus 로고    scopus 로고
    • NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats
    • File SE. NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats. Psychopharmacology 2000; 152: 105-9
    • (2000) Psychopharmacology , vol.152 , pp. 105-109
    • File, S.E.1
  • 151
    • 0035850886 scopus 로고    scopus 로고
    • Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils
    • Cheeta S, Tucci S, Sandhu J, et al. Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils. Brain Res 2001; 915: 170-5
    • (2001) Brain Res , vol.915 , pp. 170-175
    • Cheeta, S.1    Tucci, S.2    Sandhu, J.3
  • 152
    • 0037130347 scopus 로고    scopus 로고
    • Anxiolytic effect of NKP608, a NK1-receptor antagonist, in the social investigation test in gerbils
    • Gentsch C, Cutler M, Vassout A, et al. Anxiolytic effect of NKP608, a NK1-receptor antagonist, in the social investigation test in gerbils. Behav Brain Res 2002; 133: 363-8
    • (2002) Behav Brain Res , vol.133 , pp. 363-368
    • Gentsch, C.1    Cutler, M.2    Vassout, A.3
  • 153
    • 0037151293 scopus 로고    scopus 로고
    • The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P
    • Gavioli EC, Canteras NS, De Lima TCM. The role of lateral septal NK1 receptors in mediating anxiogenic effects induced by intracerebroventricular injection of substance P. Behav Brain Res 2002; 134: 411-5
    • (2002) Behav Brain Res , vol.134 , pp. 411-415
    • Gavioli, E.C.1    Canteras, N.S.2    De Lima, T.C.M.3
  • 154
    • 0033833835 scopus 로고    scopus 로고
    • The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats
    • Papp M, Vassout A, Gentsch C. The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats. Behav Brain Res 2000; 115: 19-23
    • (2000) Behav Brain Res , vol.115 , pp. 19-23
    • Papp, M.1    Vassout, A.2    Gentsch, C.3
  • 155
    • 0344010123 scopus 로고    scopus 로고
    • Involvement of tachykinin NK1 receptor in the behavioral and immunological responses to swimming stress in mice
    • Teixeira RM, De Lima TC. Involvement of tachykinin NK1 receptor in the behavioral and immunological responses to swimming stress in mice. Neuropeptides 2003; 37: 307-15
    • (2003) Neuropeptides , vol.37 , pp. 307-315
    • Teixeira, R.M.1    De Lima, T.C.2
  • 156
    • 0036711388 scopus 로고    scopus 로고
    • The gerbil elevated plus-maze II: Anxiolytic-like effects of selective neurokinin NK1 receptor antagonists
    • Varty GB, Cohen-Williams ME, Morgan CA, et al. The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists. Neuropsychopharmacology 2002; 27: 371-9
    • (2002) Neuropsychopharmacology , vol.27 , pp. 371-379
    • Varty, G.B.1    Cohen-Williams, M.E.2    Morgan, C.A.3
  • 157
    • 0027495531 scopus 로고
    • Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat
    • Shaikh MB, Steinberg A, Siegel A. Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat. Brain Res 1993; 625: 283-94
    • (1993) Brain Res , vol.625 , pp. 283-294
    • Shaikh, M.B.1    Steinberg, A.2    Siegel, A.3
  • 158
    • 0032568444 scopus 로고    scopus 로고
    • Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
    • De Felipe C, Herrero JF, O'Brien JA, et al. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 1998; 392: 394-7
    • (1998) Nature , vol.392 , pp. 394-397
    • De Felipe, C.1    Herrero, J.F.2    O'Brien, J.A.3
  • 159
    • 0036452457 scopus 로고    scopus 로고
    • Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1)
    • Santarelli L, Gobbi G, Blier P, et al. Behavioral and physiologic effects of genetic or pharmacologic inactivation of the substance P receptor (NK1). J Clin Psychiatry 2002; 63 Suppl. 11: 11-7
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 11 , pp. 11-17
    • Santarelli, L.1    Gobbi, G.2    Blier, P.3
  • 160
    • 0034636497 scopus 로고    scopus 로고
    • Rewarding effects of opiates are absent in mice lacking the receptor for substance P
    • Murtra P, Sheasby AM, Hunt SP, et al. Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature 2000; 405: 180-3
    • (2000) Nature , vol.405 , pp. 180-183
    • Murtra, P.1    Sheasby, A.M.2    Hunt, S.P.3
  • 161
    • 0036804846 scopus 로고    scopus 로고
    • Effect of YM992, a novel antidepressant with selective serotonin re-uptake inhibitory and 5-HT 2A receptor antagonistic activity, on a marble-burying behavior test as an obsessive-compulsive disorder model
    • Takeuchi H, Yatsugi S, Yamaguchi T. Effect of YM992, a novel antidepressant with selective serotonin re-uptake inhibitory and 5-HT 2A receptor antagonistic activity, on a marble-burying behavior test as an obsessive-compulsive disorder model. Jpn J Pharmacol 2002; 90: 197-200
    • (2002) Jpn J Pharmacol , vol.90 , pp. 197-200
    • Takeuchi, H.1    Yatsugi, S.2    Yamaguchi, T.3
  • 162
    • 0036239181 scopus 로고    scopus 로고
    • Stereospecific blockade of marble-burying behaviour in mice by selective, non-peptidergic neurokinin1 (NK1) receptor antagonists
    • Millan MJ, Girardon S, Mullot J, et al. Stereospecific blockade of marble-burying behaviour in mice by selective, non-peptidergic neurokinin1 (NK1) receptor antagonists. Neuropharmacology 2002; 42: 677-84
    • (2002) Neuropharmacology , vol.42 , pp. 677-684
    • Millan, M.J.1    Girardon, S.2    Mullot, J.3
  • 163
    • 0141632938 scopus 로고    scopus 로고
    • Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse
    • Gadd CA, Murtra P, De Felipe C, et al. Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse. J Neurosci 2003; 23: 8271-80
    • (2003) J Neurosci , vol.23 , pp. 8271-8280
    • Gadd, C.A.1    Murtra, P.2    De Felipe, C.3
  • 164
    • 0033537751 scopus 로고    scopus 로고
    • Can the placebo be the cure?
