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Volumn 68, Issue 3, 2005, Pages 99-105

The renoprotective potential of pentoxifylline in chronic kidney disease

Author keywords

Angiotensin II; Chronic kidney disease; Pentoxifylline

Indexed keywords

ANGIOTENSIN 2 RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITOR;

EID: 16844381073     PISSN: 17264901     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1726-4901(09)70228-X     Document Type: Review
Times cited : (19)

References (67)
  • 1
    • 0023189396 scopus 로고
    • Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy
    • Ward A, Clissold SP. Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy. Drugs 1987;34:50-97.
    • (1987) Drugs , vol.34 , pp. 50-97
    • Ward, A.1    Clissold, S.P.2
  • 2
    • 0032924098 scopus 로고    scopus 로고
    • Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney
    • Dousa TP. Cyclic-3′,5′-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney. Kidney Int 1999;55:29-62.
    • (1999) Kidney Int. , vol.55 , pp. 29-62
    • Dousa, T.P.1
  • 3
    • 0035188826 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases
    • Essayan DM. Cyclic nucleotide phosphodiesterases. J Allergy Clin Immunol 2001;108:671-80.
    • (2001) J. Allergy Clin. Immunol. , vol.108 , pp. 671-680
    • Essayan, D.M.1
  • 4
    • 0028348063 scopus 로고
    • Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation
    • Meskini N, Nemoz G, Okyayuz-Baklouti I, Lagarde M, Prigent AF. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem Pharmacol 1994;47:781-8.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 781-788
    • Meskini, N.1    Nemoz, G.2    Okyayuz-Baklouti, I.3    Lagarde, M.4    Prigent, A.F.5
  • 7
    • 0022443771 scopus 로고
    • Pentoxifylline, albumin excretion rate and proteinuria in type I and type II diabetic patients with microproteinuria. Results of a short-term randomized study
    • Solerte SB, Fioravanti M, Bozzetti A, Schifino N, Patti AL, Fedele P, Viola C, et al. Pentoxifylline, albumin excretion rate and proteinuria in type I and type II diabetic patients with microproteinuria. Results of a short-term randomized study. Acta Diabetol 1986;23:171-7.
    • (1986) Acta Diabetol. , vol.23 , pp. 171-177
    • Solerte, S.B.1    Fioravanti, M.2    Bozzetti, A.3    Schifino, N.4    Patti, A.L.5    Fedele, P.6    Viola, C.7
  • 9
    • 0028916941 scopus 로고
    • Vasodilator agents modulate rat glomerular mesangial cell growth and collagen synthesis
    • Tsai TJ, Lin RH, Chang CC, Chen YM, Chen CF, Ko FN, Teng CM. Vasodilator agents modulate rat glomerular mesangial cell growth and collagen synthesis. Nephron 1995; 70:91-100.
    • (1995) Nephron , vol.70 , pp. 91-100
    • Tsai, T.J.1    Lin, R.H.2    Chang, C.C.3    Chen, Y.M.4    Chen, C.F.5    Ko, F.N.6    Teng, C.M.7
  • 10
  • 11
    • 0032972830 scopus 로고    scopus 로고
    • Urinary protein excretion and serum tumor necrosis factor in diabetic patients with advanced renal failure: Effects of pentoxifylline administration
    • Navarro JF, Mora C, Rivero A, Gallego E, Chahin J, Macia M, Mendez ML, et al. Urinary protein excretion and serum tumor necrosis factor in diabetic patients with advanced renal failure: effects of pentoxifylline administration. Am J Kidney Dis 1999; 33:458-63.
    • (1999) Am. J. Kidney Dis. , vol.33 , pp. 458-463
    • Navarro, J.F.1    Mora, C.2    Rivero, A.3    Gallego, E.4    Chahin, J.5    Macia, M.6    Mendez, M.L.7
  • 13
    • 0035954017 scopus 로고    scopus 로고
    • Use of pentoxifylline in membranous nephropathy
    • Ducloux D, Bresson-Vautrin C, Chalopin JM. Use of pentoxifylline in membranous nephropathy. Lancet 2001;357: 1672-3.
    • (2001) Lancet , vol.357 , pp. 1672-1673
    • Ducloux, D.1    Bresson-Vautrin, C.2    Chalopin, J.M.3
  • 14
    • 0035002214 scopus 로고    scopus 로고
    • Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNF-α monoclonal antibody and by pentoxifylline
    • Segal R, Dayan M, Zinger H, Mozes E. Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNF-α monoclonal antibody and by pentoxifylline. Lupus 2001;10:23-31.
