-
1
-
-
0025731583
-
Structure and function of telomeres
-
Blackbum, E. H. Structure and function of telomeres. Nature (Lond.), 350: 569-573, 1991.
-
(1991)
Nature (Lond.)
, vol.350
, pp. 569-573
-
-
Blackbum, E.H.1
-
2
-
-
0032522443
-
The telomerase reverse transcriptase: Components and regulation
-
Nugent, C. I., and Lundblad, V. The telomerase reverse transcriptase: components and regulation. Genes Dev., 12: 1073-1085, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 1073-1085
-
-
Nugent, C.I.1
Lundblad, V.2
-
3
-
-
0037148330
-
Many ways to telomere dysfunction: In vivo studies using mouse models
-
Goytisolo, F. A., and Blasco, M. A. Many ways to telomere dysfunction: in vivo studies using mouse models. Oncogene, 21: 584-591, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 584-591
-
-
Goytisolo, F.A.1
Blasco, M.A.2
-
4
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco, M. A., Lee, H. W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., and Greider, C. W. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell, 91: 25-34, 1997.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
5
-
-
0033822365
-
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
-
Wong, K. K., Chang, S., Weiler, S. R., Ganesan, S., Chaudhuri, J., Zhu, C., Artandi, S. E., Rudolph, K. L., Gottlieb, G. J., Chin, L., Alt, F. W., and DePinho, R. A. Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation. Nat. Genet., 26: 85-88, 2000.
-
(2000)
Nat. Genet.
, vol.26
, pp. 85-88
-
-
Wong, K.K.1
Chang, S.2
Weiler, S.R.3
Ganesan, S.4
Chaudhuri, J.5
Zhu, C.6
Artandi, S.E.7
Rudolph, K.L.8
Gottlieb, G.J.9
Chin, L.10
Alt, F.W.11
DePinho, R.A.12
-
6
-
-
0034606226
-
Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals
-
Goytisolo, F. A., Samper, E., Martin-Caballero, J., Finnon, P., Herrera, E., Flores, J. M., Bouffler, S. D., and Blasco, M. A. Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals. J. Exp. Med., 192: 1625-1636, 2000.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1625-1636
-
-
Goytisolo, F.A.1
Samper, E.2
Martin-Caballero, J.3
Finnon, P.4
Herrera, E.5
Flores, J.M.6
Bouffler, S.D.7
Blasco, M.A.8
-
7
-
-
0035853058
-
Telomere dysfunction alters the chemotherapeutic profile of transformed cells
-
Lee, K. H., Rudolph, K. L., Ju, Y. J., Greenberg, R. A., Cannizzaro, L., Chin, L., Weiler, S. R., and DePinho, R. A. Telomere dysfunction alters the chemotherapeutic profile of transformed cells. Proc Natl. Acad. Sci. USA, 98: 3381-3386, 2001.
-
(2001)
Proc Natl. Acad. Sci. USA
, vol.98
, pp. 3381-3386
-
-
Lee, K.H.1
Rudolph, K.L.2
Ju, Y.J.3
Greenberg, R.A.4
Cannizzaro, L.5
Chin, L.6
Weiler, S.R.7
DePinho, R.A.8
-
8
-
-
0343228751
-
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
-
González-Suárez, E., Samper, E., Flores, J. M., and Blasco, M. A. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat. Genet., 26: 114-117, 2000.
-
(2000)
Nat. Genet.
, vol.26
, pp. 114-117
-
-
González-Suárez, E.1
Samper, E.2
Flores, J.M.3
Blasco, M.A.4
-
9
-
-
0034667383
-
6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent
-
6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent. Cancer Res., 60: 5815-5824, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 5815-5824
-
-
Ochs, K.1
Kaina, B.2
-
10
-
-
0036270993
-
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis
-
Bernstein, C., Bernstein, H., Payne, C. M., and Garewal, H. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat. Res., 511: 145-178, 2002.
-
(2002)
Mutat. Res.
, vol.511
, pp. 145-178
-
-
Bernstein, C.1
Bernstein, H.2
Payne, C.M.3
Garewal, H.4
-
11
-
-
0035754825
-
Nitrosomethylurea: 30 Years of study and use in the treatment of cancer patients
-
Dement'eva, N. P., and Korman, D. B. Nitrosomethylurea: 30 years of study and use in the treatment of cancer patients (in Russian). Vopr. Onkol., 47: 655-661, 2001.
-
(2001)
Vopr. Onkol.
, vol.47
, pp. 655-661
-
-
Dement'eva, N.P.1
Korman, D.B.2
-
12
-
-
0033153424
-
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres
-
Herrera, E., Samper, E., Martin-Caballero, J., Flores, J. M., Lee, H. W., and Blasco, M. A. Disease states associated with telomerase deficiency appear earlier in mice with short telomeres. EMBO J., 18: 2950-2960, 1999.
-
(1999)
EMBO J.
