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Volumn 287, Issue 1, 1998, Pages 408-415

Targeted delivery of plasmid DNA to hepatocytes in vivo: Optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine) complexes by controlling their physicochemical properties

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; PLASMID DNA; POLYLYSINE;

EID: 0032453959     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (137)

References (41)
  • 1
    • 0023401979 scopus 로고
    • Forces between poly-L-lysine of molecular weight range 4,000-75,000 adsorbed on mica surfaces
    • Afshar-Rad T, Bailey AI, Luckham PF, Macnaughtan W and Chapman D (1987) Forces between poly-L-lysine of molecular weight range 4,000-75,000 adsorbed on mica surfaces. Colloid Surface 25:263-277.
    • (1987) Colloid Surface , vol.25 , pp. 263-277
    • Afshar-Rad, T.1    Bailey, A.I.2    Luckham, P.F.3    Macnaughtan, W.4    Chapman, D.5
  • 2
  • 3
    • 0023603229 scopus 로고
    • Disposition characteristics of mitomycin C-dextran conjugate in normal and tumor-bearing muscles of rabbits
    • Atsumi R, Endo K, Kakutani T, Takakura Y, Hashida M and Sezaki H (1987) Disposition characteristics of mitomycin C-dextran conjugate in normal and tumor-bearing muscles of rabbits. Cancer Res 47:5546-5551.
    • (1987) Cancer Res , vol.47 , pp. 5546-5551
    • Atsumi, R.1    Endo, K.2    Kakutani, T.3    Takakura, Y.4    Hashida, M.5    Sezaki, H.6
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0030865986 scopus 로고    scopus 로고
    • Synthetic polymers for vectorial delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro
    • Dash PR, Toncheva V, Schacht E and Seymour LW (1997) Synthetic polymers for vectorial delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro. J Controlled Release 48:269-276.
    • (1997) J Controlled Release , vol.48 , pp. 269-276
    • Dash, P.R.1    Toncheva, V.2    Schacht, E.3    Seymour, L.W.4
  • 6
    • 0029860513 scopus 로고    scopus 로고
    • Uptake and intracellular trafficking of asialoglycoprotein-polylysine-DNA complexes in isolated rat hepatocytes
    • Edwards RJ, Carpenter DS and Minchin RF (1996) Uptake and intracellular trafficking of asialoglycoprotein-polylysine-DNA complexes in isolated rat hepatocytes. Gene Ther 3:937-940.
    • (1996) Gene Ther , vol.3 , pp. 937-940
    • Edwards, R.J.1    Carpenter, D.S.2    Minchin, R.F.3
  • 7
    • 0029328597 scopus 로고
    • Glycosylated polylysine/DNA complexes: Gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size
    • Erbacher P, Roche AC, Monsigny M and Midoux P (1995) Glycosylated polylysine/DNA complexes: Gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size. Bioconjugate Chem 6:401-410.
    • (1995) Bioconjugate Chem , vol.6 , pp. 401-410
    • Erbacher, P.1    Roche, A.C.2    Monsigny, M.3    Midoux, P.4
  • 8
    • 0027365343 scopus 로고
    • Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor
    • Ferkol T, Kaetzel CS and Davis PB (1993) Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor. J Clin Invest 92:2394-2400.
    • (1993) J Clin Invest , vol.92 , pp. 2394-2400
    • Ferkol, T.1    Kaetzel, C.S.2    Davis, P.B.3
  • 9
    • 0025181633 scopus 로고
    • Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate
    • Fujita T, Yasuda Y, Takakura Y, Hashida M and Sezaki H (1990) Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate. J Controlled Release 11:149-156.
