Cooperativity of α-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human

Xenobiotica

Volumn 31, Issue 5, 2001, Pages 265-275

  Emoto, C ^a   Yamazaki, H ^a   Iketaki, H ^a   Yamasaki, S ^a   Satoh, T ^a   Shimizu, R ^a   Suzuki, S ^a   Shimada, N ^a   Nakajima, M ^a   Yokoi, T ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; CYTOCHROME P450 3A; ERYTHROMYCIN; MIDAZOLAM; NIFEDIPINE; TERFENADINE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CALCULATION; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG OXIDATION; ENZYME ASSAY; HUMAN; INTESTINE CELL; LIVER MICROSOME; MOUSE; NONHUMAN;

ANIMALS; BENZOFLAVONES; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ERYTHROMYCIN; GABA MODULATORS; GASTROINTESTINAL AGENTS; HISTAMINE H1 ANTAGONISTS; HUMANS; INHIBITORY CONCENTRATION 50; INTESTINES; KINETICS; MICE; MICROSOMES; MICROSOMES, LIVER; MIDAZOLAM; MIXED FUNCTION OXYGENASES; NIFEDIPINE; OXYGEN; PROTEIN BINDING; STEROID HYDROXYLASES; TERFENADINE; TESTOSTERONE; VASODILATOR AGENTS;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 17844389329     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250110052120     Document Type: Article

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