    • (2001) Lupus , vol.10 , pp. 23-31
    • Segal, R.1    Dayan, M.2    Zinger, H.3    Mozes, E.4
  • 16
    • 0141457722 scopus 로고    scopus 로고
    • Pentoxifylline inhibits platelet-derived growth factor-stimulated cyclin D1 expression in mesangial cells by blocking Akt membrane translocation
    • Lin SL, Chen RH, Chen YM, Chiang WC, Tsai TJ, Hsieh BS. Pentoxifylline inhibits platelet-derived growth factor-stimulated cyclin D1 expression in mesangial cells by blocking Akt membrane translocation. Mol Pharmacol 2003;64:811-22.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 811-822
    • Lin, S.L.1    Chen, R.H.2    Chen, Y.M.3    Chiang, W.C.4    Tsai, T.J.5    Hsieh, B.S.6
  • 17
    • 0043128884 scopus 로고    scopus 로고
    • Effects of pentoxifylline administration on urinary N-acetyl-β-glucosaminidase excretion in type 2 diabetic patients: A short-term, prospective randomized study
    • Navarro JF, Mora C, Muros M, Maca M, Garca J. Effects of pentoxifylline administration on urinary N-acetyl-β-glucosaminidase excretion in type 2 diabetic patients: a short-term, prospective randomized study. Am J Kidney Dis 2003; 42:264-70.
    • (2003) Am. J. Kidney Dis. , vol.42 , pp. 264-270
    • Navarro, J.F.1    Mora, C.2    Muros, M.3    Maca, M.4    Garca, J.5
  • 18
    • 2442462126 scopus 로고    scopus 로고
    • Pentoxifylline suppresses renal tumour necrosis factor-α and ameliorates experimental crescentic glomerulonephritis in rats
    • Chen YM, Ng YY, Lin SL, Chiang WC, Lan HY, Tsai TJ. Pentoxifylline suppresses renal tumour necrosis factor-α and ameliorates experimental crescentic glomerulonephritis in rats. Nephrol Dial Transplant 2004;19:1106-15.
    • (2004) Nephrol. Dial. Transplant. , vol.19 , pp. 1106-1115
    • Chen, Y.M.1    Ng, Y.Y.2    Lin, S.L.3    Chiang, W.C.4    Lan, H.Y.5    Tsai, T.J.6
  • 20
    • 0020324688 scopus 로고
    • Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease
    • Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 1982;307: 652-9.
    • (1982) N. Engl. J. Med. , vol.307 , pp. 652-659
    • Brenner, B.M.1    Meyer, T.W.2    Hostetter, T.H.3
  • 23
    • 0026541019 scopus 로고
    • Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model
    • Floege J, Burns MW, Alpers CE, Yoshimura A, Pritzl P, Gordon K, Seifert RA, et al. Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int 1992;41:297-309.
    • (1992) Kidney Int. , vol.41 , pp. 297-309
    • Floege, J.1    Burns, M.W.2    Alpers, C.E.3    Yoshimura, A.4    Pritzl, P.5    Gordon, K.6    Seifert, R.A.7
  • 24
    • 0028362076 scopus 로고
    • Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-β expression in rat glomerular mesangial cells
    • Kagami S, Border WA, Miller DE, Noble NA. Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-β expression in rat glomerular mesangial cells. J Clin Invest 1994;93:2431-7.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2431-2437
    • Kagami, S.1    Border, W.A.2    Miller, D.E.3    Noble, N.A.4
  • 25
    • 0033957976 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
    • Riser BL, Denichilo M, Cortes P, Baker C, Grondin JM, Yee J, Narins RG. Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J Am Soc Nephrol 2000;11:25-38.
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 25-38
    • Riser, B.L.1    Denichilo, M.2    Cortes, P.3    Baker, C.4    Grondin, J.M.5    Yee, J.6    Narins, R.G.7
  • 26
    • 0034112481 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (FGF-2) expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation
    • Strutz F, Zeisberg M, Hemmerlein B, Sattler B, Hummel K, Becker V, Muller GA. Basic fibroblast growth factor (FGF-2) expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation. Kidney Int 2000; 57:1521-38.
