Mutations in mouse Aristaless-like4 cause Strong's luxoid polydactyly

Development

Volumn 125, Issue 14, 1998, Pages 2711-2721

  Qu, Shimian ^a   Tucker, S Craig ^a   Ehrlich, Jason S ^b   Levorse, John M ^b   Flaherty, Lorraine A ^c   Wisdom, Ron ^a   Vogt, Thomas F ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PRINCETON UNIVERSITY   (United States)

^c WADSWORTH CENTER   (United States)

Author keywords

Aristaless; Evolution; Limb bud; Mouse; Paired type homeodomain; Pattern formation; Sonic hedgehog; Zone of polarizing activity

Indexed keywords

CHLORAMBUCIL; HOMEODOMAIN PROTEIN;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSSING OVER; EMBRYO PATTERN FORMATION; FEMALE; GENE DELETION; GENE LOCUS; GENE MAPPING; GENE MUTATION; HUMAN; HUMAN CELL; LIMB BUD; LIMB DEVELOPMENT; MALE; MESENCHYME; MOUSE; NEWBORN; NONHUMAN; POLYDACTYLY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CHLORAMBUCIL; CHROMOSOME MAPPING; DROSOPHILA PROTEINS; EVOLUTION; EXTREMITIES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; INSECT PROTEINS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTAGENESIS; POLYDACTYLY; PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TRANS-ACTIVATORS;

ANIMALIA; ERINACEIDAE; MAMMALIA; VERTEBRATA;

