Potential role of major histocompatibility complex class II peptides in regulatory tolerance to vascularized grafts

Transplantation

Volumn 77, Issue 1 SUPPL., 2004, Pages

  Leguern, Christian ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLOGRAFT; CONFERENCE PAPER; GENE THERAPY; HUMAN; IMMUNOLOGICAL TOLERANCE; KIDNEY GRAFT; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 1642535327     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000106472.91343.8d     Document Type: Conference Paper

References (31)

1. van Meerwijk JP, Marguerat S, Lees RK, et al. Quantitative impact of thymic clonal deletion on the T cell repertoire. J Exp Med 1997; 185: 377.
2. Boussiotis VA, Freeman GJ, Taylor PA, et al. p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes. Nat Med 2000; 6: 290.
3. Groux H, O'Garra A, Bigler M, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737.
4. Chen Y, Kuchroo VK, Inobe J, et al. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis. Science 1994; 265: 1237.
5. Sakaguchi S. Regulatory T cells: Key controllers of immunologic self-tolerance. Cell 2000; 101: 455.
6. Sprent J, Kishimoto H. The thymus and negative selection. Immunol Rev 2002; 185: 126.
7. Sykes M. Chimerism and central tolerance. Curr Opin Immunol 1996; 8: 694.
8. Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3: 199.
9. Davies JD, Leong LY, Mellor A, et al. T cell suppression in transplantation tolerance through linked recognition. J Immunol 1996; 156: 3602.
10. Marelli-Berg FM, Weetman A, Frasca L, et al. Antigen presentation by epithelial cells induces anergic immunoregulatory CD45RO+ T cells and deletion of CD45RA+ T cells. J Immunol 1997; 159: 5853.
11. Hall BM, Jelbart ME, Gurley KE, et al. Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine: Mediation of specific suppression by T helper/inducer cells. J Exp Med 1985; 162: 1683.
12. Waldmann H, Cobbold S. Regulating the immune response to transplants: A role for CD4+ regulatory cells? Immunity 2001; 14: 399.
13. Kingsley CI, Karim M, Bushell AR, et al. CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J Immunol 2002; 168: 1080.
14. Levings MK, Sangregorio R, Roncarolo MG. Human cd25(+)cd4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J Exp Med 2001; 193: 1295.
15. Jonuleit H, Schmitt E, Stassen M, et al. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001; 193: 1285.
16. Dieckmann D, Plottner H, Berchtold S, et al. Ex vivo isolation and characterization of (CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001; 193: 1303.
17. Rosengard BR, Ojikutu CA, Guzzetta PC, et al. Induction of specific tolerance to class I-disparate renal allografts in miniature swine with cyclosporine. Transplantation 1992; 54: 490.
18. Opelz G, Wujciak T, Dohler B, et al. HLA compatibility and organ transplant survival: Collaborative Transplant Study. Rev Immunogenet 1999; 1: 334.
19. LeGuern C, Shimada H, Emery DW, et al. Retrovirus-mediated transfer of MHC class II cDNA into swine bone marrow cells. J Mol Med 1995; 73: 269.
20. Emery DW, Sablinski T, Shimada H, et al. Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity. Transplantation 1997; 64: 1414.
21. Sonntag KC, Emery DW, Yasumoto A, et al. Tolerance to solid organ transplants through transfer of MHC class II genes. J Clin Invest 2001; 107: 65.
22. Fraser CC, Sykes M, Stanton-Lee R, et al. Specific unresponsiveness to retrovirally-transferred class I antigen is controlled through the helper pathway. J Immunol 1995; 154: 1587.
23. Denaro M, Kolber-Simonds D, Schad V, et al. Expression of xenogeneic MHC class II molecules in HLA-DR+ and negative cells: Influence of retrovirus vector design and cellular context. Xenotransplantation 2002; 2: 115.
24. Brocker T, Riedinger M, Karjalainen K. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo. J Exp Med 1997; 185: 541.
25. Rosengard BR, Kortz EO, Ojikutu CA, et al. The failure of skin grafting to break tolerance to class I-disparate renal allografts in miniature swine despite inducing marked antidonor cellular immunity. Transplantation 1991; 52: 1044.
26. Ierino FL, Yamada K, Hatch T, et al. Peripheral tolerance to class I mismatched renal allografts in miniature swine: Donor antigen-activated peripheral blood lymphocytes from tolerant swine inhibit antidonor CTL reactivity. J Immunol 1999; 162: 550.
27. Olivares-Villagomez D, Wand Y, Lafaille JJ. Regulatory CD4+ T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J Exp Med 1998; 188: 1883.
28. Sprent J, Kishimoto H. The thymus and central tolerance. Philos Trans R Soc Lond B Biol Sci 2001; 356: 609.
29. Chicz RM, Urban RG, Gorga JC, et al. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med 1993; 178: 27.
30. Chicz RM, Lane WS, Robinson RA, et al. Self-peptides bound to the type I diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8. Int Immunol 1994; 6: 1639.
31. Rudensky AY, Rath S, Preston-Hurlburt P, et al. On the complexity of self. Nature 1991; 353: 660.