    • (1990) J Controlled Release , vol.11 , pp. 149-156
    • Fujita, T.1    Yasuda, Y.2    Takakura, Y.3    Hashida, M.4    Sezaki, H.5
  • 10
    • 0026980122 scopus 로고
    • Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and poly-saccharide derivatives
    • Fujita T, Nishikawa M, Tamaki C, Takakura Y, Hashida M and Sezaki H (1992) Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and poly-saccharide derivatives. J Pharmacol Exp Ther 263: 971-978.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 971-978
    • Fujita, T.1    Nishikawa, M.2    Tamaki, C.3    Takakura, Y.4    Hashida, M.5    Sezaki, H.6
  • 11
    • 0020435972 scopus 로고
    • Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
    • Gorman CM, Moffat LF and Howard BH (1982) Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044-1051.
    • (1982) Mol Cell Biol , vol.2 , pp. 1044-1051
    • Gorman, C.M.1    Moffat, L.F.2    Howard, B.H.3
  • 12
    • 0021235507 scopus 로고
    • Disposition pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat
    • Hashida M, Kato A, Takakura Y and Sezaki H (1984) Disposition pharmacokinetics of a polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate, in the rat. Drug Metab Dispos 12:492-499.
    • (1984) Drug Metab Dispos , vol.12 , pp. 492-499
    • Hashida, M.1    Kato, A.2    Takakura, Y.3    Sezaki, H.4
  • 13
    • 0031039539 scopus 로고    scopus 로고
    • Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis
    • Hashida M, Hirabayashi H, Nishikawa M and Takakura Y (1997) Targeted delivery of drugs and proteins to the liver via receptor-mediated endocytosis. J Controlled Release 46:129-137.
    • (1997) J Controlled Release , vol.46 , pp. 129-137
    • Hashida, M.1    Hirabayashi, H.2    Nishikawa, M.3    Takakura, Y.4
  • 14
    • 0032580535 scopus 로고    scopus 로고
    • Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine)
    • Hashida M, Takemura S, Nishikawa M and Takakura Y (1998) Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine). J Controlled Release 53:301-310.
    • (1998) J Controlled Release , vol.53 , pp. 301-310
    • Hashida, M.1    Takemura, S.2    Nishikawa, M.3    Takakura, Y.4
  • 15
    • 0029896222 scopus 로고    scopus 로고
    • Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery
    • Hirabayashi H, Nishikawa M, Takakura Y and Hashida M (1996) Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery. Pharm Res 13:880-884.
    • (1996) Pharm Res , vol.13 , pp. 880-884
    • Hirabayashi, H.1    Nishikawa, M.2    Takakura, Y.3    Hashida, M.4
  • 16
    • 0025352717 scopus 로고
    • Evidence for targeted gene transfer by receptor-mediated endocytosis. Stable expression following insulin-directed entry of NEO into HepG2 cells
    • Huckett B, Ariatti M and Hawtrey AO (1990) Evidence for targeted gene transfer by receptor-mediated endocytosis. Stable expression following insulin-directed entry of NEO into HepG2 cells. Biochem Pharmacol 40:253-263.
    • (1990) Biochem Pharmacol , vol.40 , pp. 253-263
    • Huckett, B.1    Ariatti, M.2    Hawtrey, A.O.3
  • 17
    • 0029136052 scopus 로고
    • DNA complexes with polycations for the delivery of genetic materials into cells
    • Kabanov AV and Kabanov VA (1995) DNA complexes with polycations for the delivery of genetic materials into cells. Bioconjugate Chem 6:7-20.
    • (1995) Bioconjugate Chem , vol.6 , pp. 7-20
    • Kabanov, A.V.1    Kabanov, V.A.2
  • 18
    • 0029049810 scopus 로고
    • The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake
    • Kawabata K, Takakura Y and Hashida M (1995) The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake. Pharm Res 12:825-830.
    • (1995) Pharm Res , vol.12 , pp. 825-830
    • Kawabata, K.1    Takakura, Y.2    Hashida, M.3
  • 19
    • 0017201417 scopus 로고
    • 2-Imino-2-methoxyethyl 1-thioglycosides: New reagents for attaching sugars to proteins
    • Lee YC, Stowell CP and Krantz MK (1976) 2-Imino-2-methoxyethyl 1-thioglycosides: New reagents for attaching sugars to proteins. Biochemistry 15:3956-3963.
