TGF-β in glomerular disease

Mineral and Electrolyte Metabolism

Volumn 24, Issue 2-3, 1998, Pages 168-173

  Shankland, Stuart J ^a   Johnson, Richard J ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Glomerulus; Matrix; Mesangium; Proliferation; TGF

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

CELL PROLIFERATION; CELL SURVIVAL; EXTRACELLULAR MATRIX; GLOMERULOPATHY; MESANGIUM; PRIORITY JOURNAL; REVIEW;

ANIMALS; CELL DIVISION; CELL SURVIVAL; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GLOMERULAR MESANGIUM; HUMANS; KIDNEY DISEASES; KIDNEY GLOMERULUS; TRANSFORMING GROWTH FACTOR BETA;

GLOMERULUS;

EID: 0031884315     PISSN: 03780392     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057366     Document Type: Review

References (65)

1. Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD, Ruoslahti E: Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease. Nature 1992;360: 361-364.
2. Johnson RJ, Floege J, Couser WG, Alpers CE: Role of platelet-derived growth factor in glomerular disease. J Am Soc Nephrol 1993;4: 119-128.
3. Abboud HE: Growth factors in glomerulonephritis. Kidney Int 1993;43:252-267.
4. Border W, Noble N: Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994; 331:1286-1292.
5. Border WA, Okuda S, Languino LR, Ruoslahti E: Transforming growth factor-beta regulates production of proteoglycans by mesangial cells. Kidney Int 1990;37:689-695.
6. Kasinath BS: Glomerular endothelial cell proteoglycans: Regulation by TGF-beta 1. Arch Biochem Biophys 1993;305:370-377.
7. Nakamura T, Miller D, Ruoslahti E, Border WA: Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-beta 1. Kidney Int 1992; 41:1213-1221.
8. McKay N, Khong T, Haites N, Power D: The effect of transforming growth factor beta 1 on mesangial cell fibronectin synthesis: Increased incorporation into the extracellular matrix and reduced pi but no effect on alternative splicing. Exp Mol Pathol 1993;59:211-224.
9. Tomooka S, Border WA, Marshall BC, Noble NA: Glomerular matrix accumulation is linked to inhibition of the plasmin protease system. Kidney Int 1992;42:1462-1469.
10. Wong A, Cortez S, Baricos W: Role of plasmin and gelatinase in extracellular matrix degradation by cultured rat mesangial cells. Renal Fluid Electrolyte Physiol 1992;32:F1112-F1118.
11. Edwards D, Murphy G, Reynolds J, Whitman S, Docherty A, Angel P, Heath J: Transforming growth factor β modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987;6:1899-1904.
12. Marti HP, Lee L, Kashigarian M, Lovett DH: Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase. Am J Pathol 1994;144: 82-94.
13. Yamamoto T, Wilson CB: Quantitative and qualitative studies of antibody-induced mesangial cell damage in the rat. Kidney Int 1987;32: 514-525.
14. Okuda S, Languino LR, Ruoslahti E, Border WA: Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis: Possible role in expansion of the mesangial extracellular matrix. J Clin Invest 1990;86:453-462.
15. Yamamoto T, Noble NA, Miller DE, Border WA: Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis. Kidney Int 1994;45:916-927.
16. Barnes J, Abboud H: Temporal expression of autocrine growth factors corresponds to morphological features of mesangial proliferation in habu snake venom-induced glomerulonephritis. Am J Pathol 1993;143:1366-1376.
17. Nakamura T, Ebihara I, Fukui M, Osada S, Nagaoka I, Horikoshi S, Tomino Y, Koide H: Messenger RNA expression for growth factors in glomeruli from focal glomerular sclerosis. Clin Immunol Immunopathol 1993;66:33-42.
18. Tamaki K, Okuda S, Ando T, Iwamoto T, Nakayama M, Fujishima M: TGF-beta 1 in glomerulosclerosis and interstitial fibrosis of adriamycin nephropathy. Kidney Int 1994;45: 525-536.
19. Lee LK, Meyer TW, Pollock AS, Lovett DH: Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest 1995;96:953-964.
20. Lianos EA, Orphanos V, Cattell V, Cook T, Anagnou N: Glomerular expression and cell origin of transforming growth factor-beta 1 in anti-glomerular basement membrane disease. Am J Med Sci 1994;307:1-5.
