Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium

American Journal of Physiology - Cell Physiology

Volumn 284, Issue 4 53-4, 2003, Pages

  Kucharzik, Torsten ^a   Gewirtz, Andrew T ^a   Merlin, Didier ^a   Madara, James L ^a   Williams, Ifor R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Eicosanoid; Epitope tag; G protein coupled receptor; Polarized epithelium

Indexed keywords

CELL SURFACE PROTEIN; CELL SURFACE RECEPTOR; CHEMOKINE; EPITOPE; FORMYLPEPTIDE RECEPTOR LIKE 1; G PROTEIN COUPLED RECEPTOR; ICOSANOID; INTERLEUKIN 8; LIPOXIN A; MEMBRANE PROTEIN; MONTELUKAST; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; CYSTEINYL LEUKOTRIENE RECEPTOR 2; FORMYLPEPTIDE RECEPTOR; FPRL1 PROTEIN, HUMAN; HYDROXYICOSATETRAENOIC ACID; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXIN; LIPOXIN RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT; QUINOLINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANTIINFLAMMATORY ACTIVITY; APICAL MEMBRANE; ARTICLE; BASEMENT MEMBRANE; BASOLATERAL MEMBRANE; BIOTINYLATION; CALCIUM CELL LEVEL; CELL POLARITY; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; MOLECULAR INTERACTION; ONCOGENE C MYC; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; INTESTINE MUCOSA; METABOLISM; PHYSIOLOGY; RETROVIRUS; TISSUE DISTRIBUTION;

ACETATES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; GENETIC VECTORS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; INTERLEUKIN-8; INTESTINAL MUCOSA; LEUKOTRIENE ANTAGONISTS; LIPOXINS; MEMBRANE PROTEINS; QUINOLINES; RECEPTORS, CELL SURFACE; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LEUKOTRIENE; RECEPTORS, LIPOXIN; RETROVIRIDAE; TISSUE DISTRIBUTION; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037391334     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00507.2001     Document Type: Article

References (32)

1. Beau I, Groyer-Picard MT, Le Bivic A, Vannier B, Loosfelt H, Milgrom E, and Misrahi M. The basolateral localization signal of the follicle-stimulating hormone receptor. J Biol Chem 273: 18610-18616, 1998.
2. Brown D and Breton S. Sorting proteins to their target membranes. Kidney Int 57: 816-824, 2000.
3. 4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem 276: 21585-21593, 2001.
4. Claria J and Serhan CN. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA 92: 9475-9479, 1995.
5. Dharmsathaphorn K and Madara JL. Established intestinal cell lines as model systems for electrolyte transport studies. Methods Enzymol 192: 354-389, 1990.
6. Eckmann L, Jung HC, Schurer-Maly C, Panja A, Morzycka-Wroblewska E, and Kagnoff MF. Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin 8. Gastroenterology 105: 1689-1697, 1993.
7. Eckmann L, Kagnoff MF, and Fierer J. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun 61: 4569-4574, 1993.
8. 4 receptor. J Exp Med 180: 253-260, 1994.
9. 4, and their analogs selectively downregulate PMN azurophilic degranulation. Am J Physiol Cell Physiol 276: C988-C994, 1999.
10. 4 analogs. J Clin Invest 101: 1860-1869, 1998.
11. 2+-mediated activation of the NF-κB pathway. J Clin Invest 105: 79-92, 2000.
12. Gewirtz AT, Simon PO Jr, Schmitt CK, Taylor LJ, Hagedorn CH, O'Brien AD, Neish AS, and Madara JL. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. J Clin Invest 107: 99-109, 2001.
13. 4 antagonize TNF-α-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-α-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo. J Immunol 167: 2772-2780, 2001.
14. 4 receptor that is regulated by interleukin (IL)-13 and interferon γ and inhibits tumor necrosis factor α-induced IL-8 release. J Exp Med 187: 1285-1294, 1998.
15. 4 and regulation of vascular and inflammatory responses. Am J Pathol 158: 3-9, 2001.
16. Levy BD, Clish CB, Schmidt B, Gronert K, and Serhan CN. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol 2: 612-619, 2001.
17. Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, and Evans JF. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399: 789-793, 1999.
18. Matter K, Yamamoto EM, and Mellman I. Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells. J Cell Biol 126: 991-1004, 1994.
19. Matthews JB, Smith JA, Tally KJ, Awtrey CS, Nguyen H, Rich J, and Madara JL. Na-K-2Cl cotransport in intestinal epithelial cells. Influence of chloride efflux and F-actin on regulation of cotransporter activity and bumetanide binding. J Biol Chem 269: 15703-15709, 1994.
20. McCarthy JB, Lim ST, Elkind NB, Trimmer JS, Duvoisin RM, Rodriguez-Boulan E, and Caplan MJ. The C-terminal tail of the metabotropic glutamate receptor subtype 7 is necessary but not sufficient for cell surface delivery and polarized targeting in neurons and epithelia. J Biol Chem 276: 9133-9140, 2001.
21. McCormick BA, Colgan SP, Delp-Archer C, Miller SI, and Madara JL. Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils. J Cell Biol 123: 895-907, 1993.
22. 4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors. J Biol Chem 275: 27566-27575, 2000.
23. Merlin D, Si-Tahar M, Sitaraman SV, Eastburn K, Williams I, Liu X, Hediger MA, and Madara JL. Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: transport of bacterial peptides influences expression of MHC class I molecules. Gastroenterology 120: 1666-1679, 2001.
24. Mostov KE, Verges M, and Altschuler Y. Membrane traffic in polarized epithelial cells. Curr Opin Cell Biol 12: 483-490, 2000.
25. Nadler LS, Kumar G, and Nathanson NM. Identification of a basolateral sorting signal for the M3 muscarinic acetylcholine receptor in Madin-Darby canine kidney cells. J Biol Chem 276: 10539-10547, 2001.
26. Nussenzveig DR, Matos MD, and Thaw CN. Human calcitonin receptor is directly targeted to and retained in the basolateral surface of MDCK cells. Am J Physiol Cell Physiol 275: C1264-C1276, 1998.
27. Saunders C, Keefer JR, Bonner CA, and Limbird LE. Targeting of G protein-coupled receptors to the basolateral surface of polarized renal epithelial cells involves multiple, non-contiguous structural signals. J Biol Chem 273: 24196-24206, 1998.
28. Schulein R, Lorenz D, Oksche A, Wiesner B, Hermosilla R, Ebert J, and Rosenthal W. Polarized cell surface expression of the green fluorescent protein-tagged vasopressin V2 receptor in Madin Darby canine kidney cells. FEBS Lett 441: 170-176, 1998.
29. 4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 34: 14609-14615, 1995.
30. Su SB, Gong W, Gao JL, Shen W, Murphy PM, Oppenheim JJ, and Wang JM. A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J Exp Med 189: 395-402, 1999.
31. 4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J Exp Med 185: 1693-1704, 1997.
32. +-dependent glucose cotransporter (SGLT1): maintenance of surface expression and global transport function with selective perturbation of transport kinetics and polarized expression. J Biol Chem 271: 7738-7744, 1996.