    • (2000) Kidney Int. , vol.57 , pp. 1521-1538
    • Strutz, F.1    Zeisberg, M.2    Hemmerlein, B.3    Sattler, B.4    Hummel, K.5    Becker, V.6    Muller, G.A.7
  • 27
    • 0037252248 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors are involved in the resolution or progression of renal disease
    • Anders HJ, Vielhauer V, Schlondorff D. Chemokines and chemokine receptors are involved in the resolution or progression of renal disease. Kidney Int 2003;63:401-15.
    • (2003) Kidney Int. , vol.63 , pp. 401-415
    • Anders, H.J.1    Vielhauer, V.2    Schlondorff, D.3
  • 28
    • 0141455352 scopus 로고    scopus 로고
    • Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor κB- and p38 mitogen-activated protein kinase-dependent pathways
    • Donadelli R, Zanchi C, Morigi M, Buelli S, Batani C, Tomasoni S, Corna D, et al. Protein overload induces fractalkine upregulation in proximal tubular cells through nuclear factor κB- and p38 mitogen-activated protein kinase-dependent pathways. J Am Soc Nephrol 2003;14:2436-46.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2436-2446
    • Donadelli, R.1    Zanchi, C.2    Morigi, M.3    Buelli, S.4    Batani, C.5    Tomasoni, S.6    Corna, D.7
  • 29
    • 0344465417 scopus 로고    scopus 로고
    • Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats
    • Chen YM, Hu-Tsai MI, Lin SL, Tsai TJ, Hsieh BS. Expression of CX3CL1/fractalkine by mesangial cells in vitro and in acute anti-Thy1 glomerulonephritis in rats. Nephrol Dial Transplant 2003;18:2505-14.
    • (2003) Nephrol. Dial. Transplant. , vol.18 , pp. 2505-2514
    • Chen, Y.M.1    Hu-Tsai, M.I.2    Lin, S.L.3    Tsai, T.J.4    Hsieh, B.S.5
  • 30
    • 0037351367 scopus 로고    scopus 로고
    • Inhibition by pentoxifylline of TNF-alpha-stimulated fractalkine production in vascular smooth muscle cells: Evidence for mediation by NF-κB down-regulation
    • Chen YM, Tu CJ, Hung KY, Wu KD, Tsai TJ, Hsieh BS. Inhibition by pentoxifylline of TNF-alpha-stimulated fractalkine production in vascular smooth muscle cells: evidence for mediation by NF-κB down-regulation. Br J Pharmacol 2003; 138:950-8.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 950-958
    • Chen, Y.M.1    Tu, C.J.2    Hung, K.Y.3    Wu, K.D.4    Tsai, T.J.5    Hsieh, B.S.6
  • 31
    • 0031626904 scopus 로고    scopus 로고
    • Signaling role of PDE isozymes in pathobiology of glomerular mesangial cells. Studies in vitro and in vivo
    • Dousa TP. Signaling role of PDE isozymes in pathobiology of glomerular mesangial cells. Studies in vitro and in vivo. Cell Biochem Biophys 1998;29:19-34.
    • (1998) Cell Biochem. Biophys. , vol.29 , pp. 19-34
    • Dousa, T.P.1
  • 32
    • 0041529686 scopus 로고    scopus 로고
    • Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras
    • Dumaz N, Marais R. Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. J Biol Chem 2003;278:29819-23.
    • (2003) J. Biol. Chem. , vol.278 , pp. 29819-29823
    • Dumaz, N.1    Marais, R.2
  • 33
    • 0028244071 scopus 로고
    • Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IV
    • Chini CS, Chini EN, Williams JM, Matousovic K, Dousa TP. Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IV. Kidney Int 1994;46:28-36.
    • (1994) Kidney Int. , vol.46 , pp. 28-36
    • Chini, C.S.1    Chini, E.N.2    Williams, J.M.3    Matousovic, K.4    Dousa, T.P.5
  • 34
    • 0030017253 scopus 로고    scopus 로고
    • Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV
    • Tsuboi Y, Shankland SJ, Grande JP, Walker HJ, Johnson RJ, Dousa TP. Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. J Clin Invest 1996;98: 262-70.
    • (1996) J. Clin. Invest. , vol.98 , pp. 262-270
    • Tsuboi, Y.1    Shankland, S.J.2    Grande, J.P.3    Walker, H.J.4    Johnson, R.J.5    Dousa, T.P.6
  • 36
    • 0037674864 scopus 로고    scopus 로고
    • Phosphodiesterase 4 inhibitors reduce human dendritic cell inflammatory cytokine production and Th1-polarizing capacity
    • Heystek HC, Thierry AC, Soulard P, Moulon C. Phosphodiesterase 4 inhibitors reduce human dendritic cell inflammatory cytokine production and Th1-polarizing capacity. Int Immunol 2003;15:827-35.
