Prx, Alx, and Shox genes in craniofacial and appendicular development

Advances in Developmental Biology and Biochemistry

Volumn 13, Issue C, 2003, Pages 133-153

  Meijlink, Frits ^a   Kuijper, Sanne ^a   Brouwer, Antje ^a   Kroon, Carla ^a  

^a HUBRECHT INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 17744371097     PISSN: 15691799     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1569-1799(03)13005-5     Document Type: Review

References (67)

1. Amendt B.A., Sutherland L.B., and Russo A.F. Multifunctional role of the Pitx2 homeodomain protein C-terminal tail. Mol. Cell. Biol. 19 (1999) 7001-7010
2. Asbreuk C., van Schaick H., Cox J., Smidt M., and Burbach J. Survey for paired-like homeodomain gene expression in the hypothalamus: restricted expression patterns of Rx, Alx4 and goosecoid. Neuroscience 114 (2002) 883-889
3. Belin V., Cusin V., Viot G., Girlich D., Toutain A., Moncla A., Vekemans M., Le Merrer M., Munnich A., and Cormier-Daire V. SHOX mutations in dyschondrosteosis (Leri-Weill syndrome). Nat. Genet. 19 (1998) 67-69
4. Bergwerff M., Gittenberger-de Groot A.C., DeRuiter M.C., Van Iperen L., Meijlink F., and Poelmann R.E. Patterns of paired-related homeobox genes PRX1 and PRX2 suggest involvement in matrix modulation in the developing chick vascular system. Dev. Dyn. 213 (1998) 59-70
5. Beverdam A., Brouwer A., Reijnen M., Korving J., and Meijlink F. Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice. Development 128 (2001) 3975-3986
6. Beverdam A., and Meijlink F. Expression patterns of group-I aristaless-related genes during craniofacial and limb development. Mech. Dev. 107 (2001) 163-167
7. Blaschke R.J., Monaghan A.P., Schiller S., Schechinger B., Rao E., Padillanash H., Ried T., and Rappold G.A. SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development. Proc. Natl. Acad. Sci. USA 95 (1998) 2406-2411
8. Blaschke, R.J., and Rappold, G.A. 2001. Shox in short stature syndromes. Horm. Res. 55 (suppl.), 21-23
9. Brouwer, A., Ten Berge, D., Wiecherink, R., and Meijlink, F. 2003 The OAR/aristaless domain of the homeodomain protein Cart1 has an attenuating role in vivo. Mech. Dev. 120, 241-252
10. Bürglin, T.R. (2002) http://www.biosci.ki.se/groups/tbu/homeo/classes.gif
11. Capdevila J., and Izpisua B.J. Patterning mechanisms controlling vertebrate limb development. Ann. Rev. Cell. Dev. Biol. 17 (2001) 87-132
12. Chan D.C., Laufer E., Tabin C., and Leder P. Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity. Development 121 (1995) 1971-1978
13. Clement-Jones M., Schiller S., Rao E., Blaschke R.J., Zuniga A., Zeller R., Robson S.C., Binder G., Glass I., Strachan T., Lindsay S., and Rappold G.A. The short stature homeobox gene SHOX is involved in skeletal abnormalities in Turner syndrome. Hum. Mol. Genet. 9 (2000) 695-702
14. Cserjesi P., Lilly B., Bryson L., Wang Y., Sassoon D.A., and Olson E.N. MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer. Development 115 (1992) 1087-1101
15. Forsthoefel P.F. Genetics and manifold effects of Strong's luxoid gene in the mouse, including its interactions with Green's luxoid and Carter's luxate genes. J. Morphol. 118 (1962) 391-420
16. Forsthoefel P.F. The embryological development of the effects of Strong's Luxoid gene in the mouse. J. Morphol. 113 (1963) 427-452
17. Galliot B., de Vargas C., and Miller D. Evolution of homeobox genes: Q50 Paired-like genes founded the Paired class. Dev. Genes. Evol. 209 (1999) 186-197
18. Gauchat D., Kreger S., Holstein T., and Galliot B. Prdl-a, a gene marker for hydra apical differentiation related to triploblastic paired-like head-specific genes. Development 125 (1998) 1637-1645
19. Greer J.M., Puetz J., Thomas K.R., and Capecchi M.R. Maintenance of functional equivalence during paralogous Hox gene evolution. Nature 403 (2000) 661-665
20. Hudson R., Taniguchi-Sidle A., Boras K., Wiggan O., and Hamel P.A. Alx-4, a transcriptional activator whose expression is restricted to sites of epithelial-mesenchymal interactions. Dev. Dyn. 213 (1998) 159-169
21. Jernvall J., and Thesleff I. Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech. Dev. 92 (2000) 19-29
