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Volumn 21, Issue 2, 2005, Pages 199-209

Genetic aspects of diabetes and its cardiovascular complications: Contribution of genetics to risk assessment and clinical management

Author keywords

Cardiovascular diseases; Genetics; Metabolic syndrome; Risk factors; Type II diabetes mellitus

Indexed keywords

ADIPONECTIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; ARYLDIALKYLPHOSPHATASE; ATRIAL NATRIURETIC FACTOR; BRADYKININ; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; FATTY ACID; FATTY ACID BINDING PROTEIN; GELATINASE B; GENE PRODUCT; GLUCAGON RECEPTOR; GLUCOSE TRANSPORTER; GLYCEROL; GLYCOGEN SYNTHASE; GLYCOPROTEIN; INOSITOL TRISPHOSPHATE 3 KINASE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LEPTIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; RESISTIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 17044424910     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (148)
  • 1
    • 0031445908 scopus 로고    scopus 로고
    • The rising global burden of diabetes and its complications: Estimates and projections to the year 2010
    • Amos AF, McCarty DJ, Zimmet P. The rising global burden of diabetes and its complications: Estimates and projections to the year 2010. Diabet Med 1997;14(Suppl 5):S1-85.
    • (1997) Diabet. Med. , vol.14 , Issue.SUPPL. 5
    • Amos, A.F.1    McCarty, D.J.2    Zimmet, P.3
  • 2
    • 0031897103 scopus 로고    scopus 로고
    • Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults
    • The Third National Health and Nutrition Examination Survey, 1988-1994
    • Harris MI, Flegal KM, Cowie CC, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 1998;21:518-24.
    • (1998) Diabetes Care , vol.21 , pp. 518-524
    • Harris, M.I.1    Flegal, K.M.2    Cowie, C.C.3
  • 3
    • 0033533596 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease: A statement for healthcare professionals from the American Heart Association
    • Grundy SM, Benjamin IJ, Burke GL, et al. Diabetes and cardiovascular disease: A statement for healthcare professionals from the American Heart Association. Circulation 1999;100:1134-46.
    • (1999) Circulation , vol.100 , pp. 1134-1146
    • Grundy, S.M.1    Benjamin, I.J.2    Burke, G.L.3
  • 4
    • 0033911688 scopus 로고    scopus 로고
    • Impact of diabetes on coronary artery disease in women and men: A meta-analysis of prospective studies
    • Lee WL, Cheung AM, Cape D, Zinman B. Impact of diabetes on coronary artery disease in women and men: A meta-analysis of prospective studies. Diabetes Care 2000;23:962-8.
    • (2000) Diabetes Care , vol.23 , pp. 962-968
    • Lee, W.L.1    Cheung, A.M.2    Cape, D.3    Zinman, B.4
  • 5
    • 0033553188 scopus 로고    scopus 로고
    • Diabetes and decline in heart disease mortality in US adults
    • Gu K, Cowie CC, Harris MI. Diabetes and decline in heart disease mortality in US adults. JAMA 1999;281:1291-7.
    • (1999) JAMA , vol.281 , pp. 1291-1297
    • Gu, K.1    Cowie, C.C.2    Harris, M.I.3
  • 6
    • 0035897696 scopus 로고    scopus 로고
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP)
    • Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486-97.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 8
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15:539-53.
    • (1998) Diabet. Med. , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 9
    • 0141526209 scopus 로고    scopus 로고
    • Lipid disorders in diabetes
    • Pickup JC, Williams G, eds. 3rd edn. Oxford: Blackwell Publishing
    • Poirier F, Després JP. Lipid disorders in diabetes. In: Pickup JC, Williams G, eds. Textbook of Diabetes, 3rd edn. Oxford: Blackwell Publishing, 2002:54.1-54.21.
    • (2002) Textbook of Diabetes
    • Poirier, F.1    Després, J.P.2
  • 11
    • 0033069767 scopus 로고    scopus 로고
    • Guidelines Subcommittee
    • World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
    • World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. Guidelines Subcommittee. J Hypertens 1999;17:151-83.
    • (1999) J. Hypertens. , vol.17 , pp. 151-183
  • 12
    • 0036891935 scopus 로고    scopus 로고
    • Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study
    • Laaksonen DE, Lakka HM, Niskanen LK, Kaplan GA, Salonen JT, Lakka TA. Metabolic syndrome and development of diabetes mellitus: Application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. Am J Epidemiol 2002;156:1070-7.
    • (2002) Am. J. Epidemiol. , vol.156 , pp. 1070-1077
    • Laaksonen, D.E.1    Lakka, H.M.2    Niskanen, L.K.3    Kaplan, G.A.4    Salonen, J.T.5    Lakka, T.A.6
  • 13
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 14
    • 0032474427 scopus 로고    scopus 로고
    • American Heart Association call to action: Obesity as a major risk factor for coronary heart disease
    • AHA Nutrition Committee
    • Eckel RH, Krauss RM; AHA Nutrition Committee. American Heart Association call to action: Obesity as a major risk factor for coronary heart disease. Circulation 1998;97:2099-100.
    • (1998) Circulation , vol.97 , pp. 2099-2100
    • Eckel, R.H.1    Krauss, R.M.2
  • 15
    • 0032915845 scopus 로고    scopus 로고
    • Microalbuminuria as a predictive factor for cardiovascular events
    • Luft FC, Agrawal B. Microalbuminuria as a predictive factor for cardiovascular events. J Cardiovasc Pharmacol 1999;33(Suppl 1):S11-5.
    • (1999) J. Cardiovasc. Pharmacol. , vol.33 , Issue.SUPPL. 1
    • Luft, F.C.1    Agrawal, B.2
  • 16
    • 0027154856 scopus 로고
    • The insulin resistance-dyslipidemia syndrome: The most prevalent cause of coronary artery disease?
    • Després JP. The insulin resistance-dyslipidemia syndrome: The most prevalent cause of coronary artery disease? CMAJ 1993;148:1339-40.
    • (1993) CMAJ , vol.148 , pp. 1339-1340
    • Després, J.P.1
  • 17
    • 0030713021 scopus 로고    scopus 로고
    • The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure
    • (Erratum in 1998;158:573)
    • The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 1997;157:2413-46. (Erratum in 1998;158:573)
    • (1997) Arch. Intern. Med. , vol.157 , pp. 2413-2446
  • 18
    • 0034837376 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality associated with the metabolic syndrome
    • Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001;24:683-9.
    • (2001) Diabetes Care , vol.24 , pp. 683-689
    • Isomaa, B.1    Almgren, P.2    Tuomi, T.3
  • 19
    • 0035941940 scopus 로고    scopus 로고
    • Treatment of obesity: Need to focus on high risk abdominally obese patients
    • Després JP, Lemieux I, Prud'homme D. Treatment of obesity: Need to focus on high risk abdominally obese patients. BMJ 2001;322:716-20.
    • (2001) BMJ , vol.322 , pp. 716-720
    • Després, J.P.1    Lemieux, I.2    Prud'homme, D.3
  • 20
    • 0032923669 scopus 로고    scopus 로고
    • C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992
    • Koenig W, Sund M, Frohlich M, et al. C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992. Circulation 1999;99:237-42.
