Mutational analysis of target enzyme recognition of the β-trefoil fold barley α-amylase/subtilisin inhibitor

Journal of Biological Chemistry

Volumn 280, Issue 15, 2005, Pages 14855-14864

  Bønsager, Birgit C ^a,b   Nielsen, Peter K ^a,c   Hachem, Maher Abou ^a,b   Fukuda, Kenji ^a,b,d   Prætorius Ibba, Mette ^a,e   Svensson, Birte ^a,b  

^a CARLSBERG LABORATORY   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c NOVO NORDISK A S   (Denmark)

^d OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENZYME INHIBITION; ENZYME KINETICS; INTERFACES (MATERIALS); MUTAGENESIS; POSITIVE IONS;

ENZYME RECOGNITION; GLYCOSIDE HYDROLASE; MUTATION; PROTEASE INHIBITION;

ENZYMES;

ALBUMINOID; AMYLASE; BARLEY ALPHA AMYLASE SUBTILISIN INHIBITOR; CALCIUM ION; PROTEIN INHIBITOR; PROTEINASE; STARCH; SUBTILISIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; INTERMETHOD COMPARISON; KINETICS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN VARIANT; SENSITIVITY ANALYSIS; SOLVATION; SURFACE PLASMON RESONANCE; WILD TYPE;

ALPHA-AMYLASE; AMINO ACID SEQUENCE; BINDING SITES; CALCIUM; CATALYTIC DOMAIN; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSIDE HYDROLASES; HORDEUM; ISOELECTRIC FOCUSING; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SOFTWARE; STEREOISOMERISM; SUBTILISIN; SURFACE PLASMON RESONANCE; THERMODYNAMICS; TIME FACTORS;

HORDEUM VULGARE SUBSP. VULGARE; LOTUS;

EID: 17644379997     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412222200     Document Type: Article

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