    • (2003) Int. Immunol. , vol.15 , pp. 827-835
    • Heystek, H.C.1    Thierry, A.C.2    Soulard, P.3    Moulon, C.4
  • 37
    • 0033617216 scopus 로고    scopus 로고
    • OPC-13013, a cyclic nucleotide phosphodiesterase type III inhibitor, inhibits cell proliferation and transdifferentiation of cultured rat hepatic stellate cells
    • Shimizu E, Kobayashi Y, Oki Y, Kawasaki T, Yoshimi T, Nakamura H. OPC-13013, a cyclic nucleotide phosphodiesterase type III inhibitor, inhibits cell proliferation and transdifferentiation of cultured rat hepatic stellate cells. Life Sci 1999;64: 2081-8.
    • (1999) Life Sci. , vol.64 , pp. 2081-2088
    • Shimizu, E.1    Kobayashi, Y.2    Oki, Y.3    Kawasaki, T.4    Yoshimi, T.5    Nakamura, H.6
  • 39
    • 0025806127 scopus 로고
    • Pentoxifylline and other methyl xanthines inhibit interleukin-2 receptor expression in human lymphocytes
    • Rao KM, Currie MS, McCachren SS, Cohen HJ. Pentoxifylline and other methyl xanthines inhibit interleukin-2 receptor expression in human lymphocytes. Cell Immunol 1991;135: 314-25.
    • (1991) Cell Immunol. , vol.135 , pp. 314-325
    • Rao, K.M.1    Currie, M.S.2    McCachren, S.S.3    Cohen, H.J.4
  • 40
    • 0029993357 scopus 로고    scopus 로고
    • Pentoxifylline, a phosphodiesterase inhibitor, induces immune deviation in patients with multiple sclerosis
    • Rieckmann P, Weber F, Gunther A, Martin S, Bitsch A, Broocks A, Kitze B, et al. Pentoxifylline, a phosphodiesterase inhibitor, induces immune deviation in patients with multiple sclerosis. J Neuroimmunol 1996;64:193-200.
    • (1996) J. Neuroimmunol. , vol.64 , pp. 193-200
    • Rieckmann, P.1    Weber, F.2    Gunther, A.3    Martin, S.4    Bitsch, A.5    Broocks, A.6    Kitze, B.7
  • 41
    • 0033810053 scopus 로고    scopus 로고
    • Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts
    • Strutz F, Heeg M, Kochsiek T, Siemers G, Zeisberg M, Muller GA. Effects of pentoxifylline, pentifylline and gamma-interferon on proliferation, differentiation, and matrix synthesis of human renal fibroblasts. Nephrol Dial Transplant 2000;15:1535-46.
    • (2000) Nephrol. Dial. Transplant. , vol.15 , pp. 1535-1546
    • Strutz, F.1    Heeg, M.2    Kochsiek, T.3    Siemers, G.4    Zeisberg, M.5    Muller, G.A.6
  • 42
    • 0030701875 scopus 로고    scopus 로고
    • Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity
    • Lee KS, Cottam HB, Houglum K, Wasson DB, Carson D, Chojkier M. Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity. Am J Physiol 1997;273:1094-100.
    • (1997) Am. J. Physiol. , vol.273 , pp. 1094-1100
    • Lee, K.S.1    Cottam, H.B.2    Houglum, K.3    Wasson, D.B.4    Carson, D.5    Chojkier, M.6
  • 43
    • 0033119248 scopus 로고    scopus 로고
    • Pentoxifylline inhibits PDGF-induced proliferation of and TGF-beta-stimulated collagen synthesis by vascular smooth muscle cells
    • Chen YM, Wu KD, Tsai TJ, Hsieh BS. Pentoxifylline inhibits PDGF-induced proliferation of and TGF-beta-stimulated collagen synthesis by vascular smooth muscle cells. J Mol Cell Cardiol 1999;3:773-83.