    • (1999) Circulation , vol.99 , pp. 237-242
    • Koenig, W.1    Sund, M.2    Frohlich, M.3
  • 21
    • 0032790922 scopus 로고    scopus 로고
    • Associations of C-reactive protein with measures of obesity, insulin resistance and subclinical atherosclerosis in healthy, middle-aged women
    • Hak AE, Stehouwer CD, Bots ML, et al. Associations of C-reactive protein with measures of obesity, insulin resistance and subclinical atherosclerosis in healthy, middle-aged women. Arterioscler Thromb Vasc Biol 1999;19:1986-91.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 1986-1991
    • Hak, A.E.1    Stehouwer, C.D.2    Bots, M.L.3
  • 22
    • 0037022237 scopus 로고    scopus 로고
    • Weight loss reduces C-reactive protein levels in obese postmenopausal women
    • Tchernof A, Nolan A, Sites CK, Ades PA, Poehlman ET Weight loss reduces C-reactive protein levels in obese postmenopausal women. Circulation 2002;105:564-9.
    • (2002) Circulation , vol.105 , pp. 564-569
    • Tchernof, A.1    Nolan, A.2    Sites, C.K.3    Ades, P.A.4    Poehlman, E.T.5
  • 23
    • 0035717514 scopus 로고    scopus 로고
    • Elevated C-reactive protein: Another component of the atherothrombotic profile of abdominal obesity
    • Lemieux I, Pascot A, Prud'homme D, et al. Elevated C-reactive protein: Another component of the atherothrombotic profile of abdominal obesity. Arterioscler Thromb Vasc Biol 2001;21:961-7.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 961-967
    • Lemieux, I.1    Pascot, A.2    Prud'homme, D.3
  • 24
    • 0034097892 scopus 로고    scopus 로고
    • Triglycerides, apo C3 and Lp B: C3 and cardiovascular risk in type II diabetes
    • Gervaise N, Garrigue MA, Lasfargues G, Lecomte P. Triglycerides, apo C3 and Lp B: C3 and cardiovascular risk in type II diabetes. Diabetologia 2000;43:703-8.
    • (2000) Diabetologia , vol.43 , pp. 703-708
    • Gervaise, N.1    Garrigue, M.A.2    Lasfargues, G.3    Lecomte, P.4
  • 25
    • 0025886577 scopus 로고
    • Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease
    • Genest JJ Jr, McNamara JR, Upson B, et al. Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease. Arterioscler Thromb 1991;11:1129-36.
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 1129-1136
    • Genest Jr., J.J.1    McNamara, J.R.2    Upson, B.3
  • 26
    • 0024359041 scopus 로고
    • Hemostatic variables in Japanese and Caucasian men. Plasma fibrinogen, factor VIIc, factor VIIIc, and von Willebrand factor and their relations to cardiovascular disease risk factors
    • Iso H, Folsom AR, Wu KK, et al. Hemostatic variables in Japanese and Caucasian men. Plasma fibrinogen, factor VIIc, factor VIIIc, and von Willebrand factor and their relations to cardiovascular disease risk factors. Am J Epidemiol 1989;130:925-34.
    • (1989) Am. J. Epidemiol. , vol.130 , pp. 925-934
    • Iso, H.1    Folsom, A.R.2    Wu, K.K.3
  • 28
    • 0028933137 scopus 로고
    • Apolipoprotein E polymorphism as a risk factor for vascular disease in diabetic patients
    • Boemi M, Sirolla C, Amadio L, Fumelli P, Pometta D, James RW. Apolipoprotein E polymorphism as a risk factor for vascular disease in diabetic patients. Diabetes Care 1995;18:504-8.
    • (1995) Diabetes Care , vol.18 , pp. 504-508
    • Boemi, M.1    Sirolla, C.2    Amadio, L.3    Fumelli, P.4    Pometta, D.5    James, R.W.6
  • 30
    • 0037154285 scopus 로고    scopus 로고
    • Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Munster (PROCAM) study
    • Assmann G, Cullen P, Schulte H. Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Munster (PROCAM) study. Circulation 2002;105:310-5.
    • (2002) Circulation , vol.105 , pp. 310-315
    • Assmann, G.1    Cullen, P.2    Schulte, H.3
  • 31
    • 0037160969 scopus 로고    scopus 로고
    • Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
    • LIFE Study Group
    • Lindholm LH, Ibsen H, Dahlof B, et al; LIFE Study Group. Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol. Lancet 2002;359:1004-10.
    • (2002) Lancet , vol.359 , pp. 1004-1010
    • Lindholm, L.H.1    Ibsen, H.2    Dahlof, B.3
  • 32
    • 0032513878 scopus 로고    scopus 로고
    • Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial
    • HOT Study Group
    • Hansson L, Zanchetti A, Carruthers SG, et al; HOT Study Group. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 1998;351:1755-62.
    • (1998) Lancet , vol.351 , pp. 1755-1762
    • Hansson, L.1    Zanchetti, A.2    Carruthers, S.G.3
  • 35
    • 1842294593 scopus 로고    scopus 로고
    • Genetic and nongenetic determinants of salt sensitivity and blood pressure
    • Cowley AW Jr. Genetic and nongenetic determinants of salt sensitivity and blood pressure. Am J Clin Nutr 1997;65(2 Suppl):587S-93S.
    • (1997) Am. J. Clin. Nutr. , vol.65 , Issue.2 SUPPL.
    • Cowley Jr., A.W.1
  • 36
    • 0035725057 scopus 로고    scopus 로고
    • Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms
    • Poch E, Gonzalez D, Giner V, Bragulat E, Coca A, de La Sierra A. Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms. Hypertension 2001;38:1204-9.
    • (2001) Hypertension , vol.38 , pp. 1204-1209
    • Poch, E.1    Gonzalez, D.2    Giner, V.3    Bragulat, E.4    Coca, A.5    de La Sierra, A.6
  • 37
    • 0034926855 scopus 로고    scopus 로고
    • Endothelial function and coronary artery disease
    • Kinlay S, Libby P, Ganz P. Endothelial function and coronary artery disease. Curr Opin Lipidol 2001;12:383-9.
    • (2001) Curr. Opin. Lipidol. , vol.12 , pp. 383-389
    • Kinlay, S.1    Libby, P.2    Ganz, P.3
  • 38
    • 0034166728 scopus 로고    scopus 로고
    • Hypertension-induced organ damage in African Americans: Transforming growth factor-beta(1) excess as a mechanism for increased prevalence
    • August P, Leventhal B, Suthanthiran M. Hypertension-induced organ damage in African Americans: Transforming growth factor-beta(1) excess as a mechanism for increased prevalence. Curr Hypertens Rep 2000;2:184-91.
    • (2000) Curr. Hypertens. Rep. , vol.2 , pp. 184-191
    • August, P.1    Leventhal, B.2    Suthanthiran, M.3
  • 39
    • 0035924359 scopus 로고    scopus 로고
    • Endothelin-1 synthesis reduced by red wine
    • Corder R, Douthwaite JA, Lees DM, et al. Endothelin-1 synthesis reduced by red wine. Nature 2001;414:863-4.
