메뉴 건너뛰기




Volumn 124, Issue 10, 2005, Pages 388-395

Adiponectin: A new link between obesity, insulin resistance and cardiovascular disease;Adiponectina: Un nuevo nexo entre obesidad, resistencia a la insulina y enfermedad cardiovascular

Author keywords

Adiponectin; Atherosclerosis; Insulin resistance; Obesity; Type 2 diabetes

Indexed keywords

ADIPONECTIN; ANTIOBESITY AGENT; CELL ADHESION MOLECULE; TUMOR NECROSIS FACTOR ALPHA;

EID: 17144392614     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1157/13072576     Document Type: Review
Times cited : (42)

References (58)
  • 1
    • 0037732481 scopus 로고    scopus 로고
    • The adipocyte in insulin resistance? key molecules and the impact of the thiazolidinediones
    • Arner P. The adipocyte in insulin resistance? key molecules and the impact of the thiazolidinediones. Trends Endocrinol Metab 2003;14:137-45.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 137-145
    • Arner, P.1
  • 2
    • 0037296946 scopus 로고    scopus 로고
    • Adiponectin and resistin - New hormones of white adipose tissue
    • Beltowski J. Adiponectin and resistin - new hormones of white adipose tissue. Med Sci Monit 2003;9:55RA-61.
    • (2003) Med Sci Monit , vol.9
    • Beltowski, J.1
  • 5
    • 0037342120 scopus 로고    scopus 로고
    • Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy
    • Phillips SA, Ciaraldi TP, Kong APS, Bandukwala R, Aroda V, Carter L, et al. Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy. Diabetes 2003;52:667-74.
    • (2003) Diabetes , vol.52 , pp. 667-674
    • Phillips, S.A.1    Ciaraldi, T.P.2    Kong, A.P.S.3    Bandukwala, R.4    Aroda, V.5    Carter, L.6
  • 6
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant Gene transcript 1)
    • Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (Adipose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996;221:286-9.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 7
    • 0029836585 scopus 로고    scopus 로고
    • Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
    • Nakano Y, Tobe T, Choi-Miura NH, Mazda T, Tomita T. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 1996;20:803-12.
    • (1996) J Biochem , vol.20 , pp. 803-812
    • Nakano, Y.1    Tobe, T.2    Choi-Miura, N.H.3    Mazda, T.4    Tomita, T.5
  • 8
  • 9
    • 17544382289 scopus 로고    scopus 로고
    • AdipoQ is a novel adipose-specific gene dysregulated in obesity
    • Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 1996;271:10697-703.
    • (1996) J Biol Chem , vol.271 , pp. 10697-10703
    • Hu, E.1    Liang, P.2    Spiegelman, B.M.3
  • 10
    • 0037205414 scopus 로고    scopus 로고
    • Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin
    • Wang Y, Xu A, Knight C, Xu LX, Cooper GJS. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin. J Biol Chem 2002;277:19521-9.
    • (2002) J Biol Chem , vol.277 , pp. 19521-19529
    • Wang, Y.1    Xu, A.2    Knight, C.3    Xu, L.X.4    Cooper, G.J.S.5
  • 11
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001;98:2005-10.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2005-2010
    • Fruebis, J.1    Tsao, T.S.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.5    Yen, F.T.6
  • 12
    • 0037119375 scopus 로고    scopus 로고
    • Oligomerization state-dependent activation of NF-kB signalling pathway by adipocyte complement-related protein of 30 kDa (Acrp30)
    • Tsao TS, Murrey HE, Hug C, Lee DH, Lodish HF. Oligomerization state-dependent activation of NF-kB signalling pathway by adipocyte complement-related protein of 30 kDa (Acrp30). J Biol Chem 2002;277:29359-62.
    • (2002) J Biol Chem , vol.277 , pp. 29359-29362
    • Tsao, T.S.1    Murrey, H.E.2    Hug, C.3    Lee, D.H.4    Lodish, H.F.5
  • 15
    • 0345275792 scopus 로고    scopus 로고
    • Adiponectin in a native Canadian population experiencing rapid epidemiological transition
    • Hanley AJG, Connelly PW, Harris SB, Zinman B. Adiponectin in a native Canadian population experiencing rapid epidemiological transition. Diabetes Care 2003;26:3219-25.
    • (2003) Diabetes Care , vol.26 , pp. 3219-3225
    • Hanley, A.J.G.1    Connelly, P.W.2    Harris, S.B.3    Zinman, B.4
  • 17
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone Adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Kaki H, Terauchi Y, Kubota N, Hara K, et al. The fat-derived hormone Adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7:941-6.
    • (2001) Nat Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Kaki, H.3    Terauchi, Y.4    Kubota, N.5    Hara, K.6
  • 18
    • 0037494960 scopus 로고    scopus 로고
    • Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
    • Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects. Nature 2003;423:762-9.
    • (2003) Nature , vol.423 , pp. 762-769
    • Yamauchi, T.1    Kamon, J.2    Ito, Y.3    Tsuchida, A.4    Yokomizo, T.5    Kita, S.6
  • 20
