Defect in IgV gene somatic hypermutation in Common Variable Immuno-Deficiency syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 22, 1998, Pages 13135-13140

  Levy, Yves ^a,b   Gupta, Neetu ^b   Le Deist, Françoise ^c   Garcia, Corinne ^b   Fischer, Alain ^c   Weill, Jean Claude ^b   Reynaud, Claude Agnès ^b  

^a HENRI MONDOR HOSPITAL   (France)

^b INSERM   (France)

^c HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN;

ADULT; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; COMMON VARIABLE IMMUNODEFICIENCY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; HYPOGAMMAGLOBULINEMIA; IMMUNOGLOBULIN BLOOD LEVEL; MONONUCLEAR CELL; PRIORITY JOURNAL; RECURRENT INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SEQUENCE ANALYSIS;

ADULT; AGAMMAGLOBULINEMIA; AGE OF ONSET; ANTIGENS, CD; ANTIGENS, CD19; B-LYMPHOCYTES; BASE SEQUENCE; BURKITT LYMPHOMA; CHILD; CLONING, MOLECULAR; COMMON VARIABLE IMMUNODEFICIENCY; FLOW CYTOMETRY; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; INTRONS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POINT MUTATION; REFERENCE VALUES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0032573184     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.22.13135     Document Type: Article

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