    • (2001) Nature , vol.414 , pp. 863-864
    • Corder, R.1    Douthwaite, J.A.2    Lees, D.M.3
  • 40
    • 0036177622 scopus 로고    scopus 로고
    • Salt intake, endothelial dysfunction, and salt-sensitive hypertension
    • Bragulat E, de la Sierra A. Salt intake, endothelial dysfunction, and salt-sensitive hypertension. J Clin Hypertens 2002;4:41-6.
    • (2002) J. Clin. Hypertens. , vol.4 , pp. 41-46
    • Bragulat, E.1    de la Sierra, A.2
  • 41
    • 0032704074 scopus 로고    scopus 로고
    • Endothelial dysfunction in type 2 diabetic subjects with and without microalbuminuria
    • Meeking DR, Cummings MH, Thorne S, et al. Endothelial dysfunction in type 2 diabetic subjects with and without microalbuminuria. Diabet Med 1999;16:841-7.
    • (1999) Diabet. Med. , vol.16 , pp. 841-847
    • Meeking, D.R.1    Cummings, M.H.2    Thorne, S.3
  • 42
    • 0034007216 scopus 로고    scopus 로고
    • Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes
    • Neugebauer S, Baba T, Watanabe T Association of the nitric oxide synthase gene polymorphism with an increased risk for progression to diabetic nephropathy in type 2 diabetes. Diabetes 2000;49:500-3.
    • (2000) Diabetes , vol.49 , pp. 500-503
    • Neugebauer, S.1    Baba, T.2    Watanabe, T.3
  • 43
    • 0033826632 scopus 로고    scopus 로고
    • Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with elevated blood pressure in type 2 diabetic patients with coronary heart disease
    • Pulkkinen A, Viitanen L, Kareinen A, Lehto S, Vauhkonen I, Laakso M. Intron 4 polymorphism of the endothelial nitric oxide synthase gene is associated with elevated blood pressure in type 2 diabetic patients with coronary heart disease. J Mol Med 2000;78:372-9.
    • (2000) J. Mol. Med. , vol.78 , pp. 372-379
    • Pulkkinen, A.1    Viitanen, L.2    Kareinen, A.3    Lehto, S.4    Vauhkonen, I.5    Laakso, M.6
  • 44
    • 12444250189 scopus 로고    scopus 로고
    • The inherited basis of blood pressure variation and hypertension
    • Scriver CR, Beaudet AL, Sly WS, et al, eds. New York: McGraw-Hill
    • Gharavi ALR. The inherited basis of blood pressure variation and hypertension. In: Scriver CR, Beaudet AL, Sly WS, et al, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2001:5399-413.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 5399-5413
    • Gharavi, A.L.R.1
  • 45
    • 0033862078 scopus 로고    scopus 로고
    • Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians
    • Pausova Z, Deslauriers B, Gaudet D, et al. Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians. Hypertension 2000;36:14-9.
    • (2000) Hypertension , vol.36 , pp. 14-19
    • Pausova, Z.1    Deslauriers, B.2    Gaudet, D.3
  • 46
    • 0036119189 scopus 로고    scopus 로고
    • The TNF alpha/G-308A polymorphism influences insulin sensitivity in offspring of patients with coronary heart disease: The European Atherosclerosis Research Study II
    • Nicaud V, Raoux S, Poirier O, Cambien F, O'Reilly DS, Tiret L. The TNF alpha/G-308A polymorphism influences insulin sensitivity in offspring of patients with coronary heart disease: The European Atherosclerosis Research Study II. Atherosclerosis 2002;161:317-25.
    • (2002) Atherosclerosis , vol.161 , pp. 317-325
    • Nicaud, V.1    Raoux, S.2    Poirier, O.3    Cambien, F.4    O'Reilly, D.S.5    Tiret, L.6
  • 47
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. (Erratum in 1999;354:602)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-53. (Erratum in 1999;354:602)
    • (1998) Lancet , vol.352 , pp. 837-853
  • 48
    • 0037061867 scopus 로고    scopus 로고
    • Clinical practice. Nephropathy in patients with type 2 diabetes
    • Remuzzi G, Schieppati A, Ruggenenti P. Clinical practice. Nephropathy in patients with type 2 diabetes. N Engl J Med 2002;346:1145-51.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1145-1151
    • Remuzzi, G.1    Schieppati, A.2    Ruggenenti, P.3
  • 49
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-60.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 50
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861-9.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3
  • 52
    • 0034786032 scopus 로고    scopus 로고
    • Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy
    • Maeda S, Haneda M, Guo B, et al. Dinucleotide repeat polymorphism of matrix metalloproteinase-9 gene is associated with diabetic nephropathy. Kidney Int 2001;60:1428-34.
    • (2001) Kidney Int. , vol.60 , pp. 1428-1434
    • Maeda, S.1    Haneda, M.2    Guo, B.3
  • 54
    • 0035061134 scopus 로고    scopus 로고
    • Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension
    • Chaves FJ, Pascual JM, Rovira E, Armengod ME, Redon J. Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension. Am J Hypertens 2001;14:364-70.
    • (2001) Am. J. Hypertens. , vol.14 , pp. 364-370
    • Chaves, F.J.1    Pascual, J.M.2    Rovira, E.3    Armengod, M.E.4    Redon, J.5
  • 56
    • 0033014947 scopus 로고    scopus 로고
    • Association between AGT T235 variant and microalbuminuria in Canadian Oji-Cree with type 2 diabetes mellitus
    • Hegele RA, Harris SB, Hanley AJ, Zinman B. Association between AGT T235 variant and microalbuminuria in Canadian Oji-Cree with type 2 diabetes mellitus. Clin Biochem 1999;32:201-5.
    • (1999) Clin. Biochem. , vol.32 , pp. 201-205
    • Hegele, R.A.1    Harris, S.B.2    Hanley, A.J.3    Zinman, B.4
  • 57
    • 0033625681 scopus 로고    scopus 로고
    • G(-699)/C polymorphism in the bradykinin-1 receptor gene in patients with renal failure
    • Knigge H, Bluthner M, Bruntgens A, Sator H, Ritz E. G(-699)/C polymorphism in the bradykinin-1 receptor gene in patients with renal failure. Nephrol Dial Transplant 2000;15:586-8.
    • (2000) Nephrol. Dial. Transplant. , vol.15 , pp. 586-588
    • Knigge, H.1    Bluthner, M.2    Bruntgens, A.3    Sator, H.4    Ritz, E.5
  • 58
    • 0034068916 scopus 로고    scopus 로고
    • Influence of insertion/deletion polymorphism in the ACE-I gene on the progression of diabetic glomerulopathy in type 1 diabetic patients with microalbuminuria
    • Rudberg S, Rasmussen LM, Bangstad HJ, Osterby R. Influence of insertion/deletion polymorphism in the ACE-I gene on the progression of diabetic glomerulopathy in type 1 diabetic patients with microalbuminuria. Diabetes Care 2000;23:544-8.
