Pentoxifylline blocks hepatic stellate cell activation independently of phosphodiesterase inhibitory activity

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 273, Issue 5 36-5, 1997, Pages

  Lee, Kwan S ^a,b   Cottam, Howard B ^c   Houglum, Karl ^a   Bruce Wasson, D ^c   Carson, Dennis ^c   Chojkier, Mario ^a  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c University of California San Diego   (United States)

Author keywords

C myb expression; CREB phosphorylation; Liver fibrogenesis

Indexed keywords

ALPHA ACTIN; CARBON TETRACHLORIDE; COLLAGEN TYPE 1; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; DRUG METABOLITE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PENTOXIFYLLINE; PHOSPHODIESTERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL CYCLE S PHASE; CONTROLLED STUDY; ENZYME INHIBITION; LIVER CELL; LIVER FIBROSIS; MALE; MOUSE; NONHUMAN; ONCOGENE C MYB; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RAT; STELLATE CELL;

EID: 0030701875     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.273.5.g1094     Document Type: Article

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