메뉴 건너뛰기




Volumn 27, Issue 4, 2004, Pages 407-414

Histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in HepG2 cells

Author keywords

CYP3A4; HDAC; HepG2; IN2001; PCN; Rifampicin; RU486; SXR

Indexed keywords

CYP3A PROTEIN, HUMAN; CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450; ENZYME INHIBITOR; HISTONE DEACETYLASE;

EID: 16544376032     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/bf02980082     Document Type: Article
Times cited : (12)

References (26)
  • 1
    • 0029992789 scopus 로고    scopus 로고
    • Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit Hepa-Itocytes
    • Barwick, J. L., Quattrochi, L. C., Mills, A. S., Potenza, C., Tukey, R. H., and Guzelian, P. S., Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit Hepa-Itocytes. Mol. Pharmacol., 50, 10-16 (1996).
    • (1996) Mol. Pharmacol. , vol.50 , pp. 10-16
    • Barwick, J.L.1    Quattrochi, L.C.2    Mills, A.S.3    Potenza, C.4    Tukey, R.H.5    Guzelian, P.S.6
  • 2
    • 0037067665 scopus 로고    scopus 로고
    • Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human Hepa-Itocytes
    • Drocourt, L., Ourlin, J. C., Pascussi, J. M., Maurel, P., and Vilarem, M. J., Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human Hepa-Itocytes. J. Biol. Chem., 277, 25125-25132 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 25125-25132
    • Drocourt, L.1    Ourlin, J.C.2    Pascussi, J.M.3    Maurel, P.4    Vilarem, M.J.5
  • 3
    • 0010258751 scopus 로고    scopus 로고
    • Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: Role of the glucocorticoid and pregnane X receptors
    • Gibson, G. G., Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: Role of the glucocorticoid and pregnane X receptors. Drug Metab. Dispos., 28, 493-496 (2000).
    • (2000) Drug Metab. Dispos. , vol.28 , pp. 493-496
    • Gibson, G.G.1
  • 4
    • 0032702726 scopus 로고    scopus 로고
    • The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
    • Goodwin, B., Hodgson, E., and Liddle, C., The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol. Pharmacol., 56, 1329-1339 (1999).
    • (1999) Mol. Pharmacol. , vol.56 , pp. 1329-1339
    • Goodwin, B.1    Hodgson, E.2    Liddle, C.3
  • 5
    • 0032924934 scopus 로고    scopus 로고
    • Cytochrome p-450 3A4: Regulation and role in drug metabolism
    • Guengerich, F. P., Cytochrome p-450 3A4: Regulation and role in drug metabolism, Annu. Rev. Pharmacol. Toxicol., 39, 1-17 (1999).
    • (1999) Annu. Rev. Pharmacol. Toxicol. , vol.39 , pp. 1-17
    • Guengerich, F.P.1
  • 6
    • 0027137429 scopus 로고
    • Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control
    • Hashimoto, H., Toide, K., Kitamura, R., Fujita, M., Tagawa, S., Itoh, S., and Kamataki, T., Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control. Eur. J. Biochem., 218, 585-595 (1993).
    • (1993) Eur. J. Biochem. , vol.218 , pp. 585-595
    • Hashimoto, H.1    Toide, K.2    Kitamura, R.3    Fujita, M.4    Tagawa, S.5    Itoh, S.6    Kamataki, T.7
  • 7
    • 0026538997 scopus 로고
    • Genomic organization of human fetal specific P-450IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5′ flanking region
    • Itoh, S., Yanagimoto, T., Tagawa, S., Hashimoto, H., Kitamura, R., Nakajima, Y., Okochi, T., Fujimoto, S., Uchino, J., and Kamataki, T., Genomic organization of human fetal specific P-450IIIA7 (cytochrome P-450HFLa)-related gene(s) and interaction of transcriptional regulatory factor with its DNA element in the 5′ flanking region. Biochim. Biophys. Acta, 1130, 133-138 (1992).
    • (1992) Biochim. Biophys. Acta , vol.1130 , pp. 133-138
    • Itoh, S.1    Yanagimoto, T.2    Tagawa, S.3    Hashimoto, H.4    Kitamura, R.5    Nakajima, Y.6    Okochi, T.7    Fujimoto, S.8    Uchino, J.9    Kamataki, T.10
  • 9
    • 0028918996 scopus 로고
    • Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human Hepa-Itocytes
    • Kocarek, T. A., Schuetz, E. G., Strom, S. C., Fisher, R. A., and Guzelian, P. S., Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human Hepa-Itocytes. Drug Metab. Dispos., 23, 415-421 (1995).
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 415-421
    • Kocarek, T.A.1    Schuetz, E.G.2    Strom, S.C.3    Fisher, R.A.4    Guzelian, P.S.5
  • 10
    • 0029584276 scopus 로고
    • Substrates of human Hepa-Itic cytochrome P450 3A4
    • Li, A. P., Kaminski, D. L., and Rasmussen, A., Substrates of human Hepa-Itic cytochrome P450 3A4. Toxicology, 104, 1-8 (1995).
    • (1995) Toxicology , vol.104 , pp. 1-8
    • Li, A.P.1    Kaminski, D.L.2    Rasmussen, A.3
  • 11
    • 0031785886 scopus 로고    scopus 로고
    • Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone, and growth hormone in cultured Hepa-Itocytes
    • Liddle, C., Goodwin, B. J., George, J., Tapner, M., and Farrell, G. C., Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone, and growth hormone in cultured Hepa-Itocytes. J. Clin. Endocrinol. Metab., 83, 2411-2416 (1998).