    • (2000) Diabetes Care , vol.23 , pp. 544-548
    • Rudberg, S.1    Rasmussen, L.M.2    Bangstad, H.J.3    Osterby, R.4
  • 59
    • 0003835753 scopus 로고    scopus 로고
    • Counting the cost: The real impact of non-insulin-dependent diabetes
    • British Diabetic Association. London: Kings Fund Policy Institute
    • British Diabetic Association. Counting the cost: The real impact of non-insulin-dependent diabetes. London: Kings Fund Policy Institute, 1996.
    • (1996)
  • 60
    • 0030935652 scopus 로고    scopus 로고
    • Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance
    • The Da Qing IGT and Diabetes Study
    • Pan XR, Li GW, Hu YH, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 1997;20:537-44.
    • (1997) Diabetes Care , vol.20 , pp. 537-544
    • Pan, X.R.1    Li, G.W.2    Hu, Y.H.3
  • 61
    • 0025750835 scopus 로고
    • Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study
    • Eriksson KF, Lindgarde F. Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study. Diabetologia 1991;34:891-8.
    • (1991) Diabetologia , vol.34 , pp. 891-898
    • Eriksson, K.F.1    Lindgarde, F.2
  • 62
    • 0035799806 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    • Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001;344:1343-50.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1343-1350
    • Tuomilehto, J.1    Lindstrom, J.2    Eriksson, J.G.3
  • 63
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393-403.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 64
    • 0037661714 scopus 로고    scopus 로고
    • The heart and obesity
    • Fuster V, Alexander RW, King S, O'Rourke RA, Roberts R, Wellens HJJ, eds. 10 edn. New York: McGraw-Hill
    • Poirier P, Eckel RH. The heart and obesity. In: Fuster V, Alexander RW, King S, O'Rourke RA, Roberts R, Wellens HJJ, eds. Hurst's The Heart, 10 edn. New York: McGraw-Hill, 2000:2289-303.
    • (2000) Hurst's The Heart , pp. 2289-2303
    • Poirier, P.1    Eckel, R.H.2
  • 66
    • 0005943357 scopus 로고    scopus 로고
    • Diabetes mellitus
    • Scriver CR, Beaudet AL, Sly WS, et al, eds. New York: McGraw-Hill
    • Taylor SI. Diabetes mellitus. In: Scriver CR, Beaudet AL, Sly WS, et al, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2001:1433-69.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 1433-1469
    • Taylor, S.I.1
  • 67
    • 0027953703 scopus 로고
    • Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes
    • Kahn CR. Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 1994;43:1066-84.
    • (1994) Diabetes , vol.43 , pp. 1066-1084
    • Kahn, C.R.1
  • 68
    • 0031773333 scopus 로고    scopus 로고
    • Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians
    • Hani EH, Boutin P, Durand E, et al. Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia 1998;41:1511-5.
    • (1998) Diabetologia , vol.41 , pp. 1511-1515
    • Hani, E.H.1    Boutin, P.2    Durand, E.3
  • 69
    • 0037464795 scopus 로고    scopus 로고
    • A new subtype of amosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1
    • Huopio H, Otonkoski T, Vauhkonen I, Reimann F, Ashcroft FM, Laakso M. A new subtype of amosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1. Lancet 2003;361:301-7.
    • (2003) Lancet , vol.361 , pp. 301-307
    • Huopio, H.1    Otonkoski, T.2    Vauhkonen, I.3    Reimann, F.4    Ashcroft, F.M.5    Laakso, M.6
  • 70
    • 0036134187 scopus 로고    scopus 로고
    • Resistin and obesity-associated insulin resistance
    • Steppan CM, Lazar MA. Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 2002;13:18-23.
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 18-23
    • Steppan, C.M.1    Lazar, M.A.2
  • 71
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-53.
    • (2001) Nat. Med. , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 72
    • 0036314156 scopus 로고    scopus 로고
    • Human resistin gene, obesity, and type 2 diabetes: Mutation analysis and population study
    • Sentinelli F, Romeo S, Arca M, et al. Human resistin gene, obesity, and type 2 diabetes: Mutation analysis and population study. Diabetes 2002;51:860-2.
    • (2002) Diabetes , vol.51 , pp. 860-862
    • Sentinelli, F.1    Romeo, S.2    Arca, M.3
  • 73
    • 0035522298 scopus 로고    scopus 로고
    • Resistin, obesity and insulin resistance - The emerging role of the adipocyte as an endocrine organ
    • Shuldiner AR, Yang R, Gong DW. Resistin, obesity and insulin resistance - the emerging role of the adipocyte as an endocrine organ. N Engl J Med 2001;345:1345-6.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 1345-1346
    • Shuldiner, A.R.1    Yang, R.2    Gong, D.W.3
  • 74
    • 0036710513 scopus 로고    scopus 로고
    • An adipocentric view of signaling and intracellular trafficking
    • Mora S, Pessin JE. An adipocentric view of signaling and intracellular trafficking. Diabetes Metab Res Rev 2002;18:345-56.
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. 345-356
    • Mora, S.1    Pessin, J.E.2
  • 75
    • 0031775895 scopus 로고    scopus 로고
    • Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk
    • Leyva F, Godsland IF, Ghatei M, et al. Hyperleptinemia as a component of a metabolic syndrome of cardiovascular risk. Arterioscler Thromb Vasc Biol 1998;18:928-33.
    • (1998) Arterioscler. Thromb. Vasc. Biol. , vol.18 , pp. 928-933
    • Leyva, F.1    Godsland, I.F.2    Ghatei, M.3
  • 76
    • 0030895726 scopus 로고    scopus 로고
    • Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: Evidence for a P13-kinase mediated effect
    • Berti L, Kellerer M, Capp E, Haring HU. Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: Evidence for a P13-kinase mediated effect. Diabetologia 1997;40:606-9.
    • (1997) Diabetologia , vol.40 , pp. 606-609
    • Berti, L.1    Kellerer, M.2    Capp, E.3    Haring, H.U.4
  • 77
    • 0040381066 scopus 로고    scopus 로고
    • Leptin impairs metabolic actions of insulin in isolated rat adipocytes
    • Muller G, Ertl J, Gerl M, Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 1997;272:10585-93.
    • (1997) J. Biol. Chem. , vol.272 , pp. 10585-10593
    • Muller, G.1    Ertl, J.2    Gerl, M.3    Preibisch, G.4
  • 78
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • Horikawa Y, Oda N, Cox NJ, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 2000;26:163-75.
    • (2000) Nat. Genet. , vol.26 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.J.3
  • 79
    • 0028299585 scopus 로고
    • Waist circumference and abdominal sagittal diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women
    • Pouliot MC, Després JP, Lemieux S, et al. Waist circumference and abdominal sagittal diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol 1994;73:460-8.
    • (1994) Am. J. Cardiol. , vol.73 , pp. 460-468
    • Pouliot, M.C.1    Després, J.P.2    Lemieux, S.3
  • 80
    • 0036558732 scopus 로고    scopus 로고
    • Abdominal obesity is associated with increased risk of acute coronary events in men
    • Lakka HM, Lakka TA, Tuomilehto J, Salonen JT. Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J 2002;23:706-13.