EID: 0031875540     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Andrews, N. and Faller, D. (1991). A rapid micropreparation technique for the extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acid Res. 19, 2459.
2. Bedell, M. A., Jenkins, N. A. and Copeland, N. G. (1997). Mouse models of human disease. Part I: Techniques and resources for genetic analysis in mice. Genes Dev. 11, 1-10.
3. Benassayag, C., Seroude, L., Boube, M., Erard, M. and Cribbs, D. L. (1997). A homeodomain point mutation of the Drosophila proboscipedia protein provokes eye loss independently of homeotic function. Mech. Dev. 63, 187-198.
4. Bertuccioli, C., Fasano, L., Jun, S., Wang, S., Sheng, G. and Desplan, C. (1996). In vivo requirement for the paired domain and homeodomain of the paired segmentation gene product. Development 122, 2673-2685.
5. Biesecker, L. G. (1997). Strike three for GLI3. Nature Genetics 17, 259-260.
6. Bruford, E. A., Riise, R., Teague, P. W., Porter, K., Thomson, K. L., Moore, A. T., Jay, M., Warburg, M., Schinzel, A., Tommerup, N., Tornqvist, K., Rosenberg, T., Patton, M., Mansfield, D. C. and Wright, A. F. (1997). Linkage-Mapping in 29 Bardet-Biedl Syndrome Families Confirms Loci in Chromosomal Regions 11q13, 15q22.3-q23, and 16q21. Genomics 41, 93-99.
7. Burglin, T.R. (1994). A comprehensive classification of homeobox genes. In Guidebook to the Homeobox Genes (ed. D. Duboule), pp. 27-71. New York: Oxford University Press.
8. Buscher, D., Bosse, B., Heymer, J. and Ruther, U. (1997). Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb bud development. Mech. Dev. 62, 175-182.
9. Buscher, D. and Ruther, U. (1998). Expression profile of Gli family members and Shh in normal and mutant mouse limb development. Dev Dyn. 211, 88-96.
10. Campbell, G., Weaver, T. and Tomlinson, A. (1993). Axis Specification in the Developing Drosophila Appendage: The Role of wingless, decapentalegic, and the Homeobox Gene aristaless. Cell 74, 1113-1123.
11. Chan, D. C., Laufer, E., Tabin, C. J. and Leder, P. (1995). Polydactylous limbs in Strong's Luxoid mice result from ectopic polarizing activity. Development 121, 1971-78.
12. Charité, J., Graaff, W. d., Shen, S. and Deschamps, J. (1994). Ectopic expression of Hoxb-8 causes duplication of the ZPA in the forelimb and homeotic transformation of axial structures. Cell 78, 589-601.
13. Coates, M. (1994). The Origin of Vertebrate Limbs. Development 1994 Supplement, 169-180.
14. Coates, M. and Clack, J. (1990). Polydactyly in the earliest tetrapod limbs. Nature 347, 66-69.
15. Daeschler, E. B. and Shubin, N. (1998). Fish with fingers? Nature 391, 133.
16. Dietrich, W. M., Miller, J., Steen, R., Merchant, M. A., Damron-Boles, D., Husain, Z., Dredge, R., Daly, M. J., Ingalls, K. A., O'Connor, T. J., Evans, C. A., DeAngelis, M. M., Levinson, D. M., Kruglyak, L., Goodman, N., Copeland, N. G., Jenkins, N. A., Hawkins, T. L., Stein, L., Page, D. C. and Lander, E. S. (1996). A comprehensive genetic map of the mouse genome. Nature 380, 149-152.
17. Dominguez, M., Brunner, M., Hafen, E. and Basler, K. (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein cubitus interruptus. Science 272, 1621-1625.
18. Dunn, N., Winnier, G., Hargett, L., Schrick, J., Fogo, A. and Hogan, B. (1997). Haploinsufficient Phenotypes in Bmp4 Heterozygous Null Mice and Modification by Mutations in Gli3 and Alx4. Dev. Biol. 188, 235-247.
19. Eppig, J. (1997). Mouse Genome Database (MGD): Mouse Genomics Informatics Project. URL: http://www.informatics.jax.org.
20. Flaherty, L., Messer, A., Russell, L. B. and Rinchik, E. M. (1992). Chlorambucil-induced mutations in mice recovered in homozygotes. Proc. Natl. Acad. Sci. USA 89, 2859-2863.
21. Forsthoefel, P. F. (1968). Responses to selection for plus and minus modifiers of some effects of Strong's luxoid gene on the mouse skeleton. Teratology 1, 339-351.
22. Forsthoefel, P. F. (1963). The embryological development of the effects of Strong's luxoid gene in the mouse. J. Morph. 113, 427-452.
23. Forsthoefel, P. F. (1959). The embryological development of the skeletal effects of the luxoid gene in the mouse, including its interactions with the luxate gene. J. Morph. 104, 89-142.
24. Forsthoefel, P. F. (1962). Genetics and manifold effects of Strong's luxoid gene in the mouse, including its interactions with Green's luxoid and Carter's luxate genes. J. Morph. 110, 391-420.
25. Forsthoefel, P. F., Fritts, M. L. and Hatzenbeler, L. J. (1966). The origin and development of alopecia in mice homozygous for Strong's luxoid gene. J. Morph. 118, 565-580.
26. Goodrich, L., Johnson, R., Milenkovic, L., McMahon, J. and Scott, M. (1996). Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by hedgehog. Genes Dev. 10, 301-312.
27. Hinchliffe, J. R. and Johnson, D. R. (1980). The Development of The Vertebrate Limb. New York: Oxford University Press.
28. J mutation contains an intragenic deletion of the Gli3 gene. Nature Genetics 3, 241-246.
29. Johnson, D. R. (1986). The Genetics of the Skeleton New York: Oxford University Press.
30. Johnson, R. and Tabin, C. (1997). Molecular models for vertebrate limb development. Cell 90, 979-990.
31. Krauss, S., Concordet, J.-P. and Ingham, P. W. (1993). A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75, 1431-1444.
32. Lu, H.-C., Revelli, J.-P, Goering, L., Thaller, C. and Eichele, G. (1997). Retinoid signalling is required for the establishment of a ZPA and for the expression of the Hoxb-8, a mediator of ZPA formation. Development 124, 1643-1651.
33. Martin, G. R. (1998). The roles of FGFs in the early development of vertebrate limbs. Genes Dev. (In press).