22. Kern M.J., Witte D.P., Valerius M.T., Aronow B.J., and Potter S.S. A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy. Nucleic Acids Res. 20 (1992) 5189-5195
23. Kollar E.J., and Fisher C. Tooth induction in chick epithelium: expression of quiescent genes for enamel synthesis. Science 207 (1980) 993-995
24. Kosho T., Muroya K., Nagai T., Fujimoto M., Yokoya S., Sakamoto H., Hirano T., Terasaki H., Ohashi H., Nishimura G., Sato S., Matsuo N., and Ogata T. Skeletal features and growth patterns in 14 patients with haploinsufficiency of SHOX: implications for the development of Turner syndrome. J. Clin. Endocrinol. Metab. 84 (1999) 4613-4621
25. Leussink B., Brouwer A., El Khattabi M., Poelmann R.E., Gittenberger-de Groot A.C., and Meijlink F. Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain. Mech. Dev. 52 (1995) 51-64
26. Litingtung Y., Dahn R.D., Li Y., Fallon J.F., and Chiang C. Shh and Gli3 are dispensable for skeleton formation but regulate digit number and identity. Nature 418 (2002) 979-983
27. Lu M.F., Cheng H.T., Kern M.J., Potter S.S., Tran B., Diekwisch T.G., and Martin J.F. prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme. Development 126 (1999) 495-504
28. Lu M.F., Cheng H.T., Lacy A.R., Kern M.J., Argao E.A., Potter S.S., Olson E.N., and Martin J.F. Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev. Biol. 205 (1999) 145-157
29. Martin J.F., Bradley A., and Olson E.N. The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev. 9 (1995) 1237-1249
30. Mavrogiannis L.A., Antonopoulou I., Baxova A., Kutilek S., Kim C.A., Sugayama S.M., Salamanca A., Wall S.A., Morriss-Kay G.M., and Wilkie A.O. Haploinsufficiency of the human homeobox gene ALX4 causes skull ossification defects. Nat. Gen. 27 (2001) 17-18
31. Meijlink F., Beverdam A., Brouwer A., Oosterveen T.C., and Ten Berge D. Vertebrate aristaless-related genes. Int. J. Dev. Biol. 43 (1999) 651-663
32. Neubüser A., Peters H., Balling R., and Martin G.R. Antagonistic interactions between FGF and BMP signaling pathways: A mechanism for positioning the sites of tooth formation. Cell 90 (1997) 247-255
33. Norris R.A., and Kern M.J. Identification of domains mediating transcription activation, repression, and inhibition in the paired-related homeobox protein, Prx2 (S8). DNA Cell. Biol. 20 (2001) 89-99
34. Ogata T., Matsuo N., and Nishimura G. SHOX haploinsufficiency and overdosage: impact of gonadal function status. J. Med. Genet. 38 (2001) 1-6
35. Opstelten D.J., Vogels R., Robert B., Kalkhoven E., Zwartkruis F., De Laaf L., Destree O.H., Deschamps J., Lawson K.A., and Meijlink F. The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme. Mech. Dev. 34 (1991) 29-41
36. Peters H., and Balling R. Teeth where and how to make them. Trends Genet. 15 (1999) 59-65
37. Peters H., Neubuser A., Kratochwil K., and Balling R. Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 12 (1998) 2735-2747
38. Qu S., Li L., and Wisdom R. Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein. Gene 203 (1997) 217-223
39. Qu S.M., Niswender K.D., Ji Q.S., Van der Meer R., Keeney D., Magnuson M.A., and Wisdom R. Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. Development 124 (1997) 3999-4008
40. Qu S., Tucker S.C., Ehrlich J.S., Levorse J.M., Flaherty L.A., Wisdom R., and Vogt T.F. Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly. Development 125 (1998) 2711-2721
41. Qu S., Tucker S.C., Zhao Q., Decrombrugghe B., and Wisdom R. Physical and genetic interactions between Alx4 and Cart1. Development 126 (1999) 359-369
42. Rao E., Weiss B., Fukami M., Rump A., Niesler B., Mertz A., Muroya K., Binder G., Kirsch S., Winkelmann M., Nordsiek G., Heinrich U., Breuning M.H., Ranke M.B., Rosenthal A., Ogata T., and Rappold G.A. Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome. Nat. Genet. 16 (1997) 54-63
43. Rappold G.A. The pseudoautosomal regions of the human sex chromosomes. Hum.Genet. 92 (1993) 315-324
44. Schiller S., Spranger S., Schechinger B., Fukami M., Merker S., Drop S.L., Troger J., Knoblauch H., Kunze J., Seidel J., and Rappold G.A. Phenotypic variation and genetic heterogeneity in Leri-Weill syndrome. Eur. J. Hum. Genet. 8 (2000) 54-62