    • (2002) Eur. Heart J. , vol.23 , pp. 706-713
    • Lakka, H.M.1    Lakka, T.A.2    Tuomilehto, J.3    Salonen, J.T.4
  • 81
    • 0032881725 scopus 로고    scopus 로고
    • The small, dense LDL phenotype and the risk of coronary heart disease: Epidemiology, patho-physiology and therapeutic aspects
    • Lamarche B, Lemieux I, Després JP. The small, dense LDL phenotype and the risk of coronary heart disease: Epidemiology, patho-physiology and therapeutic aspects. Diabetes Metab 1999;25:199-211.
    • (1999) Diabetes Metab. , vol.25 , pp. 199-211
    • Lamarche, B.1    Lemieux, I.2    Després, J.P.3
  • 82
    • 0032468846 scopus 로고    scopus 로고
    • Visceral obesity and the risk of ischaemic heart disease: Insights from the Quebec Cardiovascular Study
    • Lamarche B, Lemieux S, Dagenais GR, Després JP. Visceral obesity and the risk of ischaemic heart disease: Insights from the Quebec Cardiovascular Study. Growth Horm IGF Res 1998;8(Suppl B):1-8.
    • (1998) Growth Horm. IGF Res. , vol.8 , Issue.SUPPL. B , pp. 1-8
    • Lamarche, B.1    Lemieux, S.2    Dagenais, G.R.3    Després, J.P.4
  • 84
    • 0034534530 scopus 로고    scopus 로고
    • Genetics of human obesity: Results from genetic epidemiology studies
    • Pérusse L. Genetics of human obesity: Results from genetic epidemiology studies. Ann Endocrinol 2000;61(Suppl 6):24-30.
    • (2000) Ann. Endocrinol. , vol.61 , Issue.SUPPL. 6 , pp. 24-30
    • Pérusse, L.1
  • 85
    • 0032497945 scopus 로고    scopus 로고
    • The Care Investigators. Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: Subgroup analyses in the cholesterol and recurrent events (CARE) trial
    • Goldberg RB, Mellies MJ, Sacks FM, et al; The Care Investigators. Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: Subgroup analyses in the cholesterol and recurrent events (CARE) trial. Circulation 1998;98:2513-9.
    • (1998) Circulation , vol.98 , pp. 2513-2519
    • Goldberg, R.B.1    Mellies, M.J.2    Sacks, F.M.3
  • 86
    • 1842326783 scopus 로고    scopus 로고
    • Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)
    • Pyorala K, Pedersen TR, Kjekshus J, Faergeman O, Olsson AG, Thorgeirsson G. Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S). Diabetes Care 1997;20:614-20.
    • (1997) Diabetes Care , vol.20 , pp. 614-620
    • Pyorala, K.1    Pedersen, T.R.2    Kjekshus, J.3    Faergeman, O.4    Olsson, A.G.5    Thorgeirsson, G.6
  • 87
    • 0033611310 scopus 로고    scopus 로고
    • Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: Subgroup analyses in the Scandinavian Simvastatin Survival Study
    • Haffner SM, Alexander CM, Cook TJ, et al. Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: Subgroup analyses in the Scandinavian Simvastatin Survival Study. Arch Intern Med 1999;159:2661-7.
    • (1999) Arch. Intern. Med. , vol.159 , pp. 2661-2667
    • Haffner, S.M.1    Alexander, C.M.2    Cook, T.J.3
  • 88
    • 77956915141 scopus 로고
    • Lipoprotein lipase and hepatic lipases
    • Jackson RL, Boyer P, eds. New York: Academic Press
    • Jackson RL. Lipoprotein lipase and hepatic lipases. In: Jackson RL, Boyer P, eds. The enzymes. New York: Academic Press, 1983:141-81.
    • (1983) The Enzymes , pp. 141-181
    • Jackson, R.L.1
  • 90
    • 0034907585 scopus 로고    scopus 로고
    • Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Quebec Family Study
    • Ukkola O, Garenc C, Pérusse L, et al. Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Quebec Family Study. Atherosclerosis 2001;158:199-206.
    • (2001) Atherosclerosis , vol.158 , pp. 199-206
    • Ukkola, O.1    Garenc, C.2    Pérusse, L.3
  • 91
    • 0029036594 scopus 로고
    • The lipoprotein lipase HindIII polymorphism modulates plasma triglyceride levels in visceral obesity
    • Vohl MC, Lamarche B, Moorjani S, et al. The lipoprotein lipase HindIII polymorphism modulates plasma triglyceride levels in visceral obesity. Arterioscler Thromb Vasc Biol 1995;15:714-20.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 714-720
    • Vohl, M.C.1    Lamarche, B.2    Moorjani, S.3
  • 93
    • 0031470430 scopus 로고    scopus 로고
    • Common variation in the lipoprotein lipase gene: Effects on plasma lipids and risk of atherosclerosis
    • Fisher RM, Humphries SE, Talmud PJ. Common variation in the lipoprotein lipase gene: Effects on plasma lipids and risk of atherosclerosis. Atherosclerosis 1997;135:145-59.
    • (1997) Atherosclerosis , vol.135 , pp. 145-159
    • Fisher, R.M.1    Humphries, S.E.2    Talmud, P.J.3
  • 94
    • 0033536024 scopus 로고    scopus 로고
    • Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis
    • Wittrup HH, Tybjaerg-Hansen A, Nordestgaard BG. Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis. Circulation 1999;99:2901-7.
    • (1999) Circulation , vol.99 , pp. 2901-2907
    • Wittrup, H.H.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 95
    • 0032502260 scopus 로고    scopus 로고
    • Relationships of abdominal obesity and hyperinsulinemia to angiographically assessed coronary artery disease in men with known mutations in the LDL receptor gene
    • Gaudet D, Vohl MC, Perron P, et al. Relationships of abdominal obesity and hyperinsulinemia to angiographically assessed coronary artery disease in men with known mutations in the LDL receptor gene. Circulation 1998;97:871-7.
    • (1998) Circulation , vol.97 , pp. 871-877
    • Gaudet, D.1    Vohl, M.C.2    Perron, P.3
  • 96
    • 15144339953 scopus 로고    scopus 로고
    • Hyperinsulinemia and abdominal obesity affect the expression of hypertriglyceridemia in heterozygous familial lipoprotein lipase deficiency
    • Julien P, Vohl MC, Gaudet D, et al. Hyperinsulinemia and abdominal obesity affect the expression of hypertriglyceridemia in heterozygous familial lipoprotein lipase deficiency. Diabetes 1997;46:2063-8.
    • (1997) Diabetes , vol.46 , pp. 2063-2068
    • Julien, P.1    Vohl, M.C.2    Gaudet, D.3
  • 97
    • 0346035910 scopus 로고    scopus 로고
    • Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men
    • St-Pierre J, Miller-Felix I, Paradis ME, et al. Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men. Mol Genet Metab 2003;78:31-6.
    • (2003) Mol. Genet. Metab. , vol.78 , pp. 31-36
    • St-Pierre, J.1    Miller-Felix, I.2    Paradis, M.E.3
  • 98
    • 0036180958 scopus 로고    scopus 로고
    • Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men
    • St-Pierre J, Lemieux I, Miller-Felix I, et al. Visceral obesity and hyperinsulinemia modulate the impact of the microsomal triglyceride transfer protein -493G/T polymorphism on plasma lipoprotein levels in men. Atherosclerosis 2002;160:317-24.
