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Volumn 101, Issue 10, 2003, Pages 4029-4032

Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; GENE PRODUCT; UNCLASSIFIED DRUG; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; PRIMER DNA;

EID: 0038300728     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-10-3175     Document Type: Article
Times cited : (97)

References (25)
  • 1
    • 0033603340 scopus 로고    scopus 로고
    • Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells
    • Muramatsu M, Sankaranand VS, Anant S, et al. Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells. J Biol Chem. 1999;274:18470-18476.
    • (1999) J Biol Chem , vol.274 , pp. 18470-18476
    • Muramatsu, M.1    Sankaranand, V.S.2    Anant, S.3
  • 2
    • 0034264851 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)
    • Revy P, Muto T, Levy Y, et al. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2). Cell. 2000;102:565-575.
    • (2000) Cell , vol.102 , pp. 565-575
    • Revy, P.1    Muto, T.2    Levy, Y.3
  • 3
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol. 2002;20:165-196.
    • (2002) Annu Rev Immunol , vol.20 , pp. 165-196
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 4
    • 0028355650 scopus 로고
    • The pathogenesis of chronic lymphocytic leukemia: Analysis of the antibody repertoire
    • Schroeder HW Jr, Dighiero G. The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. Immunol Today. 1994;15:288-294.
    • (1994) Immunol Today , vol.15 , pp. 288-294
    • Schroeder H.W., Jr.1    Dighiero, G.2
  • 5
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94:1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 6
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94:1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 7
    • 10144259343 scopus 로고    scopus 로고
    • Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells
    • Fais F, Sellars B, Ghiotto F, et al. Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells. J Clin Invest. 1996;98:1659-1666.
    • (1996) J Clin Invest , vol.98 , pp. 1659-1666
    • Fais, F.1    Sellars, B.2    Ghiotto, F.3
  • 8
    • 0030017254 scopus 로고    scopus 로고
    • IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations
    • Efremov DG, Ivanovski M, Batista FD, Pozzato G, Burrone OR. IgM-producing chronic lymphocytic leukemia cells undergo immunoglobulin isotype-switching without acquiring somatic mutations. J Clin Invest. 1996;98:290-298.
    • (1996) J Clin Invest , vol.98 , pp. 290-298
    • Efremov, D.G.1    Ivanovski, M.2    Batista, F.D.3    Pozzato, G.4    Burrone, O.R.5
  • 9
    • 0036933015 scopus 로고    scopus 로고
    • Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells
    • Oppezzo P, Magnac C, Bianchi S, et al. Do CLL B cells correspond to naive or memory B-lymphocytes? evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells. Leukemia, 2002;16:2438-2446.
    • (2002) Leukemia , vol.16 , pp. 2438-2446
    • Oppezzo, P.1    Magnac, C.2    Bianchi, S.3
  • 11
    • 0035940511 scopus 로고    scopus 로고
    • A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
    • Kinoshita K, Harigai M, Fagarasan S, Muramatsu M, Honjo T. A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs. Proc Natl Acad Sci U S A. 2001;98:12620-12623.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12620-12623
    • Kinoshita, K.1    Harigai, M.2    Fagarasan, S.3    Muramatsu, M.4    Honjo, T.5
  • 12
  • 13
    • 0012105085 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase (AID) expression in B-CLL
    • Albesiano E, Damle R, Steven L, et al. Activation-induced cytidine deaminase (AID) expression in B-CLL [abstract]. Blood. 2002;100:99a.
    • (2002) Blood , vol.100
    • Albesiano, E.1    Damle, R.2    Steven, L.3
  • 14
    • 0034837614 scopus 로고    scopus 로고
    • Association between a new polymorphism in the activation-induced cytidine deaminase gene and atopic asthma and the regulation of total serum IgE levels