, vol.18
, pp. 2950-2960
-
-
Herrera, E.1
Samper, E.2
Martin-Caballero, J.3
Flores, J.M.4
Lee, H.W.5
Blasco, M.A.6
-
13
-
-
0028046180
-
Comparative mutagenicity of chemicals selected for test in the International Program on Chemical Safety's collaborative study on plant systems for the detection of environmental mutagens
-
Grant, W. F., and Salamone, M. F. Comparative mutagenicity of chemicals selected for test in the International Program on Chemical Safety's collaborative study on plant systems for the detection of environmental mutagens. Mutat. Res., 310: 187-209, 1994.
-
(1994)
Mutat. Res.
, vol.310
, pp. 187-209
-
-
Grant, W.F.1
Salamone, M.F.2
-
14
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn, W. C., Stewart, S. A., Brooks, M. W., York, S. G., Eaton, E., Kurachi, A., Beijersbergen, R. L., Knoll, J. H., Meyerson, M., and Weinberg, R. A. Inhibition of telomerase limits the growth of human cancer cells. Nat. Med., 5: 1164-1170, 1999.
-
(1999)
Nat. Med.
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Kurachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.8
Meyerson, M.9
Weinberg, R.A.10
-
15
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee, H. W., Blasco, M. A., Gottlieb, G. J., Homer, J. W., II, Greider, C. W., and DePinho, R. A. Essential role of mouse telomerase in highly proliferative organs. Nature (Lond.), 392: 569-574, 1998.
-
(1998)
Nature (Lond.)
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
Homer II, J.W.4
Greider, C.W.5
DePinho, R.A.6
-
16
-
-
0037987939
-
Telomerase and tumorigenesis
-
Masutomi, K., and Hahn, W. C. Telomerase and tumorigenesis. Cancer Lett., 194: 163-172, 2003.
-
(2003)
Cancer Lett.
, vol.194
, pp. 163-172
-
-
Masutomi, K.1
Hahn, W.C.2
-
17
-
-
0036674425
-
Telomerase beyond telomeres
-
Blasco, M. A. Telomerase beyond telomeres. Nat. Rev. Cancer, 2: 627-633, 2002.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 627-633
-
-
Blasco, M.A.1
-
18
-
-
0035149823
-
Emerging roles for telomerase in neuronal development and apoptosis
-
Mattson, M. P., and Klapper, W. Emerging roles for telomerase in neuronal development and apoptosis. J. Neurosci. Res., 63: 1-9, 2001.
-
(2001)
J. Neurosci. Res.
, vol.63
, pp. 1-9
-
-
Mattson, M.P.1
Klapper, W.2
-
19
-
-
0035355340
-
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes
-
Gonzalez-Suarez, E., Samper, E., Ramirez, A., Flores, J. M., Martin-Caballero, J., Jorcano, J. L., and Blasco, M. A. Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. EMBO J., 20, 2619-2630, 2001.
-
(2001)
EMBO J.
, vol.20
, pp. 2619-2630
-
-
Gonzalez-Suarez, E.1
Samper, E.2
Ramirez, A.3
Flores, J.M.4
Martin-Caballero, J.5
Jorcano, J.L.6
Blasco, M.A.7
-
20
-
-
0037062454
-
Constitutive telomerase expression promotes mammary carcinomas in aging mice
-
Artandi, S. E., Alson, S., Tietze, M. K., Sharpless, N. E., Ye, S., Greenberg, R. A., Castrillon, D. H., Homer, J. W., Weiler, S. R., Carrasco, R. D., and DePinho, R. A. Constitutive telomerase expression promotes mammary carcinomas in aging mice. Proc. Natl. Acad. Sci. USA, 99: 8191-8196, 2002.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8191-8196
-
-
Artandi, S.E.1
Alson, S.2
Tietze, M.K.3
Sharpless, N.E.4
Ye, S.5
Greenberg, R.A.6
Castrillon, D.H.7
Homer, J.W.8
Weiler, S.R.9
Carrasco, R.D.10
DePinho, R.A.11
-
21
-
-
0042203612
-
Shortened telomeres join DNA breaks interfering with their correct repair
-
Latre, L., Tussell, L., Martin, M., Miro, R., Egozcue, J., Blasco, M. A., and Genesca, A. Shortened telomeres join DNA breaks interfering with their correct repair. Exp. Cell Res., 287: 282-288, 2003.
-
(2003)
Exp. Cell Res.
, vol.287
, pp. 282-288
-
-
Latre, L.1
Tussell, L.2
Martin, M.3
Miro, R.4
Egozcue, J.5
Blasco, M.A.6
Genesca, A.7
-
22
-
-
0037335614
-
Aging and telomeres: A study into organ- and gender-specific telomere shortening
-
Cherif, H., Tarry, J. L., Ozanne, S. E., and Hales, C. N. Aging and telomeres: a study into organ- and gender-specific telomere shortening. Nucleic Acids Res., 31: 1576-1583, 2003.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 1576-1583
-
-
Cherif, H.1
Tarry, J.L.2
Ozanne, S.E.3
Hales, C.N.4
-
23
-
-
0023091969
-
Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate
-
Li, J. L., Okada, S., Hamazaki, S., Ebina, Y., and Midorikawa, O. Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate. Cancer Res., 47: 1867-1869, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 1867-1869
-
-
Li, J.L.1
Okada, S.2
Hamazaki, S.3
Ebina, Y.4
Midorikawa, O.5
|