RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors

Biochemical and Biophysical Research Communications

Volumn 316, Issue 3, 2004, Pages 618-627

  Louro, Rodrigo ^a   Nakaya, Helder I ^a   Paquola, Apuã C M ^a   Martins, Elizabeth A L ^b   Da Silva, Aline M ^a   Verjovski Almeida, Sergio ^a   Reis, Eduardo M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

Author keywords

Prostate cancer; Ras related GTPases; Tumor suppressor

Indexed keywords

GUANOSINE TRIPHOSPHATASE; RAS PROTEIN;

ARTICLE; CANCER; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; GENE LOCUS; GENE MAPPING; GENETIC CODE; GENETIC IDENTIFICATION; GENOME; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; MULTIGENE FAMILY; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE TUMOR; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; UNINDEXED SEQUENCE;

ADP-RIBOSYLATION FACTORS; AMINO ACID SEQUENCE; BLOTTING, NORTHERN; CLONING, MOLECULAR; CONSERVED SEQUENCE; DOWN-REGULATION; EXPRESSED SEQUENCE TAGS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; GTP PHOSPHOHYDROLASES; HUMANS; MALE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; PHYLOGENY; PROSTATE; PROSTATIC NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION;

EUKARYOTA;

EID: 1642314462     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.02.091     Document Type: Article

References (33)

1. Bos J.L. Ras-like GTPases. Biochim. Biophys. Acta. 1333:1997;M19-M31.
2. Pasqualato S., Renault L., Cherfils J. Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication. EMBO Rep. 3:2002;1035-1041.
3. Paduch M., Jelen F., Otlewski J. Structure of small G proteins and their regulators. Acta Biochim. Pol. 48:2001;829-850.
4. Oxford G., Theodorescu D. Ras superfamily monomeric G proteins in carcinoma cell motility. Cancer Lett. 189:2003;117-128.
5. Vetter I.R., Wittinghofer A. The guanine nucleotide-binding switch in three dimensions. Science. 294:2001;1299-1304.
6. Adjei A.A. Blocking oncogenic Ras signaling for cancer therapy. J. Natl. Cancer Inst. 93:2001;1062-1074.
7. Boettner B., Van Aelst L. The role of Rho GTPases in disease development. Gene. 286:2002;155-174.
8. Reuther G.W., Der C.J. The Ras branch of small GTPases: Ras family members don't fall far from the tree. Curr. Opin. Cell Biol. 12:2000;157-165.
9. Zohn I.M., Campbell S.L., Khosravi-Far R., Rossman K.L., Der C.J. Rho family proteins and Ras transformation: the RHOad less traveled gets congested. Oncogene. 17:1998;1415-1438.
10. Yu Y., Xu F., Peng H., Fang X., Zhao S., Li Y.et al. NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas. Proc. Natl. Acad. Sci. USA. 96:1999;214-219.
11. Luo R.Z., Fang X., Marquez R., Liu S.Y., Mills G.B., Liao W.S., Yu Y., Bast R.C. ARHI is a Ras-related small G-protein with a novel N-terminal extension that inhibits growth of ovarian and breast cancers. Oncogene. 22:2003;2897-2909.
12. Wani M.A., Denko N.C., Stambrook P.J. Expression of Rap 1 suppresses genomic instability of H-ras transformed mouse fibroblasts. Somat. Cell Mol. Genet. 23:1997;123-133.
13. Finlin B.S., Gau C.L., Murphy G.A., Shao H., Kimel T., Seitz R.S.et al. RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer. J. Biol. Chem. 276:2001;42259-42267.
14. Ellis C.A., Vos M.D., Howell H., Vallecorsa T., Fults D.W., Clark G.J. Rig is a novel Ras-related protein and potential neural tumor suppressor. Proc. Natl. Acad. Sci. USA. 99:2002;9876-9881.
15. Adjei A.A., Mauer A., Bruzek L., Marks R.S., Hillman S., Geyer S.et al. Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer. J. Clin. Oncol. 21:2003;1760-1766.
16. Cox A.D., Der C.J. Ras family signaling: therapeutic targeting. Cancer Biol. Ther. 1:2002;599-606.
17. Strausberg R.L., Simpson A.J., Wooster R. Sequence-based cancer genomics: progress, lessons and opportunities. Nat. Rev. Genet. 4:2003;409-418.
18. Camargo A.A., Samaia H.P., Dias-Neto E., Simao D.F., Migotto I.A., Briones M.R.et al. The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome. Proc. Natl. Acad. Sci. USA. 98:2001;12103-12108.
19. Strausberg R.L. The Cancer Genome Anatomy Project: new resources for reading the molecular signatures of cancer. J. Pathol. 195:2001;31-40.
20. Brentani H., Caballero O.L., Camargo A.A., da Silva A.M., da Silva W.A. Jr., Dias Neto E.et al. The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proc. Natl. Acad. Sci. USA. 100:2003;13418-13423.
21. Paquola A.C.M., Machado A.A., Reis E.M., da Silva A.M., Verjovski-Almeida S. Zerg: a very fast BLAST parser library. Bioinformatics. 19:2003;1035-1036.
22. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25:1997;4876-4882.
23. Page R.D. TreeView: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12:1996;357-358.
24. Wheeler D.L., Church D.M., Federhen S., Lash A.E., Madden T.L., Pontius J.U.et al. Database resources of the national center for biotechnology. Nucleic Acids Res. 31:2003;28-33.
25. Wistow G., Bernstein S.L., Ray S., Wyatt M.K., Behal A., Touchman J.W., Bouffard G., Smith D., Peterson K. Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium. Mol. Vis. 8:2002;185-195.
26. Lee C.H., Della N.G., Chew C.E., Zack D.J. Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. J. Neurosci. 16:1996;6784-6794.
27. Kuge O., Dascher C., Orci L., Rowe T., Amherdt M., Plutner H.et al. Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J. Cell Biol. 125:1994;51-65.
28. Eckley D.M., Schroer T.A. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. Mol. Biol. Cell. 14:2003;2645-2654.
29. Boeck R., Kolakofsky D. Positions +5 and +6 can be major determinants of the efficiency of non-AUG initiation codons for protein synthesis. EMBO J. 13:1994;3017-3608.
30. Tee M.K., Jaffe R.B. A precursor form of vascular endothelial growth factor arises by initiation from an upstream in-frame CUG codon. Biochem. J. 359:2001;219-226.
31. Spoerner M., Herrmann C., Vetter I.R., Kalbitzer H.R., Wittinghofer A. Dynamic properties of the Ras switch I region and its importance for binding to effectors. Proc. Natl. Acad. Sci. USA. 98:2001;4944-4949.
32. Dai Q., Choy E., Chiu V., Romano J., Slivka S.R., Steitz S.A., Michaelis S., Philips M.R. Mammalian prenylcysteine carboxyl methyltransferase is in the endoplasmic reticulum. J. Biol. Chem. 273:1998;15030-15034.
33. Sinensky M. Recent advances in the study of prenylated proteins. Biochim. Biophys. Acta. 1484:2000;93-106.