    • (1999) J. Mol. Cell Cardiol. , vol.3 , pp. 773-783
    • Chen, Y.M.1    Wu, K.D.2    Tsai, T.J.3    Hsieh, B.S.4
  • 44
    • 0028822281 scopus 로고
    • Suppression of lipopolysaccharide-induced tumour necrosis factor-α generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: Interaction with stimulants of adenylyl cyclase
    • Seldon PM, Barnes PJ, Meja K, Giembycz MA. Suppression of lipopolysaccharide-induced tumour necrosis factor-α generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Mol Pharmacol 1995;48:747-57.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 747-757
    • Seldon, P.M.1    Barnes, P.J.2    Meja, K.3    Giembycz, M.A.4
  • 45
    • 0028831965 scopus 로고
    • In vitro and in vivo effects of pentoxifylline on macrophages and lymphocytes derived from autoimmune MRL-lpr/lpr mice
    • Hecht M, Muller M, Lohmann-Matthes ML, Emmendorffer A. In vitro and in vivo effects of pentoxifylline on macrophages and lymphocytes derived from autoimmune MRL-lpr/lpr mice. J Leukoc Biol 1995;57:242-9.
    • (1995) J. Leukoc. Biol. , vol.57 , pp. 242-249
    • Hecht, M.1    Muller, M.2    Lohmann-Matthes, M.L.3    Emmendorffer, A.4
  • 46
    • 0033057224 scopus 로고    scopus 로고
    • Induction of CC chemokines in human peripheral blood mononuclear cells by staphylococcal exotoxins and its prevention by pentoxifylline
    • Krakauer T. Induction of CC chemokines in human peripheral blood mononuclear cells by staphylococcal exotoxins and its prevention by pentoxifylline. J Leukoc Biol 1999;66:158-64.
    • (1999) J. Leukoc. Biol. , vol.66 , pp. 158-164
    • Krakauer, T.1
  • 47
    • 0031749820 scopus 로고    scopus 로고
    • Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation
    • Zoja C, Donadelli R, Colleoni S, Figliuzzi M, Bonazzola S, Morigi M, Remuzzi G. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-κB activation. Kidney Int 1998;53:1608-15.
    • (1998) Kidney Int. , vol.53 , pp. 1608-1615
    • Zoja, C.1    Donadelli, R.2    Colleoni, S.3    Figliuzzi, M.4    Bonazzola, S.5    Morigi, M.6    Remuzzi, G.7
  • 48
    • 0032991086 scopus 로고    scopus 로고
    • Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor-κB in proximal tubule cells
    • Wang Y, Rangan GK, Tay YC, Wang Y, Harris DCH. Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor-κB in proximal tubule cells. J Am Soc Nephrol 1999;10:1204-13.
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 1204-1213
    • Wang, Y.1    Rangan, G.K.2    Tay, Y.C.3    Wang, Y.4    Harris, D.C.H.5
  • 49
    • 0030046730 scopus 로고    scopus 로고
    • Substituted xanthines, pteridinediones, and related compounds as potential anti-inflammatory agents. Synthesis and biological evaluation of inhibitors of tumour necrosis factor alpha
    • Cottam HB, Shih H, Tehrani LR, Wasson DB, Carson DA. Substituted xanthines, pteridinediones, and related compounds as potential anti-inflammatory agents. Synthesis and biological evaluation of inhibitors of tumour necrosis factor alpha. J Med Chem 1996;39:2-9.
    • (1996) J. Med. Chem. , vol.39 , pp. 2-9
    • Cottam, H.B.1    Shih, H.2    Tehrani, L.R.3    Wasson, D.B.4    Carson, D.A.5
  • 50
    • 2442680279 scopus 로고    scopus 로고
    • Dual regulation of TNF-α-induced CCL2/monocyte chemoattractant protein-1 expression in vascular smooth muscle sells by NF-κB and AP-1: Modulation by type III phosphodiesterase inhibition
    • Chen YM, Chiang WC, Lin SL, Wu KD, Tsai TJ, Hsieh BS. Dual regulation of TNF-α-induced CCL2/monocyte chemoattractant protein-1 expression in vascular smooth muscle sells by NF-κB and AP-1: modulation by type III phosphodiesterase inhibition. J Pharmacol Exp Ther 2004;309:978-86.