21. Shankland SJ, Ly H, Thai K, Scholey JW: Increased glomerular capillary pressure alters glomerular cytokine expression. Circ Res 1994; 75:844-853.
22. Tamaki K, Okuda S, Nakayama M, Yanagida T, Fujishima M: Transforming growth factor-beta 1 in hypertensive renal injury in Dahl salt-sensitive rats. J Am Soc Nephrol 1996;7:2578-2589.
23. Ding G, Pesek Diamond I, Diamond JR: Cholesterol, macrophages, and gene-expression of TGF-beta 1 and fibronectin during nephrosis. Am J Physiol 1993;264:F577-F584.
24. Shankland SJ, Pippin J, Pichler RH, Gordon KL, Friedman S, Gold LI, Johnson RJ, Couser WG: Differential expression of transforming growth factor-beta isoforms and receptors in experimental membranous nephropathy. Kidney Int 1996;50:116-124.
25. Yoshimura K, Takemura T, Murakami K, Okada M, Hino S, Miyamato H, Maki S: Transforming growth factor-β protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 1993;68:154-163.
26. Floege J, Johnson RJ, Gordon K, Yoshimura A, Campbell C, Iruela Arispe L, Alpers CE, Couser WG: Altered glomerular extracellular matrix synthesis in experimental membranous nephropathy. Kidney Int 1992;42:573-585.
27. Bodi I, Kimmel P, Abraham A, Svetkey L, Klotman P, Kopp J: Renal TGF-β in HIV-associated kidney diseases. Kidney Int 1997;51: 1568-1577.
28. Waldherr R, Noronha I, Niemir Z, Kruger C, Stein H, Stumm G: Expression of cytokines and growth factors in human glomerulonephritides. Pediatr Nephrol 1993;7:471-478.
29. Yamamoto T, Noble NA, Cohen AH, Nast CC, Hishida A, Gold LI, Border WA: Expression of transforming growth factor-beta isoforms in human glomerular diseases. Kidney Int 1996; 49:461-469.
30. Yoshioka K, Takemura T, Murakami K, Okada M, Hino S, Miyamoto H, Maki S: Transforming growth factor-beta protein and mRNA in glomeruli in normal and diseased human kidneys. Lab Invest 1993;68:154-163.
31. Lai E, Hugo C, Couser W, Johnson RJ, Shankland S: Differential expression of transforming growth factor-β (TGF-β) isoforms and receptors in experimental mesangial proliferative glomerulonephritis (MPGN) (abstract). J Invest Med 1997;45:157A.
32. Terrell TG, Working PK, Chow CP, Green JD: Pathology of recombinant human transforming growth factor-beta 1 in rats and rabbits. Int Rev Exp Pathol 1993;34:43-67.
33. Kopp J, Factor V, Mozes M, Nagy P, Sanderson N, Bottinger E, Klotman P, Thorgefrsson S: Transgenic mice with increased plasma levels of TGF-β1 develop progressive renal disease. Lab Invest 1996;74:991-1003.
34. Isaka Y, Fujiwara Y, Ueda N, Kaneda Y, Kamada T, Imai E: Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney. J Clin Invest 1993;92: 2597-2601.
35. Border WA, Okuda S, Languino LR, Sporn MB, Ruoslahti E: Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1. Nature 1990;346: 371-374.
36. Akagi Y, Isaka Y, Arai M, Kaneko T, Takenaka M, Moriyama T, Kaneda Y, Ando A, Orita Y, Kamada T, Ueda N, Imai E: Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int 1996;50:148-155.
37. Isaka Y, Brees DK, Ikegaya K, Kaneda Y, Imai E, Noble NA, Border WA: Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat Med 1996;2: 418-423.
38. McCaffrey T, Falcone D, Vincente D, Du B, Consigli S, Borth W: Protection of transforming growth factor-β1 activity by heparin and fucoidan. J Cell Physiol 1994;159:51-59.
39. Floege J, Eng E, Young BA, Couser WG, Johnson RJ: Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis. Kidney Int 1993;43:369-380.
40. MacKay K, Striker LJ, Staufer JW, Doi T, Agodoa LY, Striker GE: Transforming growth factor-beta: Murine glomerular receptors and responses of isolated glomerular cells. J Clin Invest 1989;83:1160-1167.
41. Adler S, Chen X, Eng B: Control of rat glomerular epithelial cell growth in vitro. Kidney Int 1990;37:1048-1054.
42. Jaffer F, Saunders C, Shultz P, Throckmorton D, Weinshell E, Abboud H: Regulation of mesangial cell growth by polypeptide mitogens. Am J Pathol 1989;135:261-269.