    • (1976) Biochemistry , vol.15 , pp. 3956-3963
    • Lee, Y.C.1    Stowell, C.P.2    Krantz, M.K.3
  • 20
    • 0029061020 scopus 로고
    • In vivo disposition characteristics of plasmid DNA complexed with cationic liposomes
    • Mahato RI, Kawabata K, Takakura Y and Hashida M (1995a) In vivo disposition characteristics of plasmid DNA complexed with cationic liposomes. J Drug Targeting 3:149-157.
    • (1995) J Drug Targeting , vol.3 , pp. 149-157
    • Mahato, R.I.1    Kawabata, K.2    Takakura, Y.3    Hashida, M.4
  • 21
    • 0028863071 scopus 로고
    • Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes
    • Mahato RI, Kawabata K, Nomura T, Takakura Y and Hashida M (1995b) Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes. J Pharm Sci 84:1267-1271.
    • (1995) J Pharm Sci , vol.84 , pp. 1267-1271
    • Mahato, R.I.1    Kawabata, K.2    Nomura, T.3    Takakura, Y.4    Hashida, M.5
  • 22
    • 0030907837 scopus 로고    scopus 로고
    • Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine)
    • Mahato RI, Takemura S, Akamatsu K, Nishikawa M, Takakura Y and Hashida M (1997) Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine). Biochem Pharmacol 53:887-895.
    • (1997) Biochem Pharmacol , vol.53 , pp. 887-895
    • Mahato, R.I.1    Takemura, S.2    Akamatsu, K.3    Nishikawa, M.4    Takakura, Y.5    Hashida, M.6
  • 24
    • 0027185699 scopus 로고
    • Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting
    • Nishikawa M, Kamijo A, Fujita T, Takakura Y, Sezaki H and Hashida M (1993) Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting. Pharm Res 10:1253-1261.
    • (1993) Pharm Res , vol.10 , pp. 1253-1261
    • Nishikawa, M.1    Kamijo, A.2    Fujita, T.3    Takakura, Y.4    Sezaki, H.5    Hashida, M.6
  • 25
    • 0028967474 scopus 로고
    • Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency
    • Nishikawa M, Hirabayashi H, Takakura Y and Hashida M (1995a) Design for cell-specific targeting of proteins utilizing sugar-recognition mechanism: Effect of molecular weight of proteins on targeting efficiency. Pharm Res 12:209-214.
    • (1995) Pharm Res , vol.12 , pp. 209-214
    • Nishikawa, M.1    Hirabayashi, H.2    Takakura, Y.3    Hashida, M.4
  • 26
    • 0029014068 scopus 로고
    • Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties
    • Nishikawa M, Miyazaki C, Yamashita F, Takakura Y and Hashida M (1995b) Galactosylated proteins are recognized by the liver according to the surface density of galactose moieties. Am J Physiol 268:G849-G856.
    • (1995) Am J Physiol , vol.268
    • Nishikawa, M.1    Miyazaki, C.2    Yamashita, F.3    Takakura, Y.4    Hashida, M.5
  • 28
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
    • Perales JC, Ferkol T, Beegen H, Ratnoff OD and Hanson RW (1994) Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci USA 91:4086-4090.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 29
    • 0030896557 scopus 로고    scopus 로고
    • Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor
    • Perales JC, Grossmann GA, Molas M, Liu G, Ferkol T, Harpst J, Oda H and Hanson RW (1997) Biochemical and functional characterization of DNA complexes capable of targeting genes to hepatocytes via the asialoglycoprotein receptor. J Biol Chem 272:7398-7407.
    • (1997) J Biol Chem , vol.272 , pp. 7398-7407
    • Perales, J.C.1    Grossmann, G.A.2    Molas, M.3    Liu, G.4    Ferkol, T.5    Harpst, J.6    Oda, H.7    Hanson, R.W.8
  • 32
    • 0029895325 scopus 로고    scopus 로고
    • Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution
    • Takakura Y and Hashida M (1996) Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution. Pharm Res 13: 820-831.