45. Schutte B.C., and Murray J.C. The many faces and factors of orofacial clefts. Hum. Mol. Genet. 8 (1999) 1853-1859
46. Semina E.V., Reiter R.S., and Murray J.C. A new human homeobox gene OGI2X is a member of the most conserved homeobox gene family and is expressed during heart development in mouse. Hum. Mol. Genet. 7 (1998) 415-422
47. St-Jacques B., Hammerschmidt M., and McMahon A.P. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 13 (1999) 2072-2086
48. Strong, L.C. Hardy (1956). L.B.A new "luxoid" mutant in mice. J. Hered. 47, 277-284
49. Sun D., Vanderburg C.R., Odierna G.S., and Hay E.D. TGFbeta3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro. Development 125 (1998) 95-105
50. Takahashi M., Tamura K., Buscher D., Masuya H., Yoneitamura S., Matsumoto K., Naitohmatsuo M., Takeuchi J., Ogura K., Shiroishi T., Ogura T., and Belmonte J.C.I. The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development. Development 125 (1998) 4417-4425
51. Te Welscher P., Fernandez-Teran M., Ros M.A., and Zeller R. Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling. Genes Dev. 16 (2002) 421-426
52. Te Welscher, P., Zuniga, A., Kuijper, S., Drenth, T., Goedemans, H.J., Meijlink, F., Zeller, R. (2002b). Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3. Science 298, 827-830
53. Ten Berge D., Brouwer A., El Bahi S., Guénet J.L., Robert B., and Meijlink F. Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm. Dev. Biol. 199 (1998) 11-25
54. Ten Berge D., Brouwer A., Korving J., Martin J.F., and Meijlink F. Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs. Development 125 (1998) 3831-3842
55. Ten Berge D., Brouwer A., Korving J., Reijnen M.J., van Raaij E.J., Verbeek F., Gaffield W., and Meijlink F. Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis. Development 128 (2001) 2929-2938
56. van Schaick H.S., Smidt M.P., Rovescalli A.C., Luijten M., van der Kleij A.A., Asoh S., Kozak C.A., Nirenberg M., and Burbach J.P. Homeobox gene Prx3 expression in rodent brain and extraneural tissues. Proc. Natl. Acad. Sci. USA 94 (1997) 12993-12998
57. Wang B., Fallon J.F., and Beachy P.A. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100 (2000) 423-434
58. Wimmer K., Zhu X.-X., Rouillard J.M., Ambros P.F., Lamb B.J., Kuick R., Eckart M., Weinhausl A., Fonatsch C., and Hanash S.M. Combined restriction landmark genomic scanning and virtual genome scans identify a novel human homeobox gene, ALX3, that is hypermethylated in neuroblastoma. Genes Chromosomes Cancer 33 (2002) 285-294
59. Wu Y.Q., Badano J.L., McCaskill C., Vogel H., Potocki L., and Shaffer L.G. Haploinsufficiency of ALX4 as a potential cause of parietal foramina in the 11p11.2 contiguous gene-deletion syndrome. Am. J. Hum. Genet. 67 (2000) 1327-1332
60. Wuyts W., Cleiren E., Homfray T., Rasore-Quartino A., Vanhoenacker F., and Van Hul W. The ALX4 homeobox gene is mutated in patients with ossification defects of the skull (foramina parietalia permagna, OMIM 168500). J. Med. Genet. 37 (2000) 916-920
61. Zakany J., Fromentalramain C., Warot X., and Duboule D. Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications. Proc. Natl. Acad. Sci. USA 94 (1997) 13695-13700
62. Zakany J., Gerard M., Favier B., Potter S.S., and Duboule D. Functional equivalence and rescue among group 11 hox gene products in vertebral patterning. Dev. Biol. 176 (1996) 325-328
63. Zhao G.Q., Eberspaecher H., Seldin M.F., and de Crombrugghe B. The gene for the homeodomain-containing protein Cart-1 is expressed in cells that have a chondrogenic potential during embryonic development. Mech. Dev. 48 (1994) 245-254
64. Zhao G.Q., Zhou X., Eberspaecher H., Solursh M., and de Crombrugghe B. Cartilage homeoprotein1, a homeoprotein selectively expressed in chondrocytes. Proc. Natl. Acad. Sci. USA 90 (1993) 8633-8637
65. Zhao Q., Behringer R.R., and Decrombrugghe B. Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nat. Genet. 13 (1996) 275-283
66. Zuniga A., Haramis A.P., McMahon A.P., and Zeller R. Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature 401 (1999) 598-602
67. Zuniga A., and Zeller R. Gli3 (Xt) and formin (Id) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development 126 (1999) 13-21