Mechanistic studies of a novel, human fusion toxin composed of vascular endothelial growth factor (VEGF)121and the serine protease granzyme B: Directed apoptotic events in vascular endothelial cells

Molecular Cancer Therapeutics

Volumn 2, Issue 10, 2003, Pages 949-959

  Liu, Yuying ^a   Cheung, Lawrence H ^a   Thorpe, Philip ^b   Rosenblum, Michael G ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASPASE; CASPASE 3; CASPASE 8; CYTOCHROME C; DNA; DNA FRAGMENT; GRANZYME; GZMB PROTEIN, HUMAN; HYBRID PROTEIN; ISOPROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; ONCOPROTEIN; PROTEIN BAX; PROTEIN BCL 2; SERINE PROTEINASE; TOXIN; VASCULOTROPIN A;

AMINO ACID SEQUENCE; ANIMAL; AORTA; APOPTOSIS; ARTICLE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FLUORESCENCE MICROSCOPY; GENE VECTOR; HUMAN; IC 50; METABOLISM; MITOCHONDRION; MOLECULAR CLONING; MOLECULAR GENETICS; NICK END LABELING; NUCLEOTIDE SEQUENCE; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SWINE; TIME; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; AORTA; APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASE 8; CASPASES; CLONING, MOLECULAR; CYTOCHROMES C; DNA; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENETIC VECTORS; GRANZYMES; HUMANS; IN SITU NICK-END LABELING; INHIBITORY CONCENTRATION 50; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES; SWINE; TIME FACTORS; TOXINS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 1642290611     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

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