    • (1996) Pharm Res , vol.13 , pp. 820-831
    • Takakura, Y.1    Hashida, M.2
  • 33
    • 0025148495 scopus 로고
    • Disposition characteristics of macromolecules in tumor-bearing mice
    • Takakura Y, Fujita T, Hashida M and Sezaki H (1990) Disposition characteristics of macromolecules in tumor-bearing mice. Pharm Res 7:339-346.
    • (1990) Pharm Res , vol.7 , pp. 339-346
    • Takakura, Y.1    Fujita, T.2    Hashida, M.3    Sezaki, H.4
  • 34
    • 0028351444 scopus 로고
    • Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors
    • Takakura Y, Fujita T, Furitsu H, Nishikawa M, Sezaki H and Hashida M (1994) Pharmacokinetics of succinylated proteins and dextran sulfate in mice: Implications for hepatic targeting of protein drugs by direct succinylation via scavenger receptors. Int J Pharm 105:19-29.
    • (1994) Int J Pharm , vol.105 , pp. 19-29
    • Takakura, Y.1    Fujita, T.2    Furitsu, H.3    Nishikawa, M.4    Sezaki, H.5    Hashida, M.6
  • 35
    • 0029294596 scopus 로고
    • Targeted gene delivery with a low molecular weight glycopeptide carrier
    • Wadhwa MS, Knoell DL, Young AP and Rice KG (1995) Targeted gene delivery with a low molecular weight glycopeptide carrier. Bioconjugate Chem 6:283-291.
    • (1995) Bioconjugate Chem , vol.6 , pp. 283-291
    • Wadhwa, M.S.1    Knoell, D.L.2    Young, A.P.3    Rice, K.G.4
  • 37
    • 0021858187 scopus 로고
    • The liver sieve: Considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse
    • Wisse E, De Zanger RB, Charels K, Van Der Smissen P and McCuskey RS (1985) The liver sieve: Considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse. Hepatology 5:683-692.
    • (1985) Hepatology , vol.5 , pp. 683-692
    • Wisse, E.1    De Zanger, R.B.2    Charels, K.3    Van Der Smissen, P.4    McCuskey, R.S.5
  • 38
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transfections by a soluble DNA carrier complexes
    • Wu GY and Wu CH (1986) Receptor-mediated in vitro gene transfections by a soluble DNA carrier complexes. J Biol Chem 262:4429-4432.
    • (1986) J Biol Chem , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 39
    • 0023811723 scopus 로고
    • Receptor-mediated gene delivery and expression in vivo
    • Wu GY and Wu CH (1991) Receptor-mediated gene delivery and expression in vivo. J Biol Chem 263:14621-14624.
    • (1991) J Biol Chem , vol.263 , pp. 14621-14624
    • Wu, G.Y.1    Wu, C.H.2
  • 40
    • 0019854279 scopus 로고
    • A pharmacokinetic analysis program (MULTI) for microcomputer
    • Yamaoka K, Tanigawara Y, Tanaka H and Uno Y (1981) A pharmacokinetic analysis program (MULTI) for microcomputer. J Pharmacobio-Dyn 4:879-885.
    • (1981) J Pharmacobio-Dyn , vol.4 , pp. 879-885
    • Yamaoka, K.1    Tanigawara, Y.2    Tanaka, H.3    Uno, Y.4
  • 41
    • 0027313072 scopus 로고
    • Systemic gene expression after intravenous DNA delivery into adult mice
    • Zhu N, Liggitt D, Liu Y and Debs R (1993) Systemic gene expression after intravenous DNA delivery into adult mice. Science 261:209-211.
    • (1993) Science , vol.261 , pp. 209-211
    • Zhu, N.1    Liggitt, D.2    Liu, Y.3    Debs, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.