34. Masuya, H., Sagai, T., Moriwaki, K. and Shiroshi, T. (1997). Multigenic control of the localization of the zone of polarizing activity in limb morphogenesis in the mouse. Dev. Biol. 182, 42-51.
35. Masuya, H., Sagai, T., Wakana, S., Moriwaki, K. and Shiroishi, T. (1995). A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes Dev. 9, 1645-1653.
36. Mathers, P., Grinberg, A., Mahon, K. and Jamrich, M. (1997). The Rx homeobox gene is essential for vertebrate eye development. Nature 387, 603-607.
37. McKusick, V. (1997). Online Mendelian Inheritance in Man (OMIM). URL: http://www.ncbi.nlm.nih.gov/Omim/.
38. Niswander, L. (1997). Limb mutants: what can they tell us about normal limb development? Curr. Opin. Genetics Dev. 7, 530-536.
39. Peichel, C. L., Abbott, C. M. and Vogt, T. F. (1996). Genetic and physical mapping of the mouse Ulnaless locus. Genetics 144, 1757-1767.
40. Petrij, F., Giles, R. H., Dauwerse, H. G., Saris, J. J., Hennekam, R. C. M., Masuno, M., Tommerup, N., Ommen, G.-J. v., Goodman, R. H., Peters, D. J. M. and Breuning, M. H. (1995). Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376, 348-351.
41. Platt, K., Michaud, J. and Joyner, A. (1997). Expression of the mouse Gli and Ptc genes is adjacent to embryonic sources of hedgehog signals suggesting a conservation of pathways between flies and mice. Mech. Dev. 62, 121-135.
42. Qu, S., Niswender, K., Ji, Q., van der Meer, R., Keeney, D., Magnuson, M. and Wisdom, R. (1997). Polydactyly and ectopic ZPA formation in Alx-4 mutant mice. Development 124, 3999-4008.
43. Raff, R. A. (1996). The Shape of Life: Genes, Development, and the Evolution of Animal Form., pp. 355-356. Chicago: University of Chicago Press.
44. Rinchik, E. M., Flaherty, L. and Russell, L. B. (1993). High-frequency induction of chromosomal rearrangements in mouse germ cells by the chemotherapeutic agent chlorambucil. BioEssays 15, 831-876.
45. Rinchik, E. M., Bangham, J. W., Hunsicker, P. R., Cacheiro, N. L. A., Kwon, B. S., Jackson, I. J. and Russell, L. B. (1990). Genetic and molecular analysis of chlorambucil-induced germline mutations in the mouse.Proc. Natl. Acad. Sci. USA 87, 1416-1420.
46. Rowe, L. B., Nadeau, J. H., Turner, R., Frankel, W. N., Letts, V. A., Eppig, J. T., Ko, M. S., Thurston, S. J. and Birkenmeier, E. H. (1994). Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mammalian Genome 5, 253-274.
47. Russell, L. B., Hunsicker, P. R., Cacheiro, N. L. A., Bangham, J. W., Russell, W. L. and Shelby, M. D. (1989). Chlorambucil effectively induces deletion mutations in mouse germ cells. Proc. Natl. Acad. Sci. USA 86, 370-3708.
48. Schimmang, T., Lemaistre, M., Vortkamp, A. and Ruther, U. (1992). Expression of the zinc finger gene Gli3 is affected in the mouse morphogenetic mutant extra-toes (Xt). Development 116, 799-804.
49. Schneitz, K., Spielmann, P. and Noll, M. (1993). Molecular genetics of aristaless, a prd-type homeo box gene involved in the morphogenesis of proximal and distal elements in a subset of appendages in Drosophila. Genes Dev. 7, 114-129.
50. Shizuya, H., Birren, B., Kim, U.-G., Mancino, V., Slepak, T., Tachiri, Y. and Simon, M. (1992). Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. Proc. Natl. Acad. Sci USA 89, 8794-8797.
51. Shubin, N., Tabin, C. and Carroll, S. (1997). Fossils, genes and the evolution of animal limbs. Nature 388, 639-648.
52. Sordino, P., Hoeven, F. v. d. and Duboule, D. (1995). Hox gene expression in teleost fins and the origin of vertebrate digits. Nature 375, 678-681.
53. Stratford, T., Kostakopoulou, K. and Maden, M. (1997). Hoxb-8 has a role in establishing early anterior-posterior polarity in chick forelimb but not hindlimb. Development 124, 4225-4234.
54. Strong, L. C. (1961). The Springville mouse, further observations on a new 'luxoid' mouse. J. Heredity 52, 122-124.
55. Strong, L. C. and Hardy, L. B. (1956). A new 'luxoid' mutant in mice. J. Heredity 47, 277-284.
56. Tickle, C. and Eichele, G. (1994). Vertebrate limb development. Ann. Review of Cell Biol. 10, 121-152.
57. Umesono, K., Murakami, K., Thompson, C. and Evans, R. (1991). Direct repeats as selective response elements for thyroid hormone, retinoic acid, and Vitamin D3 receptors. Cell 65, 1255-1266.
58. Vogt, T. and Leder, P. (1996). Polydactyly in the Strong's luxoid mouse is suppressed by limb deformity alleles. Dev. Genetics 19, 33-42.
59. Vortkamp, A., Franz, T., Gessler, M. and Grzeschik, K.-H. (1992). Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS)and the mouse mutant extra toes (Xt). Mammalian Genome 3, 461-463.
60. Vortkamp, A., Gessler, M. and Grzeschik, K.-H. (1991). GLI3 zinc-finger gene is interrupted by translocations in Greig syndrome families. Nature 352, 539-540.
61. Wilson, D., Guenther, B., Desplan, C. and Kuriyan, J. (1995). High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA. Cell 82, 709-719.
62. Wilson, D., Sheng, G., Lecuit, T., Dostatni, N. and Desplan, C. (1993). Cooperative dimerization of Paired class homeo domains on DNA. Genes Dev. 7, 2120-2134.
63. Zakany, J., Fromental-Ramain, C., Warot, X. and Duboule, D. (1997). Regulation and number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary implications. Proc. Natl. Acad. Sci. USA 94, 13695-13700.
64. Zeller, R., Jackson-Grusby, L. and Leder, P. (1989). The limb deformity gene is required for apical ectodermal ridge differentiation and anteroposterior limb pattern formation. Genes Dev. 3, 1481-1492.
65. Zhao, Q., Behringer, R. and de Crombrugghe, B. (1996). Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nature Genetics 13, 275-283.