    • (2002) Atherosclerosis , vol.160 , pp. 317-324
    • St-Pierre, J.1    Lemieux, I.2    Miller-Felix, I.3
  • 99
    • 0024996141 scopus 로고
    • Plasma high density lipoproteins. Metabolism and relationship to atherogenesis
    • Tall AR. Plasma high density lipoproteins. Metabolism and relationship to atherogenesis. J Clin Invest 1990;86:379-84.
    • (1990) J. Clin. Invest. , vol.86 , pp. 379-384
    • Tall, A.R.1
  • 100
    • 0030045883 scopus 로고    scopus 로고
    • High density lipoproteins and coronary heart disease
    • Barter PJ, Rye KA. High density lipoproteins and coronary heart disease. Atherosclerosis 1996;121:1-12.
    • (1996) Atherosclerosis , vol.121 , pp. 1-12
    • Barter, P.J.1    Rye, K.A.2
  • 101
    • 0028156929 scopus 로고
    • Apolipoproteins and ischaemic heart disease: Implications for screening
    • Wald NJ, Law M, Watt HC, et al. Apolipoproteins and ischaemic heart disease: Implications for screening. Lancet 1994;343:75-9.
    • (1994) Lancet , vol.343 , pp. 75-79
    • Wald, N.J.1    Law, M.2    Watt, H.C.3
  • 102
    • 0033304602 scopus 로고    scopus 로고
    • Sex-dependent association of a genetic polymorphism of cholesteryl ester transfer protein with high-density lipoprotein cholesterol and macrovascular pathology in type II diabetic patients
    • Durlach A, Clavel C, Girard-Globa A, Durlach V. Sex-dependent association of a genetic polymorphism of cholesteryl ester transfer protein with high-density lipoprotein cholesterol and macrovascular pathology in type II diabetic patients. J Clin Endocrinol Metab 1999;84:3656-9.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3656-3659
    • Durlach, A.1    Clavel, C.2    Girard-Globa, A.3    Durlach, V.4
  • 103
    • 0037192323 scopus 로고    scopus 로고
    • Mechanisms of coronary microcirculatory dysfunction in patients with aortic stenosis and angiographically normal coronary arteries
    • Rajappan K, Rimoldi OE, Dutka DP, et al. Mechanisms of coronary microcirculatory dysfunction in patients with aortic stenosis and angiographically normal coronary arteries. Circulation 2002;105:470-6.
    • (2002) Circulation , vol.105 , pp. 470-476
    • Rajappan, K.1    Rimoldi, O.E.2    Dutka, D.P.3
  • 104
    • 0034406481 scopus 로고    scopus 로고
    • PPAR-gamma agonists: Therapeutic role in diabetes, inflammation and cancer
    • Murphy GJ, Holder JC. PPAR-gamma agonists: Therapeutic role in diabetes, inflammation and cancer. Trends Pharmacol Sci 2000;21:469-74.
    • (2000) Trends. Pharmacol. Sci. , vol.21 , pp. 469-474
    • Murphy, G.J.1    Holder, J.C.2
  • 105
    • 0035146287 scopus 로고    scopus 로고
    • Control of vascular cell proliferation and migration by PPAR-gamma: A new approach to the macrovascular complications of diabetes
    • Hsueh WA, Jackson S, Law RE. Control of vascular cell proliferation and migration by PPAR-gamma: A new approach to the macrovascular complications of diabetes. Diabetes Care 2001;24:392-7.
    • (2001) Diabetes Care , vol.24 , pp. 392-397
    • Hsueh, W.A.1    Jackson, S.2    Law, R.E.3
  • 106
    • 0033922356 scopus 로고    scopus 로고
    • Molecular scanning of the human PPARa gene: Association of the L162v mutation with hyperapobetalipoproteinemia
    • Vohl MC, Lepage P, Gaudet D, et al. Molecular scanning of the human PPARa gene: Association of the L162v mutation with hyperapobetalipoproteinemia. J Lipid Res 2000;41:945-52.
    • (2000) J. Lipid Res. , vol.41 , pp. 945-952
    • Vohl, M.C.1    Lepage, P.2    Gaudet, D.3
  • 107
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn JN, Klannemark M, et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 2000;26:76-80.
    • (2000) Nat. Genet. , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 109
    • 0033592123 scopus 로고    scopus 로고
    • Polymorphism in high density lipoprotein paraoxonase gene and risk of acute myocardial infarction in men: Prospective nested case-control study
    • Salonen JT, Malin R, Tuomainen TP, Nyyssonen K, Lakka TA, Lehtimaki T. Polymorphism in high density lipoprotein paraoxonase gene and risk of acute myocardial infarction in men: Prospective nested case-control study. BMJ 1999;319:487-9.
    • (1999) BMJ , vol.319 , pp. 487-489
    • Salonen, J.T.1    Malin, R.2    Tuomainen, T.P.3    Nyyssonen, K.4    Lakka, T.A.5    Lehtimaki, T.6
  • 110
    • 0029788728 scopus 로고    scopus 로고
    • The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns
    • Antikainen M, Murtomaki S, Syvanne M, et al. The Gln-Arg191 polymorphism of the human paraoxonase gene (HUMPONA) is not associated with the risk of coronary artery disease in Finns. J Clin Invest 1996;98:883-5.
    • (1996) J. Clin. Invest. , vol.98 , pp. 883-885
    • Antikainen, M.1    Murtomaki, S.2    Syvanne, M.3
  • 111
    • 0030601629 scopus 로고    scopus 로고
    • The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study
    • Herrmann SM, Blanc H, Poirier O, et al. The Gln/Arg polymorphism of human paraoxonase (PON 192) is not related to myocardial infarction in the ECTIM Study. Atherosclerosis 1996;126:299-303.
    • (1996) Atherosclerosis , vol.126 , pp. 299-303
    • Herrmann, S.M.1    Blanc, H.2    Poirier, O.3
  • 112
    • 0032401550 scopus 로고    scopus 로고
    • The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan
    • Ko YL, Ko YS, Wang SM, et al. The Gln-Arg 191 polymorphism of the human paraoxonase gene is not associated with the risk of coronary artery disease among Chinese in Taiwan. Atherosclerosis 1998;141:259-64.
    • (1998) Atherosclerosis , vol.141 , pp. 259-264
    • Ko, Y.L.1    Ko, Y.S.2    Wang, S.M.3
  • 113
    • 0036122850 scopus 로고    scopus 로고
    • High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients
    • Leviev I, Poirier O, Nicaud V, et al. High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients. Atherosclerosis 2002;161:463-7.
    • (2002) Atherosclerosis , vol.161 , pp. 463-467
    • Leviev, I.1    Poirier, O.2    Nicaud, V.3
  • 115
  • 116
    • 0036725464 scopus 로고    scopus 로고
    • Interaction between free fatty acids and glucose metabolism
    • Boden G. Interaction between free fatty acids and glucose metabolism. Curr Opin Clin Nutr Metab Care 2002;5:545-9.