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K, Funahashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 2001;50:1126-33.
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6
  • 21
    • 0242304261 scopus 로고    scopus 로고
    • Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus
    • Yatagai T, Nagasaka S, Taniguchi A, Fukushima M, Nakamura T, Kuroe A, et al. Hypoadiponectinemia is associated with visceral fat accumulation and insulin resistance in Japanese men with type 2 diabetes mellitus. Metabolism 2003;52:1274-8.
    • (2003) Metabolism , vol.52 , pp. 1274-1278
    • Yatagai, T.1    Nagasaka, S.2    Taniguchi, A.3    Fukushima, M.4    Nakamura, T.5    Kuroe, A.6
  • 22
    • 17944362243 scopus 로고    scopus 로고
    • The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome
    • Comuzzie AG, Funahashi T, Sonnenberg G, Martin U, Jacob HJ, Black AE, et al. The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab 2001;86:4321-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4321-4325
    • Comuzzie, A.G.1    Funahashi, T.2    Sonnenberg, G.3    Martin, U.4    Jacob, H.J.5    Black, A.E.6
  • 23
    • 0842328001 scopus 로고    scopus 로고
    • Update on adipocyte hormones. Regulation of energy balance and carbohvdrate/lioid metabolism
    • Havel PJ. Update on adipocyte hormones. Regulation of energy balance and carbohvdrate/lioid metabolism. Diabetes 2004;53:5143-51.
    • (2004) Diabetes , vol.53 , pp. 5143-5151
    • Havel, P.J.1
  • 26
    • 0035377048 scopus 로고    scopus 로고
    • Diabetes mellitus, inflamación y aterosclerosis coronaria: Perspectiva actual y futura
    • Sánchez-Recalde Á, Kaski JC. Diabetes mellitus, inflamación y aterosclerosis coronaria: perspectiva actual y futura. Rev Esp Cardiol 2001;54:751-63.
    • (2001) Rev Esp Cardiol , vol.54 , pp. 751-763
    • Sánchez-Recalde, Á.1    Kaski, J.C.2
  • 29
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001;86:1930-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3    Hotta, K.4    Matsuzawa, Y.5    Pratley, R.E.6
  • 32
    • 0036728279 scopus 로고    scopus 로고
    • Elevated serum concentration of adipose-derived factor, adiponectin, in patients with type 1 diabetes
    • Imagawa A, Funahashi T, Nakamura T, Noriwaki M, Tanaka S, Hishizawa H, et al. Elevated serum concentration of adipose-derived factor, adiponectin, in patients with type 1 diabetes. Diabetes Care 2002;25:1665-6.
    • (2002) Diabetes Care , vol.25 , pp. 1665-1666
    • Imagawa, A.1    Funahashi, T.2    Nakamura, T.3    Noriwaki, M.4    Tanaka, S.5    Hishizawa, H.6
  • 34
    • 0033538869 scopus 로고    scopus 로고
    • Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4
    • Bogan JS, Lodish HF. Two compartments for insulin-stimulated exocytosis in 3T3-L1 adipocytes defined by endogenous ACRP30 and GLUT4. J Cell Biol 1999;146:609-20.
    • (1999) J Cell Biol , vol.146 , pp. 609-620
    • Bogan, J.S.1    Lodish, H.F.2
  • 35
    • 0032762661 scopus 로고    scopus 로고
    • Insulin signalling and action in fat cells: Associations with insulin resistance and type 2 diabetes
    • Smith U, Axelsen M, Carvalho E, Eliasson B, Jansson PA, Wesslau C. Insulin signalling and action in fat cells: associations with insulin resistance and type 2 diabetes. Ann NY Acad Sci 1999;892:119-26.
    • (1999) Ann NY Acad Sci , vol.892 , pp. 119-126
    • Smith, U.1    Axelsen, M.2    Carvalho, E.3    Eliasson, B.4    Jansson, P.A.5    Wesslau, C.6
  • 36
    • 0036061598 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population
    • Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, et al. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002;51:536-40.
    • (2002) Diabetes , vol.51 , pp. 536-540
    • Hara, K.1    Boutin, P.2    Mori, Y.3    Tobe, K.4    Dina, C.5    Yasuda, K.6
  • 38
    • 0036091918 scopus 로고    scopus 로고
    • Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: Interaction with family history of type 2 diabetes
    • Stumvoll M, Tschritter O, Pritsche A, Staiger H, Renn W, Weisser M, et al. Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Diabetes 2002;51:37-41.
    • (2002) Diabetes , vol.51 , pp. 37-41
    • Stumvoll, M.1    Tschritter, O.2    Pritsche, A.3    Staiger, H.4    Renn, W.5    Weisser, M.6
  • 39
    • 0242329843 scopus 로고    scopus 로고
    • Adiponectin: Linking the fat cell to insulin sensitivity
    • Goldfine AB, Kahn CR. Adiponectin: linking the fat cell to insulin sensitivity. Lancet 2003;362:1431-2.
    • (2003) Lancet , vol.362 , pp. 1431-1432
    • Goldfine, A.B.1    Kahn, C.R.2
  • 40
    • 0347990597 scopus 로고    scopus 로고
    • Genetic variation at the adiponectin locus and risk of type 2 diabetes in women
    • Hu FB, Doria A, Li T, Meigs JB, Liu S, Memisoglu A. Genetic variation at the adiponectin locus and risk of type 2 diabetes in women. Diabetes 2004;53:209-13.
    • (2004) Diabetes , vol.53 , pp. 209-213
    • Hu, F.B.1    Doria, A.2    Li, T.3    Meigs, J.B.4    Liu, S.5    Memisoglu, A.6