43. Kaname S, Uchida S, Ogata E, Kurokawa K: Autocrine secretion of transforming growth factor-beta in cultured rat mesangial cells. Kidney Int 1992;42:1319-1327.
44. Schoecklmann H, Rupprecht H, Zauner I, Sterzel R: TGF-β1-induced cell cycle arrest in renal mesangial cells involves inhibition of cyclin E-cdk 2 activation and retinoblastoma protein phosphorylation. Kidney Int 1997;51:1228-1236.
45. Kip1. Kidney Int 1997;51:1088-1099.
46. Hugo C, Pichler R, Roberts D, Couser W, Johnson R: Differential effects of thrombospondin 1 (TSP1) peptides in experimental mesangial proliferative disease (abstract). J Am Soc Nephrol 1996;7:1734.
47. Choi M, Kim E-G, Huang Q, Ballermann B: Rat mesangial cell hypertrophy in response to transforming growth factor-β1. Kidney Int 1993;44:948-958.
48. Pintavorn P, Ballermann B: TGF-β and the endothelium during immune injury. Kidney Int 1997;51:1401-1412.
49. Choi ME, Ballermann BJ: Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-beta receptors. J Biol Chem 1995;270:21144-21150.
50. Kitamura M, Suto T: TGF-β and glomerulonephritis: Anti-inflammatory versus prosclerotic actions. Nephrol Dial Transplant 1997;12: 669-679.
51. Böttinger E, Letterio J, Roberts A: Biology of TGF-β in knockout and transgenic mouse models. Kidney Int 1997;51:1355-1360.
52. Letterio JJ, Geiser AG, Kulkarni AB, Dang H, Kong L, Nakabayashi T, Mackall CL, Gress RE, Roberts AB: Autoimmunity associated with TGF-betal-deficiency in mice is dependent on MHC class II antigen expression. J Clin Invest 1996;98:2109-2119.
53. Dang H, Geiser AG, Letterio JJ, Nakabayashi T, Kong L, Fernandes G, Talal N: SLE-like autoantibodies and Sjogren's syndrome-like lymphoproliferation in TGF-beta knockout mice. J Immunol 1995;155:3205-3212.
54. Kitamura M, Suto T, Yokoo T, Shimizu F, Fine LG: Transforming growth factor-beta 1 is the predominent paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells. J Immunol 1996;156:2964-2971.
55. Floege J, Radeke H, Johnson R: Glomerular cells in vitro versus the glomerulus in vivo. Kidney Int 1994;45:360-368.
56. Johnson RJ, Iida H, Alpers CE, Majesky MW, Schwartz SM, Pritzi P, Gordon K, Gown AM: Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis: Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 1991; 87:847-858.
57. Desmouliere A, Geinoz A, Gabbiani F, Gabbiani G: Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 1993;122:103-111.
58. Abboud H, Walker K, Snyder S, Bonewald L: Regulation of transforming growth factor-β by platelet-derived growth factor in human mesangial cells (abstract). Clin Res 1991;39: 358A.
59. Kagami S, Border WA, Miller DE, Noble NA: Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 1994; 93:2431-2437.
60. Pichler R, Bassuk J, Hugo C, Reed M, Eng E, Gordon K, Pippin J, Alpers C, Couser W, Sage E, Johnson R: SPARC is expressed by mesangial cells in experimental mesangial proliferative nephritis and inhibits platelet-derived-growth-factor-mediated mesangial cell proliferation in vitro. Am J Pathol 1996;148:1153-1167.
61. Munger J, Harpel J, Gleizes P-E, Mazzieri R, Nunes R, Rifkin D: Latent transforming growth factor-β: Structural features and mechanisms of activation. Kidney Int 1997;51:1376-1382.
62. Eddy A, Giachelli C, McCulloch L, Liu E: Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinura. Kidney Int 1995; 1995:1546-1557.
63. Schultz-Cherry S, Ribeiro S, Gentry L, Murphy-Ullrich J: Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system. J Biol Chem 1994;269:26775-26782.
64. Hugo C, Pichler R, Meek R, Gordon K, Kyriakides T, Floege J, Bornstein P, Couser W, Johnson R: Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo. Kidney Int 1995;48: 1846-1856.
65. Hugo C, Pichler R, Shankland S, Couser W, Johnson R: Thrombospondin (TSP1) precedes and predicts tubulo-interstitial fibrosis in glomerular disease (abstract). J Am Soc Nephrol 1995;6:897.