Selective blockade of neurokinin-2 receptors produces antidepressant-like effects associated with reduced corticotropin-releasing factor function

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 2, 2001, Pages 449-458

  Steinberg, Régis ^a   Alonso, Richard ^a   Griebel, Guy ^a   Bert, Lionel ^a   Jung, Mireille ^a   Oury Donat, Florence ^a   Poncelet, Martine ^a   Gueudet, Christiane ^a   Desvignes, Christophe ^a   Le Fur, Gérard ^a   Soubrié, Philippe ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLUOXETINE; IMIPRAMINE; NEUROKININ 1 RECEPTOR; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NORADRENALIN; SAREDUTANT; SUBSTANCE P;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; FORCED SWIMMING TEST; GUINEA PIG; HIPPOCAMPUS; LOCUS CERULEUS; MALE; MATERNAL DEPRIVATION; MOUSE; NONHUMAN; NORADRENERGIC SYSTEM; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STRENGTH; VOCALIZATION;

ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BENZAMIDES; BRAIN CHEMISTRY; CORTICOTROPIN-RELEASING HORMONE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GUINEA PIGS; HIPPOCAMPUS; IN SITU HYBRIDIZATION; LOCUS COERULEUS; MATERNAL DEPRIVATION; MICE; MICRODIALYSIS; NOREPINEPHRINE; PIPERIDINES; PREFRONTAL CORTEX; RATS; RECEPTORS, NEUROKININ-2; RNA, MESSENGER; SWIMMING; VOCALIZATION, ANIMAL;

EID: 0034768122     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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