Animal model: Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis during allergic airway disease induced by Aspergillus fumigatus

American Journal of Pathology

Volumn 156, Issue 2, 2000, Pages 723-732

  Hogaboam, Cory M ^a   Blease, Kate ^a   Mehrad, Borna ^a   Steinhauser, Matthew L ^a   Standiford, Theodore J ^a   Kunkel, Steven L ^a   Lukacs, Nicholas W ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN E; GAMMA INTERFERON; HYDROXYPROLINE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; ASPERGILLUS FUMIGATUS; BLOOD; BRONCHUS; BRONCHUS HYPERREACTIVITY; CBA MOUSE; CHRONIC DISEASE; CYTOLOGY; EOSINOPHIL; FEMALE; FIBROSIS; GOBLET CELL; HYPERPLASIA; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOLOGY; LUNG; LUNG LAVAGE; LYMPHOCYTE; METABOLISM; MOUSE; PATHOLOGY; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL MODEL; ASPERGILLOSIS; LUNG MYCOSIS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE;

ANIMALS; ASPERGILLUS FUMIGATUS; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CHRONIC DISEASE; CYTOKINES; EOSINOPHILS; FEMALE; FIBROSIS; GOBLET CELLS; HYPERPLASIA; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOGLOBULIN E; LUNG; LYMPHOCYTES; MICE; MICE, INBRED CBA;

EID: 0034132033     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64775-X     Document Type: Article

References (38)

1. Is asthma a fibrotic disease?
2. Eosinophil-associated TGF-β1 mRNA expression, and airways fibrosis in bronchial asthma
3. Airway inflammation and structural changes in airway hyper-responsiveness and asthma: An overview
4. Mucin in disease. Modification of mucin gene expression in airway disease
5. Subepithelial fibrosis in the bronchi of asthmatics
6. Potential role for phenotypic modulation of bronchial smooth muscle cells in chronic asthma
7. The pathophysiological role of mucus production in inflammatory airway diseases
8. Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease
9. Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine
10. Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation
11. The natural history of asthma in adults: The problem of irreversibility
12. Temporal role of chemokines in a murine model of cockroach allergen-induced airway hyperreactivity and eosinophilia
13. An improved murine model of asthma: Selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolized allergen
14. Lung inflammation and epithelial changes in a murine model of atopic asthma
15. Allergic bronchopulmonary aspergillosis.An increasingly common disorder among asthmatic patients
16. Aspergillosis and lung defenses
17. Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis
18. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1
19. Role of TNFalpha in pulmonary host defense in murine invasive aspergillosis
20. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation
21. A sensitive ELISA for the detection of human monocyte chemoattractant protein-1 (MCP-1)
22. Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis
23. Allergic bronchopulmonary aspergillosis
24. IgE down regulation, and cytokine induction by Aspergillus antigens in human allergic bronchopulmonary aspergillosis
25. Prolonged evaluation of patients with corticosteroid-dependent asthma stage of allergic bronchopulmonary aspergillosis
26. Serum anti-Aspergillus fumigatus antibodies by immunoblot and ELISA in cystic fibrosis with allergic bronchopulmonary aspergillosis
27. Particulate Aspergillus fumigatus antigens elicit a Th2 response in BALB/c mice
28. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis
29. Asthma: A dynamic disease of inflammation and repair
30. Histological features of the airways in asthma and COPD
31. Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice
32. Th2-induced eotaxin expression and eosinophilia coexist with Th1 responses at the effector stage of lung inflammation
33. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia
34. IFN-γ potentiates the release of TNF-α, and MIP-1α by alveolar macrophages during allergic reactions
35. Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor, and interferon-γ release from alveolar macrophages in asthma
36. Interleukin-13 selectively induces monocyte chemoattractant protein-1 synthesis and secretion by human endothelial cells. Involvement of IL-4R α and Stat6 phosphorylation
37. Interleukin (IL)-4, and IL-13 act on human lung fibroblasts: Implications in asthma
38. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production