Rapid communication: Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning

Developmental Biology

Volumn 176, Issue 2, 1996, Pages 325-328

  Zakany J ^a   Gerard M ^a   Favier, B ^b   Potter, S S ^c   Duboule, D ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; MUS MUSCULUS;

GENE PRODUCT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO PATTERN FORMATION; GENE DOSAGE; GENE FUNCTION; HOMEOBOX; LUMBAR VERTEBRA; MOUSE; MOUSE MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPINE; TRANSGENE; TRANSGENIC MOUSE;

EID: 0029898776     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1996.0137     Document Type: Article

References (10)

1. Davis, A. P., Witte, D. P., Hsieh-Li, H. M., Potter, S. S., and Capecchi, M. R. (1995). Absence of radius and ulna in mice lacking Hoxa-11 and Hoxd-11. Nature 375, 791-795.
2. Duboule, D., and Morata, G. (1994). Colinearity and functional hierarchy among genes of the homeotic complexes. Trends Genet. 10, 358-364.
3. Favier, B., LeMeur, M., Chambon, P., and Dollé, P. (1995). Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc. Natl. Acad. Sci. USA 92, 310-314.
4. Favier, B., Rijli, F., Fromental-Ramain, C., Fraulob, V., Chambon, P., and Dollé, P. (1996). Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development 122, 449-460.
5. Fromental-Ramain, C., Warot, X., Lakkaraju, S., Favier, B., Haack, H., Birling, C., Dierich, A., Dollé, P., and Chambon, P. (1996). Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 122, 461-472.
6. Gérard, M., Duboule, D., and Zákány, J. (1993). Structure and activity of regulatory elements involved in the activation of the Hoxd-11 gene during late gastrulation. EMBO J. 12, 3539-3550.
7. Gérard, M., Chen, J. Y., Gronemeyer, H., Chambon, P., Duboule, D., and Zákány, J. (1996). Altered axial patterning in ES cell-derived Hoxd-11 regulatory mutant mice, submitted for publication.
8. Horan, G. S. B., Nagy Kovacs, E., Behringer, R. R., and Featherstone, M. S. (1995). Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: Evidence for unique and redundant function. Dev. Biol. 169, 359-372.
9. Krumlauf, R. (1994). Hox genes in vertebrate development. Cell 78, 191-201.
10. Small, K., and Potter, S. S. (1993). Homeotic transformations and limb defects in Hox A11 mutant mice. Genes Dev. 7, 2318-2328.