    • Noguchi E, Shibasaki M, Inudou M, et al. Association between a new polymorphism in the activation-induced cytidine deaminase gene and atopic asthma and the regulation of total serum IgE levels. J Allergy Clin Immunol. 2001;108:382-386.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 382-386
    • Noguchi, E.1    Shibasaki, M.2    Inudou, M.3
  • 15
    • 0036884414 scopus 로고    scopus 로고
    • Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells
    • Cerutti A, Zan H, Kim E, et al. Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells. J Immunol. 2002;169:6594-6603.
    • (2002) J Immunol , vol.169 , pp. 6594-6603
    • Cerutti, A.1    Zan, H.2    Kim, E.3
  • 16
    • 0037128169 scopus 로고    scopus 로고
    • Activation-induced deaminase (AID) - Directed hypermutation in the immunoglobulin Smu region: Implication of AID involvement in a common step of class switch recombination and somatic hypermutation
    • Nagaoka H, Muramatsu M, Yamamura N, Kinoshita K, Honjo T. Activation-induced deaminase (AID) - directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation. J Exp Med. 2002;195:529-534.
    • (2002) J Exp Med , vol.195 , pp. 529-534
    • Nagaoka, H.1    Muramatsu, M.2    Yamamura, N.3    Kinoshita, K.4    Honjo, T.5
  • 17
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
    • Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 2000;102:553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1    Kinoshita, K.2    Fagarasan, S.3    Yamada, S.4    Shinkai, Y.5    Honjo, T.6
  • 18
    • 0036234455 scopus 로고    scopus 로고
    • Somatic hypermutation of immunoglobulin genes: Merging mechanisms for genetic diversity
    • Papavasiliou FN, Schatz DG. Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity. Cell. 2002;109(suppl):S35-S44.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Papavasiliou, F.N.1    Schatz, D.G.2
  • 19
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
    • Petersen-Mahrt SK, Harris RS, Neuberger MS. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 2002;418:99-103.
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 20
    • 0037026482 scopus 로고    scopus 로고
    • Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
    • [advance online publication]; July
    • Di Noia J., Neuberger S. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature [advance online publication). 2002;July 31:1-6.
    • (2002) Nature , vol.31 , pp. 1-6
    • Di Noia, J.1    Neuberger, S.2
  • 21
    • 0037074975 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas
    • Martin A, Bardwell PD, Woo CJ, Fan M, Shulman MJ, Scharff MD. Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas. Nature. 2002;415:802-806.
    • (2002) Nature , vol.415 , pp. 802-806
    • Martin, A.1    Bardwell, P.D.2    Woo, C.J.3    Fan, M.4    Shulman, M.J.5    Scharff, M.D.6
  • 22
    • 0037076967 scopus 로고    scopus 로고
    • AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts
    • Yoshikawa K, Okazaki IM, Eto T, et al. AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science. 2002;296:2033-2036.
    • (2002) Science , vol.296 , pp. 2033-2036
    • Yoshikawa, K.1    Okazaki, I.M.2    Eto, T.3
  • 23
    • 0038000002 scopus 로고    scopus 로고
    • AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
    • Faili A, Aoufouchi S, Gueranger Q, et al. AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line [abstract]. Nat Immunol. 2002;29:29.
    • (2002) Nat Immunol , vol.29 , pp. 29
    • Faili, A.1    Aoufouchi, S.2    Gueranger, Q.3
  • 24
    • 0036715714 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intracional immunoglobulin V(H)DJ(H) gene diversification
    • Gurrieri C, McGuire P, Zan H, et al. Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intracional immunoglobulin V(H)DJ(H) gene diversification. J Exp Med. 2002;196;629-639.
    • (2002) J Exp Med , vol.196 , pp. 629-639
    • Gurrieri, C.1    McGuire, P.2    Zan, H.3
  • 25
    • 0036732786 scopus 로고    scopus 로고
    • Does AID need another aid?
    • Honjo T. Does AID need another aid? Nat Immunol. 2002;3:800-801.
    • (2002) Nat Immunol , vol.3 , pp. 800-801
    • Honjo, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.