    • Enserink M. Can the placebo be the cure? Science 1999; 284: 238-40
    • (1999) Science , vol.284 , pp. 238-240
    • Enserink, M.1
  • 165
    • 0036452132 scopus 로고    scopus 로고
    • Imaging substance P receptors (NK1) in the living human brain using positron emission tomography
    • Hargreaves R. Imaging substance P receptors (NK1) in the living human brain using positron emission tomography. J Clin Psychiatry 2002; 63 Suppl. 11: 18-24
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 11 , pp. 18-24
    • Hargreaves, R.1
  • 166
    • 0034114435 scopus 로고    scopus 로고
    • Validity of clinical trials of antidepressants
    • Quitkin FM, Rabkin JG, Gerald J, et al. Validity of clinical trials of antidepressants. Am J Psychiatry 2000; 157: 327-37
    • (2000) Am J Psychiatry , vol.157 , pp. 327-337
    • Quitkin, F.M.1    Rabkin, J.G.2    Gerald, J.3
  • 167
    • 0036452950 scopus 로고    scopus 로고
    • Clinical experience with substance P receptor (NK1) antagonists in depression
    • Ranga K, Krishnan R. Clinical experience with substance P receptor (NK1) antagonists in depression. J Clin Psychiatry 2002; 63 Suppl. 11: 25-9
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 11 , pp. 25-29
    • Ranga, K.1    Krishnan, R.2
  • 168
    • 10744227469 scopus 로고    scopus 로고
    • Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression
    • Kramer MS, Winokur A, Kelsey J, et al. Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression. Neuropsychopharmacology 2004; 29: 385-92
    • (2004) Neuropsychopharmacology , vol.29 , pp. 385-392
    • Kramer, M.S.1    Winokur, A.2    Kelsey, J.3
  • 169
    • 56149098414 scopus 로고    scopus 로고
    • Effects of CP122721, a selective NK1 receptor antagonist in patients with major depression
    • Jun 12, Boca Raton (FL), USA
    • Chappell P. Effects of CP122721, a selective NK1 receptor antagonist in patients with major depression. Presented at the 42nd annual meeting of the New Clinical Drug Evaluation Unit (NCDEU); 2002 Jun 12, Boca Raton (FL), USA
    • (2002) 42nd Annual Meeting of the New Clinical Drug Evaluation Unit (NCDEU)
    • Chappell, P.1
  • 170
    • 17844407295 scopus 로고    scopus 로고
    • Peptide approaches in the treatment of major depression: Lack of efficacy of the substance P (neurokinin 1 receptor) antagonist aprepitant
    • Montgomery SA, Keller M, Ball W, et al. Peptide approaches in the treatment of major depression: lack of efficacy of the substance P (neurokinin 1 receptor) antagonist aprepitant. Eur Neuropsychopharmacol 2004; 14 (Suppl. 3): S136-37
    • (2004) Eur Neuropsychopharmacol , vol.14 , Issue.SUPPL. 3
    • Montgomery, S.A.1    Keller, M.2    Ball, W.3
  • 171
    • 0034768122 scopus 로고    scopus 로고
    • Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function
    • Steinberg R, Alonso R, Griebel G, et al. Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function. J Pharmacol Exp Ther 2001; 299: 449-58
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 449-458
    • Steinberg, R.1    Alonso, R.2    Griebel, G.3
  • 172
    • 0033120155 scopus 로고    scopus 로고
    • Tachykinin NK(3) receptor involvement in anxiety
    • Ribeiro SJ, Teixeira RM, Calixto JB, et al. Tachykinin NK(3) receptor involvement in anxiety. Neuropeptides 1999; 33: 181-8
    • (1999) Neuropeptides , vol.33 , pp. 181-188
    • Ribeiro, S.J.1    Teixeira, R.M.2    Calixto, J.B.3
  • 173
    • 0033713487 scopus 로고    scopus 로고
    • The psychopharmacology of tachykinin NK-3 receptors in laboratory animals
    • Massi M, Panocka I, de Caro G. The psychopharmacology of tachykinin NK-3 receptors in laboratory animals. Peptides 2000; 21: 1597-609
    • (2000) Peptides , vol.21 , pp. 1597-1609
    • Massi, M.1    Panocka, I.2    De Caro, G.3
  • 174
    • 0242352560 scopus 로고    scopus 로고
    • Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders
    • Holmes A, Heilig M, Rupniak NM, et al. Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders. Trends Pharmacol Sci 2003; 24: 580-8
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 580-588
    • Holmes, A.1    Heilig, M.2    Rupniak, N.M.3
  • 175
    • 0043195904 scopus 로고    scopus 로고
    • Antagonists at the neurokinin receptors: Recent patent literature
    • Giardina GA, Gagliardi S, Martinelli M. Antagonists at the neurokinin receptors: recent patent literature. IDrugs 2003; 6: 758-72
    • (2003) IDrugs , vol.6 , pp. 758-772
    • Giardina, G.A.1    Gagliardi, S.2    Martinelli, M.3


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