    • (2002) Curr. Opin. Clin. Nutr. Metab. Care , vol.5 , pp. 545-549
    • Boden, G.1
  • 117
    • 0035715706 scopus 로고    scopus 로고
    • A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians
    • St-Pierre J, Vohl MC, Brisson D, et al. A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians. Mol Genet Metab 2001;72:209-17.
    • (2001) Mol. Genet. Metab. , vol.72 , pp. 209-217
    • St-Pierre, J.1    Vohl, M.C.2    Brisson, D.3
  • 118
    • 0033927458 scopus 로고    scopus 로고
    • Glycerol as a correlate of impaired glucose tolerance: Dissection of a complex system by use of a simple genetic trait
    • Gaudet D, Arsenault S, Pérusse L, et al. Glycerol as a correlate of impaired glucose tolerance: Dissection of a complex system by use of a simple genetic trait. Am J Hum Genet 2000;66:1558-68.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 1558-1568
    • Gaudet, D.1    Arsenault, S.2    Pérusse, L.3
  • 119
    • 0028896925 scopus 로고
    • Cytoplasmic fatty acid-binding proteins: Their structure and genes
    • Veerkamp JH, Maatman RG. Cytoplasmic fatty acid-binding proteins: Their structure and genes. Prog Lipid Res 1995;34:17-52.
    • (1995) Prog. Lipid Res. , vol.34 , pp. 17-52
    • Veerkamp, J.H.1    Maatman, R.G.2
  • 120
    • 0030239495 scopus 로고    scopus 로고
    • Cellular fatty acid-binding proteins: Their function and physiological significance
    • Glatz JF, van der Vusse GJ. Cellular fatty acid-binding proteins: Their function and physiological significance. Prog Lipid Res 1996;35:243-82.
    • (1996) Prog. Lipid Res. , vol.35 , pp. 243-282
    • Glatz, J.F.1    van der Vusse, G.J.2
  • 121
    • 0029993073 scopus 로고    scopus 로고
    • Fatty acid transfer from liver and intestinal fatty acid-binding proteins to membranes occurs by different mechanisms
    • Hsu KT, Storch J. Fatty acid transfer from liver and intestinal fatty acid-binding proteins to membranes occurs by different mechanisms. J Biol Chem 1996;271:13317-23.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13317-13323
    • Hsu, K.T.1    Storch, J.2
  • 122
    • 0027468540 scopus 로고
    • Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians
    • Prochazka M, Lillioja S, Tait JF, et al. Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians. Diabetes 1993;42:514-9.
    • (1993) Diabetes , vol.42 , pp. 514-519
    • Prochazka, M.1    Lillioja, S.2    Tait, J.F.3
  • 123
    • 0028783969 scopus 로고
    • Evidence for linkage of postchallenge insulin levels with intestinal fatty acidbinding protein (FABP2) in Mexican-Americans
    • Mitchell BD, Kammerer CM, O'Connell P, et al. Evidence for linkage of postchallenge insulin levels with intestinal fatty acidbinding protein (FABP2) in Mexican-Americans. Diabetes 1995;44:1046-53.
    • (1995) Diabetes , vol.44 , pp. 1046-1053
    • Mitchell, B.D.1    Kammerer, C.M.2    O'Connell, P.3
  • 124
    • 0035512132 scopus 로고    scopus 로고
    • Effects of the FABP2 A54T mutation on triglyceride metabolism of viscerally obese men
    • Berthier MT, Couillard C, Prud'homme D, et al. Effects of the FABP2 A54T mutation on triglyceride metabolism of viscerally obese men. Obes Res 2001;9:668-75.
    • (2001) Obes. Res. , vol.9 , pp. 668-675
    • Berthier, M.T.1    Couillard, C.2    Prud'homme, D.3
  • 125
    • 0028340212 scopus 로고
    • Polymorphisms of the plasminogen activator inhibitor-1 gene in type 1 and type 2 diabetes, and in patients with diabetic retinopathy
    • Mansfield MW, Stickland MH, Carter AM, Grant PJ, Polymorphisms of the plasminogen activator inhibitor-1 gene in type 1 and type 2 diabetes, and in patients with diabetic retinopathy. Thromb Haemost 1994;71:731-6.
    • (1994) Thromb. Haemost. , vol.71 , pp. 731-736
    • Mansfield, M.W.1    Stickland, M.H.2    Carter, A.M.3    Grant, P.J.4
  • 126
    • 0343893674 scopus 로고    scopus 로고
    • Relationship between plasma plasminogen activator inhibitor 1 and insulin resistance
    • Bastard JP, Pieroni L, Hainque B. Relationship between plasma plasminogen activator inhibitor 1 and insulin resistance. Diabetes Metab Res Rev 2000;16:192-201.
    • (2000) Diabetes Metab. Res. Rev. , vol.16 , pp. 192-201
    • Bastard, J.P.1    Pieroni, L.2    Hainque, B.3
  • 127
    • 0028901713 scopus 로고
    • Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction
    • Eriksson P, Kallin B, van 't Hooft FM, Bavenholm P, Hamsten A. Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction. Proc Natl Acad Sci USA 1995;92:1851-5.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1851-1855
    • Eriksson, P.1    Kallin, B.2    van 't Hooft, F.M.3    Bavenholm, P.4    Hamsten, A.5
  • 128
    • 15844381594 scopus 로고    scopus 로고
    • Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
    • Shimomura I, Funahashi T, Takahashi M, et al. Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity. Nat Med 1996;2:800-3.
    • (1996) Nat. Med. , vol.2 , pp. 800-803
    • Shimomura, I.1    Funahashi, T.2    Takahashi, M.3
  • 129
    • 0030975615 scopus 로고    scopus 로고
    • Production of plasminogen activator inhibitor 1 by human adipose tissue: Possible link between visceral fat accumulation and vascular disease
    • Alessi MC, Peiretti F, Morange P, Henry M, Nalbone G, Juhan-Vague I. Production of plasminogen activator inhibitor 1 by human adipose tissue: Possible link between visceral fat accumulation and vascular disease. Diabetes 1997;46:860-7.
    • (1997) Diabetes , vol.46 , pp. 860-867
    • Alessi, M.C.1    Peiretti, F.2    Morange, P.3    Henry, M.4    Nalbone, G.5    Juhan-Vague, I.6
  • 130
    • 0032449219 scopus 로고    scopus 로고
    • The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity
    • Gerich JE. The genetic basis of type 2 diabetes mellitus: Impaired insulin secretion versus impaired insulin sensitivity. Endocr Rev 1998;19:491-503.
    • (1998) Endocr. Rev. , vol.19 , pp. 491-503
    • Gerich, J.E.1
  • 131
    • 1842526874 scopus 로고    scopus 로고
    • Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification
    • Spec No 1
    • McCarthy MI. Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification. Hum Mol Genet 2004;13 Spec No 1:R33-41.
    • (2004) Hum. Mol. Genet. , vol.13
    • McCarthy, M.I.1
  • 132
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch NJ. Searching for genetic determinants in the new millennium. Nature 2000;405:847-56.