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 2411-2416
    • Liddle, C.1    Goodwin, B.J.2    George, J.3    Tapner, M.4    Farrell, G.C.5
  • 13
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf, D. J., and Evans, R. M., The RXR heterodimers and orphan receptors. Cell, 83, 841-850 (1995).
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 15
    • 0035106562 scopus 로고    scopus 로고
    • PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors
    • Mathur, M., Tucker P. W., and Samuels, H. H., PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors. Mol. Cell Biol., 21, 2298-2311 (2001).
    • (2001) Mol. Cell Biol. , vol.21 , pp. 2298-2311
    • Mathur, M.1    Tucker, P.W.2    Samuels, H.H.3
  • 16
    • 0031975185 scopus 로고    scopus 로고
    • Update: Clinically significant cytochrome P-450 drug interactions
    • Michalets, E. L., Update: clinically significant cytochrome P-450 drug interactions. Pharmacotherapy, 18, 84-112 (1998).
    • (1998) Pharmacotherapy , vol.18 , pp. 84-112
    • Michalets, E.L.1
  • 17
    • 0041631065 scopus 로고    scopus 로고
    • Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells
    • Nakajima, A., Iwanari, M., and Yokoi, T., Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells. Toxicol. Lett., 144, 247-256 (2003).
    • (2003) Toxicol. Lett. , vol.144 , pp. 247-256
    • Nakajima, A.1    Iwanari, M.2    Yokoi, T.3
  • 18
    • 0033000991 scopus 로고    scopus 로고
    • A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro
    • Ogg, M. S., Williams, J. M., Tarbit, M., Goldfarb, P. S., Grays, T. J. B., and Gibson, G. G., A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica, 29, 269-279 (1999).
    • (1999) Xenobiotica , vol.29 , pp. 269-279
    • Ogg, M.S.1    Williams, J.M.2    Tarbit, M.3    Goldfarb, P.S.4    Grays, T.J.B.5    Gibson, G.G.6
  • 19
    • 0037450436 scopus 로고    scopus 로고
    • The expression of CYP2B6, CYP2C9 and CYP3A4 genes, a tangle of networks of nuclear and steroid receptors
    • Pascussi, J. M., Gerbal-Chaloin, S., Drocourt, L., Maurel, P., and Vilarem, M. J., The expression of CYP2B6, CYP2C9 and CYP3A4 genes, a tangle of networks of nuclear and steroid receptors. Biochim. Biophysic. Act., 1619, 243-253 (2003).
    • (2003) Biochim. Biophysic. Act. , vol.1619 , pp. 243-253
    • Pascussi, J.M.1    Gerbal-Chaloin, S.2    Drocourt, L.3    Maurel, P.4    Vilarem, M.J.5
  • 20
    • 0030916336 scopus 로고    scopus 로고
    • Whats up and down with histone deacetylation and transcription?
    • Pazin, M. J., and Kadonaga, J. T., Whats up and down with histone deacetylation and transcription? Cell, 89, 325-328 (1997).
    • (1997) Cell , vol.89 , pp. 325-328
    • Pazin, M.J.1    Kadonaga, J.T.2
  • 21
    • 0027427551 scopus 로고
    • Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human Hepatocytes
    • Schuetz, E. G., Schuetz, J. D., Strom, S. C., Thompson, M. T., Fisher, R. A., Molowa, D. T., Li, D., and Guzelian, P. S., Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human Hepatocytes. Hepatology, 18, 1254-1262 (1993).
    • (1993) Hepatology , vol.18 , pp. 1254-1262
    • Schuetz, E.G.1    Schuetz, J.D.2    Strom, S.C.3    Thompson, M.T.4    Fisher, R.A.5    Molowa, D.T.6    Li, D.7    Guzelian, P.S.8
  • 22
    • 0033525886 scopus 로고    scopus 로고
    • The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
    • Sueyoshi, T., Kawamoto, T., Zelko, I., Honkakoski, P., and Negishi, M., The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J. Biol. Chem., 274, 6043-6046 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 6043-6046
    • Sueyoshi, T.1    Kawamoto, T.2    Zelko, I.3    Honkakoski, P.4    Negishi, M.5
  • 23
    • 0035038919 scopus 로고    scopus 로고
    • The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux
    • Synold, T. W., Dussault, I., and Forman, B. M., The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat. Med., 7, 584-590 (2001).
    • (2001) Nat. Med. , vol.7 , pp. 584-590
    • Synold, T.W.1    Dussault, I.2    Forman, B.M.3
  • 24
    • 0037031809 scopus 로고    scopus 로고
    • Putative role of the orphan nuclear receptor SXR in the mechanism of CYP3A4 inhibition by Xenobiotics
    • Takeshita, A., Taguchi, M., Koibuchi, N., and Ozawa, Y., Putative role of the orphan nuclear receptor SXR in the mechanism of CYP3A4 inhibition by Xenobiotics. J. Biol. Chem., 277, 32453-32458 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 32453-32458
    • Takeshita, A.1    Taguchi, M.2    Koibuchi, N.3    Ozawa, Y.4
  • 26
    • 0030695332 scopus 로고    scopus 로고
    • Chromatin remodeling and the control of gene expression
    • Wu, C., Chromatin remodeling and the control of gene expression. J. Biol. Chem., 272, 28171-28174 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 28171-28174
    • Wu, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.