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 978-986
    • Chen, Y.M.1    Chiang, W.C.2    Lin, S.L.3    Wu, K.D.4    Tsai, T.J.5    Hsieh, B.S.6
  • 52
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes. N Engl J Med 1993;329:977-86.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
  • 53
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS33). Lancet 1998;352: 837-53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 54
    • 0028215329 scopus 로고
    • The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease
    • Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, Striker G. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. N Engl J Med 1994;330:877-84.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 877-884
    • Klahr, S.1    Levey, A.S.2    Beck, G.J.3    Caggiula, A.W.4    Hunsicker, L.5    Kusek, J.W.6    Striker, G.7
  • 55
    • 0031779392 scopus 로고    scopus 로고
    • A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function
    • Kasiske BL, Lakatua JD, Ma JZ, Louis TA. A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function. Am J Kidney Dis 1998;31:954-61.
    • (1998) Am. J. Kidney Dis. , vol.31 , pp. 954-961
    • Kasiske, B.L.1    Lakatua, J.D.2    Ma, J.Z.3    Louis, T.A.4
  • 56
    • 0027517659 scopus 로고
    • The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy
    • Lewis EJ, Hunsicker LG, Bain RP, Rohde RD. The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. N Engl J Med 1993;329:1456-62.
    • (1993) N. Engl. J. Med. , vol.329 , pp. 1456-1462
    • Lewis, E.J.1    Hunsicker, L.G.2    Bain, R.P.3    Rohde, R.D.4
  • 57
    • 0035902622 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data
    • Jafar TH, Schmid CH, Landa M, Giatras I, Toto R, Remuzzi G, Maschio G, et al. Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data. Ann Intern Med 2001;135:73-87.
    • (2001) Ann. Intern. Med. , vol.135 , pp. 73-87
    • Jafar, T.H.1    Schmid, C.H.2    Landa, M.3    Giatras, I.4    Toto, R.5    Remuzzi, G.6    Maschio, G.7
  • 58
    • 0035922444 scopus 로고    scopus 로고
    • Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Brochner-Mortensen I, Gomis R, Andersen S, Arner P. Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria Study Group. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001;345:870-8.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Brochner-Mortensen, I.3    Gomis, R.4    Andersen, S.5    Arner, P.6
  • 59
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, Ritz E, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-60.
    • (2001) N. Engl. J. Med. , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3    Berl, T.4    Pohl, M.A.5    Lewis, J.B.6    Ritz, E.7
  • 61
    • 0033060074 scopus 로고    scopus 로고
    • Combining an anti-proteinuric approach with mycophenolate mofetil fully suppresses progressive nephropathy of experimental animals
    • Remuzzi G, Zoja C, Gagliardini E, Corna D, Abbate M, Benigni A. Combining an anti-proteinuric approach with mycophenolate mofetil fully suppresses progressive nephropathy of experimental animals. J Am Soc Nephrol 1999;10: 1542-9.
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 1542-1549
    • Remuzzi, G.1    Zoja, C.2    Gagliardini, E.3    Corna, D.4    Abbate, M.5    Benigni, A.6
  • 63
    • 0034627208 scopus 로고    scopus 로고
    • Randomized controlled trial of dual blockage of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microabluminuria (CALM) study
    • Mogensen CE, Neldam S, Tikkanen I, Oren S, Viskoper R, Watts RW, Cooper ME. Randomized controlled trial of dual blockage of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the candesartan and lisinopril microabluminuria (CALM) study. BMJ 2000;321:1440-4.
    • (2000) BMJ , vol.321 , pp. 1440-1444
    • Mogensen, C.E.1    Neldam, S.2    Tikkanen, I.3    Oren, S.4    Viskoper, R.5    Watts, R.W.6    Cooper, M.E.7
  • 64
  • 66
    • 0037431774 scopus 로고    scopus 로고
    • Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal discase (COOPERATE): A randomized controlled trial
    • Nakao N, Yoshimura A, Morita H, Takada M, Kayano T, Ideura T. Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal discase (COOPERATE): a randomized controlled trial. Lancet 2003; 361:117-24.
    • (2003) Lancet , vol.361 , pp. 117-124
    • Nakao, N.1    Yoshimura, A.2    Morita, H.3    Takada, M.4    Kayano, T.5    Ideura, T.6
  • 67
    • 0037222490 scopus 로고    scopus 로고
    • Effectiveness of aldosterone blockade in patients with diabetic nephropathy
    • Sato A, Hayashi K, Naruse M, Saruta T. Effectiveness of aldosterone blockade in patients with diabetic nephropathy. Hypertension 2003;41:64-8.
    • (2003) Hypertension , vol.41 , pp. 64-68
    • Sato, A.1    Hayashi, K.2    Naruse, M.3    Saruta, T.4


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