Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia

Gene Therapy

Volumn 9, Issue 8, 2002, Pages 503-510

  Pasquini, S ^a,b   Peralta, S ^b   Missiaglia, E ^a   Carta, L ^a   Lemoine, N R ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b WISTAR INSTITUTE   (United States)

Author keywords

Cancer immunotherapy; DNA vaccine; Recombinant vaccinia virus

Indexed keywords

ANIMALS; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COMPLEMENTARITY DETERMINING REGIONS; FEMALE; GENETIC ENGINEERING; GENETIC VECTORS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNOGLOBULIN HEAVY CHAINS; LEUKEMIA, PRE-B-CELL; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; NEOPLASM, RESIDUAL; PLASMIDS; RECOMBINANT FUSION PROTEINS; VACCINES, DNA; VACCINIA;

CANCER VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; DNA VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN IDIOTYPE; PLASMID VECTOR; POLYPEPTIDE; VACCINIA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B CELL LEUKEMIA; CANCER IMMUNIZATION; CANCER INCIDENCE; CANCER RECURRENCE; CANCER RESISTANCE; CANCER SURVIVAL; CELL CLONE; CELLULAR IMMUNITY; CLINICAL PROTOCOL; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENETIC CODE; INOCULATION; LEUKEMIA CELL; MINIMAL RESIDUAL DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TUMOR IMMUNITY; VACCINATION; VACCINIA VIRUS; VIRUS RECOMBINANT;

ANIMALIA; MURINAE; VACCINIA VIRUS; VECTORS;

EID: 85047698677     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301677     Document Type: Article

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