IFN-γ production by intrinsic renal cells and bone marrow-derived cells is required for full expression of crescentic glomerulonephritis in mice

Journal of Immunology

Volumn 168, Issue 8, 2002, Pages 4135-4141

  Timoshanko, Jennifer R ^a   Holdsworth, Stephen R ^a   Kitching, A Richard ^a   Tipping, Peter G ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; IRRADIATION; KIDNEY CELL; KIDNEY TUBULE CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; SKIN ALLERGY;

EID: 0037090075     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.8.4135     Document Type: Article

References (46)

1. Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis
2. Interleukin-12 from intrinsic cells is an effector of renal injury in crescentic glomerulonephritis
3. Regulation of the interleukin (IL)-I2R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
4. Interleukin-12 and interferon-γ: Do they always go together?
5. Identification of IFN-γ producing cells in IL-12/IL-18 treated mice
6. Expression of IFN-γ in cerebrovascular endothelial cells from aged mice
7. Dual label immunohistochemical study of interleukin-4 and interferon-γ-expressing cells within the pancreas of the NOD mouse during disease acceleration with cyclophosphamide
8. Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: The roles of cytokines and CD40
9. Regulation of Th1- and Th2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle
10. Multiple defects of immune cell function in mice with disrupted interferon-γ genes
11. IFN-α mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis
12. Lymphocyte recrutiment in delayed type hypersensitivity: The role of IFN-γ
13. Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice
14. Expression of cytokines and growth factors in human glomerulonephritides
15. Phenotypic characterization of cytokine expression in patients with IgA nephropathy
16. Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice
17. Crescentic glomerulonephritis in interferon-γ receptor deficient mice
18. Increased susceptibility to immunologically mediated glomerulonephritis in IFN-γ-deficient mice
19. Regulation of MHC class I expression by inflammatory cytokines in rat mesangial cells
20. Glomerular mesangial cells in local inflammation: Induction of the expression of MHC class II antigens by IFN-γ
21. Interferon-γ stimulates the secretion of IL-1, but not of IL-6 by glomerular mesangial cells
22. Regulation of monocyte chemoattractant protein-1 and macrophage colony-stimulating factor-1 by IFN-γ, tumor necrosis factor-α, IgG aggregates, and cAMP in mouse mesangial cells
23. IFN-γ and LPS differentially modulate class II MHC and B7-1 expression on murine renal tubular epithelial cells
24. TGF-β1 down-regulates induced expression of both class II MHC and B7-1 on primary murine renal tubular epithelial cells
25. MHC class II, antigen presentation and tumor necrosis factor in renal epithelial cells
26. Enhanced MHC class II expression in renal proximal tubules precedes loss of renal function in MRL/lpr mice with lupus nephritis
27. Differing regulation and function of ICAM-1 and class II antigens on renal tubular cells
28. Induction of MHC class II molecules HLADR, -DP and -DQ and ICAM-1 in human podocytes by γ-interferon
29. Podocyte expression of MHC class I and II and intercellular adhesion molecule-1 (ICAM-1) in experimental pauciimmune crescentic glomerulonephritis
30. Immunogenicity of Ly5 (CD45)-antigens hampers long-term engraftment following minimal conditioning in a murine bone marrow transplant model
31. Detection of engraftment and chimerism after bone marrow transplantation by in situ hybridization using a Y-chromosome specific probe
32. Evidence for delayedtype hypersensitivity mechanisms in glomerular crescent formation
33. Immune modulation with interleukin-4 and interleukin-10 prevents crescent formation and glomerular injury in experimental glomerulonephritis
34. kip1 safeguards against inflammatory injury
35. Prevention of crescentic glomerulonephritis in SCG/Kj mice by bone marrow transplantation
36. P-selectin deficiency exacerbates experimental glomerulonephritis: A protective role for endothelial P-selectin in inflammation
37. Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen
38. Crescentic glomerulonephritis in CD4- and CD8-deficient mice: Requirement for CD4 but not CD8 cells
39. Disturbed MHC regulation in the IFN-γ knock-out mouse: Evidence for three states of MHC expression with distinct roles for IFN-γ
40. Interferon-γ induces class II antigen expression on cultured rat mesangial smooth muscle cells
41. Sulfationdependent down-regulation of interferon-γ-induced major histocompatibility complex class I and II and intracellular adhesion molecule-1 expression on tubular and endothelial cells by glycosaminoglycans
42. Activation of autoreactive T-lymphocytes by cultured syngeneic glomerular mesangial cells
43. Mesangial cell accessory functions: Mediation by intracellular adhesion molecule-1
44. Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL/lpr mice
45. Lymphocytederived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells
46. lpr mice