  • 41
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • Díez JJ, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol 2003;148:293-300.
    • (2003) Eur J Endocrinol , vol.148 , pp. 293-300
    • Díez, J.J.1    Iglesias, P.2
  • 42
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and β-cell dysfunction
    • Boden G, Shulman Gl. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β-cell dysfunction. Eur J Clin Invest 2002;32:14-23.
    • (2002) Eur J Clin Invest , vol.32 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 43
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and the metabolic syndrome
    • Moller DE. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 2001;414:821-7.
    • (2001) Nature , vol.414 , pp. 821-827
    • Moller, D.E.1
  • 44
    • 0347986520 scopus 로고    scopus 로고
    • Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR
    • Chinetti G, Zawadski C, Fruchart JC, Staelos B. Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR. Biochem Biophys Res Commun 2004;314:151-8.
    • (2004) Biochem Biophys Res Commun , vol.314 , pp. 151-158
    • Chinetti, G.1    Zawadski, C.2    Fruchart, J.C.3    Staelos, B.4
  • 45
  • 46
    • 0034471789 scopus 로고    scopus 로고
    • Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor alpha on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes
    • Kappes A, Loffler G. Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor alpha on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes. Hormone Metab Res 2000;32:548-54.
    • (2000) Hormone Metab Res , vol.32 , pp. 548-554
    • Kappes, A.1    Loffler, G.2
  • 47
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999;100:2473-6.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 48
    • 0842332231 scopus 로고    scopus 로고
    • Adiponectin suppresses proliferation and Superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL
    • Motoshima H, Wu X, Mahadev K, Goldstein BJ. Adiponectin suppresses proliferation and Superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL. Biochem Biophys Res Commun 2004;315:264-71.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 264-271
    • Motoshima, H.1    Wu, X.2    Mahadev, K.3    Goldstein, B.J.4
  • 49
    • 0034641647 scopus 로고    scopus 로고
    • Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappa B signalling through cAMP-dependent pathway
    • Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappa B signalling through cAMP-dependent pathway. Circulation 2000;102:1296-301.
    • (2000) Circulation , vol.102 , pp. 1296-1301
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Okamoto, Y.4    Maeda, K.5    Kuriyama, H.6
  • 50
    • 0035955760 scopus 로고    scopus 로고
    • Novel clinical markers of vascular wall inflammation
    • Blake GJ, Ridker PM. Novel clinical markers of vascular wall inflammation. Cir Res 2001;89:763-71.
    • (2001) Cir Res , vol.89 , pp. 763-771
    • Blake, G.J.1    Ridker, P.M.2
  • 53
    • 0034284038 scopus 로고    scopus 로고
    • Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages
    • Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama A, Ouchi N, et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 2000;96:1723-32.
    • (2000) Blood , vol.96 , pp. 1723-1732
    • Yokota, T.1    Oritani, K.2    Takahashi, I.3    Ishikawa, J.4    Matsuyama, A.5    Ouchi, N.6
  • 54
    • 0037129861 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, acts as a platelet-derived growth factor-BB binding protein, and regulates growth factor-induced common post-receptor signal in vascular smooth muscle cell
    • Arita Y, Kihara S, Ouchi N, Maeda K, Kuriyama H, Okamoto Y, et al. Adipocyte-derived plasma protein, adiponectin, acts as a platelet-derived growth factor-BB binding protein, and regulates growth factor-induced common post-receptor signal in vascular smooth muscle cell. Circulation 2002;105:2893-8.
    • (2002) Circulation , vol.105 , pp. 2893-2898
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 55
    • 0035957040 scopus 로고    scopus 로고
    • Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages
    • Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Okamoto Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 2001;103:1057-63.
    • (2001) Circulation , vol.103 , pp. 1057-1063
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Nishida, M.4    Matsuyama, A.5    Okamoto, Y.6
  • 56
    • 0642307072 scopus 로고    scopus 로고
    • Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus
    • Esposito K, Nappo F, Giugliano F, Di Palo C, Ciotola M, Barbieri M, et al. Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. Am J Clin Nut 2003;78:1135-40.
    • (2003) Am J Clin Nut , vol.78 , pp. 1135-1140
    • Esposito, K.1    Nappo, F.2    Giugliano, F.3    Di Palo, C.4    Ciotola, M.5    Barbieri, M.6
  • 58
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-53.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.