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 134
    • 0002098977 scopus 로고    scopus 로고
    • Disorders of glycerol metabolism
    • Scriver CR, Beaudet AL, Sly WS, et al, eds. New York: McGraw-Hill
    • McCabe ERB. Disorders of glycerol metabolism. In: Scriver CR, Beaudet AL, Sly WS, et al, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2001:2217-37.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 2217-2237
    • McCabe, E.R.B.1
  • 135
    • 17044439706 scopus 로고    scopus 로고
    • La génétique communautaire dans l'étude des traits complexes: L'exemple de la dyslipidémie hypertensive
    • Gaudet D. La génétique communautaire dans l'étude des traits complexes: L'exemple de la dyslipidémie hypertensive. Méd Sci 2000;16:9.
    • (2000) Méd. Sci. , vol.16 , pp. 9
    • Gaudet, D.1
  • 136
    • 17044367619 scopus 로고    scopus 로고
    • La glycérolémie à jeun explique une proportion significative de la variance dans la distribution de la masse corporelle dans des familles hypertendues du Saguenay-Lac-St-Jean
    • St-Pierre J, Brisson D, Larochelle P, Tremblay J, Gaudet D. La glycérolémie à jeun explique une proportion significative de la variance dans la distribution de la masse corporelle dans des familles hypertendues du Saguenay-Lac-St-Jean. Méd Sci 2000;16:21.
    • (2000) Méd. Sci. , vol.16 , pp. 21
    • St-Pierre, J.1    Brisson, D.2    Larochelle, P.3    Tremblay, J.4    Gaudet, D.5
  • 137
    • 0032709868 scopus 로고    scopus 로고
    • Potential role of glycerol leading to rat fructose hypertension
    • Damiano PF, Roson MI, Armando I, et al. Potential role of glycerol leading to rat fructose hypertension. Hypertension 1999;34:1007-11.
    • (1999) Hypertension , vol.34 , pp. 1007-1011
    • Damiano, P.F.1    Roson, M.I.2    Armando, I.3
  • 139
    • 0031032723 scopus 로고    scopus 로고
    • Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study
    • Lamarche B, Tchernof A, Moorjani S, et al. Small, dense lowd-ensity lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Quebec Cardiovascular Study. Circulation 1997;95:69-75.
    • (1997) Circulation , vol.95 , pp. 69-75
    • Lamarche, B.1    Tchernof, A.2    Moorjani, S.3
  • 140
    • 0026741762 scopus 로고
    • Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels
    • Pouliot MC, Després JP, Nadeau A, et al. Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels. Diabetes 1992;41:826-34.
    • (1992) Diabetes , vol.41 , pp. 826-834
    • Pouliot, M.C.1    Després, J.P.2    Nadeau, A.3
  • 141
    • 0029893909 scopus 로고    scopus 로고
    • The dense LDL phenotype. Association with plasma lipoprotein levels, visceral obesity, and hyperinsulinemia in men
    • Tchernof A, Lamarche B, Prud'Homme D, et al. The dense LDL phenotype. Association with plasma lipoprotein levels, visceral obesity, and hyperinsulinemia in men. Diabetes Care 1996;19:629-37.
    • (1996) Diabetes Care , vol.19 , pp. 629-637
    • Tchernof, A.1    Lamarche, B.2    Prud'Homme, D.3
  • 142
    • 0034636818 scopus 로고    scopus 로고
    • Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?
    • Lemieux I, Pascot A, Couillard C, et al. Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men? Circulation 2000;102:179-84.
    • (2000) Circulation , vol.102 , pp. 179-184
    • Lemieux, I.1    Pascot, A.2    Couillard, C.3
  • 143
    • 0036642619 scopus 로고    scopus 로고
    • Contribution of abdominal obesity and hypertriglyceridemia to impaired fasting glucose and coronary artery disease
    • St-Pierre J, Lemieux I, Vohl MC, et al. Contribution of abdominal obesity and hypertriglyceridemia to impaired fasting glucose and coronary artery disease. Am J Cardiol 2002;90:15-8.
    • (2002) Am. J. Cardiol. , vol.90 , pp. 15-18
    • St-Pierre, J.1    Lemieux, I.2    Vohl, M.C.3
  • 144
    • 0036336187 scopus 로고    scopus 로고
    • Prevalence of 'hypertriglyceridemic waist' in men who participated in the Quebec Health Survey: Association with atherogenic and diabetogenic metabolic risk factors
    • Lemieux I, Almeras N, Mauriège P, et al. Prevalence of 'hypertriglyceridemic waist' in men who participated in the Quebec Health Survey: Association with atherogenic and diabetogenic metabolic risk factors. Can J Cardiol 2002;18:725-32.
    • (2002) Can. J. Cardiol. , vol.18 , pp. 725-732
    • Lemieux, I.1    Almeras, N.2    Mauriège, P.3
  • 145
    • 0032562946 scopus 로고    scopus 로고
    • Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease
    • Lamarche B, Tchernof A, Mauriège P, et al. Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease. JAMA 1998;279:1955-61.
    • (1998) JAMA , vol.279 , pp. 1955-1961
    • Lamarche, B.1    Tchernof, A.2    Mauriège, P.3
  • 146
    • 17044420221 scopus 로고    scopus 로고
    • Impact de la mutation N288D du gène de la glycérol kinase sur l'expression phénotypique de l'hypercholestérolémie familiale résultant de la mutation W66G du gène du récepteur des LDL: Un modèle d'interaction génétique associée à la triade métabolique
    • St-Pierre J, Brisson D, Perron P, Després JP, Gaudet D. Impact de la mutation N288D du gène de la glycérol kinase sur l'expression phénotypique de l'hypercholestérolémie familiale résultant de la mutation W66G du gène du récepteur des LDL: Un modèle d'interaction génétique associée à la triade métabolique (hyperapo B, hyperinsulinémie, LDL denses). Méd Sci 2001;17:xx.
    • (2001) Méd. Sci. , vol.17 , pp. 20
    • St-Pierre, J.1    Brisson, D.2    Perron, P.3    Després, J.P.4    Gaudet, D.5
  • 147
    • 0036277206 scopus 로고    scopus 로고
    • Genetic polymorphisms: Importance for response to HMG-CoA reductase inhibitors
    • Maitland-van der Zee AH, Klungel OH, Stricker BH, et al. Genetic polymorphisms: Importance for response to HMG-CoA reductase inhibitors. Atherosclerosis 2002;163:213-22.
    • (2002) Atherosclerosis , vol.163 , pp. 213-222
    • Maitland-van der Zee, A.H.1    Klungel, O.H.2    Stricker, B.H.3
  • 148
    • 0036016315 scopus 로고    scopus 로고
    • Effect of apolipoprotein E, peroxisome proliferator-activated receptor alpha and lipoprotein lipase gene mutations on the ability of fenofibrate to improve lipid profiles and reach clinical guideline targets among hypertriglyceridemic patients
    • Brisson D, Ledoux K, Bossé Y, et al. Effect of apolipoprotein E, peroxisome proliferator-activated receptor alpha and lipoprotein lipase gene mutations on the ability of fenofibrate to improve lipid profiles and reach clinical guideline targets among hypertriglyceridemic patients. Pharmacogenetics 2002;12:313-20.
    • (2002) Pharmacogenetics , vol.12 , pp. 313-320
    • Brisson, D.1    Ledoux, K.2    Bossé, Y.3


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